- Conditions
- Bloodloss, Surgical Procedures, Operative
- Interventions
- ecallantide, placebo
- Drug
- Lead sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
- Industry
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 276 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2010
- U.S. locations
- 21
- States / cities
- Birmingham, Alabama • Montgomery, Alabama • Aurora, Colorado + 14 more
Search Results
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Showing 1–24
of 133
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Coronary Artery Bypass Graft Surgery, Myocardial Ischemia, Reperfusion Injury, Myocardial Revascularization
- Interventions
- (MC-1) Pyridoxal-5'-phosphate
- Drug
- Lead sponsor
- Medicure
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 900 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2005
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Coronary Artery Stenosis, Myocardial Revascularization, Myocardial Ischemia
- Interventions
- Percutaneous Coronary Intervention, Coronary Artery Bypass Grafting
- Procedure
- Lead sponsor
- Ministry of Science and Higher Education, Poland
- Government
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 130 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2005
- U.S. locations
- 2
- States / cities
- Bryn Mawr, Pennsylvania • San Antonio, Texas
- Conditions
- Myocardial Infarction, Percutaneous Coronary Intervention, Coronary Artery Bypass Surgery, Heart Valve Repair or Replacement, Heart Transplant, Left Ventricular Assist Device, Chronic Stable Angina, Chronic Stable Heart Failure
- Interventions
- Text Messaging Intervention
- Behavioral
- Lead sponsor
- University of Washington
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 38 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Coronary Artery Bypass Graft Surgery, Myocardial Ischemia, Reperfusion Injury
- Interventions
- (MC-1) Pyridoxal 5'-phosphate
- Drug
- Lead sponsor
- Medicure
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 3,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2007
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Postoperative Hemorrhage
- Interventions
- hetastarch
- Drug
- Lead sponsor
- Kaiser Permanente
- Other
- Eligibility
- 20 Years to 80 Years
- Enrollment
- 330 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2005
- U.S. locations
- 1
- States / cities
- Oakland, California
- Conditions
- Procalcitonin, Coronary Artery Bypass Grafting
- Interventions
- Not listed
- Lead sponsor
- Tampa Bay Heart Foundation
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 105 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2009
- U.S. locations
- 1
- States / cities
- Clearwater, Florida
- Conditions
- Neurological Manifestations
- Interventions
- Optimizing hemodynamic and anesthetic parameters to improve cerebral perfusion
- Device
- Lead sponsor
- Atlantic Health System
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 250 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2009
- U.S. locations
- 1
- States / cities
- Morristown, New Jersey
- Conditions
- Atherosclerosis of Autologous Vein Coronary Artery Bypass Graft(s)
- Interventions
- eSVS Mesh treated saphenous vein graft, Control saphenous vein graft
- Device · Other
- Lead sponsor
- Kips Bay Medical, Inc.
- Industry
- Eligibility
- 21 Years to 85 Years
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2020
- U.S. locations
- 5
- States / cities
- Atlanta, Georgia • Gainesville, Georgia • Rochester, Minnesota + 2 more
- Conditions
- Coronary Artery Disease, Ischemic Heart Disease (IHD), Myocardial Viability
- Interventions
- Not listed
- Lead sponsor
- University of Texas Southwestern Medical Center
- Other
- Eligibility
- 20 Years to 80 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2026
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Other Surgical Procedures
- Interventions
- Surgical Video Assessments, Video Recording of CAB
- Other
- Lead sponsor
- M.D. Anderson Cancer Center
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 8 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2017
- U.S. locations
- 6
- States / cities
- Dallas, Texas • Houston, Texas • San Antonio, Texas
- Conditions
- Lung Injury, Pulmonary Complication
- Interventions
- Fraction of Inspired Oxygen
- Other
- Lead sponsor
- University of Louisville
- Other
- Eligibility
- 18 Years to 75 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- Louisville, Kentucky
- Conditions
- Surgery, Pneumonia, Surgical Site Infection
- Interventions
- Continuous Sternal Block, Opioid based analgesia
- Device · Drug
- Lead sponsor
- Halyard Health
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 647 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2012
- U.S. locations
- 8
- States / cities
- Birmingham, Alabama • Newark, Delaware • Lexington, Kentucky + 5 more
- Conditions
- Myocardial Infarction, Coronary Artery Bypass, Percutaneous Coronary Intervention, Heart Failure, Cardiac Valve Surgery
- Interventions
- RPE (usual care), GXT+THHR (intervention)
- Behavioral
- Lead sponsor
- Baystate Medical Center
- Other
- Eligibility
- 60 Years to 99 Years
- Enrollment
- 320 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 2
- States / cities
- Springfield, Massachusetts • Detroit, Michigan
- Conditions
- Coronary Artery Disease, Heart Diseases
- Interventions
- Single arterial graft, Multiple arterial grafting
- Procedure
- Lead sponsor
- Weill Medical College of Cornell University
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 4,300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2030
- U.S. locations
- 11
- States / cities
- Boulder, Colorado • Springfield, Massachusetts • Lincoln, Nebraska + 5 more
- Conditions
- Blood Glucose, Coronary Artery Bypass, Insulin, Coronary Disease
- Interventions
- LIBERAL
- Other
- Lead sponsor
- Inova Health Care Services
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2009 – 2016
- U.S. locations
- 1
- States / cities
- Falls Church, Virginia
- Conditions
- CABG Graft Integrity, CABG, Blood Flow, Transit-time Flow Measurement, Heart Disease
- Interventions
- Transit-Time Flow Measurement (TTFM)
- Device
- Lead sponsor
- Weill Medical College of Cornell University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1,242 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2032
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Coronary Artery Bypass Grafting, Mitral Valve Surgery, Low Cardiac Output Syndrome
- Interventions
- Levosimendan, Placebo
- Drug
- Lead sponsor
- Tenax Therapeutics, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 882 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 49
- States / cities
- Burlington, Alabama • Huntsville, Alabama • Sacramento, California + 41 more
- Conditions
- Coronary Artery Bypass Grafting, Heart Diseases, Heart Valve Diseases
- Interventions
- Not listed
- Lead sponsor
- Weill Medical College of Cornell University
- Other
- Eligibility
- 18 Years to 100 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1999 – 2007
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Heart Diseases, Coronary Artery Disease, Chest Pain, Stenosis Coronary, STEMI
- Interventions
- TEE probe
- Device
- Lead sponsor
- University of Pennsylvania
- Other
- Eligibility
- 18 Years to 100 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Cardiac Surgery, Coronary Artery Bypass Graft CABG, Stent, Valve Replacement
- Interventions
- Exercise Component Of Cardiac Rehabilitation (Hybrid Model) Intensity Recovery Progression Protocol (IRPP)
- Other
- Lead sponsor
- Good Shepherd Integrated Healthcare Systems
- Other
- Eligibility
- Not listed
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2021
- U.S. locations
- 1
- States / cities
- Las Vegas, Nevada
- Conditions
- Coronary Artery Bypass Graft
- Interventions
- MIB-626, Placebo
- Drug · Other
- Lead sponsor
- Brigham and Women's Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 90 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Coronary Disease, Coronary Stenosis
- Interventions
- FFR guided PCI, CABG, Resolute Integrity Stent, Resolute Onyx Stent
- Procedure · Device
- Lead sponsor
- Stanford University
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 1,500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2024
- U.S. locations
- 13
- States / cities
- Palo Alto, California • Stanford, California • Decatur, Georgia + 9 more
- Conditions
- Colchicine, Inflammation in Cardiac Surgery, Post Operative Atrial Fibrillation, Inflammatory Markers, Colchicine Adverse Reaction
- Interventions
- Colchicine (Colcrys®), Placebo
- Drug
- Lead sponsor
- Ayesha Ather
- Other
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026
- U.S. locations
- 1
- States / cities
- Lexington, Kentucky