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ClinicalTrials.gov public records Last synced May 22, 2026, 4:45 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 53 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Critically Ill Intensive Care Unit Patients Clear all
Not listed No phase listed Observational
View directory record Official record
Conditions
Sarcopenia, Muscle Weakness, Critical Illness
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 5, 2018 · Synced May 22, 2026, 4:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Critical Illness
Interventions
Indirect - other patients, Indirect - physiology, Redirection, Direct communication
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
302 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 26, 2020 · Synced May 22, 2026, 4:45 AM EDT
Not listed Not applicable Interventional
View directory record Official record
Conditions
ICU Acquired Weakness
Interventions
Functional electrical stimulation assisted supine cycling (FESC), Conventional early exercise and mobility interventions
Device · Other
Lead sponsor
Community Health System
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Fresno, California
Source: ClinicalTrials.gov public record
Updated Aug 19, 2021 · Synced May 22, 2026, 4:45 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Physician-Family Communication in Intensive Care Units, Surrogate Decision-making for Critically Ill Patients
Interventions
Family Support Intervention
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
50 Years and older
Enrollment
159 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 26, 2014 · Synced May 22, 2026, 4:45 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Surrogate Decision Makers, Prolonged Mechanical Ventilation
Interventions
Decision aid, Usual care
Behavioral · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
416 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
4
States / cities
Chapel Hill, North Carolina • Durham, North Carolina • Pittsburgh, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated May 1, 2019 · Synced May 22, 2026, 4:45 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Critically Ill Intensive Care Unit Patients, Physician-Family Communication in Intensive Care Units, Surrogate Decision-making for Critically Ill Patients
Interventions
Four Supports Intervention, Educational Control Intervention
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
21 Years and older
Enrollment
546 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 13, 2020 · Synced May 22, 2026, 4:45 AM EDT
Terminated Not applicable Interventional
View directory record Official record
Conditions
Mechanical Ventilation, Nonverbal Communication, Intratracheal Intubation, Critical Illness
Interventions
Brain Computer Interface (BCI) device, Communication picture board
Device · Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 16, 2019 · Synced May 22, 2026, 4:45 AM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Critical Illness, Surgery, Aspiration Pneumonia
Interventions
Gastric Ultrasound
Diagnostic Test
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 100 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Jun 26, 2024 · Synced May 22, 2026, 4:45 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Family Members, Post Intensive Care Unit Syndrome, Post Traumatic Stress Disorder
Interventions
Written Summary of Rounds
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 26, 2023 · Synced May 22, 2026, 4:45 AM EDT
Not listed Phase 2 Interventional
View directory record Official record
Conditions
Critically Ill, Hyperglycemia
Interventions
glucose control with computer generated recommendations
Procedure
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
1 Month and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2018
U.S. locations
10
States / cities
Madera, California • Saint Paul, Minnesota • Lebanon, New Hampshire + 5 more
Source: ClinicalTrials.gov public record
Updated Feb 25, 2015 · Synced May 22, 2026, 4:45 AM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Critical Illness, Sleep Deprivation, Circadian Rhythm Sleep Disorder, Unspecified
Interventions
Chronobundle - light, chronobundle - feeding, chronobundle - mobility, chronobundle - sleep
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
2
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced May 22, 2026, 4:45 AM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Intensive Care Unit ICU, Intubation, Critical Illness, Mechanical Ventilation, Pain Measurement, Pain, Procedural, Oxidative Stress, Hypoxia, Biomarkers / Blood, Adult, Uric Acid, Sepsis, COVID, Influenza, Pneumonia
Interventions
endotracheal tube suctioning
Procedure
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated May 20, 2025 · Synced May 22, 2026, 4:45 AM EDT
Terminated Phase 2 Interventional Results available
View directory record Official record
Conditions
Critically Ill, Hypoglycemia
Interventions
Glucagon-Like Peptide-1, Saline
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years to 75 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced May 22, 2026, 4:45 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Diabetes Mellitus
Interventions
Diabetes Diagnosis
Diagnostic Test
Lead sponsor
Stamford Hospital
Other
Eligibility
18 Years and older
Enrollment
1,777 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2022
U.S. locations
1
States / cities
Stamford, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 24, 2022 · Synced May 22, 2026, 4:45 AM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Critical Illness, Pediatrics, General Surgery, Fluid Therapy, Wounds and Injuries
Interventions
Balanced crystalloid solution volume administration, Packed Erythrocytes Units, Blood Product Unit volume, Plasma volume, Platelets volume
Other
Lead sponsor
Columbia University
Other
Eligibility
6 Months to 15 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
4
States / cities
Buffalo, New York • New York, New York • Rochester, New York + 1 more
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced May 22, 2026, 4:45 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
H1N1 Influenza, Seasonal Influenza
Interventions
Not listed
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
12 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 7, 2013 · Synced May 22, 2026, 4:45 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Anxiety, Pain, Critical Illness, Relaxation
Interventions
Therapeutic Music Session
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced May 22, 2026, 4:45 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Critical Illness, Social Isolation, Anxiety, Depression, Post Intensive Care Unit Syndrome
Interventions
Social Engagement
Behavioral
Lead sponsor
Kirby Mayer
Other
Eligibility
18 Years to 99 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jul 13, 2023 · Synced May 22, 2026, 4:45 AM EDT
Completed Phase 3 Interventional
View directory record Official record
Conditions
HIV Infections
Interventions
Lamivudine/Zidovudine, Nelfinavir mesylate, Efavirenz, Lamivudine, Zidovudine
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
9
States / cities
Los Angeles, California • San Diego, California • San Francisco, California + 6 more
Source: ClinicalTrials.gov public record
Updated Mar 1, 2011 · Synced May 22, 2026, 4:45 AM EDT
Completed Phase 1Phase 2 Interventional Results available
View directory record Official record
Conditions
Critical Illness
Interventions
Code Status Video
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 12, 2016 · Synced May 22, 2026, 4:45 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Muscle Weakness, Critical Illness
Interventions
Not listed
Lead sponsor
Naeem Ali, MD
Other
Eligibility
18 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
5
States / cities
Indianapolis, Indiana • Cincinnati, Ohio • Cleveland, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 17, 2016 · Synced May 22, 2026, 4:45 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Sepsis, Respiratory Failure, Renal Failure, Surgical Site Infection
Interventions
Novolin R (human recombinant Insulin)
Drug
Lead sponsor
Genesys
Other
Eligibility
18 Years and older
Enrollment
317 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
Grand Blanc, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 26, 2006 · Synced May 22, 2026, 4:45 AM EDT
Terminated Not applicable Interventional
View directory record Official record
Conditions
Critically-ill
Interventions
Thermal-aided muscle activation
Procedure
Lead sponsor
Niveus Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
5
States / cities
Tucson, Arizona • Baltimore, Maryland • Springfield, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 8, 2013 · Synced May 22, 2026, 4:45 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Intensive Care Unit, Muscle Weakness
Interventions
Neuromuscular Electrostimulation (NMES) CareStim Muscle Stimulation Device (Care Rehab; McLean, VA), Sham
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 22, 2018 · Synced May 22, 2026, 4:45 AM EDT