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Showing 1–24 of 143 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Cervical Spine Clear all
Recruiting Phase 4 Interventional

Multifidus Cervicis Plane Block Vs. Sham Block For Posterior Cervical Spine Fusion Surgery

NCT05996133
View directory record Official record
Conditions
Cervical Spine Fusion
Interventions
Bupivacaine Hcl 0.25% Inj, Normal saline
Drug · Other
Lead sponsor
Hartford Hospital
Other
Eligibility
40 Years to 80 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 4, 2025 · Synced Sep 7, 2026, 3:17 AM EDT
Withdrawn Phase 2 Interventional

Whether Proton Pump Inhibitors, Administered Prior to or After Surgery, Can Reduce the Incidence and/or Severity of Difficulty Swallowing Foods and/or Liquids,Following Anterior Cervical Surgery

NCT03488147
View directory record Official record
Conditions
Dysphagia, GERD, Degenerative Joint Disease
Interventions
Esomeprazole, Placebo Oral Tablet
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 22, 2020 · Synced Sep 7, 2026, 3:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Cervical Spine Manipulation on Gait

NCT02287324
View directory record Official record
Conditions
Cervicalgia
Interventions
Manipulation, Manual Contact
Procedure
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Nov 9, 2014 · Synced Sep 7, 2026, 3:17 AM EDT
Not listed No phase listed Observational

Pediatric Cervical Spine Clearance: A Multicenter Prospective Observational Study

NCT05608460
View directory record Official record
Conditions
Cervical Spine Fracture
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
0 Years to 17 Years
Enrollment
15,700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
9
States / cities
Phoenix, Arizona • Los Angeles, California • San Diego, California + 6 more
Source: ClinicalTrials.gov public record
Updated Nov 7, 2022 · Synced Sep 7, 2026, 3:17 AM EDT
Completed Not applicable Interventional Results available

Study of the Safety and Effectiveness of the Artificial Cervical Disc - Low Profile Device at Two Adjacent Levels

NCT00637156
View directory record Official record
Conditions
Cervical Degenerative Disc Disease, Radiculopathy, Myelopathy
Interventions
PRESTIGE LP device at two adjacent levels, Bi-level fusion with ATLANTIS Cervical Plate System
Device
Lead sponsor
Medtronic Spinal and Biologics
Industry
Eligibility
18 Years and older
Enrollment
397 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2018
U.S. locations
29
States / cities
Huntsville, Alabama • Beverly Hills, California • Colton, California + 26 more
Source: ClinicalTrials.gov public record
Updated Apr 30, 2018 · Synced Sep 7, 2026, 3:17 AM EDT
Completed No phase listed Observational

Osteocel® Plus in Anterior Cervical Discectomy and Fusion (ACDF)

NCT00942045
View directory record Official record
Conditions
Degenerative Disc Disease in Cervical Spine
Interventions
Biologic - Osteocel Plus
Biological
Lead sponsor
NuVasive
Industry
Eligibility
18 Years to 70 Years
Enrollment
182 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
17
States / cities
La Jolla, California • Redwood City, California • San Diego, California + 14 more
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Sep 7, 2026, 3:17 AM EDT
Active, not recruiting Phase 2 Interventional

Thermal Ablation and Spine Stereotactic Radiosurgery in Treating Patients With Spine Metastases at Risk for Compressing the Spinal Cord

NCT02713269
View directory record Official record
Conditions
Malignant Digestive System Neoplasm, Metastatic Head and Neck Carcinoma, Metastatic Kidney Carcinoma, Metastatic Malignant Neoplasm in the Spine, Metastatic Malignant Neoplasm of Unknown Primary, Metastatic Melanoma, Prostate Carcinoma Metastatic in the Bone, Sarcoma, Solid Neoplasm, Spinal Cord Compression, Stage IV Breast Cancer AJCC v6 and v7, Stage IV Lung Non-Small Cell Cancer AJCC v7, Thyroid Gland Carcinoma
Interventions
Computed Tomography, Quality-of-Life Assessment, Questionnaire Administration, Stereotactic Radiosurgery, Thermal Ablation Therapy
Procedure · Other · Radiation
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Sep 7, 2026, 3:17 AM EDT
Not yet recruiting Phase 2 Interventional

Pharmacologic Therapies to Mitigate Radiation- Associated Heart Disease

NCT07685938
View directory record Official record
Conditions
Chest Wall Tumor, Breast Cancer, Lung Cancer, Esophageal Cancer, Mediastinal Cancers, Spine Metastases, Spinal Tumor, Thoracic Cancer, Thoracic Neoplasms
Interventions
Atorvastatin and Lisinopril, Placebo
Drug
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 7, 2026, 3:17 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effect of Orthopedic Blocking on Cervical Spine Flexion and Extension Strength

NCT00758888
View directory record Official record
Conditions
Sacroiliac Function
Interventions
Orthopedic Blocking, Trochanter Belt, Blocking Sham
Procedure · Other
Lead sponsor
Logan College of Chiropractic
Other
Eligibility
18 Years to 30 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
Chesterfield, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 23, 2009 · Synced Sep 7, 2026, 3:17 AM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Wearable Spine Health System for Military Readiness

NCT05944354
View directory record Official record
Conditions
Low Back Pain, Neck Pain
Interventions
Not listed
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 64 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2032
U.S. locations
6
States / cities
Luke Air Force Base, Arizona • Holloman Air Force Base, New Mexico • Seymour-Johnson Air Force Base, North Carolina + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Sep 7, 2026, 3:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Postural Realignment on Postural Stability and Visual Reliance in Older Adults

NCT05032274
View directory record Official record
Conditions
Forward Head Posture
Interventions
Home-based Exercise Program
Other
Lead sponsor
Loma Linda University
Other
Eligibility
65 Years to 74 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Oct 1, 2024 · Synced Sep 7, 2026, 3:17 AM EDT
Not yet recruiting No phase listed Observational

Assessing Safety of Cervical Spine Fusion With NMP®

NCT07245940
View directory record Official record
Conditions
Degenerative Disc Disease, Degenerative Spondylolisthesis, Spinal Stenosis Cervical
Interventions
Natural Matrix Protein (NMP) Fibers, Cervical interbody fusion
Biological · Procedure
Lead sponsor
Red Rock Regeneration Inc.
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Jasper, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 23, 2025 · Synced Sep 7, 2026, 3:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Objective Kinematic Correlates of Palpatory Diagnosis

NCT00728247
View directory record Official record
Conditions
Cervical Spine
Interventions
Manual Therapy Techniques
Procedure
Lead sponsor
Michigan State University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
East Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 19, 2010 · Synced Sep 7, 2026, 3:17 AM EDT
Completed Not applicable Interventional Results available

Spine Pain INtervention to Enhance Care Quality And Reduce Expenditure

NCT03083886
View directory record Official record
Conditions
Back Pain, Neck Pain
Interventions
Identify, Coordinated, Enhanced (ICE) Decision Making + PCP led care, Individualized Postural Therapy (IPT) + PCP led care, Usual PCP led care
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
3,087 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
8
States / cities
Phoenix, Arizona • Laguna Hills, California • North Hollywood, California + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Sep 7, 2026, 3:17 AM EDT
Completed Not applicable Interventional

Development of a Clinical Prediction Rulefor Neck Manipulation

NCT01620905
View directory record Official record
Conditions
Mechanical Neck Pain
Interventions
Manipulation
Procedure
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years to 60 Years
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated May 11, 2016 · Synced Sep 7, 2026, 3:17 AM EDT
Completed Phase 1Phase 2 Interventional

Charged Particle RT for Chordomas and Chondrosarcomas of the Base of Skull or Cervical Spine

NCT00592748
View directory record Official record
Conditions
Chordoma, Chondrosarcoma
Interventions
Charged Particle Radiation Therapy
Radiation
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
381 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 15, 2017 · Synced Sep 7, 2026, 3:17 AM EDT
Completed Not applicable Interventional Results available

Dispersal Pattern for Spine Injections (Gadolinium Contrast)

NCT02217280
View directory record Official record
Conditions
Cervical Radiculopathy
Interventions
Injection with Gadolinium
Drug
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 27, 2017 · Synced Sep 7, 2026, 3:17 AM EDT
Recruiting Not applicable Interventional

Evaluation of Safety and Effectiveness of Primary Hybrid Construct of Mobi-C and ACDF in the Treatment of Two-level Symptomatic Degenerative Disc Disease in the Cervical Spine.

NCT06485206
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
One level Mobi-C and one level fusion
Device
Lead sponsor
Highridge Medical
Industry
Eligibility
22 Years to 69 Years
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
2
States / cities
Sacramento, California • Southfield, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 26, 2025 · Synced Sep 7, 2026, 3:17 AM EDT
Not listed No phase listed Observational

Intraoperative Monitoring (IOM) Patient Registry

NCT02187653
View directory record Official record
Conditions
Intraoperative Monitoring, Spinal Diseases
Interventions
Not listed
Lead sponsor
DC2 Healthcare
Industry
Eligibility
18 Years and older
Enrollment
10,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 10, 2014 · Synced Sep 7, 2026, 3:17 AM EDT
Completed Not applicable Interventional

Cervical Spine Biomechanics During Endotracheal Intubation

NCT01369381
View directory record Official record
Conditions
Spinal Diseases, Other Biomechanical Lesions of Cervical Region, Tracheal Intubation Morbidity
Interventions
Endotracheal intubation
Procedure
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 80 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 6, 2012 · Synced Sep 7, 2026, 3:17 AM EDT
Terminated Not applicable Interventional

Study of the Effect of Neck Treatment on Shoulder Impingement

NCT00764764
View directory record Official record
Conditions
Shoulder Impingement, Shoulder Pain, Rotator Cuff Tendinitis, Cervical Degenerative Joint Disease
Interventions
shoulder treatment, Shoulder AND cervical treatment
Procedure
Lead sponsor
CAMC Health System
Other
Eligibility
40 Years to 70 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Charleston, West Virginia
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 7, 2026, 3:17 AM EDT
Recruiting No phase listed Observational

Evaluation of the Effects of a Rehabilitation Program in Individuals with Spine Pain

NCT04081896
View directory record Official record
Conditions
Neck Pain, Low Back Pain, Scoliosis, Thoracic Injuries
Interventions
Exercise
Other
Lead sponsor
SpineZone Medical Fitness, Inc
Other
Eligibility
18 Years to 89 Years
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2029
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 28, 2024 · Synced Sep 7, 2026, 3:17 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Fusion Status After ACDF

NCT05986006
View directory record Official record
Conditions
Spine Fusion, Spine Surgery
Interventions
Anterior Cervical Disc Fusion (ACDF) Surgery w/ machined bone allograft, Anterior Cervical Disc Fusion (ACDF) Surgery w/ Iliac Crest Bone Graft
Procedure
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 13, 2023 · Synced Sep 7, 2026, 3:17 AM EDT
Completed No phase listed Observational

Prospective Study of Post Surgical Continued Spinal Pain Patients

NCT05401682
View directory record Official record
Conditions
Low Back Pain, Cervical Pain, Neck Disorder, Low Back Disorder, Spine Injury
Interventions
Cox chiropractic care
Other
Lead sponsor
Keiser University College of Chiropractic Medicine
Other
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
West Palm Beach, Florida
Source: ClinicalTrials.gov public record
Updated Aug 7, 2022 · Synced Sep 7, 2026, 3:17 AM EDT