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ClinicalTrials.gov public records Last synced Sep 26, 2026, 4:16 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Dermatochalasis Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Dermal Cryotherapy in Patients Undergoing Abdominoplasty

NCT02763306
View directory record Official record
Conditions
Skin Laxity
Interventions
Dermal Cooling System
Device
Lead sponsor
R2 Dermatology
Industry
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
2
States / cities
Folsom, California • Fremont, California
Source: ClinicalTrials.gov public record
Updated Mar 28, 2021 · Synced Sep 26, 2026, 4:16 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Application of the Apsara Thermal Wand System

NCT00662389
View directory record Official record
Conditions
Tightening of Skin Laxity
Interventions
Apsara Thermal Wand System
Device
Lead sponsor
Apsara Medical Corporation
Industry
Eligibility
40 Years to 65 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 27, 2009 · Synced Sep 26, 2026, 4:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The PREFORM Study: Rotational Fractional Resection for Submental Contouring

NCT03966924
View directory record Official record
Conditions
Skin Laxity, Lipodystrophy
Interventions
Rotational fractional resection (1.5mm Diameter Device)
Device
Lead sponsor
Recros Medica, Inc.
Industry
Eligibility
30 Years and older
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Newport Beach, California
Source: ClinicalTrials.gov public record
Updated May 10, 2021 · Synced Sep 26, 2026, 4:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Histological Evaluation of Human Skin Bx to Assess the Effects of APR Tx as an Adjunct Procedure in Facelift Surgery

NCT06243744
View directory record Official record
Conditions
Skin Laxity, Tissue Degeneration, Tissue Breakdown, Collagen Degeneration, Collagen Shrinkage
Interventions
Renuvion APR System
Device
Lead sponsor
Apyx Medical
Industry
Eligibility
18 Years to 75 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
2
States / cities
Bradenton, Florida • Sarasota, Florida
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Sep 26, 2026, 4:16 PM EDT
Completed Not applicable Interventional Results available

Open-label, Prospective Evaluation of the Ulthera® System for Lifting Submental (Under the Chin) and Neck Tissue in Chinese Patients

NCT03351335
View directory record Official record
Conditions
Mild to Moderate Skin Laxity Under the Chin, Mild to Moderate Skin Laxity on Neck
Interventions
Microfocused ultrasound with visualization
Device
Lead sponsor
Merz North America, Inc.
Industry
Eligibility
35 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
7
States / cities
Los Gatos, California • San Diego, California • Vista, California + 4 more
Source: ClinicalTrials.gov public record
Updated Aug 27, 2019 · Synced Sep 26, 2026, 4:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility Study: Evaluation of Ulthera Versus Thermage for Treating the Face and Neck

NCT01713985
View directory record Official record
Conditions
Skin Laxity, Wrinkles
Interventions
Ulthera System Treatment, Thermage
Device
Lead sponsor
Ulthera, Inc
Industry
Eligibility
30 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 23, 2017 · Synced Sep 26, 2026, 4:16 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Combined Treatment Sofwave and Pure Impact to Strength and Tone Muscles and Improve Lax Skin Appearance

NCT06724146
View directory record Official record
Conditions
Skin Lax and Muscle Strength
Interventions
Sofwave and Pure Impact
Device
Lead sponsor
Sofwave Medical LTD
Industry
Eligibility
25 Years to 70 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 8, 2024 · Synced Sep 26, 2026, 4:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

BTL-785F Device for Improving the Structure of Facial Muscles

NCT05524740
View directory record Official record
Conditions
Wrinkle
Interventions
BTL-785-7
Device
Lead sponsor
BTL Industries Ltd.
Industry
Eligibility
21 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 17, 2024 · Synced Sep 26, 2026, 4:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With a Hybrid-Fractional Laser for Facial Rejuvenation

NCT06436261
View directory record Official record
Conditions
Photoaging, Wrinkle, Skin Laxity
Interventions
Hybrid Fractional Laser, Facial Cleanser, Facial Moisturizer, Sunscreen
Procedure · Other
Lead sponsor
Revision Skincare
Industry
Eligibility
35 Years to 65 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
2
States / cities
Atlanta, Georgia • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 30, 2024 · Synced Sep 26, 2026, 4:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Ultherapy® for Treating the Face and Neck Using Standard Versus Simulines Transducers

NCT02416076
View directory record Official record
Conditions
Skin Laxity
Interventions
Ulthera Treatment at EL2, Ulthera Treatment at EL4
Device
Lead sponsor
Ulthera, Inc
Industry
Eligibility
30 Years to 65 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
3
States / cities
Beverly Hills, California • Saratoga, California • Wilmington, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 22, 2019 · Synced Sep 26, 2026, 4:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

CONFORM: Rotational Fractional Resection for Submental Contouring

NCT03407313
View directory record Official record
Conditions
Skin Laxity, Lipodystrophy
Interventions
Rotational fractional resection (1.5mm diameter device)
Device
Lead sponsor
Recros Medica, Inc.
Industry
Eligibility
30 Years and older
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
6
States / cities
Campbell, California • Newport Beach, California • Roseville, California + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 2, 2021 · Synced Sep 26, 2026, 4:16 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Safety and Efficacy of a 2,910 nm Fractional Ablative Fiber Laser (UltraClear®) for Improvements of Skin Laxity and Lifting of the Lower Face, Submental, and Neck Treatment Areas

NCT07759817
View directory record Official record
Conditions
Skin Laxity (Submental and Neck), Skin Lifting and Tightening
Interventions
2910 nm fiber laser (UltraClear®)
Device
Lead sponsor
FA Corporation
Industry
Eligibility
35 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Prospect, Kentucky • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 26, 2026, 4:16 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Safety and Efficacy of Matrix Pro for Eyebrow Lift and Lift of Submental/Neck Laxity

NCT06640998
View directory record Official record
Conditions
Laxity; Skin
Interventions
Matrix Pro
Device
Lead sponsor
Candela Corporation
Industry
Eligibility
18 Years to 75 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Marlborough, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 16, 2024 · Synced Sep 26, 2026, 4:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Treatment for Cellulite Appearance

NCT05358847
View directory record Official record
Conditions
Cellulite
Interventions
Sofwave
Device
Lead sponsor
Sofwave Medical LTD
Industry
Eligibility
18 Years to 60 Years · Female only
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
4
States / cities
Sacramento, California • New York, New York • Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 17, 2023 · Synced Sep 26, 2026, 4:16 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Treatment to Lift Facial Lax Skin and Improve Facial Wrinkles Using Precise and Lift Applicators

NCT06333067
View directory record Official record
Conditions
Lax Skin
Interventions
Sofwave
Device
Lead sponsor
Sofwave Medical LTD
Industry
Eligibility
35 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
2
States / cities
La Mesa, California • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 12, 2025 · Synced Sep 26, 2026, 4:16 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Mechanical Coring to Achieve Directional Skin Tightening

NCT04910945
View directory record Official record
Conditions
Skin Tightening, Healthy Volunteers
Interventions
VENUS AIME (RoboCor)
Device
Lead sponsor
Venus Concept
Industry
Eligibility
30 Years to 70 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
3
States / cities
Los Altos, California • San Jose, California • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 13, 2024 · Synced Sep 26, 2026, 4:16 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Evaluation of SofWave Sofware-Guided Energy Delivery for Lower Face and Neck Rejuvenation

NCT07723664
View directory record Official record
Conditions
Facial Wrinkles, Jawline Contour, Skin Laxity
Interventions
SofWave
Device
Lead sponsor
Sofwave Medical LTD
Industry
Eligibility
40 Years to 55 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 26, 2026 · Synced Sep 26, 2026, 4:16 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Evaluation of Ocular Surface Changes Following RF Electrocoagulation Treatment of the Periorbital Region

NCT03280069
View directory record Official record
Conditions
Skin Laxity, Meibomian Gland Dysfunction
Interventions
THERMIeyes® 20 RF System
Device
Lead sponsor
Ophthalmic Consultants of Long Island
Other
Eligibility
40 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Lynbrook, New York
Source: ClinicalTrials.gov public record
Updated Sep 11, 2017 · Synced Sep 26, 2026, 4:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Comparison of the Effect of Suture Material on Blepharoplasty Incision

NCT04585217
View directory record Official record
Conditions
Dermatochalasis, Ptosis, Eyelid
Interventions
Randomized laterality of suture materials for closure (6-0 polypropylene monofilament suture vs fast absorbing gut suture on right eyelid)
Procedure
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
18 Years to 89 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 22, 2023 · Synced Sep 26, 2026, 4:16 PM EDT
Completed Phase 4 Interventional

Suture Granuloma in Body Contouring Surgery

NCT00223132
View directory record Official record
Conditions
Skin Laxity of Abdomen, Thighs, Chest, Back, and Neck
Interventions
Absorbable sutures
Device
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 24, 2012 · Synced Sep 26, 2026, 4:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility Study: Lifting and Tightening Neck Skin in Patients

NCT01708928
View directory record Official record
Conditions
Skin Laxity
Interventions
Ulthera System Treatment
Device
Lead sponsor
Ulthera, Inc
Industry
Eligibility
30 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 23, 2017 · Synced Sep 26, 2026, 4:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy of Micro-excisional Skin Removal by Micro-coring Device in Treatment of Wrinkles and Laxity of Face and Neck

NCT03583918
View directory record Official record
Conditions
Laxity; Skin
Interventions
HighThroughput Micro Coring Device
Device
Lead sponsor
Cytrellis Biosystems, Inc.
Industry
Eligibility
40 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
5
States / cities
Sacramento, California • Miami, Florida • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 11, 2018 · Synced Sep 26, 2026, 4:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of the Immediate Effect and Safety of DMA™ Novel Muscle Stimulation Technology

NCT04296201
View directory record Official record
Conditions
Skin Laxity, Muscle Contracture
Interventions
DMA treatment
Device
Lead sponsor
Lumenis Be Ltd.
Industry
Eligibility
25 Years to 45 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 16, 2021 · Synced Sep 26, 2026, 4:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Treatment With the Evoke System for Facial and Submental Laxity

NCT04719013
View directory record Official record
Conditions
Laxity; Skin
Interventions
Evoke radiofrequency device
Device
Lead sponsor
InMode MD Ltd.
Industry
Eligibility
35 Years to 75 Years
Enrollment
85 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
5
States / cities
Sacramento, California • Greenwood Village, Colorado • New Orleans, Louisiana + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 30, 2023 · Synced Sep 26, 2026, 4:16 PM EDT