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ClinicalTrials.gov public records Last synced Nov 14, 2026, 9:03 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 164 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Chronic Neuropathic Pain Clear all

Conditions: Neuropathic Pain
Interventions: oxytocin 100 micrograms, Normal Saline (preservative free); Drug
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years to 70 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2022
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Intractable Neuropathic Pain, Pain, Back Pain, Lower Extremity Pain
Interventions: Precision for Spinal Cord Stimulation; Device
Lead sponsor: Boston Scientific Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Belleville, Illinois

Conditions: Lumbosacral Radiculopathy, Sciatica, Chronic Low Back Pain With a Neuropathic Component, Radiculopathy Lumbar, Chronic Pain (Back / Neck)
Interventions: Move-MORE; Behavioral
Lead sponsor: National University of Natural Medicine; Other
Eligibility: 18 Years to 75 Years
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Diabetic Peripheral Neuropathic Pain
Interventions: LY3857210, Placebo; Drug
Lead sponsor: Eli Lilly and Company; Industry
Eligibility: 18 Years and older
Enrollment: 131 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 28
States / cities: Chandler, Arizona • Phoenix, Arizona • Riverside, California + 23 more

Conditions: Diabetic Peripheral Neuropathy
Interventions: Bicifadine; Drug
Lead sponsor: XTL Biopharmaceuticals; Industry
Eligibility: 18 Years and older
Enrollment: 336 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: Paducah, Kentucky

Conditions: Complex Regional Pain Syndrome, Sciatica
Interventions: [18F]-FTC-146; Drug
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Stanford, California

Conditions: Diabetic Neuropathies, Neuropathic Pain, Pain, Chronic
Interventions: Omnitram Oral Tablet, Placebo Oral Tablet; Drug
Lead sponsor: Syntrix Biosystems, Inc.; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 55 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 4
States / cities: Anaheim, California • Cerritos, California • St Louis, Missouri + 1 more

Conditions: Neuralgia, Spinal Cord Injuries, Chronic Pain
Interventions: Somatic IVR (sIVR), Distractive IVR (dIVR), Control IVR (cIVR); Device
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years and older
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: New York, New York

Conditions: Chronic Pain, Pediatric Disorder, Neuropathic Pain, Nociceptive Pain
Interventions: [18F]FTC-146; Drug
Lead sponsor: Stanford University; Other
Eligibility: 11 Years to 18 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Stanford, California

Conditions: Migraine in Children, Pain, Neuropathic
Interventions: Headache Journal, Sphenopalatine Block, Tx360; Other · Drug · Device
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 8 Years to 17 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Chronic Neuropathic Pain, Radiculopathy, Sciatica, Peripheral Neuropathic Pain
Interventions: Hypersound RF-PNS system, Sham Hypersound; Device
Lead sponsor: Hypersound Medical Inc; Industry
Eligibility: 18 Years and older
Enrollment: 71 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2028
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Complex Regional Pain Syndromes
Interventions: Ketamine, Midazolam, Normal Saline; Drug
Lead sponsor: Stanford University; Other
Eligibility: 18 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2099
U.S. locations: 1
States / cities: Stanford, California

Conditions: Spinal Cord Injury, Hyperalgesia, Secondary, Hyperalgesic Sensations
Interventions: Not listed
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years to 70 Years
Enrollment: 94 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Diabetic Peripheral Neuropathic Pain
Interventions: LY4065967, Placebo; Drug
Lead sponsor: Eli Lilly and Company; Industry
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 35
States / cities: Birmingham, Alabama • Phoenix, Arizona • Palm Springs, California + 30 more

Conditions: Painful Diabetic Neuropathy
Interventions: Senza HF10 Therapy, CMM; Device · Other
Lead sponsor: Nevro Corp; Industry
Eligibility: 22 Years and older
Enrollment: 430 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 4
States / cities: Bradenton, Florida • Stockbridge, Georgia • Durham, North Carolina + 1 more

Conditions: Eye Pain
Interventions: High frequency forehead TENS, Low frequency forehead TENS; Device
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 39 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Low Back Pain
Interventions: Milnacipran, Placebo; Drug
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Pain, Neuropathic
Interventions: Ketamine, (2R,6R)-hydroxynorketamine, Saline; Drug
Lead sponsor: Rush University Medical Center; Other
Eligibility: 18 Years to 75 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Pulmonary Dysfunction, Median Sternotomy Recovery, Postoperative Pain
Interventions: Intercostal Nerve Cryoablation; Device
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 40 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: New Brunswick, New Jersey

Conditions: Peripheral Neuralgia, Chronic Pain
Interventions: Nalu Neurostimulation System for PNS, conventional medical management; Device · Other
Lead sponsor: Nalu Medical, Inc.; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 131 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 13
States / cities: Scottsdale, Arizona • Little Rock, Arkansas • Burbank, California + 10 more

Conditions: Chronic Pain, Sciatica, Failed Back Surgery Syndrome
Interventions: Awake, Non-Awake; Procedure
Lead sponsor: St. Luke's Hospital, Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 4
States / cities: Bethlehem, Pennsylvania • Danville, Pennsylvania • Hershey, Pennsylvania + 1 more

Conditions: Lumbosacral Radicular Pain, Sciatic Radiculopathy, Sciatic Leg Pain, Sciatica, Lumbosacral Radicular Syndrome, Lumbosacral Radiculopathy
Interventions: C-1101, Placebo: Sterile Saline; Drug · Other
Lead sponsor: Consano Bio; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 3
States / cities: Fernandina Beach, Florida • Winston-Salem, North Carolina • Richmond, Virginia

Conditions: Brachial Plexus Injury
Interventions: Not listed
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 2
States / cities: Jacksonville, Florida • Rochester, Minnesota

Conditions: Chronic Low-Back Pain, Refractory Pain, Neuropathic Pain
Interventions: Spinal Cord Stimulation, Conventional Medical Management; Device · Other
Lead sponsor: Abbott Medical Devices; Industry
Eligibility: 18 Years and older
Enrollment: 270 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2024
U.S. locations: 30
States / cities: Phoenix, Arizona • Tucson, Arizona • Camarillo, California + 27 more

Search by objective public record fields.

Efficacy of Intrathecal Oxytocin in Patients With Neuropathic Pain

Spinal Cord Stimulation (SCS) for Neuropathic Pain of Back or Lower Extremity

A Multicomponent Intervention for Patients With Lumbosacral Radiculopathy: Move-MORE

A Chronic Pain Master Protocol (CPMP): A Study of LY3857210 in Participants With Diabetic Peripheral Neuropathic Pain (NP05).

Double Blind RCT of Bicifadine SR in Outpatients With Chronic Neuropathic Pain Associated With Diabetes

[18F]FTC-146 PET/MRI in Healthy Volunteers and in CRPS and Sciatica

Omnitram Safety and Efficacy in the Treatment of Diabetic Neuropathy

Immersive Virtual Reality for Chronic Neuropathic Pain After Spinal Cord Injury: A Feasibility Trial

PET/MRI in the Diagnosis of Pediatric Chronic Pain

Transnasal Sphenopalatine Ganglia Block for Management of Chronic Migraines in Pediatric Patients

Hypersound Treatment for Chronic Neuropathic and Radicular Pain

Ketamine and Midazolam Infusions for CRPS: Feasibility Study

MR Spectroscopy as a Diagnostic and Outcome Measure in Pain and SCI

A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Diabetic Peripheral Neuropathic Pain

Comparison of 10 kHz SCS Combined With CMM to CMM Alone in the Treatment of Neuropathic Limb Pain

Pilot Study of TENS for Ocular Pain

Effect of Milnacipran in Chronic Neuropathic Low Back Pain

(2R,6R)-Hydroxynorketamine for the Treatment of Neuropathic Pain

FROST-STERN Trial: A Trial of Intraoperative Cryoablation for Post Operative Pain Management After Full Sternotomy

Clinical Study Of a Micro-Implantable Pulse Generator For The Treatment of Peripheral Neuropathic Pain

NAPS: Non-awake Versus Awake Placement of Spinal Cord Stimulators

Study to Evaluate Safety of C-1101 Versus Sterile Saline in Adults With Chronic Painful Lumbosacral Radiculopathy

Neurostimulation for Treatment of Chronic Upper Limb Pain After Brachial Plexus Injury

Spinal Cord Stimulation vs. Medical Management for Low Back Pain (DISTINCT)