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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Completed Phase 2 Interventional Results available

Beta-blockade Effects on Memory for Cocaine Craving

NCT00830362
Conditions
Cocaine Dependence
Interventions
Propranolol, Placebo
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Smokers
Interventions
Mindfulness behavioral intervention (MT),cognitive behavioral intervention (CBT)
Behavioral
Lead sponsor
A. Eden Evins
Other
Eligibility
18 Years to 65 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Nicotine Addiction
Interventions
Cognitive Regulation of Craving, Mindfulness-Based Regulation of Craving
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 60 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
New Haven, Connecticut
Completed Not applicable Interventional Accepts healthy volunteers

EXOMIND (BTL-699-2) for the Improvement in Willpower & Food Cravings

NCT07056036
Conditions
Self-Control, Food Cravings
Interventions
ActiveTreatment with BTL-699-2, Sham Treatment with BTL-699-2
Device
Lead sponsor
BTL Industries Ltd.
Industry
Eligibility
22 Years and older
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
4
States / cities
Denver, Colorado • Miami, Florida • Newburgh, Indiana + 1 more
Recruiting Phase 2 Interventional Accepts healthy volunteers

App for Reducing Cravings to Smoke

NCT06088498
Conditions
Smoking
Interventions
Updating Existing Smartphone App, Quitline Services, Quitline Services and Smartphone App
Behavioral
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
3,600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Tampa, Florida
Conditions
Substance Abuse, Substance Dependence
Interventions
Behavioral Intervention
Behavioral
Lead sponsor
Northwell Health
Other
Eligibility
16 Years to 44 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
2
States / cities
Glen Oaks, New York • Manhasset, New York
Conditions
Alcohol Dependence, Alcoholism
Interventions
Naltrexone
Drug
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
21 Years to 50 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Craving, Alcohol Drinking
Interventions
Dynamic Visual Noise (DVN), Static Visual Noise (SVN)
Other
Lead sponsor
University of Wyoming
Other
Eligibility
18 Years to 29 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Laramie, Wyoming
Conditions
Alcoholism
Interventions
acamprosate
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
485 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Alcohol Craving
Interventions
Not listed
Lead sponsor
Boston University
Other
Eligibility
21 Years to 70 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Vagus Nerve Stimulation
Interventions
Active taVNS, Sham taVNS
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 35 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Duluth, Minnesota
Completed Phase 2Phase 3 Interventional

RAE (Realize, Analyze, Engage)

NCT05227339
Conditions
Substance Use Disorders, Treatment Adherence and Compliance
Interventions
RAE
Device
Lead sponsor
ContinueYou, LLC
Industry
Eligibility
18 Years and older
Enrollment
209 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Worcester, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

A Cognitive Behavioral Stress Intervention for Women Who Smoke

NCT03077945
Conditions
Smoking, Cigarette, Smoking Cessation, Stress, Stress, Emotional, Stress Reaction
Interventions
heart rate variability biofeedback and cognitive reappraisal, control tasks
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
New Brunswick, New Jersey
Conditions
Tobacco Dependence, Cigarette Craving, Smoking Behavior
Interventions
Exercise, passive control
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years to 60 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Providence, Rhode Island
Conditions
Smoker, Schizophrenia Diagnosis
Interventions
Not listed
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 55 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Catonsville, Maryland
Completed Early Phase 1 Interventional Accepts healthy volunteers

Cortical rTMS as a Tool to Change Brain Reactivity to Alcohol Cues

NCT02939313
Conditions
Alcohol Dependance
Interventions
medial prefrontal cortex, dorsolateral prefrontal cortex, sham
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years to 40 Years
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Tobacco Use Disorder, Smoking
Interventions
Ariva® Silver Wintergreen, Silver Wintergreen
Other
Lead sponsor
Star Scientific, Inc
Industry
Eligibility
23 Years to 72 Years
Enrollment
111 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Martinsburg, West Virginia
Completed Not applicable Interventional Accepts healthy volunteers

A Mindfulness Mobile Intervention Targeting Reductions in Food Cravings

NCT02694731
Conditions
Food Cravings
Interventions
Mobile application intervention (Device: Smartphone)
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Female only
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
San Francisco, California
Conditions
Cocaine-Related Disorders
Interventions
Pregnenolone (PREG), Placebos
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 60 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
New Haven, Connecticut
Completed Not applicable Interventional Results available

Stress and Marijuana Cue-elicited Craving and Reactivity

NCT00613405
Conditions
Cannabis Use Disorders
Interventions
Stress + cue exposure, No stress + cue exposure
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Schizophrenia and Disorders With Psychotic Features, Tobacco Use Disorder, Schizophrenia
Interventions
Transdermal Nicotine Patch, 21 mg transdermal nicotine, placebo patch
Drug
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 80 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2005
U.S. locations
2
States / cities
Providence, Rhode Island
Terminated Early Phase 1 Interventional Accepts healthy volunteers Results available

Behavioral Effects of Drugs (Inpatient): 38

NCT03954938
Conditions
Cocaine Use, Unspecified
Interventions
Craving Manipulation, Cocaine, Placebo
Behavioral · Drug
Lead sponsor
William Stoops
Other
Eligibility
18 Years to 55 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Lexington, Kentucky
Terminated Phase 1 Interventional Accepts healthy volunteers Results available

The Effects of Exenatide, a GLP-1 Agonist, on Alcohol Self-Administration in Heavy Drinkers

NCT03645408
Conditions
Alcohol Use Disorder
Interventions
Exenatide, Sham injection
Drug · Other
Lead sponsor
Boston Medical Center
Other
Eligibility
21 Years to 55 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Phase 2 Interventional Results available

Use of Donepezil for Treatment of Cocaine Dependence

NCT00467389
Conditions
Cocaine Abuse and Dependence
Interventions
Donepezil, 5 mg daily, Oral Placebo
Drug · Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 50 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Kansas City, Missouri