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Showing 1–24 of 190 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Erectile Dysfunction Clear all
Recruiting Phase 1Phase 2 Interventional

Stem Cells for Erectile Dysfunction Post RALP

NCT07048314
View directory record Official record
Conditions
Erectile Dysfunction, Prostate Cancer
Interventions
Allogeneic adipose-derived mesenchymal stem cells (HB-adMSCs) at the doctor's office, Allogeneic adipose-derived mesenchymal stem cells (HB-adMSCs) in the OR, Placebo in the OR, Placebo in clinic
Drug
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
40 Years to 70 Years · Male only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Jul 21, 2026, 6:56 AM EDT
Completed Phase 3 Interventional Results available

Tadalafil Taken Daily Compared to Placebo on Improvement of Getting and Maintaining an Erection and Sexual Quality of Life

NCT00422734
View directory record Official record
Conditions
Impotence
Interventions
tadalafil, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older · Male only
Enrollment
342 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
10
States / cities
Huntsville, Alabama • Little Rock, Arkansas • Newport Beach, California + 7 more
Source: ClinicalTrials.gov public record
Updated Jun 9, 2009 · Synced Jul 21, 2026, 6:56 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Assess the Effect of Daily Treatment of Vardenafil 20mg or Sildenafil 100mg and Placebo on Sperm Function

NCT00655590
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
Levitra (Vardenafil, BAY38-9456), Sildenafil, Placebo
Drug
Lead sponsor
Bayer
Industry
Eligibility
25 Years to 64 Years · Male only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2006
U.S. locations
18
States / cities
Phoenix, Arizona • Tempe, Arizona • Beverly Hills, California + 15 more
Source: ClinicalTrials.gov public record
Updated Dec 29, 2014 · Synced Jul 21, 2026, 6:56 AM EDT
Completed Phase 3 Interventional

Study to Compare the Tolerability and Efficacy of Once Daily Vardenafil vs Vardenafil PRN vs Placebo in Men Immediately After Nerve-sparing Prostatectomy for Improving ED

NCT00492635
View directory record Official record
Conditions
Erectile Dysfunction, Sexual Dysfunction, Physiological
Interventions
Levitra (Vardenafil, BAY38-9456), Placebo
Drug
Lead sponsor
Bayer
Industry
Eligibility
18 Years to 64 Years · Male only
Enrollment
628 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
11
States / cities
Laguna Hills, California • Jeffersonville, Indiana • Des Moines, Iowa + 8 more
Source: ClinicalTrials.gov public record
Updated Oct 27, 2014 · Synced Jul 21, 2026, 6:56 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Study Evaluating the Effects of Avanafil on Semen Parameters

NCT01768676
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
avanafil, Placebo
Drug
Lead sponsor
VIVUS LLC
Industry
Eligibility
18 Years to 45 Years · Male only
Enrollment
181 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
15
States / cities
Huntsville, Alabama • Los Angeles, California • San Diego, California + 12 more
Source: ClinicalTrials.gov public record
Updated Dec 13, 2015 · Synced Jul 21, 2026, 6:56 AM EDT
Completed Phase 1 Interventional

ARIES for Vasculogenic Erectile Dysfunction

NCT02620982
View directory record Official record
Conditions
Erectile Dysfunction, Sexual Dysfunction, Physiological
Interventions
ARIES (Extracorporal Shock Wave Application)
Device
Lead sponsor
Dornier MedTech Systems
Industry
Eligibility
21 Years to 75 Years · Male only
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 28, 2016 · Synced Jul 21, 2026, 6:56 AM EDT
Not listed Not applicable Interventional

Evaluate the Use of Liposuction and Cell Separation Devices for Autologous Fat (Adipose) Derived Cells to Treat the Symptoms of Erectile Dysfunction

NCT01601353
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
Tissue Genesis Cell Isolation System
Device
Lead sponsor
Tissue Genesis
Industry
Eligibility
40 Years to 70 Years · Male only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2021
U.S. locations
2
States / cities
San Diego, California • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 23, 2021 · Synced Jul 21, 2026, 6:56 AM EDT
Terminated Not applicable Interventional

Dornier Aries 2 Extracorporeal Shock Wave Device for the Treatment of Mild Erectile Dysfunction (ED)

NCT03039218
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
Dornier Aries 2, Placebo / Sham
Device
Lead sponsor
Dornier MedTech Systems
Industry
Eligibility
22 Years to 70 Years · Male only
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
4
States / cities
San Diego, California • Omaha, Nebraska • Brooklyn, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 16, 2018 · Synced Jul 21, 2026, 6:56 AM EDT
Not listed Phase 4 Interventional

Can Hyperbaric Oxygen Improve Erectile Function Following Surgery for Prostate Cancer

NCT00906269
View directory record Official record
Conditions
Impotence, Prostatic Neoplasms
Interventions
Sildenafil therapy plus post-NSRRP HBO2T, Sildenafil therapy plus sham post-NSRRP HBO2T
Drug
Lead sponsor
Hartford Hospital
Other
Eligibility
40 Years to 65 Years · Male only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2021
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated May 19, 2019 · Synced Jul 21, 2026, 6:56 AM EDT
Recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers

Mesenchymal Stem Cells for the Treatment of Various Chronic and Acute Conditions

NCT04684602
View directory record Official record
Conditions
Autoimmune Diseases, Cardiovascular Disorders, Diabetes Complications, Integumentary Disease, Musculoskeletal Disorders, Neurodegenerative Disorders, Neurologic Disorders, Pulmonary Disorders, Sexual Dysfunction, Urologic Disorders, Viral Illness
Interventions
PrimePro™/ PrimeMSK™
Biological
Lead sponsor
Thomas Advanced Medical LLC
Industry
Eligibility
18 Years and older
Enrollment
5,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2030
U.S. locations
1
States / cities
Culver City, California
Source: ClinicalTrials.gov public record
Updated Apr 28, 2022 · Synced Jul 21, 2026, 6:56 AM EDT
Recruiting Not applicable Interventional

Penile Lengthening Pre-Penile Prosthesis Implantation

NCT07053826
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
Penile Traction Device, Inflatable Penile Prosthesis Implantation
Device · Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Male only
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 4, 2025 · Synced Jul 21, 2026, 6:56 AM EDT
Completed Phase 2 Interventional

Assessment of Onset, Safety & Toleration of UK-369,003 in Male Erectile Dysfunction

NCT00141349
View directory record Official record
Conditions
Impotence
Interventions
UK-369,003
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 65 Years · Male only
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005
U.S. locations
39
States / cities
Birmingham, Alabama • Mesa, Arizona • Tempe, Arizona + 30 more
Source: ClinicalTrials.gov public record
Updated Jul 24, 2006 · Synced Jul 21, 2026, 6:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Uroxatral in Men With Benign Prostate Hypertrophy (BPH) and Erectile Dysfunction (ED)

NCT00256399
View directory record Official record
Conditions
BPH, Erectile Dysfunction
Interventions
Alfuzosin 10 mg
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
45 Years to 75 Years · Male only
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 14, 2022 · Synced Jul 21, 2026, 6:56 AM EDT
Completed Phase 2 Interventional

POMx In the Treatment of Erectile Dysfunction

NCT01220206
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
Placebo, One POMx capsule daily, 2 POMx Capsules
Drug
Lead sponsor
POM Wonderful LLC
Industry
Eligibility
21 Years to 70 Years · Male only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Huntsville, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 4, 2012 · Synced Jul 21, 2026, 6:56 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Impact of Dietary Pattern on Erectile Function

NCT04349059
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
Animal based diet, Plant based diet
Other
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Nov 11, 2025 · Synced Jul 21, 2026, 6:56 AM EDT
Not yet recruiting Not applicable Interventional

Rehabilitation and Sex Therapy to Optimize Recovery After Prostate Cancer Treatment

NCT07685249
View directory record Official record
Conditions
Prostate Cancer, Urinary Incontinence, Erectile Dysfunction
Interventions
Sex Therapy, Pelvic Floor Physical Therapy, Vacuum Erection Device (VED)
Behavioral · Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Male only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Jul 21, 2026, 6:56 AM EDT
Completed Not applicable Interventional Results available

Low Intensity Shock Wave Therapy in the Management of Erectile Dysfunction

NCT04136288
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
MoreNova
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
40 Years to 55 Years · Male only
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 11, 2024 · Synced Jul 21, 2026, 6:56 AM EDT
Completed Not applicable Interventional Results available

MED3000 Topical Gel for On-Demand Treatment of Post-Radical Prostatectomy Erectile Dysfunction

NCT05673005
View directory record Official record
Conditions
Erectile Dysfunction Following Radical Prostatectomy
Interventions
MED3000 topical gel
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
40 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Jul 21, 2026, 6:56 AM EDT
Terminated Phase 2 Interventional

Hypoactive Sexual Desire Disorder in Males

NCT04002661
View directory record Official record
Conditions
Low Libido
Interventions
Flibanserin, Placebo
Drug
Lead sponsor
Mohit Khera
Other
Eligibility
18 Years to 69 Years · Male only
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 25, 2026 · Synced Jul 21, 2026, 6:56 AM EDT
Withdrawn Not applicable Interventional

Focused Shock Wave Therapy Outcomes in Peyronie's Disease and Erectile Dysfunction

NCT05646602
View directory record Official record
Conditions
Peyronie Disease, Penile Curvature, Erectile Dysfunction
Interventions
Collagenase Clostridium Histolyticum, Duolith SD1 T-TOP
Drug · Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 9, 2023 · Synced Jul 21, 2026, 6:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Use of an External Erectile Device in Transgender Man Following Phalloplasty

NCT03823014
View directory record Official record
Conditions
Transsexualism, Surgery, Sex Behavior, Erectile Dysfunction
Interventions
Elator
Device
Lead sponsor
Boston Children's Hospital
Other
Eligibility
18 Years to 64 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 20, 2022 · Synced Jul 21, 2026, 6:56 AM EDT
Recruiting No phase listed Observational

Genetic Study of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)

NCT00499317
View directory record Official record
Conditions
Chronic Prostatitis (CP), Chronic Pelvic Pain Syndrome (CPPS), Painful Bladder Syndrome (PBS), Benign Frequency Syndrome (BFS), Interstitial Cystitis
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Not listed
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Jul 21, 2026, 6:56 AM EDT
Completed Phase 2 Interventional

Phase 2a Topical Sildenafil Proof-of-Concept Study in Men With Mild to Moderate ED

NCT02390960
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
Sildenafil Cream, Placebo Cream, Penile Plethysmography (RigiScan)
Drug · Device
Lead sponsor
Strategic Science & Technologies, LLC
Industry
Eligibility
18 Years to 70 Years · Male only
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
3
States / cities
San Diego, California • New Orleans, Louisiana • New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 11, 2017 · Synced Jul 21, 2026, 6:56 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Incidence and Treatment of Insulin Resistance Among Men With Erectile Dysfunction

NCT00284960
View directory record Official record
Conditions
Erectile Dysfunction, Metabolic Syndrome, Insulin Resistance
Interventions
Not listed
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 2, 2017 · Synced Jul 21, 2026, 6:56 AM EDT