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ClinicalTrials.gov public records Last synced May 22, 2026, 2:44 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Extubation Clear all
Not listed No phase listed Observational
View directory record Official record
Conditions
Muscle Weakness, Renal Failure, Respiratory Comorbidities
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 21, 2013 · Synced May 22, 2026, 2:44 AM EDT
Completed Phase 4 Interventional Results available
View directory record Official record
Conditions
Incomplete Reversal of Neuromuscular Block
Interventions
Sugammadex, Neostigmine
Drug
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years to 99 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated May 21, 2020 · Synced May 22, 2026, 2:44 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Respiratory Distress Syndrome
Interventions
Not listed
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
1 Hour to 28 Days
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Mar 10, 2016 · Synced May 22, 2026, 2:44 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Thoracic Diseases
Interventions
Fiberoptic Endoscopic Evaluation of Swallowing
Procedure
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 90 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
3
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 23, 2021 · Synced May 22, 2026, 2:44 AM EDT
Completed Phase 4 Interventional Results available
View directory record Official record
Conditions
Coronary Artery Bypass Graft and/or Aortic Valve Replacement Surgery
Interventions
Sugammadex, Placebo
Drug · Other
Lead sponsor
Yale University
Other
Eligibility
21 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 13, 2022 · Synced May 22, 2026, 2:44 AM EDT
Recruiting Phase 2 Interventional
View directory record Official record
Conditions
Dysphagia, Laryngeal Edema
Interventions
Methylprednisolone, Normal Saline
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced May 22, 2026, 2:44 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Mechanical Ventilation Complication, Acute Respiratory Failure, Intubation Complication
Interventions
Protocolized post-extubation respiratory support, Usual Care
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
751 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 28, 2023 · Synced May 22, 2026, 2:44 AM EDT
Completed Phase 2 Interventional Results available
View directory record Official record
Conditions
Tetralogy of Fallot (TOF), Ventricular Septal Defects (VSD), Atrioventricular Septal Defects (AVSD)
Interventions
Fentanyl (High Dose), Fentanyl (Low Dose), Fentanyl (Low Dose) + Dexmedetomidine
Drug
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
1 Month to 3 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 26, 2018 · Synced May 22, 2026, 2:44 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Respiratory Insufficiency
Interventions
Music Therapy
Behavioral
Lead sponsor
Northwell Health
Other
Eligibility
Up to 18 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
New Hyde Park, New York
Source: ClinicalTrials.gov public record
Updated Sep 12, 2023 · Synced May 22, 2026, 2:44 AM EDT
Not yet recruiting Not applicable Interventional
View directory record Official record
Conditions
Motility Function
Interventions
High resolution solid state manometry
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 70 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 9, 2022 · Synced May 22, 2026, 2:44 AM EDT
Not listed No phase listed Observational
View directory record Official record
Conditions
Extubation
Interventions
NAVA (Extubation readiness testing failures)
Device
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Up to 18 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 3, 2009 · Synced May 22, 2026, 2:44 AM EDT
Completed Phase 4 Interventional Results available
View directory record Official record
Conditions
Neuromuscular Blockade, Chronic Obstructive Pulmonary Disease
Interventions
neostigmine/glycopyrrolate, sugammadex
Drug
Lead sponsor
Temple University
Other
Eligibility
18 Years to 89 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 12, 2024 · Synced May 22, 2026, 2:44 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Invasive Mechanical Ventilation, Critical Illness, Spontaneous Breathing Trial, Weaning Invasive Mechanical Ventilation, Tracheostomy, Direct Extubation
Interventions
Not listed
Lead sponsor
Unity Health Toronto
Other
Eligibility
16 Years and older
Enrollment
1,868 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
2
States / cities
Boston, Massachusetts • Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 1, 2021 · Synced May 22, 2026, 2:44 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Respiratory Distress Syndrome (RDS), PreTerm Neonate
Interventions
Observation
Other
Lead sponsor
Christiana Care Health Services
Other
Eligibility
0 Days to 6 Months
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced May 22, 2026, 2:44 AM EDT
Terminated Phase 4 Interventional Results available
View directory record Official record
Conditions
Adenotonsillar Hypertrophy, Obstructive Sleep Apnea, Tonsillitis, Adenoiditis
Interventions
Normal Saline, Dexmedetomidine
Drug
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
3 Years to 16 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 8, 2020 · Synced May 22, 2026, 2:44 AM EDT
Completed No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Anesthesia Complication
Interventions
Not listed
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 22, 2020 · Synced May 22, 2026, 2:44 AM EDT
Withdrawn No phase listed Observational
View directory record Official record
Conditions
Respiratory Insufficiency
Interventions
Not listed
Lead sponsor
Rush University Medical Center
Other
Eligibility
1 Year to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 27, 2022 · Synced May 22, 2026, 2:44 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Respiratory Distress Syndrome
Interventions
HHHFNC, NCPAP
Device
Lead sponsor
Sidra Medicine
Other
Eligibility
Not listed
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Akron, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 26, 2015 · Synced May 22, 2026, 2:44 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Anesthesia
Interventions
Sufentanil Infusion, Sufentanil Bolus
Drug
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years to 80 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Dec 10, 2024 · Synced May 22, 2026, 2:44 AM EDT
Withdrawn Not applicable Interventional
View directory record Official record
Conditions
Extubation
Interventions
ENLIGHT 2100 ventilatory electrical impedance tomograph
Device
Lead sponsor
Duke University
Other
Eligibility
Up to 17 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced May 22, 2026, 2:44 AM EDT
Withdrawn Not applicable Interventional
View directory record Official record
Conditions
Mechanical Ventilation, Corona Virus Infection
Interventions
Helmet non-invasive ventilation (NIV)
Device
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 1, 2024 · Synced May 22, 2026, 2:44 AM EDT
Completed Phase 4 Interventional Results available
View directory record Official record
Conditions
Surgery, Coronary Artery Disease
Interventions
Rocuronium, Neostigmine, Glycopyrrolate, Sugammadex
Drug
Lead sponsor
West Virginia University
Other
Eligibility
18 Years to 70 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Dec 26, 2023 · Synced May 22, 2026, 2:44 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Mechanical Ventilation Complication, Extubation
Interventions
IPI monitoring
Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
174 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 7, 2021 · Synced May 22, 2026, 2:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Anesthesia, Laryngospasm on Emergence
Interventions
Pupillometry
Diagnostic Test
Lead sponsor
University of California, San Francisco
Other
Eligibility
2 Years to 10 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Oakland, California
Source: ClinicalTrials.gov public record
Updated Jan 21, 2025 · Synced May 22, 2026, 2:44 AM EDT