Independent directory Public ClinicalTrials.gov records United States
Clear filters
ClinicalTrials.gov public records Last synced Jul 22, 2026, 10:44 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–16 of 16 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Active, not recruiting Phase 4 Interventional

Evaluation of Trigeminal Nerve Blockade

NCT03632044
Conditions
Mouth Abnormalities, Cleft Palate, Birth Defect
Interventions
Ropivacaine, Sham Comparator
Drug · Other
Lead sponsor
University of Florida
Other
Eligibility
3 Months to 5 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
1
States / cities
Gainesville, Florida
Recruiting Phase 4 Interventional

Ketorolac in Palatoplasty

NCT04771156
Conditions
Cleft Lip and Palate
Interventions
Ketorolac, Placebo
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
6 Months and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Houston, Texas
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Botulinum Toxin to Improve Cosmesis of Primary Cleft Lip Repair

NCT02247193
Conditions
Cleft Lip, Scarring, Cleft Palate
Interventions
Botulinum Toxin Type A, Normal Saline Injection
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
Up to 6 Months
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
1
States / cities
Houston, Texas
Conditions
Otitis Media, Cleft Palate
Interventions
palatoplasty
Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
Up to 15 Months
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Recruiting Not applicable Interventional

QL vs LAI for Palatoplasty

NCT06420336
Conditions
Post-operative Pain, Opioid Use, Cleft Palate
Interventions
Quadratus lumborum block, Local anesthetic infiltration
Procedure
Lead sponsor
Medical University of South Carolina
Other
Eligibility
6 Years to 18 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Cleft Palate
Interventions
Oral acetaminophen, Ofirmev®, Opioid only
Drug
Lead sponsor
Loma Linda University
Other
Eligibility
5 Months to 5 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Loma Linda, California
Conditions
Cleft Palate
Interventions
Not listed
Lead sponsor
University of California, Davis
Other
Eligibility
1 Year to 10 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2015
U.S. locations
1
States / cities
Sacramento, California
Conditions
Cleft Palates
Interventions
Unasyn, saline solution
Drug · Other
Lead sponsor
Joseph Losee
Other
Eligibility
3 Months to 18 Years
Enrollment
224 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Cleft Palate
Interventions
Amoxicillin
Drug
Lead sponsor
University of Florida
Other
Eligibility
1 Month to 60 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
2
States / cities
Gainesville, Florida
Completed No phase listed Observational Accepts healthy volunteers

Sleep and Behavior in Children With Cleft Palate

NCT01046591
Conditions
Cleft Palate
Interventions
Polysomnography
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
6 Years to 15 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Cleft Palate
Interventions
Not listed
Lead sponsor
University of Pittsburgh
Other
Eligibility
Up to 24 Months
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Cleft Lip, Cleft Palate
Interventions
Furlow double z-plasty palatoplasty palate repair, Von Langenbeck palatoplasty palate repair
Procedure
Lead sponsor
University of Florida
Other
Eligibility
Not listed
Enrollment
475 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2007
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Cleft Lip and Cleft Palate, Cleft Lip Palate, Cleft Lip and/or Palate, Cleft Palate, Cleft Palate Children, Cleft Palates, Cleft Palate Repair
Interventions
Early intervention for language, articulation and palatal function skills
Behavioral
Lead sponsor
Old Dominion University
Other
Eligibility
6 Months to 12 Months
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Norfolk, Virginia
Conditions
Cleft Palate
Interventions
IV acetaminophen, Placebo
Drug
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Cleft Lip, Cleft Palate
Interventions
Not listed
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
Not listed
Enrollment
1,295 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Cleft Palate, Pain, Postoperative Care, Perioperative Care, Children
Interventions
Methadone hydrochloride, Fentanyl/Hydromorphone
Drug
Lead sponsor
Duke University
Other
Eligibility
6 Months to 4 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Durham, North Carolina