- Conditions
- Smith-Lemli-Opitz Syndrome
- Interventions
- Cholesterol Suspension, CRH, Cholesterol
- Drug
- Lead sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- NIH
- Eligibility
- Not listed
- Enrollment
- 130 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 1998
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland
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Showing 25–44
of 20
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Cleft Palate, Cleft Lip and Palate
- Interventions
- Book-Sharing for Toddlers with Clefts (BOOST)
- Behavioral
- Lead sponsor
- Seattle Children's Hospital
- Other
- Eligibility
- 20 Months to 32 Months
- Enrollment
- 320 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2028
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Cleft Palate
- Interventions
- Polysomnography
- Procedure
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 6 Years to 15 Years
- Enrollment
- 82 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2006 – 2011
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Cleft Palate, Cleft Lip
- Interventions
- Static Images and Facial Videos
- Other
- Lead sponsor
- Tufts University
- Other
- Eligibility
- 0 Months to 21 Years
- Enrollment
- 48 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2025
- U.S. locations
- 2
- States / cities
- Boston, Massachusetts • Chapel Hill, North Carolina
- Conditions
- Cleft Palate Children
- Interventions
- Ultrasound-guided bilateral suprazygomatic maxillary nerve block, Local anesthetic infiltration of the palate
- Procedure
- Lead sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
- Other
- Eligibility
- 9 Months to 2 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2025
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Cleft Lip and Palate
- Interventions
- Intervention group (DBM/BMP), Control group(autologous ICBG)
- Drug
- Lead sponsor
- The University of Texas Health Science Center, Houston
- Other
- Eligibility
- 6 Years to 15 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2028
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Renal Cell Carcinoma, Hepatocellular Carcinoma, Colorectal Carcinoma
- Interventions
- skin punch biopsy
- Procedure
- Lead sponsor
- Dartmouth-Hitchcock Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 4 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2013
- U.S. locations
- 2
- States / cities
- Lebanon, New Hampshire • White River Junction, Vermont
- Conditions
- Cleft Palate Children, Speech Sound Disorder
- Interventions
- Speech therapy via teleprace, Face-to-face speech therapy
- Behavioral
- Lead sponsor
- Texas Tech University Health Sciences Center
- Other
- Eligibility
- 5 Years to 11 Years
- Enrollment
- 64 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 1
- States / cities
- Lubbock, Texas
- Conditions
- Post-operative Pain, Opioid Use, Cleft Palate
- Interventions
- Quadratus lumborum block, Local anesthetic infiltration
- Procedure
- Lead sponsor
- Medical University of South Carolina
- Other
- Eligibility
- 6 Years to 18 Years
- Enrollment
- 46 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina
- Conditions
- Cleft Lip, Cleft Palate
- Interventions
- Furlow double z-plasty palatoplasty palate repair, Von Langenbeck palatoplasty palate repair
- Procedure
- Lead sponsor
- University of Florida
- Other
- Eligibility
- Not listed
- Enrollment
- 475 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1996 – 2007
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Cleft Lip, Scarring, Cleft Palate
- Interventions
- Botulinum Toxin Type A, Normal Saline Injection
- Drug
- Lead sponsor
- The University of Texas Health Science Center, Houston
- Other
- Eligibility
- Up to 6 Months
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2020
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Blepharocheilodontic Syndrome
- Interventions
- Not listed
- Lead sponsor
- Ohio State University
- Other
- Eligibility
- Not listed
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2040
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Cleft Lip and Palate
- Interventions
- Maxillary Protraction, Orthognathic Surgery
- Procedure
- Lead sponsor
- University of Southern California
- Other
- Eligibility
- 11 Years to 21 Years
- Enrollment
- 117 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2021
- U.S. locations
- 2
- States / cities
- Los Angeles, California • Seattle, Washington
- Conditions
- Toothbrushing, Gingivitis, Cleft Lip and Palate
- Interventions
- Toothbrush
- Device
- Lead sponsor
- Children's Hospital Los Angeles
- Other
- Eligibility
- 6 Years to 20 Years
- Enrollment
- 198 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Mouth Abnormalities, Cleft Palate, Birth Defect
- Interventions
- Ropivacaine, Sham Comparator
- Drug · Other
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 3 Months to 5 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2027
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Cleft Lip, Cleft Palate
- Interventions
- Not listed
- Lead sponsor
- Children's Healthcare of Atlanta
- Other
- Eligibility
- Not listed
- Enrollment
- 1,295 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2009
- U.S. locations
- 1
- States / cities
- Atlanta, Georgia
- Conditions
- Cleft Palate
- Interventions
- Intensive Feedback, Routine Feedback
- Behavioral
- Lead sponsor
- Children's Hospital Medical Center, Cincinnati
- Other
- Eligibility
- Not listed
- Enrollment
- 7 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2018
- U.S. locations
- 5
- States / cities
- Phoenix, Arizona • Durham, North Carolina • Cincinnati, Ohio + 2 more
- Conditions
- Cleft Palate
- Interventions
- Not listed
- Lead sponsor
- University of California, Davis
- Other
- Eligibility
- 1 Year to 10 Years
- Enrollment
- 88 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2015
- U.S. locations
- 1
- States / cities
- Sacramento, California
- Conditions
- Cleft Palate, Pain, Postoperative Care, Perioperative Care, Children
- Interventions
- Methadone hydrochloride, Fentanyl/Hydromorphone
- Drug
- Lead sponsor
- Duke University
- Other
- Eligibility
- 6 Months to 4 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Otitis Media, Cleft Palate
- Interventions
- palatoplasty
- Procedure
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- Up to 15 Months
- Enrollment
- 83 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2020
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania