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Showing 1–24 of 337 matching trials from the live ClinicalTrials.gov search.
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Completed Not applicable Interventional

Standardized Rehabilitation for Intensive Care Unit (ICU) Patients With Acute Respiratory Failure

NCT00976833
View directory record Official record
Conditions
Acute Respiratory Failure
Interventions
Standardized Rehabilitation, Usual Care
Other
Lead sponsor
Wake Forest University
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 9, 2018 · Synced Jul 21, 2026, 10:22 PM EDT
Terminated No phase listed Observational

Determination of the Accuracy of a Non-Invasive Continuous Blood Pressure Device

NCT01311128
View directory record Official record
Conditions
Critically Ill
Interventions
T-line hemodynamic monitoring device (placement and use)
Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 27, 2019 · Synced Jul 21, 2026, 10:22 PM EDT
Completed Phase 3 Interventional

Oral Care to Reduce Mouth and Throat Infections in Critically Ill Patients

NCT00078663
View directory record Official record
Conditions
Critical Illness
Interventions
Oral Care
Behavioral
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years and older
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2011
U.S. locations
5
States / cities
Washington D.C., District of Columbia • Bethesda, Maryland • Fairfax, Virginia + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jul 21, 2026, 10:22 PM EDT
Terminated No phase listed Observational Results available

Variability in Transcranial Doppler Technique in Neuro-Critical Care Patients

NCT04583163
View directory record Official record
Conditions
Cerebral Aneurysm, Stroke, Vasospasm, Cerebral, Subarachnoid Hemorrhage, Aneurysmal, Aneurysmal Subarachnoid Hemorrhage, Cerebral Ischemia
Interventions
Transcranial Doppler
Diagnostic Test
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
18 Years and older
Enrollment
3 participants
Timeline
2020 – 2022
U.S. locations
1
States / cities
Hackensack, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 14, 2025 · Synced Jul 21, 2026, 10:22 PM EDT
Terminated Not applicable Interventional

Assessing Accuracy of the Freestyle Libre Pro Glucose Monitoring in Patients With Diabetes in a Critical Care Setting

NCT06800365
View directory record Official record
Conditions
Diabetes Mellitus, Critical Illness, Continuous Glucose Monitoring
Interventions
Sensor
Device
Lead sponsor
Hennepin Healthcare Research Institute
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 29, 2025 · Synced Jul 21, 2026, 10:22 PM EDT
Completed Not applicable Interventional

Informing Decisions in Chronic Critical Illness: A Randomized Control Trial (RCT)

NCT01230099
View directory record Official record
Conditions
Chronic Critical Illness, Prolonged Mechanical Ventilation
Interventions
Supportive Information Team Group
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
21 Years and older
Enrollment
622 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
4
States / cities
New York, New York • Chapel Hill, North Carolina • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 28, 2015 · Synced Jul 21, 2026, 10:22 PM EDT
Completed Not applicable Interventional

eStimCycle: Early Rehabilitation in Critical Care

NCT02214823
View directory record Official record
Conditions
Intensive Care Unit Acquired Weakness (ICUAW)
Interventions
FES-Cycling, Standard Care
Device · Other
Lead sponsor
Associate Professor Sue Berney PhD, BPT
Other
Eligibility
18 Years and older
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
2
States / cities
Baltimore, Maryland • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 10, 2018 · Synced Jul 21, 2026, 10:22 PM EDT
Terminated Phase 2 Interventional Results available

The Efficacy of Glucagon Like Peptide (GLP) - 1(7-36) Amide for Glycemic Control in Critically Ill Patients

NCT00798590
View directory record Official record
Conditions
Critically Ill, Hypoglycemia
Interventions
Glucagon-Like Peptide-1, Saline
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years to 75 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jul 21, 2026, 10:22 PM EDT
Terminated Not applicable Interventional

Optimal Management of Pain in Hospitalized Patients - Opioid Tolerant Populations.

NCT02470728
View directory record Official record
Conditions
Pain, Acute Pain, Postoperative Pain
Interventions
New Clinical Pathway
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
2
States / cities
Orange, California • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 10, 2025 · Synced Jul 21, 2026, 10:22 PM EDT
Completed Not applicable Interventional Results available

Improving Family Meetings in the Pediatric Cardiac Intensive Care Unit

NCT03749330
View directory record Official record
Conditions
Communication, Critical Illness
Interventions
CICU Team And Loved Ones Communicating (CICU TALC)
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Not listed
Enrollment
451 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 17, 2024 · Synced Jul 21, 2026, 10:22 PM EDT
Completed Not applicable Interventional Results available

A Study Promoting Critical Illness Recovery in the Elderly

NCT02963558
View directory record Official record
Conditions
Acute Respiratory Distress Syndrome, Critical Illness, Critical Care
Interventions
cycle ergometry
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
55 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 17, 2024 · Synced Jul 21, 2026, 10:22 PM EDT
Completed No phase listed Observational

Economic Outcomes of Enteral and Parenteral Proton Pump Inhibitor (PPI) Use in the Intensive Care Unit (ICU)

NCT00919152
View directory record Official record
Conditions
Stress Ulcer Prophylaxis
Interventions
Not listed
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
534 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Oct 5, 2023 · Synced Jul 21, 2026, 10:22 PM EDT
Completed Not applicable Interventional

Wake Forest Post-ICU Telehealth (WFIT) Program

NCT04576065
View directory record Official record
Conditions
Critical Illness
Interventions
WFIT
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
413 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 12, 2023 · Synced Jul 21, 2026, 10:22 PM EDT
Terminated Phase 1Phase 2 Interventional Results available

Project 4A: Inspiratory Muscle Training and Diaphragm Strength

NCT02367170
View directory record Official record
Conditions
Sepsis
Interventions
Bilateral phrenic nerve stimulation and measurement of transdiaphragmatic pressure, Midazolam, Volitional Measurement of Maximal Inspiratory Pressure (MIP), Inspiratory Muscle Strength Training (IMST), SHAM Inspiratory Muscle Strength Training (IMST), Diaphragm thickness measurement, Blood and Urine samples
Procedure · Drug · Device + 1 more
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 6, 2018 · Synced Jul 21, 2026, 10:22 PM EDT
Completed Not applicable Interventional Results available

Daily Checklists and Outcome in the Intensive Care Unit

NCT01396044
View directory record Official record
Conditions
Critical Illness
Interventions
Electronic checklist, Verbal prompting
Other
Lead sponsor
Northwestern University
Other
Eligibility
Not listed
Enrollment
451 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
2
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 3, 2012 · Synced Jul 21, 2026, 10:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Resilience Intervention for Critical Care Nurses

NCT03645512
View directory record Official record
Conditions
Stress
Interventions
Corporate Athlete Resilience (CAR) Training Program
Behavioral
Lead sponsor
AdventHealth
Other
Eligibility
18 Years to 99 Years
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Feb 18, 2020 · Synced Jul 21, 2026, 10:22 PM EDT
Active, not recruiting No phase listed Observational

The BRAIN Intensive Care Unit (ICU) Study: Bringing to Light the Risk Factors

NCT00392795
View directory record Official record
Conditions
Delirium, Cognition Disorders, Dementia
Interventions
Not listed
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
826 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2026
U.S. locations
2
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 1, 2026 · Synced Jul 21, 2026, 10:22 PM EDT
Not yet recruiting No phase listed Observational

TDAP in Burn Patients (Group 2)

NCT07223684
View directory record Official record
Conditions
Sepsis, Burn Injury, Wound Healing, Critical Illness, Multiple Organ Dysfunction Syndrome
Interventions
Observational Cohort (No Intervention)
Other
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years to 80 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
3
States / cities
Tampa, Florida • Atlanta, Georgia • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Jul 21, 2026, 10:22 PM EDT
Not listed Early Phase 1 Interventional

Critical Care Results of SARS-CoV-2 ARDS by Dapsone and Standard COVID-19 Treatment

NCT04918914
View directory record Official record
Conditions
SARS-CoV-2, Hypoxia, ARDS
Interventions
Dapsone 100 MG
Drug
Lead sponsor
Hunt Regional Medical Center
Other
Eligibility
18 Years to 100 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Greenville, Texas
Source: ClinicalTrials.gov public record
Updated Jun 8, 2021 · Synced Jul 21, 2026, 10:22 PM EDT
Completed Phase 2 Interventional Results available

Inulin for Infections in the Intensive Care Unit

NCT03865706
View directory record Official record
Conditions
Antibiotic Resistant Infection, Nosocomial Infection, Pathogen Transmission, Nutrition Disorders, Critical Illness, Sepsis
Interventions
Inulin Oral Suspension, Placebo Oral Suspension, Broad-spectrum antibiotics
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 18, 2025 · Synced Jul 21, 2026, 10:22 PM EDT
Recruiting No phase listed Observational

Prospective Validation of AKI Prediction

NCT06804200
View directory record Official record
Conditions
Acute Kidney Injury
Interventions
Not listed
Lead sponsor
Adam C Dziorny
Other
Eligibility
30 Days to 18 Years
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Jul 21, 2026, 10:22 PM EDT
Completed No phase listed Observational

Pain Assessment in the Intensive Care Unit

NCT01628185
View directory record Official record
Conditions
Delirium, Critical Illness
Interventions
Repositioning
Procedure
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 100 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 16, 2015 · Synced Jul 21, 2026, 10:22 PM EDT
Terminated Not applicable Interventional Results available

Effects of Mobility Devices on Nursing Compliance With Mobility Protocols

NCT01690910
View directory record Official record
Conditions
Mobility Limitations
Interventions
Rifton Gait Trainer, Front Wheeled Walker
Device
Lead sponsor
Trinity Health Michigan
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 12, 2021 · Synced Jul 21, 2026, 10:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Understanding Community Considerations, Opinions, Values, Impacts, and Decisions for COVID-19

NCT04373135
View directory record Official record
Conditions
Covid-19, Critical Illness, Attitude of Health Personnel, Attitude to Health, Health Behavior, Health Care Utilization
Interventions
Brief educational video
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
1,971 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 29, 2025 · Synced Jul 21, 2026, 10:22 PM EDT