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Showing 1–24 of 32 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Breast Cancer Related Lymphedema Clear all
Not listed Not applicable Interventional

The Effect of Hand Exercises on Upper Limb Volume, Quality of Life, and Hand Function in Breast Cancer Survivors

NCT05983380
View directory record Official record
Conditions
Breast Cancer Lymphedema
Interventions
Hand Mobility and Grip Strengthening Exercises, Usual Care
Other
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
3
States / cities
Albuquerque, New Mexico • Rio Rancho, New Mexico • Santa Fe, New Mexico
Source: ClinicalTrials.gov public record
Updated Apr 16, 2024 · Synced Jul 22, 2026, 3:35 AM EDT
Recruiting Phase 2 Interventional

A Study Evaluating the Feasibility and Compliance of Manual Lymphatic Drainage Comparing Indocyanine-Green (ICG) Guided vs. Traditional Guided in Patients Undergoing Axillary Node Dissection for the Treatment of Breast Cancer

NCT06327490
View directory record Official record
Conditions
Breast Cancer
Interventions
ICG-guided manual lymphatic drainage, Traditional manual lymphatic drainage, Indocyanine green
Procedure · Drug
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 99 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Jul 22, 2026, 3:35 AM EDT
Completed Not applicable Interventional Results available

LLLT Combined With CDT in Breast Cancer-Related Lymphedema

NCT01351376
View directory record Official record
Conditions
Breast Cancer, Lymphedema
Interventions
Low Level Laser Therapy, Low Level Laser
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
21 Years and older · Female only
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
3
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 18, 2019 · Synced Jul 22, 2026, 3:35 AM EDT
Completed Not applicable Interventional Results available

Study Evaluating Flexitouch Plus With Connectivity on Compliance in 30 Patients With Breast Cancer-Related Lymphedema.

NCT04432727
View directory record Official record
Conditions
Breast Cancer Lymphedema
Interventions
Flexitouch Plus with Cellular Connectivity (FT-CC)
Device
Lead sponsor
Tactile Medical
Industry
Eligibility
18 Years and older · Female only
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
3
States / cities
Louisville, Kentucky • Albany, New York • Troy, New York
Source: ClinicalTrials.gov public record
Updated May 23, 2023 · Synced Jul 22, 2026, 3:35 AM EDT
Completed Not applicable Interventional Results available

Immunotherapy for the Treatment of Breast Cancer Related Upper Extremity Lymphedema (BCRL)

NCT02494206
View directory record Official record
Conditions
Breast Cancer, Upper Extremity Lymphedema
Interventions
QBX258
Drug
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 7, 2018 · Synced Jul 22, 2026, 3:35 AM EDT
Recruiting Not applicable Interventional

A Non-randomized, Open-Label Study to Evaluate the Safety and Effectiveness of the Dayspring Technology for Patients With Breast Cancer Related Lymphedema (BCRL) After Lymphatic Surgery

NCT04888975
View directory record Official record
Conditions
Lymphedema, Lymphedema, Breast Cancer, Lymphedema Arm
Interventions
Dayspring Active Wearable Compression System
Device
Lead sponsor
Koya Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated May 19, 2021 · Synced Jul 22, 2026, 3:35 AM EDT
Recruiting Not applicable Interventional

LYMPHA Procedure for the Prevention of Lymphedema After Axillary Lymphadenectomy

NCT05366699
View directory record Official record
Conditions
Lymphedema, Breast Cancer, Lymphedema
Interventions
axillary lymphadenectomy with immediate lymphatic reconstruction (LYMPHA), Axillary lymphadenetomy alone, axillary lymphadenectomy with soft tissue reinforcement
Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2030
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Jul 22, 2026, 3:35 AM EDT
Completed Not applicable Interventional

Clinical Evaluation of a Novel Wearable Compression Technology in the Treatment of Lymphedema, An Open-Label Controlled Study

NCT04659564
View directory record Official record
Conditions
Breast Cancer Related Lymphedema, Lymphedema of Upper Arm, Lymphedema, Quality of Life
Interventions
User of Dayspring device
Device
Lead sponsor
Koya Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
2
States / cities
Los Altos, California • Morgan Hill, California
Source: ClinicalTrials.gov public record
Updated May 31, 2021 · Synced Jul 22, 2026, 3:35 AM EDT
Recruiting No phase listed Observational

Lymphedema Surveillance Study

NCT02743858
View directory record Official record
Conditions
Breast Cancer, Lymphedema
Interventions
Bilateral arm measurements, Body mass index (BMI), Quality of Life Questionnaire, Blood draw
Other · Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
1,250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2027
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Jul 22, 2026, 3:35 AM EDT
Completed No phase listed Observational

Self-Care for Lymphedema in Patients With Breast Cancer

NCT00670644
View directory record Official record
Conditions
Breast Cancer
Interventions
questionnaire administration, survey administration, quality-of-life assessment
Other · Procedure
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 120 Years · Female only
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
3
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 9, 2017 · Synced Jul 22, 2026, 3:35 AM EDT
Completed Phase 4 Interventional

A Comparison of Dermal Autograft to AlloDerm in Breast Reconstruction

NCT01561287
View directory record Official record
Conditions
Mastectomy Related Lymphedema, Breast Reconstruction, Breast Cancer
Interventions
Dermal Autograft, AlloDerm
Procedure
Lead sponsor
University of Kentucky
Other
Eligibility
Female only
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated May 10, 2016 · Synced Jul 22, 2026, 3:35 AM EDT
Completed Not applicable Interventional Results available

Treatment of Breast Cancer-related Lymphedema With a Negative Pressure Device

NCT03252145
View directory record Official record
Conditions
Lymphedema, Secondary, Lymphedema of Upper Limb
Interventions
PhysioTouch, Manual Lymph Drainage (MLD)
Device · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Female only
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 14, 2021 · Synced Jul 22, 2026, 3:35 AM EDT
Enrolling by invitation No phase listed Observational

The BEACON Trial: Diagnostic Tools for Breast Lymphedema After Treatment for Breast Cancer

NCT06900023
View directory record Official record
Conditions
Breast Edema, Breast Lymphedema, Lymphedema, Breast Cancer, Lymphedema
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 15, 2025 · Synced Jul 22, 2026, 3:35 AM EDT
Not yet recruiting Not applicable Interventional

Early Intervention

NCT05326165
View directory record Official record
Conditions
Breast Cancer, Breast Cancer Treatment Related Lymphedema
Interventions
Juzo Compression Sleeve and Glove, Compression Sleeve Sensor
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Jul 22, 2026, 3:35 AM EDT
Active, not recruiting Phase 3 Interventional

Does Immediate Lymphatic Reconstruction Decrease the Risk of Lymphedema After Axillary Lymph Node Dissection

NCT04241341
View directory record Official record
Conditions
Breast Cancer Lymphedema
Interventions
Axillary Lymph Node Dissection with Immediate Lymphatic Reconstruction, Axillary Lymph Node Dissection without Immediate Lymphatic Reconstruction, quality-of-life questionnaires, measured by arm volume
Procedure · Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Jul 22, 2026, 3:35 AM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

LYT-100 in Patients With BCRL

NCT04243837
View directory record Official record
Conditions
Breast Cancer Related Lymphoedema, Lymphoedema
Interventions
LYT-100 BCRL, Placebo BCRL
Drug
Lead sponsor
PureTech
Industry
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
4
States / cities
Duarte, California • Los Angeles, California • Maitland, Florida + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 22, 2024 · Synced Jul 22, 2026, 3:35 AM EDT
Terminated Not applicable Interventional Results available

A Study Evaluating FT-SW in Unilateral Breast Cancer-Related Lymphedema Patients

NCT04073823
View directory record Official record
Conditions
Breast Cancer Related Lymphedema
Interventions
Flexitouch Plus, Flexitouch Plus FT with software modification
Device
Lead sponsor
Tactile Medical
Industry
Eligibility
18 Years and older · Female only
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 17, 2023 · Synced Jul 22, 2026, 3:35 AM EDT
Recruiting No phase listed Observational

Screening For BCRL In Targeted Therapy For Breast Cancer

NCT05142800
View directory record Official record
Conditions
Lymphedema, Lymphedema Arm, Lymphedema of Upper Arm, Lymphedema of Upper Limb, Lymphedema of the Hands, Edema, Edema Arm, Breast Cancer Lymphedema, Breast Cancer Metastatic, Breast Cancer Stage, Breast Cancer
Interventions
Perometer, SOZO device
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
261 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Jul 22, 2026, 3:35 AM EDT
Completed Not applicable Interventional

A Multi-center Randomized Control Cross-over Study to Evaluate the Safety and Effectiveness of the Dayspring Active Wearable Compression Device vs. an Advanced Pneumatic Compression Device for Treating Breast Cancer Related Lymphedema

NCT04908254
View directory record Official record
Conditions
Lymphedema, Lymphedema of Upper Arm, Lymphedema, Breast Cancer
Interventions
Crossover Device (PCD or Dayspring - alternate to first group)
Device
Lead sponsor
Koya Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
2
States / cities
Los Altos, California • Morgan Hill, California
Source: ClinicalTrials.gov public record
Updated Dec 8, 2025 · Synced Jul 22, 2026, 3:35 AM EDT
Recruiting Not applicable Interventional

ILR to Prevent BRCL_MCC 23608

NCT07127003
View directory record Official record
Conditions
Breast Cancer Lymphedema
Interventions
Immediate Lymphatic Reconstruction
Procedure
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
3
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Jul 22, 2026, 3:35 AM EDT
Active, not recruiting Not applicable Interventional

Exploring the Efficacy and Feasibility of the LymphaTech Scanner for Breast Cancer-Related Lymphedema Screening

NCT03861975
View directory record Official record
Conditions
Breast Cancer
Interventions
Breast Cancer-Related Lymphedema Measurements
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Jul 22, 2026, 3:35 AM EDT
Completed Phase 2 Interventional

Massage Therapy for Breast Cancer Treatment-Related Swelling of the Arms

NCT00058851
View directory record Official record
Conditions
Lymphedema
Interventions
Manual lymph drainage, Combined physiotherapy, Compression bandaging
Procedure
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
Not listed
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 18, 2009 · Synced Jul 22, 2026, 3:35 AM EDT
Completed No phase listed Observational

Breast Cancer Lymphedema: Role of Insulin Resistance/FOXC2

NCT00383604
View directory record Official record
Conditions
Lymphedema, Breast Cancer
Interventions
Not listed
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 29, 2013 · Synced Jul 22, 2026, 3:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Bioelectrical Impedance for Self-monitoring of Lymphedema

NCT01385488
View directory record Official record
Conditions
Lymphedema
Interventions
self-monitor arm volume
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
21 Years and older
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 9, 2017 · Synced Jul 22, 2026, 3:35 AM EDT