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Showing 1–15 of 15 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Couple Dysfunction Clear all
Completed No phase listed Observational

Classification of Heart Failure With Preserved Ejection Fraction

NCT01030991
View directory record Official record
Conditions
Heart Failure With Preserved Ejection Fraction, Diastolic Heart Failure
Interventions
Not listed
Lead sponsor
Northwestern University
Other
Eligibility
21 Years and older
Enrollment
514 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 22, 2019 · Synced Jul 22, 2026, 3:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Couples Therapy to Enhance Intimacy Between Patients With Advanced or Recurrent Prostate Cancer and Their Partners

NCT00483678
View directory record Official record
Conditions
Prostate Cancer, Psychosocial Effects of Cancer and Its Treatment, Sexual Dysfunction, Sexuality and Reproductive Issues
Interventions
counseling intervention, questionnaire administration, psychosocial assessment and care
Other · Procedure
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years to 120 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2018
U.S. locations
2
States / cities
New York, New York • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 5, 2018 · Synced Jul 22, 2026, 3:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Intimacy-Enhancing Couples' Intervention for Localized Prostate Cancer

NCT01982058
View directory record Official record
Conditions
Prostate Cancer, Sexual Dysfunction and Infertility, Sexuality
Interventions
communication intervention, counseling intervention, nutrition intervention, questionnaire administration
Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
483 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2017
U.S. locations
6
States / cities
New Brunswick, New Jersey • Newark, New Jersey • Whippany, New Jersey + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 18, 2022 · Synced Jul 22, 2026, 3:16 PM EDT
Withdrawn Phase 2 Interventional

Effects of Prolonged Delivery of Nitric Oxide Gas on Plasma Reduction-Oxidation Reactions in Cardiac Surgical Patients

NCT04022161
View directory record Official record
Conditions
Cardiovascular Diseases, Oxidative Stress, Endothelial Dysfunction
Interventions
Nitrogen Gas for Inhalation, Blood withdrawal, Nitric Oxide
Drug · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced Jul 22, 2026, 3:16 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Dietary Sodium, Oxidative Stress, and Pulsatile Hemodynamics

NCT04233957
View directory record Official record
Conditions
Sodium Excess
Interventions
High Sodium, Placebo
Dietary Supplement · Other
Lead sponsor
University of Delaware
Other
Eligibility
21 Years to 45 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Nov 28, 2023 · Synced Jul 22, 2026, 3:16 PM EDT
Not yet recruiting Early Phase 1 Interventional

Coupled Gentamicin-Lactobacillus Rhamnosus in NLUTD

NCT07643974
View directory record Official record
Conditions
Spinal Cord Injury, Neurogenic Bladder (NB), Neurogenic Lower Urinary Tract Dysfunction, Multiple Sclerosis, Spina Bifida, Urinary Tract Infection(UTI)
Interventions
Gentamicin, Lactobacillus Rhamnosus GG
Drug
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Jul 22, 2026, 3:16 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Inorganic Nitrate Supplementation on Cerebrovascular Aging and Arterial Stiffness Study

NCT03617302
View directory record Official record
Conditions
Aging, Arterial Stiffness, Endothelial Dysfunction, Hypertension, Cognitive Decline
Interventions
Experimental: Nitrate-containing, Placebo: Nitrate-depleted
Drug
Lead sponsor
Gary L. Pierce, PhD
Other
Eligibility
50 Years to 79 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Jul 22, 2026, 3:16 PM EDT
Not listed No phase listed Observational

Electroencephalogram Recording in Patients With Systemic Lupus Erythematosus

NCT06378736
View directory record Official record
Conditions
Systemic Lupus Erythematosus
Interventions
Electroencephalography (EEG) signals, which will be detected noninvasively from dry scalp surface electrodes while the subjects are in a state of wakeful rest.
Other
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Apr 28, 2024 · Synced Jul 22, 2026, 3:16 PM EDT
Completed Not applicable Interventional

An Intimacy Intervention for Couples Completing Breast or Prostate Cancer

NCT04221607
View directory record Official record
Conditions
Sexual Dysfunction, Breast Cancer, Prostate Cancer
Interventions
Sensate Focus exercise
Other
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
2
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 7, 2021 · Synced Jul 22, 2026, 3:16 PM EDT
Not listed Not applicable Interventional

Assessing Psychotherapy Outcome With Feedback

NCT02023736
View directory record Official record
Conditions
Individual Psychiatric Disorder, Couple Dysfunction, Family Dysfunction
Interventions
Systemic Therapy Inventory of Change (STIC), Treatment as Usual
Other
Lead sponsor
The Family Institute at Northwestern University
Other
Eligibility
12 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
4
States / cities
Chicago, Illinois • Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 8, 2016 · Synced Jul 22, 2026, 3:16 PM EDT
Recruiting No phase listed Observational

Patient and Caregiver Perspectives on Intravesical Instillations for Urinary Symptoms

NCT07390591
View directory record Official record
Conditions
Spinal Cord Injuries, Neurogenic Lower Urinary Tract Dysfunction, Neurogenic Bladder
Interventions
Not listed
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Jul 22, 2026, 3:16 PM EDT
Recruiting Not applicable Interventional

Using Light Therapy for Mild Cognitive Impairment

NCT07651787
View directory record Official record
Conditions
Mild Cognitive Impairment (MCI), Amyloid Pathology
Interventions
Active Vielight Neuro RX-Duo device -Active transcranial photobiomodulation, Sham Vielight Neuro RX-Duo device -Sham transcranial photobiomodulation
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
55 Years to 95 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Jul 22, 2026, 3:16 PM EDT
Completed No phase listed Observational

The Role of Heart Stiff and Weak Atrium on Exercise Capacity in Patients With Hypertrophic Cardiomyopathy

NCT00074880
View directory record Official record
Conditions
Cardiomyopathy, Hypertrophic
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
Not listed
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Jul 22, 2026, 3:16 PM EDT
Withdrawn Phase 1 Interventional Accepts healthy volunteers

O2 Transport and Utilization in Health and Lung Disease

NCT04014712
View directory record Official record
Conditions
COPD, Tetrahydrobiopterin Deficiency, Oxidative Stress
Interventions
Tetrahydrobiopterin, Placebo oral tablet
Drug
Lead sponsor
University of Massachusetts, Amherst
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Amherst, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 18, 2023 · Synced Jul 22, 2026, 3:16 PM EDT
Active, not recruiting Not applicable Interventional

Psychosexual Educational Partners Program (PEPP)

NCT06253182
View directory record Official record
Conditions
Breast Cancer, Gynecologic Cancer, Sexual Dysfunction, Partner Communication
Interventions
Self-Guided PEPP Intervention Workbook, Self-Guided PEPP Education Workbook
Behavioral
Lead sponsor
The University of Tennessee, Knoxville
Other
Eligibility
18 Years to 99 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 23, 2025 · Synced Jul 22, 2026, 3:16 PM EDT