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ClinicalTrials.gov public records Last synced May 22, 2026, 12:11 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–17 of 17 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Esophageal Hernia Clear all
Completed No phase listed Observational
View directory record Official record
Conditions
Gastro Esophageal Reflux
Interventions
Esophyx
Device
Lead sponsor
Peter G Mavrelis
Individual
Eligibility
18 Years to 80 Years
Enrollment
99 participants
Timeline
2014 – 2016
U.S. locations
2
States / cities
Merrillville, Indiana • Appleton, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 7, 2017 · Synced May 22, 2026, 12:11 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Esophageal Hernia, Hernia, Esophageal, Hernia, Paraesophageal, Hiatal Hernia, Paraesophageal Hiatal Hernia, Sliding Esophageal Hernia, Sliding Hiatal Hernia
Interventions
Not listed
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 5, 2023 · Synced May 22, 2026, 12:11 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available
View directory record Official record
Conditions
Morbid Obesity, Hernia, Colorectal Cancer, Laparoscopy
Interventions
Not listed
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Dec 5, 2021 · Synced May 22, 2026, 12:11 AM EDT
Not listed No phase listed Observational
View directory record Official record
Conditions
Gastroesophageal Reflux Disease, Hiatal Hernia
Interventions
Laparoscopic Fundoplication, LINX Antireflux
Procedure · Device
Lead sponsor
The Heartburn Foundation
Other
Eligibility
21 Years and older
Enrollment
2,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2025
U.S. locations
19
States / cities
Birmingham, Alabama • Mobile, Alabama • Heber Springs, Arkansas + 15 more
Source: ClinicalTrials.gov public record
Updated Feb 20, 2023 · Synced May 22, 2026, 12:11 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Gastroesophageal Reflux Disease, Hiatal Hernia
Interventions
TIF Procedure
Procedure
Lead sponsor
EndoGastric Solutions
Industry
Eligibility
18 Years to 75 Years
Enrollment
278 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2018
U.S. locations
14
States / cities
Safford, Arizona • Tempe, Arizona • Englewood, Colorado + 11 more
Source: ClinicalTrials.gov public record
Updated Mar 5, 2019 · Synced May 22, 2026, 12:11 AM EDT
Active, not recruiting Not applicable Interventional
View directory record Official record
Conditions
Hiatal Hernia Large, Reflux, Gastroesophageal
Interventions
Hiatal Hernia Repair with Platelet Rich Plasma, Hiatal Hernia Repair without Platelet Rich Plasma
Procedure
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
2
States / cities
Los Angeles, California • Newport Beach, California
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced May 22, 2026, 12:11 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Gastroesophageal Reflux Disease, Hiatal Hernia, Paraesophageal Hernia
Interventions
Not listed
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 4, 2023 · Synced May 22, 2026, 12:11 AM EDT
Terminated No phase listed Observational
View directory record Official record
Conditions
Hiatal Hernia Large, Gastro Esophageal Reflux, Hiatal Hernia, Hiatal Hernia, Paraesophageal, Reflux, Gastroesophageal, Reflux Acid
Interventions
LINX Reflux Management System, Fundoplication
Device · Procedure
Lead sponsor
Foregut Research Foundation
Other
Eligibility
21 Years and older
Enrollment
336 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
6
States / cities
Los Angeles, California • Lone Tree, Colorado • Coral Springs, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 8, 2026 · Synced May 22, 2026, 12:11 AM EDT
Completed No phase listed Observational Results available
View directory record Official record
Conditions
Hiatal Hernia With Gastroesophageal Reflux Disease, Gastroesophageal Reflux, GERD
Interventions
Hepatic derived surgical matrix
Biological
Lead sponsor
Miromatrix Medical Inc.
Industry
Eligibility
Not listed
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Lorton, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 30, 2019 · Synced May 22, 2026, 12:11 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Gastroesophageal Reflux Disease, Hiatal Hernia
Interventions
TIF Transoral Fundoplication, Sham placebo procedure
Device · Other
Lead sponsor
EndoGastric Solutions
Industry
Eligibility
18 Years to 80 Years
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
9
States / cities
Los Angeles, California • Englewood, Colorado • Chicago, Illinois + 5 more
Source: ClinicalTrials.gov public record
Updated Dec 2, 2021 · Synced May 22, 2026, 12:11 AM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Paraesophageal Hernia, GERD
Interventions
OviTex Mesh, Pledgeted sutures
Device · Other
Lead sponsor
David Krpata
Other
Eligibility
18 Years and older
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 6, 2025 · Synced May 22, 2026, 12:11 AM EDT
Active, not recruiting Not applicable Interventional
View directory record Official record
Conditions
GERD, Hiatal Hernia
Interventions
LAPAROSCOPIC PARAESOPHAGEAL HIATAL HERNIA REPAIR COMBINED WITH TRANSORAL INCISIONLESS FUNDOPLICATION
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
22 Years to 80 Years
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2030
U.S. locations
7
States / cities
Irvine, California • Los Angeles, California • Englewood, Colorado + 4 more
Source: ClinicalTrials.gov public record
Updated Aug 18, 2025 · Synced May 22, 2026, 12:11 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Gastroesophageal Reflux Disease, Hiatal Hernia
Interventions
Lap. Fundo. with Mobilization of the Esophageal Junction, Lap. Fundo. without Mobilization of the Esophageal Junction
Procedure
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
Up to 18 Years
Enrollment
177 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
2
States / cities
Birmingham, Alabama • Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 21, 2009 · Synced May 22, 2026, 12:11 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Paraesophageal Hernia
Interventions
Laparoscopic paraesophageal hernia repair without fundoplication
Procedure
Lead sponsor
The Foundation for Surgical Innovation and Education
Other
Eligibility
18 Years and older
Enrollment
260 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2029
U.S. locations
2
States / cities
Evanston, Illinois • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 26, 2024 · Synced May 22, 2026, 12:11 AM EDT
Terminated No phase listed Observational
View directory record Official record
Conditions
Gastroesophageal Reflux, Fundoplication, Hernia, Hiatal, Surveys and Questionnaires
Interventions
Mayo Clinic Foregut Surgery Report Card Questionnaire
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
274 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 21, 2024 · Synced May 22, 2026, 12:11 AM EDT
Recruiting No phase listed Observational
View directory record Official record
Conditions
Esophageal Cancer, Gastroesophageal Reflux Disease (GERD), Esophageal Diseases, Hiatal Hernia, Esophageal Achalasia
Interventions
Survey of client health, personal habits, family history, Blood specimen for non-DNA and DNA parts, Biopsy of esophageal/stomach tissue, lymph nodes, tumor, Biopsies, oral (saliva) and/or secretions, washings or mucosal scrapings/brushing from routine clinical surveillance endoscopies
Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
7,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2050
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced May 22, 2026, 12:11 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Congenital Diaphragmatic Hernia, Tracheoesophageal Fistula, Esophageal Atresia
Interventions
Thoracoscopic surgery
Procedure
Lead sponsor
Arlyne Thung
Other
Eligibility
Up to 6 Months
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 11, 2018 · Synced May 22, 2026, 12:11 AM EDT