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ClinicalTrials.gov public records Last synced Nov 7, 2026, 12:52 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 26 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Contact Lens Comfort Clear all

Conditions: Contact Lens Complication
Interventions: Acuvue® Oasys® Lenses (senofilcon A), 30-Day Bausch + Lomb PureVision (balafilcon A), Clariti® 1-Day (Somofilcon A); Device
Lead sponsor: ORA, Inc.; Industry
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014
U.S. locations: 1
States / cities: Andover, Massachusetts

Conditions: Contact Lens Comfort and Successful Refitting, Presbyopia
Interventions: DAILIES TOTAL1 Multifocal (delefilcon A); Device
Lead sponsor: Gordon Schanzlin New Vision; Other
Eligibility: 40 Years and older
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Contact Lens Comfort
Interventions: senofilcon A; Device
Lead sponsor: Ohio State University; Other
Eligibility: 8 Years and older
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Dry Eye, Contact Lens Complication
Interventions: DT1 Sphere Contact Lenses; Device
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years to 40 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 4
States / cities: Birmingham, Alabama • Pittsburg, Kansas • Granville, Ohio + 1 more

Conditions: Contact Lens Comfort and Successful Refitting
Interventions: Dailies total 1 contact lenses; Device
Lead sponsor: Southern College of Optometry; Other
Eligibility: 18 Years to 40 Years
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Eye Strain
Interventions: Total 30 Contact Lens; Device
Lead sponsor: Tauber Eye Center; Other
Eligibility: 18 Years to 40 Years
Enrollment: 35 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Kansas City, Missouri

Conditions: Ametropia
Interventions: senofilcon A toric, alphafilcon A toric; Device
Lead sponsor: Johnson & Johnson Vision Care, Inc.; Industry
Eligibility: 18 Years to 45 Years
Enrollment: 89 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008
U.S. locations: 7
States / cities: Jacksonville, Florida • Orlando, Florida • Morrow, Georgia + 4 more

Conditions: Comfort, Vision and Wear Time
Interventions: New PEG based artificial tear, Optive; Drug
Lead sponsor: Bp Consulting, Inc; Network
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: New York, New York

Conditions: Contact Lens Comfort
Interventions: Precision 7 contact lenses; Device
Lead sponsor: Southern College of Optometry; Other
Eligibility: 18 Years to 40 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Myopia
Interventions: Multi-Purpose Disinfecting Solution (OPTI-FREE RepleniSH), Contact Lenses; Device
Lead sponsor: Alcon Research; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 114 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008
U.S. locations: 1
States / cities: Fort Worth, Texas

Conditions: Dry Eye, Contact Lens Complication, Contact Lenses
Interventions: T30 Contact lenses; Device
Lead sponsor: Southern College of Optometry; Other
Eligibility: 18 Years to 40 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Patient Comfort, Lens Cleanliness
Interventions: new MPS, opti-free express no rub MPS; Drug
Lead sponsor: Innovative Medical; Industry
Eligibility: 18 Years and older
Enrollment: 20 participants
Timeline: Ends 2008
U.S. locations: 1
States / cities: Fort Worth, Texas

Conditions: Vision Correction
Interventions: senofilcon A toric, balafilcon A toric; Device
Lead sponsor: Johnson & Johnson Vision Care, Inc.; Industry
Eligibility: 18 Years to 45 Years
Enrollment: 276 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008
U.S. locations: 19
States / cities: North Little Rock, Arkansas • Mission Viejo, California • Colorado Springs, Colorado + 16 more

Conditions: Contact Lens Solution Toxicity
Interventions: RevitaLens, OptiFree PureMoist; Other
Lead sponsor: Hom, Milton M., OD, FAAO; Individual
Eligibility: 18 Years and older
Enrollment: 54 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2014
U.S. locations: 3
States / cities: Azusa, California • Morrow, Georgia • Louisville, Kentucky

Conditions: Corneal Staining
Interventions: Biotrue MPS, Investigational MPS; Device
Lead sponsor: Abbott Medical Optics; Industry
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010
U.S. locations: 1
States / cities: Santa Ana, California

Conditions: Contact Lens Complication, Astigmatism, Refractive Errors
Interventions: Total30 for Astigmatism Contact Lenses; Device
Lead sponsor: Southern College of Optometry; Other
Eligibility: 18 Years to 40 Years
Enrollment: 48 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 2
States / cities: Pittsburg, Kansas • Coldwater, Mississippi

Conditions: Contact Lenses, Presbyopia
Interventions: Total 30 multi foric contact lenses; Device
Lead sponsor: Southern College of Optometry; Other
Eligibility: 18 Years to 40 Years
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Contact Lens Base Curve (BC) Fit and Comfort
Interventions: Contact Lenses with 8.5 BC, Contact Lenses with 9.0 BC; Device
Lead sponsor: Johnson & Johnson Vision Care, Inc.; Industry
Eligibility: 18 Years to 45 Years
Enrollment: 72 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015
U.S. locations: 2
States / cities: Jacksonville, Florida

Conditions: Contact Lens Complication, Dry Eye
Interventions: Total30 Sphere Contact Lenses; Device
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years to 45 Years
Enrollment: 48 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 2
States / cities: Birmingham, Alabama

Conditions: Visual Acuity
Interventions: ACUVUE Oasys 1-Day, Precision 1; Device
Lead sponsor: Johnson & Johnson Vision Care, Inc.; Industry
Eligibility: 18 Years to 40 Years
Enrollment: 302 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 10
States / cities: Mission Viejo, California • Maitland, Florida • Orange Park, Florida + 7 more

Conditions: Astigmatism
Interventions: enfilcon A, senofilcon A; Device
Lead sponsor: CooperVision, Inc.; Industry
Eligibility: 18 Years to 38 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012
U.S. locations: 3
States / cities: Birmingham, Alabama • Jacksonville, Florida • Lafayette, Louisiana

Conditions: Astigmatism
Interventions: Precision1 for Astigmatism, Precision1 Sphere; Device
Lead sponsor: Kathryn Richdale; Other
Eligibility: 18 Years to 39 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Myopia, Astigmatism, Refractive Error
Interventions: OPTI-FREE RepleniSH multipurpose solution, ReNu Biotrue multipurpose solution, Silicone hydrogel contact lenses; Device
Lead sponsor: Alcon Research; Industry
Eligibility: 18 Years and older
Enrollment: 104 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010
U.S. locations: 1
States / cities: Fort Worth, Texas

Conditions: Contact Lens Complication, Astigmatism, Refractive Errors
Interventions: TOTAL30 for Astigmatism Contact Lenses; Device
Lead sponsor: Southern College of Optometry; Other
Eligibility: 18 Years to 45 Years
Enrollment: 48 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 2
States / cities: Pittsburg, Kansas • Coldwater, Mississippi

Search by objective public record fields.

A Clinical Study Comparing the Comfort of Three Commercially Available Contact Lenses

Refitting Satisfied INFUSE One-Day Multifocal Wearers to DAILIES TOTAL1 Multifocal Contact Lenses

Contact Lens Adaptation in Neophytes

Dailies Total 1 Sphere Contact Lenses

How Does DT1 Sphere Perform in Current and Successful Acuvue MAX Wearers?

To Evaluate the Performance of Total 30 (Lehifilcon A) Contact Lenses in Patients Using Digital Devices for Greater Than 8 Hours Per Day 5 Days Per Week Based on Subjective Reported Data.

Comparison of Two Toric Contact Lenses on Current Toric Wearers

Masked Comparison of a New PEG Based Artificial Tear and Optive for Comfort, Vision & Wear Time in Patients Wearing Contact Lenses

Acuvue Oaysis Contact Lens Wearers Being Refit Into P7 Contact Lenses

A Multi-Center Investigation of Patient Acceptability of OPTI-FREE RepleniSH® Multi-Purpose Disinfecting Solution (MPDS)

Total30 For Contact Lens Dropouts

Comfort and Cleaning Evaluation of Multipurpose Solutions in Contact Lens Patients

Performance of Two Silicone Hydrogel Toric Contact Lenses

Assessing Patient Comfort With Two Different Multi-Purpose Disinfecting Solutions

Short-Term Evaluation of Corneal Staining With Balafilcon A Lenses and Two Multi-Purpose Solutions

T30 for Astigmatism in Digital Device Users

Clinical Performance of Verofilcon A Toric Contact Lenses

Evaluation of 8.5 vs 9.0 Base Curve for 1-DAY ACUVUE(r) TruEye(r) Brand Contact Lenses

Total30 Sphere Contact Lenses

Evaluation of Comfort for Two Marketed Daily Disposable Contact Lenses

Clinical Comfort Evaluation of Two Marketed Spherical Contact Lenses

Toric Contact Lens Digital Performance and Comfort Study

Subjective Comfort With Multipurpose Care Solutions in Soft Contact Lens Wearers

Total30 for Astigmatism Contact Lenses