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Showing 1–24 of 56 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Cardiopulmonary Arrest Clear all
Completed Not applicable Interventional Results available

Hemodynamic Effects of Standard Cardiopulmonary Resuscitation (CPR), Active Compression Decompression CPR With an Inspiratory Impedance Device, and Standard CPR With an Intrathoracic Pressure Regulator During Out-of-hospital Cardiac Arrest

NCT01325870
View directory record Official record
Conditions
Cardiac Arrest, Sudden Cardiac Death
Interventions
ACD-CPR, ITPR, S-CPR, Impedance Threshold Device (ITD)
Device · Procedure
Lead sponsor
Advanced Circulatory Systems
Industry
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Kalamazoo, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 11, 2016 · Synced Sep 8, 2026, 9:12 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Just in Time Cardio Pulmonary Resuscitation Trial

NCT05983640
View directory record Official record
Conditions
Cardiopulmonary Arrest With Successful Resuscitation, Educational Problems
Interventions
Video, AHA course
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Foxborough, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 8, 2023 · Synced Sep 8, 2026, 9:12 AM EDT
Terminated Phase 2 Interventional Results available

Treatment of Ventricular Tachyarrhythmias Refractory To Shock With Beta Blockers: The SHOCK and BLOCK Trial

NCT00401882
View directory record Official record
Conditions
Cardiac Arrest, Sudden Cardiac Death, Ventricular Fibrillation, Tachycardia, Ventricular
Interventions
Epinephrine, Metoprolol
Drug
Lead sponsor
David Haines, MD
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated May 24, 2017 · Synced Sep 8, 2026, 9:12 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

An In-Hospital Family Member Cardiopulmonary Resuscitation (CPR) Education Program

NCT01260441
View directory record Official record
Conditions
Cardiac Arrest, Coronary Disease, Cardiovascular Risk Factors
Interventions
CPR Training using the Family and Friends CPR Anytime VSI Kit
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
3
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 31, 2018 · Synced Sep 8, 2026, 9:12 AM EDT
Active, not recruiting Not applicable Interventional

Situation Awareness Incorporating Multidisciplinary Teams Reduce Arrests In the Pediatric ICU

NCT06553534
View directory record Official record
Conditions
In-hospital Cardiac Arrest, Cardiopulmonary Resuscitation
Interventions
SAMURAI PICU Bundle
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
Not listed
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
5
States / cities
Chicago, Illinois • Akron, Ohio • Charleston, South Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 15, 2024 · Synced Sep 8, 2026, 9:12 AM EDT
Completed Phase 3 Interventional Results available

Amiodarone, Lidocaine or Neither for Out-Of-Hospital Cardiac Arrest Due to Ventricular Fibrillation or Tachycardia

NCT01401647
View directory record Official record
Conditions
Cardiac Arrest
Interventions
amiodarone, Lidocaine, Normal saline
Drug · Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
3,024 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
7
States / cities
Birmingham, Alabama • San Diego, California • Portland, Oregon + 4 more
Source: ClinicalTrials.gov public record
Updated Apr 16, 2017 · Synced Sep 8, 2026, 9:12 AM EDT
Completed No phase listed Observational

Evaluation of Efficacy of the Prototype RPC (Rapid Pulse Confirmation) Device in Detecting Return of Pulsatile Flow in Patients Preparing to Separate From CPB (Cardiopulmonary Bypass)

NCT04526249
View directory record Official record
Conditions
Circulatory Failure, Cardiac Arrest
Interventions
rapid pulse confirmation device
Device
Lead sponsor
Michael Kyle Ritchie
Other
Eligibility
18 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Aug 24, 2020 · Synced Sep 8, 2026, 9:12 AM EDT
Completed Not applicable Interventional

Goal-directed CPR Using Cerebral Oximetry

NCT04924985
View directory record Official record
Conditions
Ischemia, Reperfusion Injury
Interventions
Non-Physiological Feedback CPR, Physiological Feedback CPR
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 80 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Sep 8, 2026, 9:12 AM EDT
Completed No phase listed Observational

Aprotinin Use and Renal Outcome in Hypothermic Bypass and Circulatory Arrest for Surgical Repair of Thoracic Aorta.

NCT00405093
View directory record Official record
Conditions
Circulatory Arrest
Interventions
Not listed
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
Not listed
Enrollment
1,250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 18, 2017 · Synced Sep 8, 2026, 9:12 AM EDT
Active, not recruiting Not applicable Interventional

The PulsePoint Study

NCT04806958
View directory record Official record
Conditions
Out-Of-Hospital Cardiac Arrest, Heart Arrest, Heart Diseases, Cardiovascular Diseases
Interventions
PulsePoint notification
Other
Lead sponsor
Dr. Steven Brooks
Other
Eligibility
Not listed
Enrollment
340 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 8, 2026, 9:12 AM EDT
Completed Not applicable Interventional Results available

Therapeutic Hypothermia to Improve Survival After Cardiac Arrest in Pediatric Patients-THAPCA-IH [In Hospital] Trial

NCT00880087
View directory record Official record
Conditions
Cardiac Arrest
Interventions
Therapeutic Hypothermia, Therapeutic Normothermia
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
48 Hours to 18 Years
Enrollment
329 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
25
States / cities
Birmingham, Alabama • Phoenix, Arizona • Loma Linda, California + 21 more
Source: ClinicalTrials.gov public record
Updated Jun 14, 2018 · Synced Sep 8, 2026, 9:12 AM EDT
Withdrawn Phase 3 Interventional Accepts healthy volunteers

Nitrite Infusion in High Risk Patients Undergoing Cardiopulmonary Bypass

NCT03331146
View directory record Official record
Conditions
Acute Kidney Injury
Interventions
Saline, Sodium Nitrite
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 100 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 26, 2018 · Synced Sep 8, 2026, 9:12 AM EDT
Completed Phase 3 Interventional Results available

Therapeutic Hypothermia to Improve Survival After Cardiac Arrest in Pediatric Patients-THAPCA-OH [Out of Hospital] Trial

NCT00878644
View directory record Official record
Conditions
Cardiac Arrest
Interventions
Therapeutic Hypothermia, Therapeutic Normothermia
Procedure · Other
Lead sponsor
University of Michigan
Other
Eligibility
48 Hours to 18 Years
Enrollment
295 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
33
States / cities
Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 29 more
Source: ClinicalTrials.gov public record
Updated Sep 28, 2017 · Synced Sep 8, 2026, 9:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving the Quality of Cardiopulmonary Resuscitation (CPR) During Pediatric Cardiac Arrest

NCT02075450
View directory record Official record
Conditions
Cardiac Arrest
Interventions
CPRcard, Just in Time Video
Device · Other
Lead sponsor
KidSIM Simulation Program
Network
Eligibility
18 Years and older
Enrollment
324 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
7
States / cities
Birmingham, Alabama • New Haven, Connecticut • Chicago, Illinois + 4 more
Source: ClinicalTrials.gov public record
Updated Aug 18, 2015 · Synced Sep 8, 2026, 9:12 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Gathering Evidence on Best Practices for Lay Rescuer CPR Training

NCT05908500
View directory record Official record
Conditions
Cardiac Arrest, Out-Of-Hospital
Interventions
CPR Training, CPR Manikin Type
Behavioral · Device
Lead sponsor
University of Nevada, Reno
Other
Eligibility
Not listed
Enrollment
2,100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
1
States / cities
Reno, Nevada
Source: ClinicalTrials.gov public record
Updated Jun 3, 2025 · Synced Sep 8, 2026, 9:12 AM EDT
Completed Not applicable Interventional Results available

Code Blue Outcomes & Process Improvement Through Leadership Optimization Using Teleintensivists-Simulation

NCT03000829
View directory record Official record
Conditions
Cardiac Arrest
Interventions
Tele-intensivist consultation, Simulated "observation" by ICU physician
Other
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years and older
Enrollment
1,001 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
7
States / cities
American Fork, Utah • Murray, Utah • Ogden, Utah + 3 more
Source: ClinicalTrials.gov public record
Updated May 30, 2024 · Synced Sep 8, 2026, 9:12 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Cardiopulmonary Resuscitation (CPR) Dissemination Study Using Nurses and Volunteers

NCT01252316
View directory record Official record
Conditions
Cardiovascular Risk Factors, Coronary Disease, Cardiac Arrest
Interventions
CPR Training using the Family and Friends CPR Anytime VSI Kit, Implementation of an In-Hospital CPR Training Model
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 31, 2018 · Synced Sep 8, 2026, 9:12 AM EDT
Completed Phase 3 Interventional

Dispatcher-Assisted Resuscitation Trial (DART)

NCT00219687
View directory record Official record
Conditions
Heart Arrest
Interventions
dispatcher-assisted CPR with compressions & ventilations, dispatcher-assisted CPR instructions with compressions only
Other
Lead sponsor
Public Health - Seattle and King County
Government
Eligibility
9 Years and older
Enrollment
5,494 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2012
U.S. locations
2
States / cities
Olympia, Washington • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 28, 2014 · Synced Sep 8, 2026, 9:12 AM EDT
Terminated Not applicable Interventional Results available

Advanced Reperfusion Strategies for Refractory Cardiac Arrest

NCT03880565
View directory record Official record
Conditions
Cardiac Arrest, Extracorporeal Membrane Oxygenation Complication, Ventricular Fibrillation, Pulseless Ventricular Tachycardia, Out-Of-Hospital Cardiac Arrest
Interventions
Early Extracorporeal Membrane Oxygenation (ECMO) Facilitated Resuscitation, Standard Advanced Cardiac Life Support (ACLS) Resuscitation
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 9, 2022 · Synced Sep 8, 2026, 9:12 AM EDT
Completed Not applicable Interventional Results available

Heated Humidified Breathing Circuit Rewarming in Hypothermic Post Cardiopulmonary Bypass Patients.

NCT03697122
View directory record Official record
Conditions
Hypothermia, Rewarming
Interventions
Heated Humidified Breathing Circuit and Forced Air Blanket
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 14, 2020 · Synced Sep 8, 2026, 9:12 AM EDT
Completed No phase listed Observational Results available

Verification of Prediction Algorithm

NCT02863666
View directory record Official record
Conditions
Shortness of Breath Episode, Tachycardia, Bradycardia, Difficulty Breathing
Interventions
Not listed
Lead sponsor
Zoll Medical Corporation
Industry
Eligibility
18 Years and older
Enrollment
673 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
2
States / cities
Birmingham, Alabama • Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated May 12, 2024 · Synced Sep 8, 2026, 9:12 AM EDT
Completed Phase 1 Interventional

Pharmacokinetics/Pharmacodynamics (PK/PD) of Fluconazole in Children on Extracorporeal Membrane Oxygenation (ECMO)

NCT01169402
View directory record Official record
Conditions
Cardiopulmonary Arrest, Fungal Infection
Interventions
Fluconazole
Drug
Lead sponsor
Michael Cohen-Wolkowiez
Other
Eligibility
Up to 18 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 21, 2017 · Synced Sep 8, 2026, 9:12 AM EDT
Completed Phase 4 Interventional Results available

Etomidate Versus Ketamine for Emergency Endotracheal Intubation: a Prospective Randomized Clinical Trial

NCT02643381
View directory record Official record
Conditions
Cardiopulmonary Arrest, Respiratory Arrest
Interventions
Etomidate, Ketamine, Emergency Endotracheal Intubation, Mechanical Ventilation
Drug · Procedure · Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
801 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Dec 14, 2021 · Synced Sep 8, 2026, 9:12 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Optimizing Integration of CPR Feedback Technology With CPR Coaching for Cardiac Arrest

NCT03204162
View directory record Official record
Conditions
Cardiopulmonary Resuscitation
Interventions
CPR Coaching
Other
Lead sponsor
KidSIM Simulation Program
Network
Eligibility
Not listed
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
3
States / cities
Birmingham, Alabama • New York, New York • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 28, 2017 · Synced Sep 8, 2026, 9:12 AM EDT