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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Claudication, Intermittent Clear all
Completed Phase 1 Interventional Accepts healthy volunteers

Bioequivalence Study of Once Daily PMR Compared to Twice Daily Cilostazol IR Tablets in Healthy Volunteers

NCT03864666
View directory record Official record
Conditions
Intermittent Claudication
Interventions
Cilostazol 100 mg, PMR 200 mg
Drug
Lead sponsor
Genovate Biotechnology Co., Ltd.,
Industry
Eligibility
18 Years to 45 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Springfield, Missouri
Source: ClinicalTrials.gov public record
Updated May 13, 2019 · Synced Jul 21, 2026, 7:11 AM EDT
Terminated Not applicable Interventional Results available

Supervised Treadmill Exercise and Ranolazine for Intermittent Claudication of Lower Extremities

NCT00914316
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Ranolazine, Placebo
Drug
Lead sponsor
Corewell Health East
Other
Eligibility
40 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 8, 2017 · Synced Jul 21, 2026, 7:11 AM EDT
Completed Not applicable Interventional

Optimizing Impact of Manual Therapy on Lumbar Spinal Stenosis

NCT06023498
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
Manual Therapy and Exercise, Intramuscular Electroacupuncture
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
50 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Orlando, Florida • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Jul 21, 2026, 7:11 AM EDT
Completed Phase 2 Interventional

Efficacy and Safety of HMR1766 in Patients With Fontaine Stage II Peripheral Arterial Disease

NCT00443287
View directory record Official record
Conditions
Intermittent Claudication
Interventions
ataciguat (HMR1766), placebo, cilostazol
Drug
Lead sponsor
Sanofi
Industry
Eligibility
40 Years and older
Enrollment
553 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Bridgewater, New Jersey
Source: ClinicalTrials.gov public record
Updated May 16, 2018 · Synced Jul 21, 2026, 7:11 AM EDT
Completed Phase 1 Interventional

EW-A-401 to Treat Intermittent Claudication

NCT00080392
View directory record Official record
Conditions
Intermittent Claudication, Arteriosclerosis
Interventions
DNA Plasmid Vector, EW-A-401 DNA Plasmid Vector
Drug
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
21 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2011
U.S. locations
3
States / cities
Birmingham, Alabama • Bethesda, Maryland • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 11, 2019 · Synced Jul 21, 2026, 7:11 AM EDT
Completed No phase listed Observational

Comparison of Prosthetic Femoropopliteal Bypass Versus Viabahn Endoprosthesis for Treatment of Symptomatic Femoral Artery Occlusion

NCT00962897
View directory record Official record
Conditions
Atherosclerosis, Lower Extremity Ischemia, Claudication, Rest Pain
Interventions
Femoral-popliteal bypass, Stent-graft placement
Procedure
Lead sponsor
Texas Vascular Associates
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 19, 2009 · Synced Jul 21, 2026, 7:11 AM EDT
Completed Not applicable Interventional Results available

The MiDAS ENCORE Study

NCT02093520
View directory record Official record
Conditions
Spinal Stenosis, Lumbar Region, With Neurogenic Claudication
Interventions
MILD Procedure, Epidural Steroid Injection
Procedure · Drug
Lead sponsor
Vertos Medical, Inc.
Industry
Eligibility
65 Years and older
Enrollment
302 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
12
States / cities
Chula Vista, California • Fresno, California • Murrieta, California + 9 more
Source: ClinicalTrials.gov public record
Updated Dec 5, 2017 · Synced Jul 21, 2026, 7:11 AM EDT
Active, not recruiting Phase 1 Interventional

The Effects of ATLAS Therapy on Nitric Oxide Bioavailability in Patients With Intermittent Claudication

NCT04800692
View directory record Official record
Conditions
Claudication, Intermittent, Peripheral Artery Disease, Peripheral Vascular Diseases
Interventions
Tetrahydrobiopterin 10 mg/kg, Tetrahydrobiopterin 20 mg/kg, L-Ascorbate, L-Arginine
Drug
Lead sponsor
Louis Messina
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Jul 21, 2026, 7:11 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Pharmacokinetic Study of Once Daily PMR Compared to Twice Daily Cilostazol IR Tablets in Healthy Volunteers

NCT03480321
View directory record Official record
Conditions
Intermittent Claudication
Interventions
Cilostazol 100 mg, PMR 150 mg, PMR 200 mg
Drug
Lead sponsor
Genovate Biotechnology Co., Ltd.,
Industry
Eligibility
18 Years to 45 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Springfield, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 9, 2018 · Synced Jul 21, 2026, 7:11 AM EDT
Completed Not applicable Interventional

The Use of Fish Oil to Reduce Inflammation Caused by a Peripheral Vascular Intervention

NCT02096757
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Pro-Omega, Pro-Omega Placebo
Dietary Supplement · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
40 Years to 90 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 17, 2020 · Synced Jul 21, 2026, 7:11 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Bioequivalency Study of 100 mg Cilostazol Tablets Under Fasting Conditions

NCT00602173
View directory record Official record
Conditions
Intermittent Claudication
Interventions
Cilostazol
Drug
Lead sponsor
Roxane Laboratories
Industry
Eligibility
18 Years to 45 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jan 22, 2018 · Synced Jul 21, 2026, 7:11 AM EDT
Terminated No phase listed Observational

FIRE-PAD: Functional Improvement Through Revascularization of the Extremities for Peripheral Arterial Disease

NCT00274157
View directory record Official record
Conditions
Peripheral Vascular Disease
Interventions
Behavior, diet control, smoking cessation, exercize
Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
40 Years to 85 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 26, 2008 · Synced Jul 21, 2026, 7:11 AM EDT
Not listed Phase 1 Interventional

Autologous CD34+ Stem Cell Injection for Severe Intermittent Claudication (Leg Pain)

NCT00311805
View directory record Official record
Conditions
Peripheral Artery Disease, Severe Intermittent Claudication
Interventions
Autologous Stem Cells (CD34+)
Biological
Lead sponsor
Losordo, Douglas, M.D.
Individual
Eligibility
21 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2006
U.S. locations
2
States / cities
Birmingham, Alabama • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 30, 2015 · Synced Jul 21, 2026, 7:11 AM EDT
Not listed Phase 2 Interventional

Treatment of Claudication With a Peristaltic Pulse Pneumatic Device

NCT01007604
View directory record Official record
Conditions
Intermittent Claudication
Interventions
Peristaltic pulse PCD, Exercise and lifestyle counseling
Device · Other
Lead sponsor
White River Junction Veterans Affairs Medical Center
Federal
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
White River Junction, Vermont
Source: ClinicalTrials.gov public record
Updated Nov 3, 2009 · Synced Jul 21, 2026, 7:11 AM EDT
Not listed Phase 1 Interventional Accepts healthy volunteers

PET/MRI in the Diagnosis of Chronic Pain

NCT03556137
View directory record Official record
Conditions
Neuropathic Pain, Nociceptive Pain, Mixed Pain (Nociceptive and Neuropathic), Spinal Pain, Radiculopathy, Myelopathy, Neurogenic Claudication
Interventions
[18F]FTC-146
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
190 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jul 19, 2023 · Synced Jul 21, 2026, 7:11 AM EDT
Completed Phase 1 Interventional

Saving Life and Limb: FES for the Elderly With PAD

NCT02384980
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
FES (Gait MyoElectric Stimulator)
Device
Lead sponsor
MultiCare Health System Research Institute
Other
Eligibility
50 Years to 85 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Aug 15, 2016 · Synced Jul 21, 2026, 7:11 AM EDT
Completed Not applicable Interventional Results available

Evaluation of the GORE TIGRIS Vascular Stent

NCT01576055
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
TIGRIS Vascular Stent, BARD LifeStent
Device
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
21 Years and older
Enrollment
267 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
34
States / cities
Mobile, Alabama • Little Rock, Arkansas • Oceanside, California + 30 more
Source: ClinicalTrials.gov public record
Updated Oct 8, 2017 · Synced Jul 21, 2026, 7:11 AM EDT
Recruiting Not applicable Interventional

EVERO Drug-coated Balloon (DCB) Randomized Trial

NCT07144150
View directory record Official record
Conditions
Peripheral Vascular Disease, Peripheral Arterial Disease
Interventions
Evero DCB, Paclitaxel DCB
Combination Product
Lead sponsor
Cook Research Incorporated
Industry
Eligibility
18 Years and older
Enrollment
410 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
5
States / cities
Gainesville, Florida • Jacksonville, Florida • Miami, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Jul 21, 2026, 7:11 AM EDT
Completed Phase 1 Interventional Results available

A New Heat Therapy Device for Home-based Leg Heating in Patients With Lower-extremity Peripheral Artery Disease

NCT05335161
View directory record Official record
Conditions
Peripheral Arterial Disease, Intermittent Claudication
Interventions
Home-based leg heat therapy
Device
Lead sponsor
Purdue University
Other
Eligibility
60 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 14, 2025 · Synced Jul 21, 2026, 7:11 AM EDT
Completed Phase 1 Interventional

Magnetic Resonance Imaging to Detect Blood Vessel Inflammation in Patients Undergoing Peripheral Balloon Angioplasty

NCT00004549
View directory record Official record
Conditions
Atherosclerosis, Peripheral Vascular Disease
Interventions
Magnetic resonance imaging
Procedure
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2002
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Jul 21, 2026, 7:11 AM EDT
Not listed No phase listed Observational

Hyperspectral Imaging Pre and Post Endovascular Intervention

NCT00768495
View directory record Official record
Conditions
Chronic Limb Ischemia, Non-Healing Ulcers
Interventions
Not listed
Lead sponsor
HyperMed
Industry
Eligibility
50 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Falls Church, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 3, 2009 · Synced Jul 21, 2026, 7:11 AM EDT
Completed Phase 2 Interventional Results available

A Phase 2 Study of the Effects of Sapropterin Dihydrochloride on Symptomatic Peripheral Arterial Disease

NCT00403494
View directory record Official record
Conditions
Intermittent Claudication
Interventions
Placebo, Sapropterin Dihydrochloride
Other · Drug
Lead sponsor
BioMarin Pharmaceutical
Industry
Eligibility
40 Years to 80 Years
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
17
States / cities
Scottsdale, Arizona • Sacramento, California • San Diego, California + 14 more
Source: ClinicalTrials.gov public record
Updated Jan 6, 2021 · Synced Jul 21, 2026, 7:11 AM EDT
Completed Not applicable Interventional Results available

VISIBILITY™ Iliac Study

NCT01402700
View directory record Official record
Conditions
Peripheral Arterial Disease, Claudication
Interventions
Visi-Pro™ Balloon Expandable Stent System
Device
Lead sponsor
Medtronic Endovascular
Industry
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Teaneck, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 6, 2018 · Synced Jul 21, 2026, 7:11 AM EDT
Completed Phase 2 Interventional

Trial of VLTS-589 in Subjects With Intermittent Claudication

NCT00068133
View directory record Official record
Conditions
Intermittent Claudication, Peripheral Vascular Disease
Interventions
Plasmid based Gene Transfer product-VLTS-589
Genetic
Lead sponsor
Valentis
Industry
Eligibility
40 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
20
States / cities
Birmingham, Alabama • Phoenix, Arizona • Beverly Hills, California + 17 more
Source: ClinicalTrials.gov public record
Updated Jun 23, 2005 · Synced Jul 21, 2026, 7:11 AM EDT