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Showing 1–24 of 63 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Cervical Ripening Clear all
Completed Phase 2 Interventional

A Randomized, Control Trial for Preinduction Cervical Ripening

NCT00393731
View directory record Official record
Conditions
Labor, Induced
Interventions
Misoprostol, oxytocin
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
Female only
Enrollment
540 participants
Timeline
2004 – 2007
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 15, 2008 · Synced Jul 23, 2026, 12:36 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Study of the Effectiveness of Cervical Ripening Balloon With and Without Oxytocin

NCT03138252
View directory record Official record
Conditions
Cervical Ripening, Induction of Labor, Multiparity
Interventions
Oxytocin
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 3, 2022 · Synced Jul 23, 2026, 12:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Foley Balloon Study for Cervical Ripening - Cost Comparison Between Outpatient and Inpatient Cervical Ripening

NCT05506631
View directory record Official record
Conditions
Pregnancy Outcome
Interventions
Outpatient Foley balloon placement, Inpatient Foley Balloon placement
Procedure
Lead sponsor
Lehigh Valley Hospital
Other
Eligibility
18 Years to 39 Years · Female only
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Allentown, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 30, 2025 · Synced Jul 23, 2026, 12:36 PM EDT
Completed Not applicable Interventional

Outpatient Foley For Starting Induction of Labor at Term in Nulliparous Women

NCT03472937
View directory record Official record
Conditions
Pregnancy Related
Interventions
Transcervical Foley catheter placement for cervical ripening
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older · Female only
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 5, 2020 · Synced Jul 23, 2026, 12:36 PM EDT
Not yet recruiting Not applicable Interventional

Ripening Approaches for Prompt Induction and Delivery - Sequential Versus Concurrent Dilapan-S and Misoprostol to Achieve Vaginal Delivery (RAPID-DS)

NCT07717502
View directory record Official record
Conditions
Nulliparous Women Who Scheduled for Labor Induction, Pregnancy
Interventions
Sequential Cervical Ripening, Inpatient Combined Cervical Ripening
Combination Product
Lead sponsor
Ochsner Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Jul 23, 2026, 12:36 PM EDT
Terminated Not applicable Interventional Results available

Cervical Ripening in Postmenopausal Women

NCT02534883
View directory record Official record
Conditions
Stenosis of Cervix
Interventions
Misoprostol, Placebo
Drug
Lead sponsor
St. Louis University
Other
Eligibility
45 Years to 85 Years · Female only
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 11, 2018 · Synced Jul 23, 2026, 12:36 PM EDT
Recruiting Not applicable Interventional

Cervical Ripening Balloons for Same-Day Cervical Prep

NCT06964373
View directory record Official record
Conditions
Dilation and Evacuation
Interventions
Cervical Ripening Balloon, Osmotic Dilators
Device
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older · Female only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Jul 23, 2026, 12:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Combined Agent Randomized Trial of Induction of Labor

NCT00504465
View directory record Official record
Conditions
Labor Induction, Cervical Ripening
Interventions
dinoprostone
Drug
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 45 Years
Enrollment
210 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2007
U.S. locations
3
States / cities
Brooklyn, New York • Flushing, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 19, 2007 · Synced Jul 23, 2026, 12:36 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Comparison of Misoprostol Ripening Efficacy With Dilapan

NCT03670836
View directory record Official record
Conditions
Labor Onset and Length Abnormalities, Induced; Birth
Interventions
Dilapan, Misoprostol
Device · Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Female only
Enrollment
307 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
2
States / cities
New York, New York • Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 18, 2024 · Synced Jul 23, 2026, 12:36 PM EDT
Terminated Not applicable Interventional Results available

Prehospital Cervical Ripening Before Induction and the Maternal Experience

NCT01641601
View directory record Official record
Conditions
Labor, Induced, Cervical Ripening
Interventions
Outpatient transcervical Foley balloon
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
15 Years to 50 Years · Female only
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 4, 2020 · Synced Jul 23, 2026, 12:36 PM EDT
Completed No phase listed Observational

Outpatient Cervical Ripening

NCT04041687
View directory record Official record
Conditions
Pregnancy
Interventions
Not listed
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
Female only
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 29, 2024 · Synced Jul 23, 2026, 12:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Tension Versus Tension- Free Foley Balloon for Cervical Ripening

NCT05404776
View directory record Official record
Conditions
Induced Vaginal Delivery
Interventions
Placement of Foley balloon for cervical ripening with tension., Placement of Foley balloon for cervical ripening without tension.
Other
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
279 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 5, 2025 · Synced Jul 23, 2026, 12:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparing Outpatient to Inpatient Cervical Ripening Using Dilapan-S®

NCT03665688
View directory record Official record
Conditions
Labor, Induced, Cervix Uteri-Diseases
Interventions
Outpatient Dilapan-S, Inpatient Dilapan-S
Device
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
338 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
2
States / cities
New York, New York • Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 26, 2023 · Synced Jul 23, 2026, 12:36 PM EDT
Completed No phase listed Observational

Labor Induction With Oral Versus Vaginal Misoprostol

NCT04755218
View directory record Official record
Conditions
Pregnancy, Labor, Induced
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
10 Years and older · Female only
Enrollment
2,546 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Apr 4, 2024 · Synced Jul 23, 2026, 12:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cervical Foley Plus Vaginal Misoprostol for Labor Induction

NCT01279343
View directory record Official record
Conditions
Induction of Labor
Interventions
Foley bulb
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
16 Years to 45 Years · Female only
Enrollment
123 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 2, 2019 · Synced Jul 23, 2026, 12:36 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Cervical Ripening as an Outpatient Method Using the Foley (COMFORT)

NCT05759988
View directory record Official record
Conditions
Induction of Labor Affected Fetus / Newborn
Interventions
Outpatient Foley catheter
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
2,300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
6
States / cities
Newark, Delaware • Plainsboro, New Jersey • Philadelphia, Pennsylvania + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 1, 2026 · Synced Jul 23, 2026, 12:36 PM EDT
Withdrawn Phase 2 Interventional Accepts healthy volunteers

Pharmacokinetics and Safety of the 100 Mcg Misoprostol Vaginal Insert (MVI 100)

NCT00528255
View directory record Official record
Conditions
Cervical Ripening, Induction of Labor
Interventions
Misoprostol Vaginal Insert (MVI 100)
Drug
Lead sponsor
Ferring Pharmaceuticals
Industry
Eligibility
18 Years and older · Female only
Healthy volunteers
Accepts healthy volunteers
U.S. locations
6
States / cities
Phoenix, Arizona • Long Beach, California • Orange, California + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 17, 2012 · Synced Jul 23, 2026, 12:36 PM EDT
Completed Not applicable Interventional Results available

Outpatient Foley For Starting Induction of Labor at TErm

NCT02756689
View directory record Official record
Conditions
Pregnancy
Interventions
Inpatient cervical ripening, Outpatient cervical ripening
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older · Female only
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 8, 2019 · Synced Jul 23, 2026, 12:36 PM EDT
Completed Not applicable Interventional Results available

Foley Catheter Compared to the Foley Catheter Alone for Cervical Ripening

NCT03111316
View directory record Official record
Conditions
Cervical Ripening, Induction of Labor
Interventions
Cervidil 10 MG Vaginal Insert, Foley Catheter
Drug · Device
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Mar 23, 2021 · Synced Jul 23, 2026, 12:36 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Randomized Control Trial of Intracervical Balloon Placement vs Oxytocin in Women With Term PROM and Unripe Cervices

NCT03172858
View directory record Official record
Conditions
Premature Rupture of Membrane, Unfavorable Cervix
Interventions
Intracervical balloon catheter, Oxytocin
Device · Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 50 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 25, 2024 · Synced Jul 23, 2026, 12:36 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Patient Satisfaction of Cervical Ripening in an Outpatient Setting

NCT01605474
View directory record Official record
Conditions
Pregnancy
Interventions
Patient discharged home after foley bulb placement., Inpatient
Other
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2012
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 24, 2012 · Synced Jul 23, 2026, 12:36 PM EDT
Completed Phase 2 Interventional Results available

Misoprostol Vaginal Insert (MVI) 100, 150, 200 mcg for Cervical Ripening and Induction of Labor

NCT00828711
View directory record Official record
Conditions
Cervical Ripening, Induction of Labor
Interventions
MVI 100, MVI 150, MVI 200
Drug
Lead sponsor
Ferring Pharmaceuticals
Industry
Eligibility
18 Years and older · Female only
Enrollment
374 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
11
States / cities
Phoenix, Arizona • Tucson, Arizona • Long Beach, California + 8 more
Source: ClinicalTrials.gov public record
Updated Apr 20, 2014 · Synced Jul 23, 2026, 12:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mifepristone Versus Laminaria for Cervical Ripening in Midtrimester Induction

NCT00383032
View directory record Official record
Conditions
Abortion, Induced
Interventions
mifepristone
Drug
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
16 Years and older · Female only
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2006
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Oct 23, 2023 · Synced Jul 23, 2026, 12:36 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Inpatient Versus Outpatient Cervical Ripening

NCT03769610
View directory record Official record
Conditions
Pregnancy Related, Labor, Induction, Cervical Ripening
Interventions
Inpatient Foley catheter, Outpatient Foley catheter
Other
Lead sponsor
LifeBridge Health
Other
Eligibility
14 Years to 45 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
2
States / cities
Baltimore, Maryland • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 13, 2021 · Synced Jul 23, 2026, 12:36 PM EDT