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ClinicalTrials.gov public records Last synced May 21, 2026, 7:38 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 307 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Deep Brain Stimulation Clear all
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Treatment-Refractory Schizophrenia
Interventions
Abbott Laboratories Infinity™ implantable deep brain stimulation system
Device
Lead sponsor
Bradley Lega
Other
Eligibility
22 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 29, 2025 · Synced May 21, 2026, 7:38 PM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Essential Tremor
Interventions
Not listed
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 85 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 8, 2024 · Synced May 21, 2026, 7:38 PM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Chronic Pain
Interventions
Deep Brain Stimulation for Thalamic Pain Syndrome
Device
Lead sponsor
Andre Machado
Other
Eligibility
21 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 8, 2017 · Synced May 21, 2026, 7:38 PM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Parkinson's Disease (PD)
Interventions
Clinician-based DBS programming, Maximum Beta power-based DBS programming, Broad-band electrophysiology-based DBS programming
Device
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 89 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced May 21, 2026, 7:38 PM EDT
Withdrawn Not applicable Interventional
View directory record Official record
Conditions
Essential Tremor
Interventions
Pre-lemniscal Radiation Deep Brain Stimulation
Radiation
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
21 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 20, 2020 · Synced May 21, 2026, 7:38 PM EDT
Recruiting Early Phase 1 Interventional
View directory record Official record
Conditions
Parkinson Disease
Interventions
Deep Brain Stimulation, STN, GP Deep Brain Stimulation
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 89 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2029
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced May 21, 2026, 7:38 PM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Stimulation-ON, Stimulation-OFF, Stimulation-ON Active Control
Device
Lead sponsor
Andrew Krystal
Other
Eligibility
22 Years to 70 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2035
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 30, 2023 · Synced May 21, 2026, 7:38 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Alzheimer Disease
Interventions
DBS-f On, DBS Off
Device
Lead sponsor
Functional Neuromodulation Ltd
Industry
Eligibility
65 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
13
States / cities
Phoenix, Arizona • Los Angeles, California • Stanford, California + 10 more
Source: ClinicalTrials.gov public record
Updated Nov 4, 2024 · Synced May 21, 2026, 7:38 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Deep Brain Stimulation
Procedure
Lead sponsor
University of Florida
Other
Eligibility
23 Years to 65 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2009
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 8, 2011 · Synced May 21, 2026, 7:38 PM EDT
Not yet recruiting Not applicable Interventional
View directory record Official record
Conditions
Parkinson's Disease (PD)
Interventions
Shame Control (Baseline), Standard of Care Deep Brain Stimulation, Illumina 3D Deep Brain Stimulation, Illumina 3D Deep Brain Stimulation Reduced Amplitude, Illumina 3D Deep Brain Stimulation Higher Amplitude
Device
Lead sponsor
Stanford University
Other
Eligibility
21 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Apr 26, 2026 · Synced May 21, 2026, 7:38 PM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Parkinson Disease
Interventions
STN DBS 10Hz, STN DBS 130Hz, STN DBS off
Device
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 14, 2021 · Synced May 21, 2026, 7:38 PM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Obsessive Compulsive Disorder (OCD)
Interventions
Selective focal stimulation of ALIC-pathways
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 11, 2025 · Synced May 21, 2026, 7:38 PM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Parkinson's Disease, Depression, Anxiety
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
40 Years and older
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
2
States / cities
St Louis, Missouri • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated May 3, 2016 · Synced May 21, 2026, 7:38 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Parkinson Disease
Interventions
Deep Brain Stimulation
Device
Lead sponsor
St. Joseph's Hospital and Medical Center, Phoenix
Other
Eligibility
18 Years to 85 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Oct 27, 2022 · Synced May 21, 2026, 7:38 PM EDT
Withdrawn Not applicable Interventional
View directory record Official record
Conditions
Parkinson's Disease
Interventions
GUIDE software, Version 0.1, Clinically defined stimulation parameters
Device
Lead sponsor
Intelect Medical, Inc.
Industry
Eligibility
Not listed
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2010
U.S. locations
4
States / cities
Gainesville, Florida • Manhasset, New York • Kirkland, Washington + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 17, 2011 · Synced May 21, 2026, 7:38 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Summit RC+S System, One Month Blinded Discontinuation Period:
Device · Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
21 Years to 70 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2027
U.S. locations
3
States / cities
Pittsburgh, Pennsylvania • Providence, Rhode Island • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 26, 2026 · Synced May 21, 2026, 7:38 PM EDT
Active, not recruiting Not applicable Interventional
View directory record Official record
Conditions
Parkinson Disease
Interventions
Neural recordings and stimulation
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
40 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 14, 2025 · Synced May 21, 2026, 7:38 PM EDT
Recruiting No phase listed Observational
View directory record Official record
Conditions
Parkinson Disease, Essential Tremor, Dystonia
Interventions
Deep Brain Stimulation
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
Not listed
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
9
States / cities
Phoenix, Arizona • San Francisco, California • Miami, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced May 21, 2026, 7:38 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Deep Brain Stimulation
Device
Lead sponsor
Ali Rezai, MD
Other
Eligibility
20 Years to 60 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 29, 2017 · Synced May 21, 2026, 7:38 PM EDT
Terminated No phase listed Observational
View directory record Official record
Conditions
Essential Tremor, Deep Brain Stimulation, Ataxia, Cerebellar Diseases
Interventions
No intervention
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
2
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 16, 2020 · Synced May 21, 2026, 7:38 PM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Parkinson's Disease, Essential Tremor, Dystonia
Interventions
Medtronic Activa Tremor Control System, Deep Brain Stimulation
Device · Procedure
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 99 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2029
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced May 21, 2026, 7:38 PM EDT
Terminated Not applicable Interventional Results available
View directory record Official record
Conditions
Tourette Syndrome
Interventions
Medtronic Activa Deep Brain Stimulation System
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
15 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced May 21, 2026, 7:38 PM EDT
Recruiting Phase 2Phase 3 Interventional
View directory record Official record
Conditions
Parkinson's Disease (PD), Deep Brain Stimulation
Interventions
buntanetap/posiphen
Drug
Lead sponsor
Annovis Bio Inc.
Industry
Eligibility
40 Years to 85 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
27
States / cities
Birmingham, Alabama • Sun City, Arizona • Fountain Valley, California + 24 more
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced May 21, 2026, 7:38 PM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
Not listed
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 9, 2016 · Synced May 21, 2026, 7:38 PM EDT