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Showing 1–24 of 44 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Crush Injuries Clear all
Recruiting Phase 4 Interventional

Evaluating Several Cellular, Acellular, and Matrix-like Products (CAMPs) and Standard of Care Versus Matched Standard of Care Controls in the Management of Nonhealing Pressure Ulcers

NCT06999590
View directory record Official record
Conditions
Pressure Ulcer, Ulcer, Ulcer, Pressure, Pressure Injury
Interventions
ACApatch™, caregraFT™, Standard of Care
Other
Lead sponsor
Tiger Biosciences, LLC.
Industry
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Monroeville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Sep 5, 2026, 4:04 PM EDT
Completed Not applicable Interventional

Evaluation of Wheelchair In-Seat Activity Tracker

NCT04168450
View directory record Official record
Conditions
Pressure Ulcer, Buttock, Pressure Injury, Pressure Ulcer
Interventions
WiSAT System, Passive Feedback, WiSAT System, Active Feedback
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Hines, Illinois • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 9, 2022 · Synced Sep 5, 2026, 4:04 PM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Diagnostic Precision and Accuracy Using the Teed Scoring System Versus the O'Neill Grading System

NCT04726306
View directory record Official record
Conditions
Otic Barotrauma, Pressure Injury, Ear Injury, Barotitis, Barotrauma
Interventions
Otic Barotrauma Grading System
Diagnostic Test
Lead sponsor
Northwell Health
Other
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Sleepy Hollow, New York
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Sep 5, 2026, 4:04 PM EDT
Not yet recruiting No phase listed Observational

Duke Virtual IntEgrated Workflow

NCT07406074
View directory record Official record
Conditions
Falls Injury, Readmission Rates, CLABSI - Central Line Associated Bloodstream Infection, Catheter Associated Urinary Tract Infection, Hospital Acquired Pressure Injury, Venous Thromboembolism (VTE), Nurses, Satisfaction, Patient, Length of Stay
Interventions
Co-Care
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
10,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Sep 5, 2026, 4:04 PM EDT
Completed Not applicable Interventional

Pilot Testing a Patient Safety Display in the Hospital Setting

NCT03950921
View directory record Official record
Conditions
Catheter-Related Infections, Pressure Injury
Interventions
Patient Safety Display
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 31, 2019 · Synced Sep 5, 2026, 4:04 PM EDT
Completed Not applicable Interventional

A Dual-center Study Evaluating Clinical Acceptance of a NPWT Wound Care System

NCT04593693
View directory record Official record
Conditions
Diabetic Foot Ulcer, Pressure Injury, Pressure Ulcer, Surgical Wound, Acute Wound, Traumatic Wound, Dehiscence, Edema
Interventions
Invia Motion Endure NPWT system
Device
Lead sponsor
Medela AG
Industry
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
2
States / cities
Augusta, Georgia • Austell, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 23, 2021 · Synced Sep 5, 2026, 4:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of Sacral Interface Pressure in Healthy Volunteers on Two Dynamic Pressure-Prevention Support Surfaces

NCT06661954
View directory record Official record
Conditions
Healthy Volunteer, Pressure Distribution
Interventions
Bed A - Head of Bed 0 degrees, Bed B - Head of Bed 0 degrees, Bed A - Head of bed at 30 degrees, Bed B - head of bed at 30 degrees
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 89 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 19, 2025 · Synced Sep 5, 2026, 4:04 PM EDT
Active, not recruiting Phase 2 Interventional Accepts healthy volunteers Results available

Skin Change Actions by Nursing

NCT06127524
View directory record Official record
Conditions
Pressure Injury
Interventions
SEM Scanner
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
4,733 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
7
States / cities
Kennett Square, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Sep 5, 2026, 4:04 PM EDT
Completed Not applicable Interventional Results available

Pressure Injury Prevention in the ICU With Multi-Layer Foam Dressings

NCT02962882
View directory record Official record
Conditions
Pressure Incidence Prevention
Interventions
Mepilex Border
Device
Lead sponsor
Molnlycke Health Care AB
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
2
States / cities
Anderson, South Carolina • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 25, 2018 · Synced Sep 5, 2026, 4:04 PM EDT
Completed Not applicable Interventional Results available

Assessment of InfraScanner 2000™ in Detecting Subdural and Epidural Hematomas

NCT03353246
View directory record Official record
Conditions
Head Trauma, Craniocerebral Injuries, Crushing Skull Injury, Head Injuries, Head Injuries, Multiple, Head Injuries, Closed, Head Trauma,Closed, Head Trauma Injury, Head Trauma, Penetrating, Head Injury, Minor, Head Injury Major, Head Injury, Open, Injuries, Craniocerebral, Injuries, Head, Multiple Head Injury, Trauma, Head
Interventions
InfraScanner 2000™
Device
Lead sponsor
Duke University
Other
Eligibility
Not listed
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 19, 2019 · Synced Sep 5, 2026, 4:04 PM EDT
Completed Phase 4 Interventional Results available

Decreasing Intraoperative Skin Damage in Prone Position Surgeries

NCT04884737
View directory record Official record
Conditions
Pressure Injury
Interventions
Mepilex Border Flex® (MBF) dressing
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated May 30, 2023 · Synced Sep 5, 2026, 4:04 PM EDT
Terminated Not applicable Interventional

PuraPly® AM Plus the Standard of Care to Standard of Care Alone for the Management of Stage II-IV Pressure Ulcers.

NCT03502824
View directory record Official record
Conditions
Chronic Pressure Ulcers
Interventions
PuraPly® Antimicrobial Wound Matrix, SOC for Pressure Ulcers
Device · Other
Lead sponsor
Organogenesis
Industry
Eligibility
18 Years to 99 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
2
States / cities
Lake Success, New York • Mineola, New York
Source: ClinicalTrials.gov public record
Updated Sep 21, 2021 · Synced Sep 5, 2026, 4:04 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Comparison of Two Injection Locations in Obese Patients Having Lower Leg/Foot Surgery

NCT01550094
View directory record Official record
Conditions
Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg, Crushing Injury of Lower Leg, Fracture Malunion - Ankle and/ or Foot, Complete Tear, Ankle and/or Foot Ligament, Pathological Fracture - Ankle and/or Foot, Loose Body in Joint of Ankle and/or Foot
Interventions
Not listed
Lead sponsor
Jose Soberon, MD
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Oct 13, 2015 · Synced Sep 5, 2026, 4:04 PM EDT
Completed No phase listed Observational

Efficacy of the Dabir Surfaces Micropressure Overlay for Decubitus Ulcer Prevention During Cardiac Surgery

NCT03884634
View directory record Official record
Conditions
Pressure Ulcer, Pressure Injury
Interventions
Dabir Micropressure Overlay
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
6,627 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 1, 2023 · Synced Sep 5, 2026, 4:04 PM EDT
Completed Not applicable Interventional Results available

RECELL® System Combined With Meshed Autograft for Reduction of Donor Skin Harvesting in Soft Tissue Reconstruction

NCT04091672
View directory record Official record
Conditions
Full-thickness Skin Defects, Degloving Injuries, Crush Injuries, Laceration of Skin, Surgical Wound, Skin Cancer, Cellulitis, Infection, Necrotizing Fasciitis, Gun Shot Wound
Interventions
Control Intervention (Conventional Autograft), Investigational Intervention (RECELL + more widely meshed autograft)
Procedure · Device
Lead sponsor
Avita Medical
Industry
Eligibility
5 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
18
States / cities
Phoenix, Arizona • Tucson, Arizona • Orange, California + 14 more
Source: ClinicalTrials.gov public record
Updated Jul 29, 2024 · Synced Sep 5, 2026, 4:04 PM EDT
Not listed Not applicable Interventional

Effectiveness of the Freedom Bed as Compared to Alternating Pressure Mattress in Treatment of Pressure Injuries in Persons With Limited Mobility Due to Traumatic Brain Injury and /or Spinal Cord Injury

NCT03118960
View directory record Official record
Conditions
Pressure Injury
Interventions
Freedom Bed, Group II Low Air Loss/Alternating Pressure Mattress
Device
Lead sponsor
Northeast Center for Rehabilitation and Brain Injury
Other
Eligibility
14 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Lake Katrine, New York
Source: ClinicalTrials.gov public record
Updated Apr 17, 2017 · Synced Sep 5, 2026, 4:04 PM EDT
Recruiting No phase listed Observational

Myriad™ Augmented Soft Tissue Reconstruction Registry

NCT05243966
View directory record Official record
Conditions
Abdominal Wound Dehiscence, Necrotizing Soft Tissue Infection, Lower Extremity Wound, Pilonidal Sinus, Anal Fistula, Hidradenitis Suppurativa, Pressure Injury
Interventions
Myriad Matrix™ and Myriad Morcells™
Device
Lead sponsor
Aroa Biosurgery Limited
Industry
Eligibility
18 Years and older
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2029
U.S. locations
15
States / cities
Phoenix, Arizona • Los Angeles, California • Fort Myers, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Sep 5, 2026, 4:04 PM EDT
Recruiting Not applicable Interventional

Implementing a Decision Support Tool to Prevent Community-Acquired Pressure Injury in Spinal Cord Injury (SCI) in the Spinal Cord Injury Clinic

NCT06529094
View directory record Official record
Conditions
Spinal Cord Injury, Pressure Injury
Interventions
Provider training, CAPP-FIT intervention with RA facilitation, CAPP-FIT implementation during maintenance phase
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
808 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
7
States / cities
Long Beach, California • Palo Alto, California • Tampa, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Sep 5, 2026, 4:04 PM EDT
Terminated Not applicable Interventional

Nasal Bridge Pressure Injury Prevention

NCT04761679
View directory record Official record
Conditions
Pressure Ulcer of Skin, Pressure Injury
Interventions
Applying the Mepilex foam
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 64 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 18, 2022 · Synced Sep 5, 2026, 4:04 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Gamified Learning for Pressure Injury Prevention

NCT07028892
View directory record Official record
Conditions
Pressure Injuries, Pressure Ulcer Prevention
Interventions
A gamified mobile learning, Booklet training
Device · Other
Lead sponsor
Mehmet Akif Ersoy University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 18, 2025 · Synced Sep 5, 2026, 4:04 PM EDT
Completed Not applicable Interventional Results available

An RCT on Support Surfaces for Pressure Ulcer Prevention

NCT03351049
View directory record Official record
Conditions
Pressure Injury, Pressure Ulcer
Interventions
LAL, Non-LAL
Device
Lead sponsor
David Brienza
Other
Eligibility
18 Years and older
Enrollment
457 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 24, 2023 · Synced Sep 5, 2026, 4:04 PM EDT
Terminated Phase 3 Interventional

Safety and Efficacy of Lidoderm (Lidocaine Patch 5%) in Treating Moderate to Severe Pain Associated With Carpal Tunnel Syndrome

NCT00266214
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
lidocaine patch 5%
Drug
Lead sponsor
Endo USA Inc., a Keenova Therapeutics Company
Industry
Eligibility
18 Years and older
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 13, 2011 · Synced Sep 5, 2026, 4:04 PM EDT
Withdrawn Not applicable Interventional

Use of Hyperbaric Oxygen Therapy for the Treatment of Crush Injuries

NCT04049721
View directory record Official record
Conditions
Crush Injury
Interventions
HBO, Standard of Care
Procedure · Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 99 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 20, 2022 · Synced Sep 5, 2026, 4:04 PM EDT
Completed Not applicable Interventional Results available

Usability Validation of Patient Monitoring Device for Pressure Injury Prevention and Fall Detection

NCT03121144
View directory record Official record
Conditions
Pressure Ulcer, Pressure Injury, Falls Injury
Interventions
Masimo Centroid System
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 31, 2020 · Synced Sep 5, 2026, 4:04 PM EDT