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ClinicalTrials.gov public records Last synced May 21, 2026, 8:11 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 37 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Central Nervous System Sensitization Clear all
Not listed Not applicable Interventional
View directory record Official record
Conditions
Chronic Pain
Interventions
Body scan meditation
Procedure
Lead sponsor
Therapeutic Neuroscience Research Group
Network
Eligibility
18 Years to 80 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 10, 2022 · Synced May 21, 2026, 8:11 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Cystitis, Interstitial, Dysmenorrhea, Migraine Disorders, Pelvic Pain, Endometriosis, Visceral Pain, Chronic Pain
Interventions
cyclic microgestin 1/20, continuous microgestin 1/20
Drug
Lead sponsor
Endeavor Health
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
353 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2021
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 17, 2023 · Synced May 21, 2026, 8:11 PM EDT
Completed Phase 2 Interventional
View directory record Official record
Conditions
Pain
Interventions
Rofecoxib
Drug
Lead sponsor
National Institute of Dental and Craniofacial Research (NIDCR)
NIH
Eligibility
Not listed
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2003
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced May 21, 2026, 8:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Ketamine, Normal saline
Drug · Other
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 90 Years
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Oct 17, 2018 · Synced May 21, 2026, 8:11 PM EDT
Terminated Phase 4 Interventional Results available
View directory record Official record
Conditions
Low Back Pain
Interventions
Vertis Percutaneous Neuromodulation Therapy (PNT), Transcutaneous Electrical Nerve Stimulation (TENS)
Device
Lead sponsor
RS Medical
Industry
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
8
States / cities
La Jolla, California • Atlanta, Georgia • Eugene, Oregon + 5 more
Source: ClinicalTrials.gov public record
Updated May 31, 2009 · Synced May 21, 2026, 8:11 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Pain
Interventions
Remote Ischemic Preconditioning, Capsaicin, UV-B
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 55 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 9, 2018 · Synced May 21, 2026, 8:11 PM EDT
Not yet recruiting Not applicable Interventional
View directory record Official record
Conditions
Widspread Chronic Pain, Fibromyalgia
Interventions
Vagal nerve stimulation through deep exhalation exercise, Vagal nerve stimulation through ear electrical stimulation, No intervention (observational study)
Other
Lead sponsor
University of North Georgia
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Dahlonega, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 22, 2025 · Synced May 21, 2026, 8:11 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Dysmenorrhea, Menstrual Pain, Non-steroidal Anti-inflammatory Drug
Interventions
Sodium Naproxen, Placebo
Drug
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced May 21, 2026, 8:11 PM EDT
Withdrawn Not applicable Interventional
View directory record Official record
Conditions
Chronic Pain
Interventions
Immersive Virtual Reality
Device
Lead sponsor
Tufts University
Other
Eligibility
25 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 27, 2023 · Synced May 21, 2026, 8:11 PM EDT
Withdrawn Phase 4 Interventional
View directory record Official record
Conditions
Endometriosis, Chronic Pelvic Pain
Interventions
ketamine
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 89 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 10, 2026 · Synced May 21, 2026, 8:11 PM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Myofascial Pain, Physical Therapy
Interventions
Physical Therapy
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced May 21, 2026, 8:11 PM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Active music-based intervention
Procedure
Lead sponsor
Sharon Wang-Price
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Denton, Texas
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced May 21, 2026, 8:11 PM EDT
Not listed Not applicable Interventional
View directory record Official record
Conditions
Central Sensitization, Low Back Pain, Pain Catastrophizing
Interventions
Pain Verbalization Repression Rules
Behavioral
Lead sponsor
Keystone Rehabilitation Systems
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 11, 2012 · Synced May 21, 2026, 8:11 PM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Chronic Pain, Central Sensitisation, Headache
Interventions
Web-based CBT (Web-MAP)
Behavioral
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
12 Years to 17 Years
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 17, 2022 · Synced May 21, 2026, 8:11 PM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Chronic Pain, Adults 21 and Older, Multiple Chronic Overlapping Pain Conditions, Hypersensitivity
Interventions
High Intensity Quell, Low Intensity Quell
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 99 Years
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 18, 2025 · Synced May 21, 2026, 8:11 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Insomnia, Fibromyalgia
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-I), Cognitive Behavioral Therapy for Pain (CBT-P)
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Dec 3, 2013 · Synced May 21, 2026, 8:11 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
New Daily Persistent Headache (NDPH)
Interventions
Naltrexone HCl (Bulk) Powder
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
10 Years to 17 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 5, 2022 · Synced May 21, 2026, 8:11 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Pain, Postoperative, Total Knee Arthroplasty
Interventions
Duloxetine, Placebos
Drug
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
241 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced May 21, 2026, 8:11 PM EDT
Completed Phase 2 Interventional
View directory record Official record
Conditions
Pain, Tooth Extraction
Interventions
Rofecoxib and Bupivacaine
Drug
Lead sponsor
National Institute of Dental and Craniofacial Research (NIDCR)
NIH
Eligibility
Not listed
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2004
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced May 21, 2026, 8:11 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Aerobic exercise program
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
21 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Sep 26, 2019 · Synced May 21, 2026, 8:11 PM EDT
Completed No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Central Nervous System Sensitization
Interventions
Posturography Evaluation, Central Sensitization Inventory
Diagnostic Test · Other
Lead sponsor
Caps Research Network
Other
Eligibility
18 Years to 65 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Marietta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 3, 2021 · Synced May 21, 2026, 8:11 PM EDT
Completed Phase 1 Interventional
View directory record Official record
Conditions
Fibromyalgia
Interventions
Milnacipran
Drug
Lead sponsor
University of Florida
Other
Eligibility
30 Years to 65 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 30, 2014 · Synced May 21, 2026, 8:11 PM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Low Back Pain, Knee Osteoarthritis, Neck Pain
Interventions
Standard Physical Therapy care
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
77 participants
Timeline
2022 – 2024
U.S. locations
1
States / cities
Shawnee Mission, Kansas
Source: ClinicalTrials.gov public record
Updated May 19, 2025 · Synced May 21, 2026, 8:11 PM EDT
Terminated Not applicable Interventional
View directory record Official record
Conditions
Chronic Pain, Fibromyalgia, Central Sensitisation
Interventions
BreathAware for Pain Management
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
30 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 26, 2020 · Synced May 21, 2026, 8:11 PM EDT