Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 6, 2026, 9:08 AM EDT

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Showing 1–24 of 44 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Cataract
Interventions
Acrysof Natural ReSTOR SN60D3, Acrysof Natural Monofocal SN60AT
Device
Lead sponsor
Alcon Research
Industry
Eligibility
50 Years to 75 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Fort Worth, Texas
Conditions
Cataract
Interventions
Tecnis Multifocal 1-Piece IOL
Device
Lead sponsor
Dell Laser Consultants
Other
Eligibility
21 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Austin, Texas
Conditions
Cataract
Interventions
AcrySof® ReSTOR® Aspheric IOL
Device
Lead sponsor
Alcon Research
Industry
Eligibility
21 Years and older
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2007
U.S. locations
1
States / cities
Fort Worth, Texas
Conditions
Cataract
Interventions
Levofloxacin Ocular Implant, Control
Drug
Lead sponsor
PolyActiva Pty Ltd
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
2
States / cities
St Louis, Missouri • Ladson, South Carolina
Conditions
Bilateral Cataract
Interventions
ISBCS, DSBCS
Procedure
Lead sponsor
Sloan W. Rush, MD
Other
Eligibility
30 Years to 100 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2022
U.S. locations
1
States / cities
Amarillo, Texas
Conditions
Cataracts
Interventions
AcrySof ReSTOR Aspheric IOL
Device
Lead sponsor
Alcon Research
Industry
Eligibility
50 Years to 75 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2008
U.S. locations
1
States / cities
Fort Worth, Texas
Completed Phase 4 Interventional Results available

Presbyopia-Correcting Intraocular Lenses (IOLs)

NCT00963560
Conditions
Cataract
Interventions
ReSTOR +3, Crystalens HD, Crystalens AO
Device
Lead sponsor
Alcon Research
Industry
Eligibility
21 Years and older
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2009
U.S. locations
1
States / cities
Fort Worth, Texas
Conditions
Patient Preference
Interventions
Dexamethasone, Standard of care surgery
Drug · Other
Lead sponsor
Ophthalmic Consultants of Long Island
Other
Eligibility
22 Years to 100 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Garden City, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Vision After Vivity IOL Implantation With a Target of Slight Myopia in the Non-dominant Eye

NCT04482439
Conditions
Cataract
Interventions
Vivity Extended Depth of Focus intraocular lens (IOL)
Device
Lead sponsor
Newsom Eye & Laser Center
Other
Eligibility
40 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Sebring, Florida
Completed No phase listed Observational Results available

Cerebrotendinous Xanthomatosis (CTX) Prevalence Study

NCT02638220
Conditions
Cerebrotendinous Xanthomatosis (CTX)
Interventions
Not listed
Lead sponsor
Travere Therapeutics, Inc.
Industry
Eligibility
2 Years to 21 Years
Enrollment
442 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
44
States / cities
Birmingham, Alabama • La Jolla, California • Los Angeles, California + 38 more
Completed No phase listed Observational Accepts healthy volunteers

Visual Performance of Bilateral AcrySof ReSTOR Aspheric +4

NCT01215045
Conditions
Cataract
Interventions
AcrySof ReSTOR Aspheric +4
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years to 70 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Fort Worth, Texas
Completed No phase listed Observational Results available

Symfony/Synergy IOL Combination Outcomes

NCT05604781
Conditions
Bilateral Cataract, Presbyopia
Interventions
Symfony & Synergy IOL combination
Device
Lead sponsor
Center For Sight
Other
Eligibility
50 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
2
States / cities
Venice, Florida • Mt. Pleasant, South Carolina
Conditions
Correction Vision Surgery, Cataract Surgery
Interventions
cataract surgery
Procedure
Lead sponsor
Utah Eye Centers
Other
Eligibility
Not listed
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Ogden, Utah
Conditions
Cataract
Interventions
AcrySof ReSTOR Aspheric IOL model SN6AD1
Device
Lead sponsor
Alcon Research
Industry
Eligibility
21 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Fort Worth, Texas
Conditions
Nuclear Sclerosis of the Lens, Phacoemulsification Cataract Surgery, Cataract Bilateral
Interventions
Cataract extraction with phacoemulsification comparing two systems
Device
Lead sponsor
Nicole Fram M.D.
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Completed Not applicable Interventional Results available

Tecnis ZLB00 & Symfony Intraocular Lens Combination Outcomes

NCT03771274
Conditions
Cataract Bilateral, Presbyopia
Interventions
Tecnis ZLB00 & Symfony IOL
Device
Lead sponsor
Carolina Eyecare Physicians, LLC
Other
Eligibility
40 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Mt. Pleasant, South Carolina
Conditions
Cataract
Interventions
Clareon PanOptix, Clareon PanOptix PRO, Mix-and-Match PanOptix/Vivity
Device · Drug
Lead sponsor
Berkeley Eye Center
Other
Eligibility
40 Years and older
Enrollment
320 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
2
States / cities
Plymouth Meeting, Pennsylvania • Houston, Texas
Conditions
Cataract
Interventions
Crystalens AO, SoftPort LI61AO
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
40 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Irvine, California
Conditions
Cataract
Interventions
Panoptix Toric
Device
Lead sponsor
Eye Center of North Florida
Other
Eligibility
40 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Panama City, Florida
Conditions
Cataract
Interventions
Model SN60WF, Model MA60AC
Device
Lead sponsor
Alcon Research
Industry
Eligibility
50 Years and older
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Fort Worth, Texas
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cataract Monitored Anesthesia Care (MAC) Feasibility Pilot Study

NCT06506669
Conditions
Cataract, Bilateral Senile Cataract, Anesthesia, Patient Satisfaction
Interventions
Oral sedation, Placebo
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
60 Years and older
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Francisco, California
Conditions
Cataract
Interventions
Clareon TruPlus, Clareon monofocal
Device
Lead sponsor
Berkeley Eye Center
Other
Eligibility
22 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Sugar Land, Texas
Conditions
Cataract
Interventions
PureSee IOL
Device
Lead sponsor
Vance Thompson Vision
Other
Eligibility
40 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Sioux Falls, South Dakota