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ClinicalTrials.gov public records Last synced Oct 24, 2026, 4:25 AM EDT

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Showing 1–24 of 435 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Chronic Pain Management Clear all
Recruiting Not applicable Interventional

Options for Pain Management Using Nonpharmacological Strategies

NCT05563792
View directory record Official record
Conditions
Pain
Interventions
Options for Pain Management using Non-medication Strategies
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
296 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 15, 2026 · Synced Oct 24, 2026, 4:25 AM EDT
Completed Phase 4 Interventional Results available

PENG Block Versus LP Block for THA Postop Pain

NCT05261009
View directory record Official record
Conditions
Pain, Postoperative, Hip Pain Chronic
Interventions
Peri-capsular Nerve Group (PENG), Lumbar Plexus Block (LPB)
Drug · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 90 Years
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 21, 2024 · Synced Oct 24, 2026, 4:25 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Enhancing Analgesia in Chronic Pain Through Exercise

NCT04862871
View directory record Official record
Conditions
Pain, Chronic Widespread Pain, Fibromyalgia
Interventions
Physical Activity - Pediatric Pain Rehabilitation Center
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
10 Years to 24 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 11, 2022 · Synced Oct 24, 2026, 4:25 AM EDT
Active, not recruiting Early Phase 1 Interventional

Improving Pain Management Via Spinal Cord Stimulation and Blood Pressure Reduction

NCT04676399
View directory record Official record
Conditions
Chronic Pain, Hypertension, Diuretics Drug Reactions, SCS
Interventions
Hydrochlorothiazide 12.5mg, Placebo
Drug
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
40 Years to 79 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 24, 2026, 4:25 AM EDT
Terminated Not applicable Interventional

Complementary Management of Chronic Neck and/or Low Back Pain With a Pain Relief Kit

NCT03157544
View directory record Official record
Conditions
Pain, Chronic, Musculoskeletal Pain, Low Back Pain, Neck Pain
Interventions
multimodal non-pharmacological Pain Relief Kit
Behavioral
Lead sponsor
Sport and Spine Rehab Clinical Research Foundation
Other
Eligibility
18 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
2
States / cities
Fairfax, Virginia • McLean, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 2, 2024 · Synced Oct 24, 2026, 4:25 AM EDT
Completed Not applicable Interventional

Using Immersive Virtual Reality to Treat Complex Regional Pain Syndrome in Adults

NCT05888142
View directory record Official record
Conditions
Pain, Chronic
Interventions
in clinic pain VR reduction exercises, In clinic VRpain reduction exercises + VR homeworks
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 85 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 6, 2024 · Synced Oct 24, 2026, 4:25 AM EDT
Terminated Not applicable Interventional

Improving Outcomes and Lowering Costs by Integration of Primary Care Providers and Pain Medicine Physicians for Pain Pts

NCT02484937
View directory record Official record
Conditions
Back Pain, Chronic Pain, Pain, Intractable
Interventions
Group 2 (PCP Treatment), Group 1 (PMS Treatment)
Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 29, 2022 · Synced Oct 24, 2026, 4:25 AM EDT
Not listed Not applicable Interventional

Assessment of Urinary Polymerase Chain Reaction (PCR) and Next Generation Sequencing (NGS) Technology in the Evaluation and Management of Females With Chronic Bladder Pain and Cystitis-like Symptoms

NCT05276466
View directory record Official record
Conditions
Interstitial Cystitis, Bladder Pain Syndrome
Interventions
Polymerase Chain Reaction and Next-Generation DNA Sequencing
Diagnostic Test
Lead sponsor
MicroGenDX
Industry
Eligibility
18 Years to 80 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
4
States / cities
Los Angeles, California • San Diego, California • Camden, New Jersey + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 15, 2023 · Synced Oct 24, 2026, 4:25 AM EDT
Completed Phase 3 Interventional Results available

Long-term Open-Label Safety Study to Evaluate EN3409

NCT01755546
View directory record Official record
Conditions
Low Back Pain, Osteoarthritis, Neuropathic Pain
Interventions
EN3409
Drug
Lead sponsor
BioDelivery Sciences International
Industry
Eligibility
18 Years and older
Enrollment
304 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
57
States / cities
Birmingham, Alabama • Mobile, Alabama • Phoenix, Arizona + 52 more
Source: ClinicalTrials.gov public record
Updated Oct 18, 2018 · Synced Oct 24, 2026, 4:25 AM EDT
Completed Not applicable Interventional

Acupuncture for Chronic Pain

NCT01149317
View directory record Official record
Conditions
Chronic Pain
Interventions
Acupuncture
Procedure
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
21 Years and older
Enrollment
235 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jan 31, 2012 · Synced Oct 24, 2026, 4:25 AM EDT
Terminated No phase listed Observational

An Observational, Non-Interventional Trial to Assess Patient Satisfaction and Safety of Subsys™ Spray.

NCT01901718
View directory record Official record
Conditions
Breakthrough Pain
Interventions
Not listed
Lead sponsor
International Clinical Research Institute
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Sep 4, 2014 · Synced Oct 24, 2026, 4:25 AM EDT
Not listed Phase 1 Interventional Accepts healthy volunteers

The Study of Hemp Oil CBD for Evaluation of Efficacy and Safety in Treatment of Pain, Anxiety and Insomnia Management

NCT04729244
View directory record Official record
Conditions
CBD, Pain, Chronic, Anxiety, Insomnia, Opioid Use
Interventions
CBD
Drug
Lead sponsor
Advanced Pain and Rehab Specialists
Other
Eligibility
18 Years to 90 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Hermitage, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 6, 2021 · Synced Oct 24, 2026, 4:25 AM EDT
Completed Not applicable Interventional Results available

TMS Treatment for Pain in Chronic Pancreatitis

NCT00250484
View directory record Official record
Conditions
Idiopathic Chronic Pancreatitis, Pain
Interventions
Transcranial Magnetic Stimulation, Sham Transcranial Magnetic Stimulation
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 11, 2017 · Synced Oct 24, 2026, 4:25 AM EDT
Recruiting Not applicable Interventional

Pain Management Teams Using Whole Health to Optimize Function and Safety in Veterans: The TEAMWORK Trial

NCT07149870
View directory record Official record
Conditions
Chronic Pain
Interventions
Pain Management Team + Whole Health Coach (PMT-WHC), Pain Management Team-Usual Care (PMT-UC)
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
432 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
5
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Aurora, Colorado + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 24, 2026, 4:25 AM EDT
Completed No phase listed Observational

E-health for Self-Management of Chronic Pain

NCT04628650
View directory record Official record
Conditions
Chronic Pain
Interventions
Digital Pain-Management Tool
Device
Lead sponsor
Lund University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 13, 2023 · Synced Oct 24, 2026, 4:25 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Efficacy of a Chronic Pain Treatment Prior to Gender-affirming Surgery

NCT06443164
View directory record Official record
Conditions
Pain Catastrophizing, Pain, Chronic, Gender Identity
Interventions
Empowered Relief, Standard of Care
Behavioral · Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 100 Years
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 31, 2025 · Synced Oct 24, 2026, 4:25 AM EDT
Completed Not applicable Interventional Results available

Management of Chronic Low Back Pain in Older Adults Using Auricular Point Acupressure

NCT03589703
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Target ear points related to chronic low back pain (T-APA), Non-Target ear Points not related to chronic low back pain (NT-APA), Enhanced Educational Control Group (CG-2)
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
60 Years and older
Enrollment
272 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
2
States / cities
Baltimore, Maryland • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 24, 2024 · Synced Oct 24, 2026, 4:25 AM EDT
Recruiting Phase 1 Interventional

Study to Evaluate Safety of C-1101 Versus Sterile Saline in Adults With Chronic Painful Lumbosacral Radiculopathy

NCT07264270
View directory record Official record
Conditions
Lumbosacral Radicular Pain, Sciatic Radiculopathy, Sciatic Leg Pain, Sciatica, Lumbosacral Radicular Syndrome, Lumbosacral Radiculopathy
Interventions
C-1101, Placebo: Sterile Saline
Drug · Other
Lead sponsor
Consano Bio
Industry
Eligibility
18 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
3
States / cities
Fernandina Beach, Florida • Winston-Salem, North Carolina • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 21, 2026 · Synced Oct 24, 2026, 4:25 AM EDT
Completed Not applicable Interventional Results available

Perioperative Pain Management In Spine Surgery Patients: Part I

NCT01447888
View directory record Official record
Conditions
Pain
Interventions
150% Oral Morphine Equivalent (OME), Clinical Judgment
Drug · Other
Lead sponsor
Allina Health System
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 27, 2020 · Synced Oct 24, 2026, 4:25 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

COMmunity of Practice And Safety Support for Navigating Pain (COMPASS-NP)

NCT05492903
View directory record Official record
Conditions
Pain Management, Ergonomics, Wounds and Injuries
Interventions
COMmunity of Practice And Safety Support for Navigating Pain (COMPASS-NP)
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 28, 2025 · Synced Oct 24, 2026, 4:25 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

To Evaluate if the Medication Gabapentin Lessens Vulvar Pain

NCT00390013
View directory record Official record
Conditions
Vulvar Pain Symptoms, Vulvodynia (Chronic Vulvar Pain)
Interventions
Gabapentin, Placebo oral capsule
Drug
Lead sponsor
Colleen Stockdale
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 31, 2017 · Synced Oct 24, 2026, 4:25 AM EDT
Completed Not applicable Interventional

Targeting Effective Analgesia in Clinics for HIV - Intervention

NCT02564341
View directory record Official record
Conditions
HIV Infection, Pain, Drug Dependence
Interventions
Collaboration with an IT enabled nurse care manager, Education and academic detailing, Facilitated access to a specialist in addictions
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
2
States / cities
Atlanta, Georgia • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 20, 2018 · Synced Oct 24, 2026, 4:25 AM EDT
Completed Phase 2Phase 3 Interventional

The Clinical Evaluation of Implantable Pump System For Safety And Delivery Accuracy In Patients Requiring Intrathecal Administration Of Morphine Sulfate For Chronic Pain

NCT01185470
View directory record Official record
Conditions
Cancers, Chronic Pain
Interventions
Implantation of Morphine Sulfate delivering programmable pump
Device
Lead sponsor
Medallion Therapeutics, Inc.
Industry
Eligibility
21 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
9
States / cities
Scottsdale, Arizona • Carlsbad, California • La Jolla, California + 6 more
Source: ClinicalTrials.gov public record
Updated Apr 24, 2017 · Synced Oct 24, 2026, 4:25 AM EDT
Active, not recruiting Not applicable Interventional

Telehealth for Pain and Unhealthy Drinking Among PLWH

NCT05503173
View directory record Official record
Conditions
HIV, Chronic Pain, Unhealthy Alcohol Use
Interventions
MCBMAP, Brief Advice and Information
Behavioral · Other
Lead sponsor
Boston University
Other
Eligibility
18 Years and older
Enrollment
253 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Oct 24, 2026, 4:25 AM EDT