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Showing 1–24 of 346 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Chronic Pain Syndrome Clear all
Terminated Phase 3 Interventional Results available

rTMS for the Treatment of Chronic Pain in GW1 Veterans

NCT01608321
View directory record Official record
Conditions
Chronic Pain
Interventions
rTMS, Sham device
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 10, 2017 · Synced Sep 9, 2026, 8:30 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Sub-Sensory Intraspinal Neurostimulation Therapy

NCT01976598
View directory record Official record
Conditions
Back Pain, Back Pain With Radiation, Pain in Leg, Unspecified
Interventions
Sub-Sensory Stimulation
Other
Lead sponsor
Algos Clinical Development Thomas L. Yearwood, MD, PhD
Other
Eligibility
22 Years to 85 Years
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Pascagoula, Mississippi
Source: ClinicalTrials.gov public record
Updated Jan 18, 2015 · Synced Sep 9, 2026, 8:30 AM EDT
Completed Not applicable Interventional

Music in Reducing Anxiety and Pain in Adult Patients Undergoing Bone Marrow Biopsy for Hematologic Cancers or Other Diseases

NCT00376922
View directory record Official record
Conditions
Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Lymphoproliferative Disorder, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms, Pain, Precancerous Condition, Psychosocial Effects of Cancer and Its Treatment
Interventions
music therapy
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 120 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 29, 2017 · Synced Sep 9, 2026, 8:30 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Chronic Postconcussive Headache: A Placebo-Controlled Treatment Trial of Prazosin

NCT02266329
View directory record Official record
Conditions
Posttraumatic Headache, Combat Disorders, Post Concussion Syndrome, Headache, Mild Traumatic Brain Injury, Posttraumatic Migraine
Interventions
prazosin hydrochloride, placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Sep 9, 2026, 8:30 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Vaginal Baclofen Suppositories in Chronic Pelvic Pain

NCT05968937
View directory record Official record
Conditions
Chronic Pelvic Pain Syndrome
Interventions
20 mg baclofen vaginal suppository daily per vagina, Placebo
Drug
Lead sponsor
University of Louisville
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 9, 2026, 8:30 AM EDT
Completed Not applicable Interventional Results available

PEMF Therapy to Treat Interstitial Cystitis/Bladder Pain Syndrome

NCT04540887
View directory record Official record
Conditions
Interstitial Cystitis, Chronic Interstitial Cystitis, Bladder Pain Syndrome
Interventions
Pulsed Electromagnetic Field (PEMF) Therapy
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 4, 2022 · Synced Sep 9, 2026, 8:30 AM EDT
Completed Not applicable Interventional

Delivered Dietary Intervention for Children With Irritable Bowel Syndrome

NCT01339117
View directory record Official record
Conditions
Irritable Bowel Syndrome, Abdominal Pain
Interventions
Low fermentable substrate diet, High fermentable substrate diet
Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
7 Years to 17 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 21, 2021 · Synced Sep 9, 2026, 8:30 AM EDT
Terminated No phase listed Observational

Prevalence of Secondary Hypogonadism in Male Patients on Chronic Opioid Therapy for Cancer-Related Pain Syndromes

NCT00529230
View directory record Official record
Conditions
Advanced Cancer, Hypogonadism, Pain
Interventions
Questionnaire, Blood draws to assess gonadal function
Behavioral · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Male only
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2004
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 24, 2018 · Synced Sep 9, 2026, 8:30 AM EDT
Withdrawn Not applicable Interventional

Coordinated Reset Spinal Cord Stimulation

NCT04997278
View directory record Official record
Conditions
Pain, Neuropathic, Failed Back Surgery Syndrome
Interventions
Coordinated Reset spinal cord stimulation
Device
Lead sponsor
Stanford University
Other
Eligibility
22 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Sep 7, 2023 · Synced Sep 9, 2026, 8:30 AM EDT
Completed Not applicable Interventional Results available

Sleep Disordered Breathing and Chronic Pain

NCT01457014
View directory record Official record
Conditions
Sleep Apnea Syndromes
Interventions
servo ventilation auto, Continuous positive airway pressure, servo ventilation manual
Device
Lead sponsor
Philips Respironics
Industry
Eligibility
21 Years to 70 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
4
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Atlanta, Georgia + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 18, 2016 · Synced Sep 9, 2026, 8:30 AM EDT
Completed Not applicable Interventional Results available

The Effect of Intravenous Lidocaine on Allodynia

NCT00659633
View directory record Official record
Conditions
Pain
Interventions
lidocaine
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 20, 2017 · Synced Sep 9, 2026, 8:30 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Mechanisms of Neural Mobilization in the Treatment of Chronic Pain

NCT00929123
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
neural mobilization, sham neural mobilization, healthy controls
Procedure · Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 16, 2015 · Synced Sep 9, 2026, 8:30 AM EDT
Withdrawn Phase 4 Interventional

Testosterone and Pain Sensitivity

NCT01689896
View directory record Official record
Conditions
Low Testosterone, Hypogonadism, Pain
Interventions
Testosterone Gel, Placebo Gel
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 30, 2015 · Synced Sep 9, 2026, 8:30 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of a Yoga Intervention on Pain and Multiomics in Participants With IBS

NCT04315714
View directory record Official record
Conditions
Irritable Bowel Syndrome, Abdominal Pain
Interventions
Yoga Program
Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 55 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 1, 2021 · Synced Sep 9, 2026, 8:30 AM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

Repetitive Transcranial Magnetic Stimulation for Post-concussion Headaches

NCT06112093
View directory record Official record
Conditions
Brain Concussion, Mild Traumatic Brain Injury, Headache, Post-Concussion Symptoms
Interventions
Repetitive Transcranial Magnetic Stimulation, Sham Repetitive Transcranial Magnetic Stimulation
Device
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years to 55 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Oct 9, 2025 · Synced Sep 9, 2026, 8:30 AM EDT
Withdrawn Phase 2 Interventional

Trial to Evaluate the Efficacy of Topical Capsaicin to Reduce Pain and Improve Health-related Quality of Life in Adults With Chronic Myofascial Neck Pain

NCT00795106
View directory record Official record
Conditions
Myofascial Pain Syndrome
Interventions
Capsaicin, Placebo
Drug
Lead sponsor
Stamford Hospital
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Stamford, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 5, 2016 · Synced Sep 9, 2026, 8:30 AM EDT
Completed Phase 2 Interventional

Safety and Efficacy Study of GRT6005 in Patients With Osteoarthritis (OA) Knee Pain

NCT01709214
View directory record Official record
Conditions
Moderate to Severe Chronic Pain Due to Osteoarthritis of the Knee
Interventions
Cebranopadol (GRT6005) Low-Dose Range, Cebranopadol (GRT6005) High-Dose Range, Placebo, Oxycodone CR
Drug
Lead sponsor
Tris Pharma, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
619 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
83
States / cities
Birmingham, Alabama • Huntsville, Alabama • Phoenix, Arizona + 74 more
Source: ClinicalTrials.gov public record
Updated Jul 14, 2021 · Synced Sep 9, 2026, 8:30 AM EDT
Completed Not applicable Interventional Results available

A Prospective Multicenter Longitudinal Cohort Study of the Mymobility Platform

NCT03737149
View directory record Official record
Conditions
Osteoarthritis, Knee, Osteoarthritis, Hip
Interventions
mymobility with Apple Watch
Other
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
6,559 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
26
States / cities
Fremont, California • Irvine, California • Redwood City, California + 23 more
Source: ClinicalTrials.gov public record
Updated Mar 22, 2026 · Synced Sep 9, 2026, 8:30 AM EDT
Not listed Not applicable Interventional

SynerFuse Spinal Fusion and Neuromodulation Proof of Concept Study

NCT04054401
View directory record Official record
Conditions
Spinal Fusion, Radiculopathy Lumbar, Chronic Pain
Interventions
DRG Neurostimulation with Spinal Fusion
Device
Lead sponsor
SynerFuse, Inc
Other
Eligibility
21 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
2
States / cities
Mishawaka, Indiana • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 23, 2023 · Synced Sep 9, 2026, 8:30 AM EDT
Recruiting Not applicable Interventional

Effects of Non-invasive Brain Stimulation on Pain Avoidance Behavior in Chronic Pain Patients

NCT07791966
View directory record Official record
Conditions
Complex Regional Pain Syndrome (CRPS)
Interventions
transcranial alternating current stimulation (tACS)
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Sep 9, 2026, 8:30 AM EDT
Completed No phase listed Observational Results available

TARGET Post-Approval Study

NCT02800863
View directory record Official record
Conditions
Complex Regional Pain Syndrome (CRPS)
Interventions
Dorsal Root Ganglion (DRG) Stimulation (Axium™ Neurostimulator System), Dorsal Root Ganglion (DRG) Stimulation (Proclaim™ Neurostimulator System)
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
22 Years to 75 Years
Enrollment
426 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
44
States / cities
Scottsdale, Arizona • Camarillo, California • Larkspur, California + 38 more
Source: ClinicalTrials.gov public record
Updated Jul 7, 2024 · Synced Sep 9, 2026, 8:30 AM EDT
Withdrawn Phase 2Phase 3 Interventional Accepts healthy volunteers

Transcranial Magnetic Stimulation (TMS) Effects on Pain Perception

NCT00349050
View directory record Official record
Conditions
Pain, Trigeminal Neuralgia, Neuropathic Pain
Interventions
laboratory pain assessment, transcranial magnetic stimulation
Device · Procedure
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years to 60 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 29, 2012 · Synced Sep 9, 2026, 8:30 AM EDT
Completed Not applicable Interventional

Intraoperative Neuromonitoring Recording With a Novel SCS Paddle: Phase II

NCT05459324
View directory record Official record
Conditions
Chronic Pain, Neuropathic Pain, Failed Back Surgery Syndrome, Complex Regional Pain Syndromes
Interventions
HD Study Electrode
Device
Lead sponsor
Albany Medical College
Other
Eligibility
18 Years to 90 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Jul 15, 2024 · Synced Sep 9, 2026, 8:30 AM EDT
Completed Not applicable Interventional

Effects of Dry Needling Using Spinal and Peripheral Sites Versus Peripheral Sites Only

NCT02646579
View directory record Official record
Conditions
Plantar Fasciitis, Achilles Tendinitis, Patellofemoral Pain Syndrome
Interventions
Spinal and Peripheral Dry Needling, Peripheral Dry Needling
Procedure
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 17, 2019 · Synced Sep 9, 2026, 8:30 AM EDT