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Showing 1–24 of 305 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Cardiovascular Surgical Procedure Clear all
Active, not recruiting Phase 2 Interventional Results available

Intramyocardial Injection of Autologous Umbilical Cord Blood Derived Mononuclear Cells During Surgical Repair of Hypoplastic Left Heart Syndrome

NCT03779711
View directory record Official record
Conditions
Hypoplastic Left Heart Syndrome
Interventions
Autologous (self) mononuclear cells derived from umbilical cord blood, Stage II Surgical repair
Biological · Procedure
Lead sponsor
Timothy J Nelson, MD, PhD
Other
Eligibility
Up to 12 Months
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
8
States / cities
Birmingham, Alabama • Los Angeles, California • Aurora, Colorado + 5 more
Source: ClinicalTrials.gov public record
Updated Jul 7, 2025 · Synced Jul 23, 2026, 2:18 PM EDT
Completed Not applicable Interventional Results available

The Effect of Natrox® Oxygen Wound Therapy on the Healing Rate of Chronic Diabetic Foot Ulcers

NCT03905863
View directory record Official record
Conditions
Diabetic Foot Ulcer, Surgical Wound
Interventions
Natrox® Oxygen Wound Therapy
Device
Lead sponsor
Inotec AMD Limited
Industry
Eligibility
18 Years and older
Enrollment
145 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
19
States / cities
Los Angeles, California • Miami, Florida • Miami Lakes, Florida + 15 more
Source: ClinicalTrials.gov public record
Updated Nov 21, 2021 · Synced Jul 23, 2026, 2:18 PM EDT
Completed No phase listed Observational

A Prospective Study of Patients With Hypoplastic Left Heart Syndrome (HLHS) Following Stage II Surgical Palliation

NCT01708863
View directory record Official record
Conditions
Hypoplastic Left Heart Syndrome
Interventions
Not listed
Lead sponsor
Timothy J Nelson, MD, PhD
Other
Eligibility
0 Months to 18 Months
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2020
U.S. locations
3
States / cities
Rochester, Minnesota • Oklahoma City, Oklahoma • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 4, 2020 · Synced Jul 23, 2026, 2:18 PM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Biomarker-Led Optimization of Successful Surgical Outcomes in Moyamoya

NCT06634004
View directory record Official record
Conditions
Moyamoya Disease
Interventions
BOLD MRI
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 69 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2030
U.S. locations
2
States / cities
Baltimore, Maryland • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Jul 23, 2026, 2:18 PM EDT
Completed No phase listed Observational

Short Term Outcomes From Minimally Invasive Surgery for the Treatment of Atrial Fibrillation

NCT00571597
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Not listed
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 85 Years
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 13, 2014 · Synced Jul 23, 2026, 2:18 PM EDT
Completed Not applicable Interventional Results available

A Comparison of Fractional Flow Reserve-Guided Percutaneous Coronary Intervention and Coronary Artery Bypass Graft Surgery in Patients With Multivessel Coronary Artery Disease

NCT02100722
View directory record Official record
Conditions
Coronary Disease, Coronary Stenosis
Interventions
FFR guided PCI, CABG, Resolute Integrity Stent, Resolute Onyx Stent
Procedure · Device
Lead sponsor
Stanford University
Other
Eligibility
21 Years and older
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2024
U.S. locations
13
States / cities
Palo Alto, California • Stanford, California • Decatur, Georgia + 9 more
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Jul 23, 2026, 2:18 PM EDT
Completed Phase 4 Interventional Results available

Prevention of Non-Surgical Bleeding by Management of HeartMate II Patients Without Antiplatelet Therapy

NCT02836652
View directory record Official record
Conditions
Heart Failure
Interventions
HeartMate II (HMII), Warfarin, acetylsalicylic acid (ASA) therapy
Device · Drug
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
50 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
33
States / cities
Birmingham, Alabama • Los Angeles, California • San Diego, California + 29 more
Source: ClinicalTrials.gov public record
Updated Jun 26, 2022 · Synced Jul 23, 2026, 2:18 PM EDT
Completed Not applicable Interventional Results available

Percutaneous Coronary Intervention (PCI) Outcomes in Community Versus Tertiary Settings

NCT01116882
View directory record Official record
Conditions
Coronary Artery Diseases
Interventions
PCI
Procedure
Lead sponsor
Baim Institute for Clinical Research
Other
Eligibility
18 Years and older
Enrollment
3,691 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
17
States / cities
Boston, Massachusetts • Brighton, Massachusetts • Brockton, Massachusetts + 8 more
Source: ClinicalTrials.gov public record
Updated Apr 6, 2015 · Synced Jul 23, 2026, 2:18 PM EDT
Completed Phase 2 Interventional Results available

Surgical Ablation Versus No Surgical Ablation for Patients With Atrial Fibrillation Undergoing Mitral Valve Surgery

NCT00903370
View directory record Official record
Conditions
Atrial Fibrillation, Mitral Valve Insufficiency, Mitral Valve Stenosis
Interventions
MVS, Ablation
Procedure · Device
Lead sponsor
Annetine Gelijns
Other
Eligibility
18 Years and older
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
18
States / cities
New Haven, Connecticut • Newark, Delaware • Atlanta, Georgia + 14 more
Source: ClinicalTrials.gov public record
Updated Feb 5, 2017 · Synced Jul 23, 2026, 2:18 PM EDT
Completed Phase 1 Interventional

A Dose Escalation and Safety Study of I5NP in Patients Undergoing Major Cardiovascular Surgery

NCT00554359
View directory record Official record
Conditions
Injury of Kidney, Acute Renal Failure
Interventions
I5NP (a small interfering RNA), placebo
Drug
Lead sponsor
Quark Pharmaceuticals
Industry
Eligibility
21 Years to 85 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
6
States / cities
Washington D.C., District of Columbia • Boston, Massachusetts • Cleveland, Ohio + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 22, 2011 · Synced Jul 23, 2026, 2:18 PM EDT
Completed Phase 3 Interventional Results available

Pivotal Trial of Dermagraft(R) to Treat Venous Leg Ulcers

NCT00909870
View directory record Official record
Conditions
Venous Leg Ulcer
Interventions
Dermagraft(R), Profore
Device
Lead sponsor
Organogenesis
Industry
Eligibility
18 Years and older
Enrollment
537 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
34
States / cities
Mobile, Alabama • Phoenix, Arizona • Tucson, Arizona + 28 more
Source: ClinicalTrials.gov public record
Updated Jun 17, 2018 · Synced Jul 23, 2026, 2:18 PM EDT
Not listed No phase listed Observational

Implanted Loop Recorder Post Atrial Fibrillation Ablation

NCT00915720
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Not listed
Lead sponsor
Thoracic & Cardiovascular Healthcare Foundation
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 19, 2011 · Synced Jul 23, 2026, 2:18 PM EDT
Completed Phase 3 Interventional

Biventricular Pacing In Patients With Left Ventricular Dysfunction After Cardiovascular Surgery

NCT00321295
View directory record Official record
Conditions
Cardiomyopathy, Heart Failure, Congestive, Thoracic Surgery
Interventions
Atrial synchronous bi-ventricular pacing
Device
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 4, 2011 · Synced Jul 23, 2026, 2:18 PM EDT
Completed No phase listed Observational

Dysphagia and VFMI in Cardiac Patients

NCT03768739
View directory record Official record
Conditions
Cardiac Disease
Interventions
Fiberoptic Endoscopic Evaluation of Swallowing
Procedure
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 90 Years
Enrollment
207 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
3
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 3, 2020 · Synced Jul 23, 2026, 2:18 PM EDT
Completed Phase 3 Interventional Results available

Comparison of Surgical and Medical Treatment for Congestive Heart Failure and Coronary Artery Disease

NCT00023595
View directory record Official record
Conditions
Cardiovascular Diseases, Coronary Disease, Heart Failure, Congestive, Heart Diseases
Interventions
CABG surgery plus MED, Active Medication Alone, CABG plus MED and SVR
Procedure · Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 100 Years
Enrollment
2,136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2015
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 18, 2019 · Synced Jul 23, 2026, 2:18 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Clinical Outcomes in Patients Treated With SternaLock Blu

NCT03709693
View directory record Official record
Conditions
Cardiac Surgical Procedures, Coronary Artery Disease, Heart Valve Diseases
Interventions
SternaLock Blu
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years to 100 Years
Enrollment
156 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
4
States / cities
Indianapolis, Indiana • Kansas City, Missouri • Memphis, Tennessee + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 22, 2021 · Synced Jul 23, 2026, 2:18 PM EDT
Completed No phase listed Observational

Total Knee Arthroplasty And Thromboembolism: A Comparison Between Two Surgical Techniques

NCT00755300
View directory record Official record
Conditions
Total Knee Replacement, Venous Thromboembolism
Interventions
Measurement of total thrombolic load
Procedure
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Aug 14, 2011 · Synced Jul 23, 2026, 2:18 PM EDT
Enrolling by invitation No phase listed Observational

Outcome of Patients With Severe Functional TR According to Medical, Transcatheter or Surgical Treatment

NCT05825898
View directory record Official record
Conditions
Tricuspid Regurgitation
Interventions
Surgery or Transcatheter tricuspid valve intervention
Procedure
Lead sponsor
Ottawa Heart Institute Research Corporation
Other
Eligibility
18 Years and older
Enrollment
3,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
4
States / cities
Rochester, Minnesota • New York, New York
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Jul 23, 2026, 2:18 PM EDT
Completed No phase listed Observational

The RESPOND Registry

NCT03286452
View directory record Official record
Conditions
Partial Thickness Wound, Pressure Ulcer, Venous Ulcer, Diabetic Ulcer, Surgical Wounds, Trauma Wounds, Draining Wounds, Chronic Vascular Ulcer
Interventions
PuraPly™ Antimicrobial Wound Matrix
Device
Lead sponsor
Organogenesis
Industry
Eligibility
18 Years and older
Enrollment
310 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
15
States / cities
Prescott Valley, Arizona • Jupiter, Florida • Miami, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Feb 26, 2019 · Synced Jul 23, 2026, 2:18 PM EDT
Completed Not applicable Interventional Results available

EO2 Oxygen Delivery To Study Success Rate of Surgically Closed Wounds

NCT03960463
View directory record Official record
Conditions
Surgical Wound, Diabetes, Amputation Wound, Incision Wound, Peripheral Arterial Disease, Breast Cancer, Diabetic Foot
Interventions
Transcu O2®
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 85 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 22, 2025 · Synced Jul 23, 2026, 2:18 PM EDT
Completed Phase 2 Interventional Results available

The Fibrin Pad Cardiovascular Study

NCT01681030
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
EVARREST™, Topical hemostat, Standard of Care
Biological · Other
Lead sponsor
Ethicon, Inc.
Industry
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
6
States / cities
Indianapolis, Indiana • Kansas City, Missouri • Camden, New Jersey + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 11, 2018 · Synced Jul 23, 2026, 2:18 PM EDT
Completed No phase listed Observational

HemoSonics - UTMB Cardiac Surgery Study

NCT03988465
View directory record Official record
Conditions
Blood Loss, Surgical
Interventions
Quantra System
Diagnostic Test
Lead sponsor
HemoSonics LLC
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 30, 2020 · Synced Jul 23, 2026, 2:18 PM EDT
Completed Phase 3 Interventional Results available

The Fibrin Pad CV Phase III Study

NCT02040428
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
EVARREST™ Fibrin Sealant Patch, Topical hemostat
Biological
Lead sponsor
Ethicon, Inc.
Industry
Eligibility
18 Years and older
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
9
States / cities
Atlanta, Georgia • Indianapolis, Indiana • Baltimore, Maryland + 6 more
Source: ClinicalTrials.gov public record
Updated Aug 14, 2017 · Synced Jul 23, 2026, 2:18 PM EDT
Completed Not applicable Interventional

ECG Leadwires: Disposable Versus Cleaned, Reusable

NCT01411553
View directory record Official record
Conditions
Critically Ill Patients, Cardiovascular Surgery Telemetry Patients
Interventions
Disposable ECG-LW
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
Not listed
Enrollment
4,056 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 22, 2016 · Synced Jul 23, 2026, 2:18 PM EDT