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ClinicalTrials.gov public records Last synced May 21, 2026, 11:24 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 331 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Critical Care Clear all
Active, not recruiting Not applicable Interventional
View directory record Official record
Conditions
Respiratory Failure
Interventions
Standing
Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced May 21, 2026, 11:24 PM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Critical Illness, Intensive Care (ICU) Myopathy, PICS, Muscle Weakness
Interventions
Observational study of standard of care
Other
Lead sponsor
University of Kentucky
Other
Eligibility
18 Years and older
Enrollment
66 participants
Timeline
2018 – 2019
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 30, 2020 · Synced May 21, 2026, 11:24 PM EDT
Not listed No phase listed Observational
View directory record Official record
Conditions
Sarcopenia, Muscle Weakness, Critical Illness
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 5, 2018 · Synced May 21, 2026, 11:24 PM EDT
Not listed No phase listed Observational
View directory record Official record
Conditions
Shock
Interventions
CareGuide™ device
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 22, 2017 · Synced May 21, 2026, 11:24 PM EDT
Completed No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Severe Sepsis, Critical Illness
Interventions
Not listed
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2019
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Feb 11, 2020 · Synced May 21, 2026, 11:24 PM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Acute Respiratory Failure, Mechanical Ventilation, Life-Supporting Treatments, Communication, Decision Making, Critical Care, Palliative Care
Interventions
Not listed
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
7,818 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
5
States / cities
Chicago, Illinois • Philadelphia, Pennsylvania • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced May 21, 2026, 11:24 PM EDT
Active, not recruiting No phase listed Observational
View directory record Official record
Conditions
Delirium, Cognition Disorders, Dementia
Interventions
Not listed
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
826 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2026
U.S. locations
2
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 1, 2026 · Synced May 21, 2026, 11:24 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Critical Illness, Intensive Care Unit Syndrome
Interventions
Exercise with Music, Exercise
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 28, 2020 · Synced May 21, 2026, 11:24 PM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Brain Injury, Ischemic Stroke, Hemorrhagic Stroke
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 20, 2016 · Synced May 21, 2026, 11:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Critical Illness
Interventions
Indirect - other patients, Indirect - physiology, Redirection, Direct communication
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
302 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 26, 2020 · Synced May 21, 2026, 11:24 PM EDT
Completed No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Pediatric Intensive Care Unit
Interventions
Not listed
Lead sponsor
Akron Children's Hospital
Other
Eligibility
Up to 15 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Akron, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 25, 2014 · Synced May 21, 2026, 11:24 PM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Respiratory Insufficiency, Depression, Rehabilitation, Critical Care
Interventions
Behavioral Activation - Rehabilitation
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 21, 2025 · Synced May 21, 2026, 11:24 PM EDT
Terminated Phase 2Phase 3 Interventional Results available
View directory record Official record
Conditions
Respiratory Distress Syndrome, Adult
Interventions
Albuterol Sulfate, Mini-Bronchoalveolar Lavage (BAL), Placebo
Drug · Procedure
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
13 Years and older
Enrollment
282 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
40
States / cities
Fresno, California • Sacramento, California • San Francisco, California + 19 more
Source: ClinicalTrials.gov public record
Updated Feb 9, 2017 · Synced May 21, 2026, 11:24 PM EDT
Completed Phase 2 Interventional Results available
View directory record Official record
Conditions
Lung Injury, Acute
Interventions
Dose 1 GSK2586881, Dose 2 GSK2586881, Dose 3 GSK2586881, Dose 4 GSK2586881, Placebo (saline)
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 80 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
13
States / cities
Sacramento, California • Chicago, Illinois • Springfield, Massachusetts + 9 more
Source: ClinicalTrials.gov public record
Updated Sep 27, 2017 · Synced May 21, 2026, 11:24 PM EDT
Completed No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Decision Making
Interventions
medication monitor
Device
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2012
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 9, 2016 · Synced May 21, 2026, 11:24 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Chronic Critical Illness, Prolonged Mechanical Ventilation
Interventions
Supportive Information Team Group
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
21 Years and older
Enrollment
622 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
4
States / cities
New York, New York • Chapel Hill, North Carolina • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 28, 2015 · Synced May 21, 2026, 11:24 PM EDT
Completed Phase 4 Interventional Results available
View directory record Official record
Conditions
Fever, Critical Illness
Interventions
Acetaminophen, Placebo
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 8, 2017 · Synced May 21, 2026, 11:24 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Eye Injuries, Critically Ill
Interventions
plastic wrap over eye & lubrication applied q6 hrs
Procedure
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
2 Weeks to 17 Years
Enrollment
207 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
2
States / cities
Chicago, Illinois • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 9, 2007 · Synced May 21, 2026, 11:24 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Physician-Family Communication in Intensive Care Units, Surrogate Decision-making for Critically Ill Patients
Interventions
Family Support Intervention
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
50 Years and older
Enrollment
159 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 26, 2014 · Synced May 21, 2026, 11:24 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Critical Illness
Interventions
Music Therapy
Other
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
5 Years to 17 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Mar 29, 2020 · Synced May 21, 2026, 11:24 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Patient Handoff, Healthcare Team, Communication, Patient Safety, Intensive Care Units
Interventions
Customized handoff
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
4,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
5
States / cities
Baltimore, Maryland • Camden, New Jersey • Philadelphia, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 7, 2025 · Synced May 21, 2026, 11:24 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Patient Safety, Organizational Change
Interventions
Simulate a functional NICU prior to moving patients
Other
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
Not listed
Enrollment
1,200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Nov 6, 2016 · Synced May 21, 2026, 11:24 PM EDT
Recruiting Phase 3 Interventional
View directory record Official record
Conditions
Delirium, Critical Illness, Sedation Complication, Executive Dysfunction, Post Traumatic Stress Disorder
Interventions
Dexmedetomidine, Midazolam
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
44 Weeks to 11 Years
Enrollment
372 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 28, 2025 · Synced May 21, 2026, 11:24 PM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Critical Care
Interventions
Not listed
Lead sponsor
InLight Solutions
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Jul 21, 2010 · Synced May 21, 2026, 11:24 PM EDT