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ClinicalTrials.gov public records Last synced Oct 30, 2026, 3:01 PM EDT

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Showing 1–24 of 183 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Catheter Ablation Clear all
Completed Not applicable Interventional

Radiofrequency Catheter Ablation for Chronic Atrial Fibrillation

NCT00272636
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Radiofrequency catheter ablation, Amiodarone and cardioversion
Procedure · Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 70 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 3, 2015 · Synced Oct 30, 2026, 3:01 PM EDT
Recruiting Phase 1Phase 2 Interventional

Minimally Invasive Esophagectomy Pain Control Trial

NCT05906134
View directory record Official record
Conditions
Postoperative Pain, Acute, Postoperative Complications
Interventions
Local intercostal nerve block, Cryo-analgesia and intercostal nerve block, Serratus plane catheter blocks and intercostal nerve blocks, Thoracic epidural catheter
Procedure
Lead sponsor
Swedish Medical Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 23, 2025 · Synced Oct 30, 2026, 3:01 PM EDT
Suspended Phase 3 Interventional

High Intensity Focused Ultrasound (HIFU) Ablation System Study

NCT00392106
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
propafenone, flecainide, dofetilide, sotolol, Pulmonary vein ablation, Amiodarone
Drug · Device
Lead sponsor
ProRhythm, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
20
States / cities
Fullerton, California • Los Angeles, California • Atlanta, Georgia + 16 more
Source: ClinicalTrials.gov public record
Updated Jun 17, 2008 · Synced Oct 30, 2026, 3:01 PM EDT
Terminated Not applicable Interventional Results available

Atrial Pressure Electrophysiology Pilot Study

NCT01845974
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
ThermoCool® SF NAV Catheter, ThermoCool® catheter
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Park Ridge, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 3, 2024 · Synced Oct 30, 2026, 3:01 PM EDT
Completed Not applicable Interventional Results available

Tailored vs. Anatomical Ablation Strategy for Persistent Atrial Fibrillation

NCT04702451
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Dispersion ablation + PVI, VX1, PVI
Procedure · Device
Lead sponsor
Volta Medical
Industry
Eligibility
18 Years and older
Enrollment
377 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
8
States / cities
Birmingham, Alabama • Jacksonville, Florida • St Louis, Missouri + 5 more
Source: ClinicalTrials.gov public record
Updated Sep 12, 2025 · Synced Oct 30, 2026, 3:01 PM EDT
Not listed Not applicable Interventional

Impact of Anxiety on Cardiac Substrate Modification in Women With Atrial Fibrillation Undergoing Catheter Ablation

NCT02547584
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Catheter ablation
Procedure
Lead sponsor
Texas Cardiac Arrhythmia Research Foundation
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Sep 10, 2019 · Synced Oct 30, 2026, 3:01 PM EDT
Terminated Not applicable Interventional Results available

Therapy Cool Path Ablate VT

NCT00925522
View directory record Official record
Conditions
Ischemic Ventricular Tachycardia
Interventions
Therapy Cool Path Duo Cardiac Ablation System
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
5
States / cities
Birmingham, Alabama • Maywood, Illinois • Indianapolis, Indiana + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 17, 2019 · Synced Oct 30, 2026, 3:01 PM EDT
Recruiting Not applicable Interventional

Post-ablation Alcohol Impacts Arrhythmia Recurrence, Quality of Life and Cognition in AF

NCT05510167
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Study arm
Behavioral
Lead sponsor
Texas Cardiac Arrhythmia Research Foundation
Other
Eligibility
18 Years to 85 Years
Enrollment
184 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 30, 2026, 3:01 PM EDT
Active, not recruiting Not applicable Interventional

Pulsed-Field Ablation With/Without Electrogram Mapping

NCT07541989
View directory record Official record
Conditions
Non-paroxysmal Atrial Fibrillation
Interventions
PFA-based PVI+PWI plus adjunctive ablation guided by Electrogram Mapping of Key Substrates, PFA-based PVI+PWI alone
Procedure
Lead sponsor
Xu Liu
Other
Eligibility
18 Years to 80 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Oct 30, 2026, 3:01 PM EDT
Completed Phase 4 Interventional

A Comparison of Antiarrhythmic Drug Therapy and Radio Frequency Catheter Ablation in Patients With Paroxysmal Atrial Fibrillation

NCT00540787
View directory record Official record
Conditions
Paroxysmal Atrial Fibrillation
Interventions
Radiofrequency ablation, antiarrhythmic drugs, Amiodarone, flecainide, propafenone, quinidine, dofetilide, sotalol, cibenzoline, beta blocking and calcium channel blocking agents and antiarrhythmic drugs, ThermoCool Radiofrequency Catheter
Device · Drug
Lead sponsor
Biosense Webster, Inc.
Industry
Eligibility
18 Years and older
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
3
States / cities
Birmingham, Alabama • Boston, Massachusetts • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 28, 2025 · Synced Oct 30, 2026, 3:01 PM EDT
Suspended Not applicable Interventional

Half-normal Saline in Idiopathic Left Ventricular Outflow Tract Arrhythmias Ablation

NCT03502499
View directory record Official record
Conditions
Ventricular Arrythmia
Interventions
Half-normal saline, Normal saline
Drug
Lead sponsor
Texas Cardiac Arrhythmia Research Foundation
Other
Eligibility
18 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
2
States / cities
Aurora, Colorado • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 11, 2022 · Synced Oct 30, 2026, 3:01 PM EDT
Terminated No phase listed Observational

Release of Acetylcholine From the Ganglionated Plexus During the Thaw Phase of Cryoballon Pulmonary Vein Ablation (GP RESPONSE Study)

NCT03636100
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Cryoballoon ablation
Device
Lead sponsor
Saint Luke's Health System
Other
Eligibility
18 Years to 80 Years
Enrollment
7 participants
Timeline
2018 – 2019
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 19, 2021 · Synced Oct 30, 2026, 3:01 PM EDT
Completed No phase listed Observational

Trancutaneous Monitoring to Avoid Hypercapnea During Complex Catheter Ablations

NCT01815034
View directory record Official record
Conditions
Hypercapnia
Interventions
Not listed
Lead sponsor
The Cleveland Clinic
Other
Eligibility
Not listed
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 19, 2014 · Synced Oct 30, 2026, 3:01 PM EDT
Terminated Not applicable Interventional

Safety and Efficacy Study of The Combined Ablation Procedure To Treat Longstanding Persistent Atrial Fibrillation

NCT01103661
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Numeris®-AF Guided Coagulation System with VisiTrax®
Device
Lead sponsor
nContact Surgical Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
4
States / cities
Indianapolis, Indiana • Memphis, Tennessee • Austin, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 3, 2014 · Synced Oct 30, 2026, 3:01 PM EDT
Completed Not applicable Interventional Results available

Clinical Evaluation of the Blazer® Open-Irrigated Catheter for Treatment of Type 1 Atrial Flutter

NCT01253200
View directory record Official record
Conditions
Atrial Flutter
Interventions
Blazer® Open-Irrigated Ablation Catheter, Control Catheter
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
302 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
26
States / cities
Birmingham, Alabama • Fullerton, California • Sacramento, California + 21 more
Source: ClinicalTrials.gov public record
Updated Mar 19, 2018 · Synced Oct 30, 2026, 3:01 PM EDT
Completed Phase 4 Interventional Results available

Corticosteroid Pulse After Ablation

NCT00807586
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Solumedrol, Placebo
Drug
Lead sponsor
Minneapolis Heart Institute Foundation
Other
Eligibility
18 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 20, 2019 · Synced Oct 30, 2026, 3:01 PM EDT
Completed Not applicable Interventional Results available

Esophageal Cooling in Radiofrequency Cardiac Ablation

NCT03481023
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
EnsoETM, Conventional Care
Device · Procedure
Lead sponsor
Riverside Medical Center
Other
Eligibility
18 Years to 90 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Kankakee, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 28, 2024 · Synced Oct 30, 2026, 3:01 PM EDT
Completed Phase 4 Interventional Results available

Metformin as an Adjunctive Therapy to Catheter Ablation in Atrial Fibrillation

NCT04625946
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Metformin, Recommendations for lifestyle modification., AliveCor
Drug · Behavioral · Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 30, 2026, 3:01 PM EDT
Withdrawn Phase 4 Interventional

Comparison of Reverse Remodeling and PVI Versus CFAE and/or Linear Lesions and PVI for Persistent AF

NCT01877473
View directory record Official record
Conditions
Persistent Atrial Fibrillation
Interventions
Ablation
Procedure
Lead sponsor
Valley Health System
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Ridgewood, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 17, 2014 · Synced Oct 30, 2026, 3:01 PM EDT
Terminated Not applicable Interventional

Comparison of PVI Plus Catheter Ablation or PVI Alone for the Treatment of AFib for Patients With Paroxysmal Atrial Fibrillation

NCT03115554
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
PVI Plus Catheter Ablation, PVI Alone
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 3, 2024 · Synced Oct 30, 2026, 3:01 PM EDT
Completed Not applicable Interventional Results available

Evaluation of the CIRCA Monitoring System in Prevention of Esophageal Lesions Following RFCA

NCT02467166
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Circa™ Probe
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 2, 2021 · Synced Oct 30, 2026, 3:01 PM EDT
Completed Phase 3 Interventional Results available

First Line Radiofrequency Ablation Versus Antiarrhythmic Drugs for Atrial Fibrillation Treatment (The RAAFT Study)

NCT00392054
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Pulmonary Vein Isolation performed by Catheter Ablation, Conventional Antiarrhythmic Drug Therapy
Procedure · Drug
Lead sponsor
Population Health Research Institute
Other
Eligibility
19 Years to 75 Years
Enrollment
127 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
2
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jan 31, 2020 · Synced Oct 30, 2026, 3:01 PM EDT
Recruiting Not applicable Interventional

Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)

NCT06703489
View directory record Official record
Conditions
Ventricular Tachycardia (VT)
Interventions
Sphere-9 Catheter with the Affera Mapping and Ablation System
Device
Lead sponsor
Medtronic Cardiac Ablation Solutions
Industry
Eligibility
18 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
6
States / cities
Boston, Massachusetts • New York, New York • Cleveland, Ohio + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Oct 30, 2026, 3:01 PM EDT
Completed Phase 3 Interventional

Role of Coumadin in Preventing Thromboembolism in Atrial Fibrillation (AF) Patients Undergoing Catheter Ablation

NCT01006876
View directory record Official record
Conditions
Thromboembolism
Interventions
Coumadin
Drug
Lead sponsor
Texas Cardiac Arrhythmia Research Foundation
Other
Eligibility
18 Years to 75 Years
Enrollment
1,584 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated May 20, 2015 · Synced Oct 30, 2026, 3:01 PM EDT