- Conditions
- Unconsciousness, Apnea, Postanesthetic, Sedative Overdose, Hypoxemia
- Interventions
- Titrate propofol monotherapy infusion to effect
- Procedure
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 2,780 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
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Showing 25–48
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matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Conscious Sedation
- Interventions
- SEDASYS System
- Device
- Lead sponsor
- Ethicon Endo-Surgery
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 51 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- Toledo, Ohio
- Conditions
- Undesired Intrauterine Pregnancy, First Trimester Pregnancy
- Interventions
- Intravenous moderate sedation versus oral medication
- Drug
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 16 Years to 55 Years · Female only
- Enrollment
- 18 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2007 – 2008
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Conscious Sedation Failure During Procedure
- Interventions
- ketamine and midazolam, etomidate, fentanyl, and lidocaine
- Drug
- Lead sponsor
- Drexel University College of Medicine
- Other
- Eligibility
- 5 Years to 18 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2006 – 2008
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Critical Illness
- Interventions
- Bispectral Index (BIS) Monitor
- Device
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2011
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Enhanced Recovery Pathway, Endoscopy
- Interventions
- Ondansetron 4 MG, Lactated Ringers, Intravenous, Early Mobilization, Early PO Intake
- Drug · Other
- Lead sponsor
- Northwestern University
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Colonoscopy, Endoscopy, Digestive System, Conscious Sedation
- Interventions
- Computer-Assisted Personalized Sedation (CAPS) Device (SEDASYS® System), benzodiazepines and opioid sedation
- Device · Other
- Lead sponsor
- Ethicon Endo-Surgery
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 1,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007
- U.S. locations
- 7
- States / cities
- Washington D.C., District of Columbia • Fayetteville, North Carolina • Winston-Salem, North Carolina + 4 more
- Conditions
- Dental Caries
- Interventions
- Isolite System
- Device
- Lead sponsor
- The University of Texas Health Science Center at San Antonio
- Other
- Eligibility
- 4 Years to 7 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2013
- U.S. locations
- 2
- States / cities
- San Antonio, Texas
- Conditions
- Outpatient Colonoscopy for Colorectal Cancer Screening or for Symptoms Suggestive of Colonic Diseases
- Interventions
- Colonoscopy Force Monitor
- Device
- Lead sponsor
- Artann Laboratories
- Industry
- Eligibility
- 30 Years to 75 Years
- Enrollment
- 102 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 3
- States / cities
- Washington D.C., District of Columbia • Chevy Chase, Maryland • Philadelphia, Pennsylvania
- Conditions
- Mental Function
- Interventions
- Propofol for fMRI, Dexmedetomidine for fMRI, Dorsolateral prefrontal cortex (DLPFC) pulsation, Anterior insular cortex (AIC) pulsation, Central thalamus (CT) pulsation
- Procedure · Device
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 18 Years to 40 Years
- Enrollment
- 168 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2030
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Procedural Sedation, Regional Anesthesia Block, Orthopedic Surgery
- Interventions
- Fospropofol disodium, Placebo + Midazolam, Fentanyl
- Drug
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 13 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011
- U.S. locations
- 1
- States / cities
- Phoenix, Arizona
- Conditions
- Conscious Sedation, Bronchoscopy
- Interventions
- Not listed
- Lead sponsor
- Tufts Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 33 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2019
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Undesired Pregnancy
- Interventions
- oxycodone + lorazepam versus fentanyl + midazolam
- Drug
- Lead sponsor
- Planned Parenthood League of Massachusetts
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 132 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2006 – 2007
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Minor Procedural Pain
- Interventions
- Lazanda
- Drug
- Lead sponsor
- Defense and Veterans Center for Integrative Pain Management
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 23 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- Fort Bragg, North Carolina
- Conditions
- Dysphagia, GERD, Abdominal Pain
- Interventions
- Lidocaine, Placebo
- Drug
- Lead sponsor
- Brooke Army Medical Center
- Federal
- Eligibility
- 18 Years to 89 Years
- Enrollment
- 106 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- Fort Sam Houston, Texas
- Conditions
- Stroke, Brain Ischemia, Vasospasm, Intracranial, Hemorrhage, Intracranial
- Interventions
- Dexmedetomidine, Fentanyl, Midazolam
- Drug
- Lead sponsor
- University Hospitals Cleveland Medical Center
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 7 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2021
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Conscious Sedation
- Interventions
- Child life intervention, Music listening
- Other
- Lead sponsor
- Children's Hospital of Michigan
- Other
- Eligibility
- 3 Years to 15 Years
- Enrollment
- 63 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- Detroit, Michigan
- Conditions
- Anesthesia, Psychomotor Status
- Interventions
- Not listed
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 68 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2020
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Nitrous Oxide
- Interventions
- Nitrous Oxide
- Drug
- Lead sponsor
- University of Arkansas
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Little Rock, Arkansas
- Conditions
- Blood Pressure, Dental Anxiety
- Interventions
- Intravenous Sedatives with or Without Analgesia, No IV sedation
- Drug
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Heavy Uterine Bleeding
- Interventions
- Uterine Ablation
- Device
- Lead sponsor
- Female Pelvic Medicine & Urogynecology Institute of Michigan
- Other
- Eligibility
- 30 Years to 60 Years · Female only
- Enrollment
- 21 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2005 – 2009
- U.S. locations
- 1
- States / cities
- Grand Rapids, Michigan
- Conditions
- Vasectomy, Sedation
- Interventions
- midazolam by nasal atomizer, intravenous midazolam
- Device · Drug
- Lead sponsor
- University of Tennessee Graduate School of Medicine
- Other
- Eligibility
- 18 Years to 85 Years · Male only
- Enrollment
- 35 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2020
- U.S. locations
- 1
- States / cities
- Knoxville, Tennessee
- Conditions
- Anesthesia, Endoscopy, Colonoscopy, Conscious Sedation
- Interventions
- midazolam alone
- Drug
- Lead sponsor
- Greg S Cohen MD LLC
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 300 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2023
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Childrens 0 to 18 Years of Age Who Require Moderate Sedation
- Interventions
- Not listed
- Lead sponsor
- Akron Children's Hospital
- Other
- Eligibility
- Up to 18 Years
- Enrollment
- 416 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- Akron, Ohio