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Showing 1–24 of 113 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Carpal Tunnel Syndrome Clear all
Not listed No phase listed Observational Accepts healthy volunteers

Bilateral vs Unilateral CTR

NCT01961011
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
2
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 10, 2013 · Synced Sep 17, 2026, 3:21 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Treatment of Carpal Tunnel Syndrome With Dynamic Splinting

NCT00558116
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Dynamic splinting
Device
Lead sponsor
Advanced Centers for Orthopaedic Surgery and Sports Medicine
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Owings Mills, Maryland
Source: ClinicalTrials.gov public record
Updated May 12, 2008 · Synced Sep 17, 2026, 3:21 AM EDT
Completed Phase 2 Interventional Results available

A Study of Fisetin to Treat Carpal Tunnel Syndrome

NCT05416515
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Fisetin
Drug
Lead sponsor
Peter C. Amadio, M.D.
Other
Eligibility
21 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Sep 17, 2026, 3:21 AM EDT
Active, not recruiting No phase listed Observational

Registry of the Patient Experience for Carpal Tunnel Release

NCT06071468
View directory record Official record
Conditions
Carpal Tunnel Syndrome, CTS
Interventions
UltraGuideCTR (Device) with Ultrasound Guided Carpal Tunnel Release (CTR-US), Endocscopic CTR, Open CTR
Device · Procedure
Lead sponsor
Sonex Health, Inc.
Industry
Eligibility
18 Years and older
Enrollment
1,424 participants
Timeline
2024 – 2027
U.S. locations
33
States / cities
Foley, Alabama • Scottsdale, Arizona • Glastonbury, Connecticut + 30 more
Source: ClinicalTrials.gov public record
Updated Sep 13, 2026 · Synced Sep 17, 2026, 3:21 AM EDT
Enrolling by invitation Phase 2 Interventional

124I-Evuzamitide PET/CT Imaging In Patients With Lumbar Spinal Stenosis and Carpal Tunnel Syndrome

NCT06907849
View directory record Official record
Conditions
Lumbar Spinal Stenosis, Carpal Tunnel Syndrome (CTS), Cardiac Amyloidosis
Interventions
124I-evuzamitide
Drug
Lead sponsor
University of Tennessee Graduate School of Medicine
Other
Eligibility
60 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Sep 17, 2026, 3:21 AM EDT
Completed Phase 4 Interventional Results available

Preoperative Antibiotics for Carpal Tunnel Release Surgery

NCT03432858
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Vancomycin, Cefazolin, Saline Solution
Drug
Lead sponsor
WellSpan Health
Other
Eligibility
18 Years and older
Enrollment
184 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
York, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 9, 2021 · Synced Sep 17, 2026, 3:21 AM EDT
Suspended Early Phase 1 Interventional Accepts healthy volunteers

Lipografting Versus Steroid Injections for Treatment of Carpal Tunnel Syndrome

NCT03722303
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Fat Injection, Steroid Injection
Other · Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 28, 2025 · Synced Sep 17, 2026, 3:21 AM EDT
Terminated No phase listed Observational

Effect of Celliant Materials on Pain and Blood Oxygenation in Subjects With Chronic Elbow and Wrist Pain

NCT00688220
View directory record Official record
Conditions
Chronic Wrist Pain, Chronic Elbow Pain
Interventions
Not listed
Lead sponsor
Southern California Institute for Research and Education
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Long Beach, California
Source: ClinicalTrials.gov public record
Updated Jun 3, 2010 · Synced Sep 17, 2026, 3:21 AM EDT
Completed No phase listed Observational

Very Early Outcomes in Endoscopic Versus Open Carpal Tunnel Release

NCT07364604
View directory record Official record
Conditions
Carpal Tunnel Syndrome (CTS)
Interventions
Carpal Tunnel Release
Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Sep 17, 2026, 3:21 AM EDT
Not listed No phase listed Observational

Post-Operative Splinting After Short-Incision Carpal Tunnel Release: a Prospective Study

NCT01897272
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Splinting
Behavioral
Lead sponsor
Christine M. Kleinert Institute for Hand and Microsurgery
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
2
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 24, 2018 · Synced Sep 17, 2026, 3:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Relationship Between Age and Carpal Tunnel Size

NCT03294733
View directory record Official record
Conditions
Carpal Tunnel
Interventions
Ultrasound
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 25, 2020 · Synced Sep 17, 2026, 3:21 AM EDT
Completed Phase 2 Interventional

Open-Label Study Evaluating Synera® in the Treatment of Patients With Carpal Tunnel Syndrome

NCT00991068
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Synera (lidocaine 70 mg and tetracaine 70 mg) topical patch
Drug
Lead sponsor
ZARS Pharma Inc.
Industry
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Mar 15, 2012 · Synced Sep 17, 2026, 3:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Decision Making in Hypothetical Carpal Tunnel Syndrome

NCT03730376
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Cost Information
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
488 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Mar 18, 2020 · Synced Sep 17, 2026, 3:21 AM EDT
Terminated Not applicable Interventional

Comparative Study of Two Incision vs. Mini Open Carpal Tunnel Release

NCT05325567
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Mini open incision CTR
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 17, 2023 · Synced Sep 17, 2026, 3:21 AM EDT
Completed Not applicable Interventional

Carpal Tunnel Release With Risk Factors for Amyloidosis

NCT05793320
View directory record Official record
Conditions
Amyloidosis
Interventions
Carpal Tunnel Release Surgery
Procedure
Lead sponsor
Henry Ford Health System
Other
Eligibility
50 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 17, 2026, 3:21 AM EDT
Recruiting Not applicable Interventional

Effect of Cooling Therapy for Post-Operative Pain in Open Carpal Tunnel Release

NCT05783245
View directory record Official record
Conditions
Carpal Tunnel Syndrome, Perioperative/Postoperative Complications
Interventions
Polarcare Machine, Standard of care ice therapy
Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Sep 17, 2026, 3:21 AM EDT
Completed No phase listed Observational

Typing Proficiency Following Carpal Tunnel Release

NCT01853969
View directory record Official record
Conditions
Carpal Tunnel Release
Interventions
Typing assessment
Other
Lead sponsor
Vanderbilt University
Other
Eligibility
20 Years to 70 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 16, 2015 · Synced Sep 17, 2026, 3:21 AM EDT
Completed Phase 2 Interventional Results available

BOTOX® (Onabotulinumtoxin A) Injection(s) as a Treatment for Carpal Tunnel Syndrome

NCT02070302
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Botulinum Toxin Type A, Placebo
Drug
Lead sponsor
Benjamin Sucher
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Sep 26, 2017 · Synced Sep 17, 2026, 3:21 AM EDT
Completed Not applicable Interventional

COMET-AOA: Median Nerve Stiffness in Mild-Moderate CTS With OMT & Conservative Therapy

NCT06150443
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Osteopathic manipulative treatment (OMT), Conservative treatment
Other
Lead sponsor
Kettering Health Network
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Sep 17, 2026, 3:21 AM EDT
Terminated Phase 4 Interventional Results available

Patient Satisfaction With Pain Relief After Ambulatory Hand Surgery

NCT01588158
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Acetaminophen, Vicodin
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 13, 2017 · Synced Sep 17, 2026, 3:21 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Avazzia HVPC Bio-Electrical Stimulation Technology (BEST™) Microcurrent CTS RCT

NCT04271319
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
BEST™ HVPC microcurrent electrical stimulation PRO-SPORT Ultra® Device, Sham PRO-SPORT Ultra® Device
Device
Lead sponsor
Avazzia, Inc
Industry
Eligibility
18 Years to 70 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 26, 2021 · Synced Sep 17, 2026, 3:21 AM EDT
Not yet recruiting Not applicable Interventional

Understanding Patient Preferences When Deciding on a Voluntary Musculoskeletal Test

NCT07158892
View directory record Official record
Conditions
Non-traumatic Musculoskeletal Conditions, Carpal Tunnel Syndrome (CTS), Lateral Epicondylitis, Osteoarthritis, Trigger Digit, Dupuytren Contracture, Rotator Cuff Tendinopathy, De Quervain Disease
Interventions
Diagnostic Advance Care Planning Discussion, Informational Statement Only
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Sep 7, 2025 · Synced Sep 17, 2026, 3:21 AM EDT
Terminated Not applicable Interventional

The Effect of Surgical Incision Size on Carpal Tunnel Surgery

NCT00435071
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Carpal tunnel release surgery
Procedure
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 17, 2011 · Synced Sep 17, 2026, 3:21 AM EDT
Enrolling by invitation Not applicable Interventional

Assessment of Carpal Tunnel Syndrome by Shearwave Elastography

NCT04804293
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
FDA approved ultrasound system with shear wave elastography capability
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 100 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
2
States / cities
Scottsdale, Arizona • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Sep 17, 2026, 3:21 AM EDT