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Showing 1–24 of 42 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Cervical Spinal Cord Paralysis Clear all
Recruiting No phase listed Observational

NYSCF Scientific Discovery Biobank

NCT06203106
View directory record Official record
Conditions
ALS, Amyotrophic Lateral Sclerosis, Alzheimer Disease, Alzheimer Disease, Early Onset, Alzheimer Disease, Late Onset, Batten Disease, Corticobasal Degeneration, Dementia, Frontotemporal Dementia, Huntington Disease, Lewy Body Disease, Multiple Sclerosis, Multiple System Atrophy, Parkinson Disease, Parkinson's Disease and Parkinsonism, Progressive Supranuclear Palsy, INAD, Diabetes, Diabetes Mellitus, Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1, Macular Degeneration, Ovarian Cancer, Cervical Cancer, Uterine Cancer, Vaginal Cancer, Vulvar Cancer, PTSD, Post Traumatic Stress Disorder
Interventions
Biological Sample Collection
Other
Lead sponsor
New York Stem Cell Foundation Research Institute
Other
Eligibility
30 Days and older
Enrollment
10,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2045
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 2, 2025 · Synced Sep 16, 2026, 10:45 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Cervical Spinal Cord Associative Plasticity

NCT07539025
View directory record Official record
Conditions
Cervical Spinal Cord Plasticity
Interventions
SCAP, MagPro X100, Digitimer DS8R, Paired non-associative stimulation
Other · Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 16, 2026, 10:45 AM EDT
Terminated Phase 2Phase 3 Interventional Results available

Efficacy and Safety Study of MYOBLOC® in the Treatment of Adult Upper Limb Spasticity

NCT04815967
View directory record Official record
Conditions
Spasticity, Cerebrovascular Accident, Multiple Sclerosis, Traumatic Brain Injury, Cervical Spinal Cord Injury, Cerebral Palsy
Interventions
Phase 2; Low Dose MYOBLOC (10,000 Units), Phase 2; High Dose MYOBLOC (20,000 Units), Phase 2; Placebo, Phase 3; MYOBLOC, Phase 3; Placebo
Drug
Lead sponsor
Solstice Neurosciences, LLC, a subsidiary of MDD US Operations, LLC
Industry
Eligibility
18 Years to 80 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
4
States / cities
Downey, California • Boise, Idaho • Port Royal, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Sep 16, 2026, 10:45 AM EDT
Recruiting Not applicable Interventional

Can Prophylactic Foraminotomy Prevent C5 Palsy

NCT03023696
View directory record Official record
Conditions
Myelopathy, Compressive, Radiculopathy, Cervical, C5 Palsy
Interventions
Bilateral Cervical Keyhole Foraminotomy, Cervical Decompression
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
480 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Sep 16, 2026, 10:45 AM EDT
Not listed Not applicable Interventional

The Use of Electromagnetic Field (EMF) Treatment in Chronic Spinal Cord Injury (SCI) Patients

NCT04050696
View directory record Official record
Conditions
Incomplete Spinal Cord Injury
Interventions
BQ 1.2
Device
Lead sponsor
BrainQ Technologies Ltd.
Industry
Eligibility
18 Years to 75 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
2
States / cities
Miami, Florida • West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 21, 2023 · Synced Sep 16, 2026, 10:45 AM EDT
Recruiting Not applicable Interventional

Targeting Cervical Epidural Spinal Cord Stimulation for Functional Recovery

NCT06701422
View directory record Official record
Conditions
Cervical Spinal Cord Injury, Tetraplegia/Tetraparesis, Cervical Myelopathy
Interventions
Intraoperative stimulation of the cervical spinal cord
Procedure
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 23, 2025 · Synced Sep 16, 2026, 10:45 AM EDT
Active, not recruiting Phase 2 Interventional

Rehabilitation and Cortical Remodeling After Surgical Intervention for Spinal Cord Injury

NCT04041063
View directory record Official record
Conditions
Spinal Cord Injuries, Tetraplegia, Cervical Spinal Cord Injury
Interventions
Upper limb robotic training, Nerve transfer surgery
Device · Procedure
Lead sponsor
Burke Medical Research Institute
Other
Eligibility
18 Years to 50 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Aug 22, 2024 · Synced Sep 16, 2026, 10:45 AM EDT
Active, not recruiting Phase 1Phase 2 Interventional

Spinal Cord Neuromodulation for Spinal Cord Injury

NCT02313194
View directory record Official record
Conditions
Cervical Spinal Cord Injury, Tetraparesis, Tetraplegia
Interventions
Epidural Stimulation, Buspirone
Device · Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Sep 16, 2026, 10:45 AM EDT
Not yet recruiting Phase 3 Interventional

A Trial Investigating the Efficacy and Safety of NVG-291 in Subjects With Chronic Spinal Cord Injury

NCT07799532
View directory record Official record
Conditions
Chronic Spinal Cord Injury
Interventions
NVG-291, Placebo
Drug
Lead sponsor
NervGen Pharma
Industry
Eligibility
18 Years to 75 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
17
States / cities
Birmingham, Alabama • Downey, California • Englewood, Colorado + 14 more
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 16, 2026, 10:45 AM EDT
Recruiting No phase listed Observational

Nerve Transfer to Improve Function in High Level Tetraplegia

NCT06288763
View directory record Official record
Conditions
Cervical Spinal Cord Injury, Tetraplegia
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
9
States / cities
Stanford, California • Miami, Florida • Baltimore, Maryland + 6 more
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Sep 16, 2026, 10:45 AM EDT
Recruiting Not applicable Interventional

Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Tablet-01)

NCT06511934
View directory record Official record
Conditions
Brainstem Stroke, ALS, Tetraplegia, Spinal Cord Injuries, Cervical Spinal Cord Injury
Interventions
BrainGate Neural Interface System
Device
Lead sponsor
Leigh R. Hochberg, MD, PhD.
Other
Eligibility
18 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Sep 16, 2026, 10:45 AM EDT
Recruiting Not applicable Interventional

Development of Optimal Sensory Feedback Strategies to Maximize Function After Tetraplegia

NCT07225582
View directory record Official record
Conditions
Spinal Cord Injury Cervical, Spinal Cord Injuries (Complete and Incomplete)
Interventions
Brain Computer Interface (BCI) - Functional Electrical Stimulation (FES) system
Device
Lead sponsor
Case Western Reserve University
Other
Eligibility
22 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Sep 16, 2026, 10:45 AM EDT
Enrolling by invitation Not applicable Interventional

NIBS Therapy in Subacute Spinal Cord Injury

NCT06247904
View directory record Official record
Conditions
Traumatic Spinal Cord Injury, Tetraplegia/Tetraparesis
Interventions
Active rTMS, sham rTMS
Device
Lead sponsor
Albert Einstein Healthcare Network
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Elkins Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 29, 2025 · Synced Sep 16, 2026, 10:45 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Dose Escalation Study of AST-OPC1 in Spinal Cord Injury

NCT02302157
View directory record Official record
Conditions
Cervical Spinal Cord Injury, Spine Injury, Spinal Cord Trauma
Interventions
AST-OPC1
Biological
Lead sponsor
Lineage Cell Therapeutics, Inc.
Industry
Eligibility
18 Years to 69 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
9
States / cities
La Jolla, California • Los Angeles, California • San Jose, California + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 13, 2021 · Synced Sep 16, 2026, 10:45 AM EDT
Not listed Phase 2 Interventional

Surgical Management of Spinal Cord Injuries In Neck

NCT00475748
View directory record Official record
Conditions
Central Cord Syndrome, Spinal Cord Injury, Quadriparesis
Interventions
Early and late surgery for traumatic central cord syndrome
Procedure
Lead sponsor
Maryland Department of Health and Mental Hygiene
Government
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 23, 2009 · Synced Sep 16, 2026, 10:45 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Exhaled Breath Condensate Biomarkers of Inflammation in Individuals With Chronic Cervical Spinal Cord Injury

NCT02235714
View directory record Official record
Conditions
Tetraplegia, Asthma
Interventions
Not listed
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 89 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Sep 9, 2014 · Synced Sep 16, 2026, 10:45 AM EDT
Completed Phase 1Phase 2 Interventional

A Safety Study for Cethrin (BA-210) in the Treatment of Acute Thoracic and Cervical Spinal Cord Injuries

NCT00500812
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Cethrin
Drug
Lead sponsor
Vertex Pharmaceuticals Incorporated
Industry
Eligibility
16 Years to 70 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
5
States / cities
Phoenix, Arizona • Cincinnati, Ohio • Philadelphia, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 13, 2016 · Synced Sep 16, 2026, 10:45 AM EDT
Not listed Early Phase 1 Interventional

Neuromodulation to Reduce Muscle Stiffness Following Spinal Cord Injury

NCT06274021
View directory record Official record
Conditions
Spinal Cord Injuries, Spinal Cord Injury, Spinal Cord Injury Cervical, Spinal Cord Injury Thoracic
Interventions
Transcutaneous spinal stimulation at 100 Hz, Transcutaneous spinal stimulation at 50 Hz, Transcutaneous spinal stimulation at 50 Hz and single dose of baclofen, Transcutaneous spinal stimulation at 50 Hz and single dose of tizanidine, Sham transcutaneous spinal stimulation
Device · Combination Product
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Jun 30, 2024 · Synced Sep 16, 2026, 10:45 AM EDT
Recruiting Not applicable Interventional

Precise Robotically IMplanted Brain-Computer InterfacE

NCT06429735
View directory record Official record
Conditions
Tetraplegia/Tetraparesis, Quadriplegia, Cervical Spinal Cord Injury, Amyotrophic Lateral Sclerosis, Quadriplegia/Tetraplegia, Tetraplegic; Paralysis
Interventions
N1 Implant, R1 Robot
Device
Lead sponsor
Neuralink Corp
Industry
Eligibility
22 Years to 75 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2031
U.S. locations
2
States / cities
Phoenix, Arizona • Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Sep 16, 2026, 10:45 AM EDT
Completed Not applicable Interventional Results available

Sub-study to Spinal Cord Stimulation to Restore Cough

NCT00995215
View directory record Official record
Conditions
Spinal Cord Injuries, Spinal Cord Diseases, Paralysis, Central Nervous System Diseases, Cough
Interventions
Spinal Cord Stimulation, Expiratory Muscle Stimulator
Procedure · Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2017
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 13, 2020 · Synced Sep 16, 2026, 10:45 AM EDT
Recruiting No phase listed Observational

Nerve Transfers Plus Electrical Stimulation to Improve Hand Function in Cervical Spinal Cord Injury

NCT06541041
View directory record Official record
Conditions
Cervical Spinal Cord Injury, Cervical Spinal Cord Paralysis, Tetraplegia, Tetraplegia/Tetraparesis, Tetraplegic Spinal Paralysis
Interventions
Brief intraoperative electrical stimulation, Temporary Postoperative Peripheral Nerve Stimulation
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Feb 18, 2025 · Synced Sep 16, 2026, 10:45 AM EDT
Recruiting Not applicable Interventional

Investigation on the Bidirectional Cortical Neuroprosthetic System

NCT03161067
View directory record Official record
Conditions
Tetraplegia, Quadriplegia
Interventions
BiCNS
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
22 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2030
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Sep 16, 2026, 10:45 AM EDT
Recruiting Not applicable Interventional

Spinal Cord Associative Plasticity in Cerebral Palsy

NCT07607665
View directory record Official record
Conditions
Hemiplegic Cerebral Palsy
Interventions
Paired brain and nerve stimulation
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 13, 2026 · Synced Sep 16, 2026, 10:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Neuromodulation After Spinal Cord Injury to Improve Limb Function

NCT06815601
View directory record Official record
Conditions
Spinal Cord Injury, Spinal Cord Injury Cervical
Interventions
rTMS, Sham rTMS, Motor training
Other · Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years to 75 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Sep 7, 2026 · Synced Sep 16, 2026, 10:45 AM EDT