Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 7, 2026, 3:16 AM EDT

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Showing 1–24 of 65 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Completed Phase 1 Interventional Accepts healthy volunteers

Galantamine Effects on Cognitive Function in Marijuana Users

NCT00969696
Conditions
Memory
Interventions
Placebo, Galantamine
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 55 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
West Haven, Connecticut
Conditions
Cognitive Ability, General, Achievement
Interventions
Physical Activity
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
8 Years to 9 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
4
States / cities
Urbana, Illinois
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cognitive Remediation to Improve Mobility in Sedentary Seniors

NCT02567227
Conditions
Mobility Limitation, Motor Activity, Difficulty Walking, Cognitive Ability General
Interventions
Cognitive Remediation, Active Control
Other
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
70 Years and older
Enrollment
383 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
The Bronx, New York
Conditions
Mild Cognitive Impairment, Memory Loss
Interventions
Transcranial magnetic stimulation
Device
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2027
U.S. locations
1
States / cities
Omaha, Nebraska
Conditions
Suicidal Ideation
Interventions
Problem Solving Therapy (PST) plus EUC
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Palo Alto, California
Conditions
Cognitive Ability, General
Interventions
SageXtra, Placebo
Dietary Supplement
Lead sponsor
ESM Technologies, LLC
Industry
Eligibility
40 Years to 60 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
College Station, Texas
Conditions
Physical Inactivity, Aging, Cognitive Ability, Behavior Change
Interventions
Text Messaging Intervention
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
40 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Not listed Not applicable Interventional Accepts healthy volunteers

TDCS to Improve Motivation and Memory in Elderly (TIME)

NCT04268186
Conditions
Motivation
Interventions
Direct tDCS, Indirect tDCS, Personalized tDCS, Sham tDCS
Device
Lead sponsor
Northeastern University
Other
Eligibility
65 Years to 80 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Fibromyalgia
Interventions
Esreboxetine
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 65 Years
Enrollment
89 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
7
States / cities
Destin, Florida • Fort Walton Beach, Florida • Ann Arbor, Michigan + 4 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Intervention Comparative Effectiveness for Adult Cognitive Training

NCT03141281
Conditions
Cognitive Aging
Interventions
BrainHQ, Rise of Nations, IADL Training, Active Control
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
65 Years and older
Enrollment
238 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Tallahassee, Florida
Recruiting Not applicable Interventional Accepts healthy volunteers

Investigating the Effects of Beef Consumption on Cognitive and Brain Health

NCT06690892
Conditions
Dietary Intervention, Dietary Proteins, Dietary Assessment, Cognitive Ability, General
Interventions
Ready-to-eat beef in frozen, 5-oz packages, Ready-to-eat beef in frozen, 1-oz packages
Dietary Supplement
Lead sponsor
University of Nebraska Lincoln
Other
Eligibility
19 Years to 24 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Lincoln, Nebraska
Conditions
Cognitive/Functional Effects, Depression, Fatigue, Unspecified Adult Solid Tumor, Protocol Specific
Interventions
modafinil, cognitive assessment, psychosocial assessment and care, quality-of-life assessment
Drug · Procedure
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2004
U.S. locations
1
States / cities
Charlottesville, Virginia
Completed Not applicable Interventional Accepts healthy volunteers

Effects of PeptiSleep on Sleep Quality in Healthy Adults

NCT07258433
Conditions
Sleep, Wearable Technology, Cortisol, Healthy Participants, Cognitive Abilities
Interventions
PeptiSleep, Micro-crystalline cellulose
Dietary Supplement
Lead sponsor
Nuritas Ltd
Industry
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Wilmington, Delaware
Recruiting No phase listed Observational Accepts healthy volunteers

Automated IADL Sensing to Refine Measurement of Older Adult Daily Activity

NCT07585864
Conditions
Cognitive Ability General, Functional Abilities
Interventions
Not listed
Lead sponsor
University of Pittsburgh
Other
Eligibility
75 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Alzheimer Disease, Alzheimer's Disease (Incl Subtypes), Preclinical Alzheimer's Disease, Prodromal Alzheimer's Disease, Mild Cognitive Impairment, Normal Cognition
Interventions
Not listed
Lead sponsor
Novoic Limited
Industry
Eligibility
50 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Santa Ana, California
Conditions
Multiple Sclerosis, Cognitive Ability, General
Interventions
Ginkgo biloba, Placebo
Drug
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
2
States / cities
Portland, Oregon • Seattle, Washington
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Enhancing Cognitive Control Abilities Using Mobile Technology in a Senior Living Community

NCT04905849
Conditions
Aging, Cognitive Change
Interventions
Adaptive Cognitive Control Trainer (ACCT), Active Control App
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
50 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
San Francisco, California
Conditions
Opioid Use Disorder, Cognitive Ability General
Interventions
Smartphone based cognitive tasks
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
55 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Parkinson's Disease, Freezing of Gait, Cognitive Ability, General
Interventions
Droxidopa, sugar pill
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
30 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
2
States / cities
Chicago, Illinois • West Bloomfield, Michigan
Completed Early Phase 1 Interventional Accepts healthy volunteers

Multidimensional Assessment and Intervention for Elder Self-Neglect

NCT00901706
Conditions
Self-Neglect, Cognitive Ability, General, Geriatric Disorder
Interventions
Comprehensive Geriatric Assessment and APS Usual Care, APS usual care
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
65 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Houston, Texas
Conditions
Mild Cognitive Impairment, Dementia
Interventions
Resources and Activities for Life Long Independence (RALLI), Social Walking program (SW)
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
70 Years and older
Enrollment
181 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Seattle, Washington
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Acute Pain on Motor Learning in Young vs Older Adults

NCT05471557
Conditions
Aging, Pain, Acute, Cognitive Decline, Motor Activity
Interventions
pain delivery
Procedure
Lead sponsor
University of Delaware
Other
Eligibility
18 Years to 85 Years
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Newark, Delaware
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

ACTIVE: Advanced Cognitive Training for Independent and Vital Elderly

NCT00298558
Conditions
Aging, Healthy
Interventions
Cognitive Training
Behavioral
Lead sponsor
Carelon Research
Other
Eligibility
65 Years and older
Enrollment
2,832 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1998 – 2010
U.S. locations
7
States / cities
Birmingham, Alabama • Indianapolis, Indiana • Baltimore, Maryland + 4 more
Recruiting Not applicable Interventional Accepts healthy volunteers

Unconscious Mind Training

NCT07597603
Conditions
Memory Encoding, Memory, Behavior Change Interventions, Habits
Interventions
Intervention H22
Behavioral
Lead sponsor
Dream Video LLC
Other
Eligibility
10 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2028
U.S. locations
1
States / cities
Naples, Florida