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ClinicalTrials.gov public records Last synced Oct 2, 2026, 11:35 AM EDT

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Showing 25–48 of 316 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Cardiometabolic Disease Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Replacing Refined Carbohydrates With Healthy Fats on Cardio-metabolic Markers

NCT02695433
View directory record Official record
Conditions
Pre-diabetes, Metabolic Syndrome
Interventions
Active, Control
Dietary Supplement
Lead sponsor
Clinical Nutrition Research Center, Illinois Institute of Technology
Industry
Eligibility
25 Years to 60 Years
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 29, 2021 · Synced Oct 2, 2026, 11:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of a Commercially Available Synbiotic on the Gut Microbiome and Cardiometabolic Health

NCT07515443
View directory record Official record
Conditions
Hypertension, Gut Dysbiosis, Overweight , Obesity
Interventions
Synbiotic, Placebo
Dietary Supplement
Lead sponsor
Southern Utah University
Other
Eligibility
18 Years to 60 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Cedar, Utah
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Oct 2, 2026, 11:35 AM EDT
Active, not recruiting Not applicable Interventional

The Effects of Fresh Mango Consumption on Cardiometabolic Outcomes in Free-living Individuals With Prediabetes

NCT06159543
View directory record Official record
Conditions
Hyperglycemia, Dyslipidemias, Insulin Resistance, Inflammation, Oxidative Stress
Interventions
Mango
Behavioral
Lead sponsor
Loma Linda University
Other
Eligibility
40 Years to 60 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Oct 2, 2026, 11:35 AM EDT
Not yet recruiting Not applicable Interventional

Beta-2 Adrenergic Receptor Polymorphic Variants: An Endotype of Salt Sensitive Hypertension (Beta2AR).

NCT07832942
View directory record Official record
Conditions
Genetics in Hypertension
Interventions
low sodium diet, high sodium diet, renal plasma flow, SIEA collection
Other · Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 50 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 2, 2026, 11:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Potatoes on Markers of Cardiometabolic Health

NCT03495284
View directory record Official record
Conditions
Type 2 Diabetes Mellitus, Cardiovascular Diseases
Interventions
Potato-based side dish, Refined grain-based
Dietary Supplement
Lead sponsor
Penn State University
Other
Eligibility
25 Years to 75 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 18, 2023 · Synced Oct 2, 2026, 11:35 AM EDT
Recruiting Not applicable Interventional

Prebiotic Inulin for Late-Reproductive Individuals

NCT07724522
View directory record Official record
Conditions
Obesity & Overweight, Perimenopausal Women, Prebiotics, Inulin, Muscle, Skeletal, Cardiovascular Diseases (CVD), Microbiota, Gastrointestinal Microbiome, Dietary Fiber, Women Health, Vascular Health, Insulin Resistance
Interventions
Inulin, Maltodextrin (Placebo)
Dietary Supplement
Lead sponsor
George Washington University
Other
Eligibility
40 Years to 55 Years · Female only
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 2, 2026, 11:35 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Delta GREENS Food is Medicine Intervention

NCT06358859
View directory record Official record
Conditions
Cardiometabolic Risk Factors, Diabetes, High Blood Pressure, Obesity, Nutrition Security
Interventions
Food is Medicine
Other
Lead sponsor
Tufts University
Other
Eligibility
21 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 2, 2026, 11:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effects of Altering Physical Activity on Cardiometabolic Health

NCT01879059
View directory record Official record
Conditions
Insulin Resistance
Interventions
Exercise
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
19 Years to 35 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 8, 2016 · Synced Oct 2, 2026, 11:35 AM EDT
Terminated Phase 2 Interventional

Statin Monotherapy for Treatment of Endocrine Metabolic Disease Risk

NCT03113994
View directory record Official record
Conditions
Spinal Cord Injuries, Osteoporosis, Metabolic Syndrome
Interventions
Rosuvastatin Calcium, Placebo Oral Tablet, Coenzyme Q10, Calcium Carbonate, Vitamin D
Drug · Dietary Supplement
Lead sponsor
Dr. B. Catharine. Craven
Other
Eligibility
18 Years to 60 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 2, 2026, 11:35 AM EDT
Completed Not applicable Interventional Results available

High Intensity Interval Exercise SCI

NCT04940598
View directory record Official record
Conditions
Spinal Cord Injuries, Cardiometabolic Diseases
Interventions
high intensity interval exercise, No-exercise control group
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 65 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 24, 2024 · Synced Oct 2, 2026, 11:35 AM EDT
Not yet recruiting Phase 2Phase 3 Interventional

Postpartum Semaglutide to Reduce Cardiometabolic Risk After Gestational Diabetes Mellitus

NCT07797036
View directory record Official record
Conditions
Gestational Diabetes Mellitus (GDM), Metabolic Syndrome
Interventions
Semaglutide (Wegovy) weekly injection
Drug
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older · Female only
Enrollment
226 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2030
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 2, 2026, 11:35 AM EDT
Completed Phase 4 Interventional Results available

Vascular Inflammation in Psoriasis - Apremilast

NCT03082729
View directory record Official record
Conditions
Psoriasis, Cardiovascular Diseases
Interventions
Apremilast
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
7
States / cities
Los Angeles, California • Rockville, Maryland • Buffalo, New York + 4 more
Source: ClinicalTrials.gov public record
Updated Nov 10, 2022 · Synced Oct 2, 2026, 11:35 AM EDT
Completed Not applicable Interventional Results available

Effect of Vitamin D Supplementation on Inflammation and Cardiometabolic Risk Factors in Obese Adolescents

NCT01217840
View directory record Official record
Conditions
Obesity
Interventions
Drisdol (Ergocalciferol) Vitamin D2, Placebo
Drug
Lead sponsor
Stanford University
Other
Eligibility
11 Years to 17 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Nov 29, 2017 · Synced Oct 2, 2026, 11:35 AM EDT
Recruiting Not applicable Interventional

MegaNatural BP® GSE on Blood Pressure and Cardiometabolic Risk Factors

NCT06555952
View directory record Official record
Conditions
Hypertension, Pre Diabetes
Interventions
MegaNatural-BP SR 150Mg Tablet, Placebo Capsule
Dietary Supplement · Other
Lead sponsor
Clinical Nutrition Research Center, Illinois Institute of Technology
Industry
Eligibility
40 Years to 60 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 2, 2026, 11:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of a Synbiotic on the Gut Microbiota and Adiposity-related Markers in Healthy Overweight Subjects

NCT02151825
View directory record Official record
Conditions
Gut Microbiota, Adiposity
Interventions
Synbiotic, Placebo
Dietary Supplement · Other
Lead sponsor
Texas State University, San Marcos
Other
Eligibility
18 Years to 64 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
San Marcos, Texas
Source: ClinicalTrials.gov public record
Updated May 30, 2014 · Synced Oct 2, 2026, 11:35 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Circadian Intervention to Improve Cardiometabolic Health

NCT05943626
View directory record Official record
Conditions
Cardiometabolic Syndrome, Type 2 Diabetes, Sleep, Time Restricted Feeding, Lifestyle Factors, Overweight and Obesity, Insulin Sensitivity, Eating Habit, Sleep Hygiene
Interventions
Circadian Intervention
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 45 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Oct 2, 2026, 11:35 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Circadian Time Restricted Eating

NCT05628012
View directory record Official record
Conditions
Circadian Rhythm, Cardiometabolic Health, Weight Loss, Cardiovascular Health, Time Restricted Feeding
Interventions
Circadian Based Time Restricted Eating
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 40 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 3, 2024 · Synced Oct 2, 2026, 11:35 AM EDT
Recruiting Not applicable Interventional

Spinal Cord Injury Model Systems (SCIMS) - Education Module

NCT06003686
View directory record Official record
Conditions
Spinal Cord Injuries, Obesity, Cardiometabolic Syndrome
Interventions
PVA Consumer Guide, WebMD
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 70 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
3
States / cities
Washington D.C., District of Columbia • Miami, Florida • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 2, 2026, 11:35 AM EDT
Completed Not applicable Interventional Results available

Mi Puente: My Bridge to Better Cardiometabolic Health and Well-Being

NCT02723019
View directory record Official record
Conditions
Type 2 Diabetes Mellitus, Cardiometabolic Conditions, Behavioral Health Concerns
Interventions
Volunteer Peer Mentor+Behavioral Health Nurse
Behavioral
Lead sponsor
Scripps Whittier Diabetes Institute
Other
Eligibility
18 Years and older
Enrollment
536 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Chula Vista, California
Source: ClinicalTrials.gov public record
Updated Feb 28, 2023 · Synced Oct 2, 2026, 11:35 AM EDT
Enrolling by invitation Not applicable Interventional

To Test the Effectiveness and Implementation Approach of a 3-month PILI Pasifika Program Lifestyle Program With Components of Social Determinants of Health Activities in Real-world Settings (Clinical and Non-clinical Settings) Across 3 Years

NCT07387393
View directory record Official record
Conditions
Cardiometabolic Conditions, Hypertension (HTN), Dyslipidemia, Pre-diabetes, Type 2 Diabetes Mellitus (T2DM), Overweight (BMI > 25), Weight Loss Trial
Interventions
PILI (Partnership for Improving Lifestyle Intervention) Pasifika Program
Behavioral
Lead sponsor
University of Hawaii
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Fayetteville, Arkansas • Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 2, 2026, 11:35 AM EDT
Completed Not applicable Interventional

SUSTAIN: Behavior Change and Nutrition Security for CKMS

NCT06589336
View directory record Official record
Conditions
Stage 2 Cardiovascular-Kidney-Metabolic Syndrome, Cardiovascular Disease Other
Interventions
Dietary changes via Instacart vouchers, Dietary changes via access to Mid-Ohio Farmacy, Behavior changes via access to Health Impact Ohio Hub, Behavioral nutrition counseling, Cooking classes, Dietary changes to Delivery fees
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 11, 2025 · Synced Oct 2, 2026, 11:35 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Project 2: ACHIEVE- HF

NCT05330221
View directory record Official record
Conditions
Heart Failure, Hypertension
Interventions
PAL2, PHARM-PAL2
Behavioral · Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
364 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 2, 2026, 11:35 AM EDT
Enrolling by invitation No phase listed Observational

Adult Sleep Health in the Rural Appalachia and Mississippi Delta Region and Its Relationships With Cardiometabolic Health Disparities.

NCT06336525
View directory record Official record
Conditions
Sleep Apnea, Insomnia, Sleep Deprivation, Sleep Disorders, Circadian Rhythm, Sleepiness, Excessive Daytime, Fatigue
Interventions
Not listed
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
25 Years to 65 Years
Enrollment
3,680 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced Oct 2, 2026, 11:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Magnesium and Vitamin D Supplementation and Cardiometabolic Outcomes

NCT03134417
View directory record Official record
Conditions
Overweight and Obesity, Vitamin D Deficiency, Magnesium Deficiency, Cardiovascular Risk Factor
Interventions
Vitamin D and magnesium, Vitamin D, Placebo
Dietary Supplement
Lead sponsor
Drexel University
Other
Eligibility
30 Years to 70 Years
Enrollment
109 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 27, 2021 · Synced Oct 2, 2026, 11:35 AM EDT