Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.

Clear filters
ClinicalTrials.gov public records Last synced Jul 22, 2026, 12:11 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 53 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Effects of High Altitude Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Mild Hypobaric Hypoxia on Sleep and Post-sleep Performance

NCT00498563
View directory record Official record
Conditions
Altitude, Hypoxia, Environmental Sleep Disorder
Interventions
altitude exposure in hypobaric chamber
Procedure
Lead sponsor
Oklahoma State University Center for Health Sciences
Other
Eligibility
30 Years to 60 Years · Male only
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 23, 2015 · Synced Jul 22, 2026, 12:11 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Effect of Acetazolamide on Subclinical High-Altitude Pulmonary Edema Detected by Lung Ultrasonography

NCT03490916
View directory record Official record
Conditions
High Altitude Pulmonary Edema
Interventions
Acetazolamide, Placebo
Drug
Lead sponsor
Vincent Kan
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 9, 2019 · Synced Jul 22, 2026, 12:11 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Altitude Sickness Prevention and Efficacy of Comparative Treatments

NCT02604173
View directory record Official record
Conditions
Acute Mountain Sickness
Interventions
Budesonide, Acetazolamide, Placebo
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 65 Years
Enrollment
103 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Bishop, California
Source: ClinicalTrials.gov public record
Updated Dec 11, 2018 · Synced Jul 22, 2026, 12:11 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Sickness Evaluation at Altitude With Acetazolamide at Relative Doses

NCT03828474
View directory record Official record
Conditions
Acute Mountain Sickness
Interventions
Acetazolamide Pill
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 75 Years
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Bishop, California
Source: ClinicalTrials.gov public record
Updated Oct 21, 2019 · Synced Jul 22, 2026, 12:11 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Effects of High Altitude on AMPK Activation

NCT02391519
View directory record Official record
Conditions
Pregnancy, IUGR, Preeclampsia
Interventions
Collection of myometrial, cord blood, and placental tissue samples
Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Jul 22, 2026, 12:11 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Three New Ideas to Protect Special Forces From the Stress of High Altitude

NCT02463357
View directory record Official record
Conditions
Mountain Sickness
Interventions
Quercetin, Nifedipine extended release, Methazolamide, Metformin, Placebo, Nitrite
Dietary Supplement · Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 30 Years · Male only
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Alma, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 29, 2021 · Synced Jul 22, 2026, 12:11 AM EDT
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

Pharmacological Countermeasures for High Altitude

NCT05300477
View directory record Official record
Conditions
Hypobaric Hypoxia
Interventions
Acetazolamide, Erythropoietin
Drug
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 40 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 25, 2025 · Synced Jul 22, 2026, 12:11 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

The Safety Evaluation of Aminophylline and Ambrisentan When Administered Orally Alone and in Combination to Healthy Volunteers

NCT01530464
View directory record Official record
Conditions
High Altitude Pulmonary Hypertension
Interventions
Aminophylline, Ambrisentan, Aminophylline plus ambrisentan
Drug
Lead sponsor
Thies Schroeder
Other
Eligibility
18 Years to 40 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 15, 2014 · Synced Jul 22, 2026, 12:11 AM EDT
Recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers

Advair HFA in Healthy and HAPE Predisposed Subjects

NCT06040268
View directory record Official record
Conditions
Altitude Edema
Interventions
Advair HFA, Placebo
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 50 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 21, 2025 · Synced Jul 22, 2026, 12:11 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Oxygen Transport in Normobaric vs. Hypobaric Hypoxia

NCT03335917
View directory record Official record
Conditions
Hypoxia, Altitude, Exercise
Interventions
Hypoxia, Exercise
Other
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years to 45 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 28, 2023 · Synced Jul 22, 2026, 12:11 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating the Utility of Continuous Positive Airway Pressure in the Treatment of High Altitude Pulmonary Edema

NCT04186598
View directory record Official record
Conditions
Continuous Positive Airway Pressure, High Altitude Pulmonary Edema
Interventions
CPAP mask system, Nifedipine 30 MG, CPAP mask system without PEEP
Device · Drug
Lead sponsor
CommonSpirit Health
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Breckenridge, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 6, 2024 · Synced Jul 22, 2026, 12:11 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

High Altitude and Exogenous Carbohydrate Oxidation

NCT03851744
View directory record Official record
Conditions
Glucose Metabolism, High Altitude
Interventions
Sea Level, High Altitude
Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 39 Years · Male only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 1, 2021 · Synced Jul 22, 2026, 12:11 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Ketone Monoester Supplements, High Altitude, and Brain Blood Flow During Exercise

NCT07063732
View directory record Official record
Conditions
High Altitude Hypoxia, Exercise
Interventions
Ketone Monoester (KME), Placebo
Dietary Supplement
Lead sponsor
McMaster University
Other
Eligibility
18 Years to 35 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Bishop, California
Source: ClinicalTrials.gov public record
Updated Jul 13, 2025 · Synced Jul 22, 2026, 12:11 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

WatchPAT Compared to PSG at 8500'

NCT04249011
View directory record Official record
Conditions
Sleep Disorder; Breathing-Related
Interventions
Not listed
Lead sponsor
Itamar-Medical, Israel
Industry
Eligibility
17 Years and older
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Woodland Park, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 29, 2020 · Synced Jul 22, 2026, 12:11 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Prochlorperazine Maleate Versus Placebo for the Prophylaxis of Acute Mountain Sickness

NCT06450899
View directory record Official record
Conditions
Acute Mountain Sickness
Interventions
Prochlorperazine Maleate, Placebo
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 75 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Evergreen, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Jul 22, 2026, 12:11 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Decompression Tables for Diving at Altitude

NCT03390335
View directory record Official record
Conditions
Decompression Sickness, Acute Mountain Sickness
Interventions
Pressure, Breathing Gas
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years to 40 Years
Enrollment
103 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 13, 2021 · Synced Jul 22, 2026, 12:11 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Pharmacologic Induction of Tolerance for Hypoxia & Hypothermia

NCT06129825
View directory record Official record
Conditions
Hypothermia, Hypoxia, Mountain Sickness
Interventions
Prospective
Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 88 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Jul 22, 2026, 12:11 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Substrate Utilization, Exercise Performance, and Skeletal Muscle Response to Energy Deficit and Altitude Acclimatization

NCT02731066
View directory record Official record
Conditions
Weight Loss, Other Effects of High Altitude
Interventions
Standard pro, High pro, carbo bev, placebo bev
Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 42 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 5, 2017 · Synced Jul 22, 2026, 12:11 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effects of Continuous Positive Airway Pressure on Peripheral Oxygen Saturation, Work of Breathing, and Exercise Tolerance at Altitude

NCT05971290
View directory record Official record
Conditions
Hypoxemia, Altitude Hypoxia
Interventions
Continuous positive airway pressure, Ambient air
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 1, 2023 · Synced Jul 22, 2026, 12:11 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Prevention of Altitude Illness With Non-steroidal Anti-inflammatory Study (PAINS)

NCT01171794
View directory record Official record
Conditions
Altitude Sickness
Interventions
Ibuprofen, Placebo
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 65 Years
Enrollment
89 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Dec 12, 2018 · Synced Jul 22, 2026, 12:11 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Breathing Training to Improve Human Performance at High Altitude

NCT03530163
View directory record Official record
Conditions
Mountain Sickness Acute
Interventions
Respiratory Muscle Training, Sham Breathing Training
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 45 Years · Male only
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 18, 2022 · Synced Jul 22, 2026, 12:11 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Effects of Non-steroidal Anti-inflammatory Drugs (NSAIDS) on Acclimatization to High Altitude

NCT02233582
View directory record Official record
Conditions
High Altitude
Interventions
Ibuprofen, Sugar pill
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
2
States / cities
Bishop, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 5, 2021 · Synced Jul 22, 2026, 12:11 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Efficacy of Prophylactic Treatment of Oral Prochlorperazine for Acute Mountain Sickness

NCT06310642
View directory record Official record
Conditions
AMS, Acute Mountain Sickness
Interventions
Immediate descent from altitude., Diphenhydramine, Prochlorperazine 10 mg
Other · Drug
Lead sponsor
CHRISTUS Health
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Corpus Christi, Texas
Source: ClinicalTrials.gov public record
Updated May 27, 2024 · Synced Jul 22, 2026, 12:11 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Colorado-Oregon Altitude Study

NCT05734716
View directory record Official record
Conditions
Acute Mountain Sickness
Interventions
Erythropoietin, Iron sucrose (Venofer), Sterile Sodium Chloride
Drug
Lead sponsor
University of Oregon
Other
Eligibility
18 Years to 40 Years
Enrollment
121 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
2
States / cities
Leadville, Colorado • Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 9, 2023 · Synced Jul 22, 2026, 12:11 AM EDT