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ClinicalTrials.gov public records Last synced Oct 21, 2026, 1:05 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 85 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Dysphonia Clear all
Terminated Not applicable Interventional Accepts healthy volunteers

Effect of Vocal Exercise After Botulinum Toxin Injection for Spasmodic Dysphonia

NCT00895063
View directory record Official record
Conditions
Spasmodic Dysphonia, Dystonia
Interventions
Vocal Exercise
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 3, 2016 · Synced Oct 21, 2026, 1:05 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

A Study to Analyze Symptoms Prevalent in Early PD (Dysphonia, Tremor)

NCT04288804
View directory record Official record
Conditions
Parkinson Disease
Interventions
Smartphone microphone sensor, Smartphone accelerometer sensor
Device
Lead sponsor
Goalspal LLC
Other
Eligibility
Not listed
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Pleasanton, California
Source: ClinicalTrials.gov public record
Updated Aug 3, 2022 · Synced Oct 21, 2026, 1:05 AM EDT
Completed Not applicable Interventional

Intensive Versus Traditional Voice Therapy

NCT03129880
View directory record Official record
Conditions
Dysphonia
Interventions
Weekly Voice Therapy, Intensive Voice Therapy
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2024
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 16, 2024 · Synced Oct 21, 2026, 1:05 AM EDT
Completed Not applicable Interventional Results available

Assessment of Laryngopharyngeal Sensation in Adductor Spasmodic Dysphonia

NCT05158179
View directory record Official record
Conditions
Spasmodic Dysphonia, Adductor Spasmodic Dysphonia, Voice Disorders
Interventions
Sensation testing
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 85 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 11, 2024 · Synced Oct 21, 2026, 1:05 AM EDT
Recruiting No phase listed Observational

Deep Brain Stimulation for Laryngeal Dystonia: From Mechanism to Optimal Application

NCT05506085
View directory record Official record
Conditions
Laryngeal Dystonia, Adductor Spastic Dysphonia of Dystonia
Interventions
Deep Brain Stimulation
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 70 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2030
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 21, 2026, 1:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

No Post Intubation Laryngeal Symptoms

NCT05383417
View directory record Official record
Conditions
Sore-throat, Dysphonia, Dysphagia, Intubation Complication, Anesthesia Intubation Complication, Anesthesia Morbidity, Anesthesia Complication, Anesthesia; Adverse Effect, Anesthesia; Reaction, Throat Disorder, Throat; Wound, Throat Injury
Interventions
EndoClip
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Sep 10, 2025 · Synced Oct 21, 2026, 1:05 AM EDT
Terminated Not applicable Interventional Results available

Retrospective TIF Study for Treatment of Gastroesophageal Reflux Disease (GERD). The RetroTIF Study

NCT01327963
View directory record Official record
Conditions
Gastroesophageal Reflux Disease (GERD)
Interventions
Transoral Incisionless Fundoplication
Device
Lead sponsor
EndoGastric Solutions
Industry
Eligibility
18 Years to 85 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
2
States / cities
Ocala, Florida • Salem, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 3, 2020 · Synced Oct 21, 2026, 1:05 AM EDT
Recruiting Not applicable Interventional

tDCS for Laryngeal Dystonia

NCT06830174
View directory record Official record
Conditions
Laryngeal Dystonia
Interventions
Starstim system
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Oct 21, 2026, 1:05 AM EDT
Completed Not applicable Interventional Results available

Preliminary Study 2 to Test the Effects of Ambulatory Voice Biofeedback

NCT03416868
View directory record Official record
Conditions
Vocal Fold Nodules, Muscle Tension Dysphonia
Interventions
Ambulatory voice biofeedback
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 17, 2024 · Synced Oct 21, 2026, 1:05 AM EDT
Terminated Phase 4 Interventional Results available

Dietary Control Alone Versus Dietary Control Plus Use of Proton Pump Inhibitors to Treat Pediatric Hoarseness

NCT00637416
View directory record Official record
Conditions
Dysphonia
Interventions
Lansoprazole, Placebo
Drug · Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
3 Years to 18 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jan 23, 2017 · Synced Oct 21, 2026, 1:05 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Characterization of Clinical Phenotypes of Laryngeal Dystonia and Voice Tremor

NCT05150106
View directory record Official record
Conditions
Laryngeal Dystonia, Spasmodic Dysphonia, Tremor
Interventions
Clinical assessments of laryngeal function
Other
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
18 Years to 80 Years
Enrollment
165 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Oct 21, 2026, 1:05 AM EDT
Completed Not applicable Interventional

Assessing the Effects of Patient Self-Rating of Voice Quality on Voice Therapy Attendance and Outcomes

NCT05237648
View directory record Official record
Conditions
Dysphonia
Interventions
Online Voice quality education module, Vocal hygiene module
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 100 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 28, 2025 · Synced Oct 21, 2026, 1:05 AM EDT
Not listed Phase 4 Interventional

Reversal of Botulinum Neurotoxin Injection Related Dysphonia With Pyridostigmine

NCT05110417
View directory record Official record
Conditions
Dysphonia, Spastic, Dysphonia, Laryngeal Dystonia
Interventions
Pyridostigmine Bromide 60 Milligrams (mg)
Drug
Lead sponsor
Eastern Virginia Medical School
Other
Eligibility
21 Years to 100 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 27, 2022 · Synced Oct 21, 2026, 1:05 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Effects of Octanoic Acid for Treatment of Essential Voice Tremor

NCT01864525
View directory record Official record
Conditions
Essential Voice Tremor, Vocal Tremor, Voice Tremor, Essential Tremor of Voice
Interventions
Octanoic acid, Inactive capsule
Drug
Lead sponsor
Syracuse University
Other
Eligibility
21 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Aug 20, 2018 · Synced Oct 21, 2026, 1:05 AM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Understanding Disorder-specific Neural Pathophysiology in Laryngeal Dystonia and Voice Tremor

NCT05216770
View directory record Official record
Conditions
Laryngeal Dystonia, Spasmodic Dysphonia, Tremor
Interventions
Brain imaging, Laryngeal sensory block with topical bupivacaine
Other · Drug
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
18 Years to 80 Years
Enrollment
165 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Oct 21, 2026, 1:05 AM EDT
Completed Phase 2 Interventional Results available

Controlled Study to Evaluate the Safety and Efficacy of Azficel-T for Vocal Fold Scarring and Age-Related Dysphonia

NCT02120781
View directory record Official record
Conditions
Dysphonia Resulting From Vocal Fold Scarring, Age-related Dysphonia
Interventions
Azficel-T (autologous fibroblasts), Placebo
Biological · Drug
Lead sponsor
Castle Creek Biosciences, LLC.
Industry
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
3
States / cities
Los Angeles, California • Stanford, California • New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 3, 2021 · Synced Oct 21, 2026, 1:05 AM EDT
Completed Not applicable Interventional

Effects of Vocal Exercises for Spasmodic Dysphonia

NCT03349086
View directory record Official record
Conditions
Adductor Spasmodic Dysphonia
Interventions
Voice Exercise
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
21 Years to 70 Years · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 23, 2019 · Synced Oct 21, 2026, 1:05 AM EDT
Recruiting Phase 3 Interventional Accepts healthy volunteers

Translaryngeal Vibration for Hyperfunctional Voice Disorders

NCT07145086
View directory record Official record
Conditions
Dysphonia, Muscle Tension Dysphonia
Interventions
Voice therapy with vibration
Behavioral
Lead sponsor
Texas Christian University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Aug 28, 2025 · Synced Oct 21, 2026, 1:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Post-operative Sore Throat as Determined by Endotracheal Tube Inflation Technique

NCT01305265
View directory record Official record
Conditions
Post Operative Sore Throat, Dysphagia, Hoarseness
Interventions
cuff manometer
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
141 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 26, 2014 · Synced Oct 21, 2026, 1:05 AM EDT
Completed No phase listed Observational

The Dystonia Coalition Natural History and Biospecimen Repository for Isolated Dystonias

NCT01373424
View directory record Official record
Conditions
Dystonia
Interventions
Not listed
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
3,265 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2020
U.S. locations
34
States / cities
Birmingham, Alabama • Scottsdale, Arizona • Fountain Valley, California + 26 more
Source: ClinicalTrials.gov public record
Updated Oct 26, 2020 · Synced Oct 21, 2026, 1:05 AM EDT
Not yet recruiting Not applicable Interventional

Assessment of Laryngopharyngeal Sensation: Cancer Survivor Cohort

NCT06078527
View directory record Official record
Conditions
Presbylarynx, Aspiration, Spasmodic Dysphonia, Globus Pharyngeus, Larynx Paralysis, Laryngeal Disease, Vocal Cord Paralysis, Iatrogenic Injury, Sensory Neuropathy
Interventions
Cheung-Bearelly Aesthesiometer, Transnasal Laryngoscopy, Questionnaires
Device · Procedure · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 18, 2026 · Synced Oct 21, 2026, 1:05 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Spasmodic Dysphonia Pain

NCT04648891
View directory record Official record
Conditions
Spasmodic Dysphonia
Interventions
Lidocaine, Vibrating wand
Drug · Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated May 23, 2024 · Synced Oct 21, 2026, 1:05 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Brain-Computer Interfaces in Laryngeal Dystonia

NCT04421365
View directory record Official record
Conditions
Laryngeal Dystonia
Interventions
neurofeedback brain-computer interface (BCI)
Device
Lead sponsor
Kristina Simonyan
Other
Eligibility
18 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Oct 21, 2026, 1:05 AM EDT
Recruiting No phase listed Observational

Imaging Genetics of Laryngeal Dystonia

NCT03042975
View directory record Official record
Conditions
Laryngeal Dystonia, Unaffected Relatives of Laryngeal Dystonia Patients, Voice Tremor, Muscle Tension Dysphonia
Interventions
MRI, Blood draw
Other · Procedure
Lead sponsor
Kristina Simonyan
Other
Eligibility
Not listed
Enrollment
410 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Oct 21, 2026, 1:05 AM EDT