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Showing 25–44 of 20 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Facet Joint Pain Clear all
Terminated Phase 1 Interventional

Study Evaluating the Safety and Feasibility of Platelet-rich Plasma to Treat Facetogenic Low Back Pain

NCT05250947
View directory record Official record
Conditions
Lumbar Spondylosis
Interventions
Angel® Concentrated Platelet Rich Plasma System, Platelet Rich Plasma
Device · Drug
Lead sponsor
Matthew Pingree
Other
Eligibility
22 Years to 70 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 16, 2024 · Synced Jul 23, 2026, 8:52 AM EDT
Completed Not applicable Interventional Results available

Efficacy and Cost: Benefit Ratio of 0, 1, and 2 Medial Branch Blocks for Lumbar Facet Joint Radiofrequency Denervation

NCT00484159
View directory record Official record
Conditions
Low Back Pain
Interventions
Radiofrequency denervation of medial branches, 0.5% bupivacaine, 2% lidocaine, Radiofrequency denervation
Procedure · Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 25, 2011 · Synced Jul 23, 2026, 8:52 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Lazanda Fentanyl Nasal Spray Pre Radiofrequency Nerve Ablations(RFA) of Lumbar Facet Joints

NCT02571634
View directory record Official record
Conditions
Minor Procedural Pain
Interventions
Lazanda
Drug
Lead sponsor
Defense and Veterans Center for Integrative Pain Management
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Fort Bragg, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 24, 2016 · Synced Jul 23, 2026, 8:52 AM EDT
Recruiting Not applicable Interventional

Trans-arterial Embolization for the Treatment of Facet Pain Due to Facet Arthropathy

NCT06965452
View directory record Official record
Conditions
Facet Joint Arthropathy, Pain, Osteoarthritis
Interventions
Spinal angiography and embolization/ Embozene Microspheres
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Aug 18, 2025 · Synced Jul 23, 2026, 8:52 AM EDT
Recruiting Phase 1 Interventional

Safety and Feasibility of Umbilical Cord Wharton's Jelly Allograft Injections for Lumbar Pain

NCT06361485
View directory record Official record
Conditions
Low Back Pain
Interventions
Lumbar Injections with 10cc's of Wharton's Jelly Allograft
Biological
Lead sponsor
R3 Stem Cell
Industry
Eligibility
20 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
4
States / cities
Scottsdale, Arizona • Beverly Hills, California • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 10, 2024 · Synced Jul 23, 2026, 8:52 AM EDT
Withdrawn Not applicable Interventional

MR Guided High Intensity Focused Ultrasound for Lumbar Back Pain

NCT02291978
View directory record Official record
Conditions
Lumbar Facet Joint Pain
Interventions
ExAblate 2100
Device
Lead sponsor
Stanford University
Other
Eligibility
21 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 23, 2020 · Synced Jul 23, 2026, 8:52 AM EDT
Completed Not applicable Interventional

Z-Joint Changes in Low Back Pain Following Adjusting

NCT00284063
View directory record Official record
Conditions
Mechanical Low Back Pain
Interventions
Low back adjustment and MRI, MRI
Procedure
Lead sponsor
National University of Health Sciences
Other
Eligibility
21 Years to 69 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Lombard, Illinois
Source: ClinicalTrials.gov public record
Updated May 11, 2022 · Synced Jul 23, 2026, 8:52 AM EDT
Completed Not applicable Interventional

Platelet Rich Plasma (PRP) for Facet Mediated Lumbar Low Back Pain

NCT04822753
View directory record Official record
Conditions
Facet Joint Pain; Low Back Pain
Interventions
Platelet Rich Plasma injection to the lumbar facet joint
Procedure
Lead sponsor
Womack Army Medical Center
Federal
Eligibility
18 Years to 75 Years
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Fort Liberty, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 10, 2025 · Synced Jul 23, 2026, 8:52 AM EDT
Completed Not applicable Interventional Results available

Effectiveness of Lumbar Facet Joint Nerve Blocks

NCT00355914
View directory record Official record
Conditions
Low Back Pain
Interventions
Lumbar Facet Joint Nerve Block
Procedure
Lead sponsor
Pain Management Center of Paducah
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
1
States / cities
Paducah, Kentucky
Source: ClinicalTrials.gov public record
Updated Nov 25, 2013 · Synced Jul 23, 2026, 8:52 AM EDT
Active, not recruiting Phase 2 Interventional

Allogeneic BM-MSCs in Patients With Painful Lumbar Facet Arthropathy

NCT06001853
View directory record Official record
Conditions
Facet-Mediated Low Back Pain, Lumbar Facet Joint Osteoarthritis
Interventions
BM-MSC injection, DSMO Injection
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Jul 23, 2026, 8:52 AM EDT
Completed Not applicable Interventional Results available

Effectiveness of Thoracic Facet Joint Nerve Blocks

NCT00355706
View directory record Official record
Conditions
Low Back Pain
Interventions
Thoracic facet joint nerve blocks
Procedure
Lead sponsor
Pain Management Center of Paducah
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2011
U.S. locations
1
States / cities
Paducah, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 9, 2020 · Synced Jul 23, 2026, 8:52 AM EDT
Terminated Not applicable Interventional

A Multi-Site Study of the Zyga GlyDer Facet Restoration Device In Subjects With LUmbar FacET Pain Syndrome - DUET

NCT02179476
View directory record Official record
Conditions
Facet Joint Pain
Interventions
Glyder
Device
Lead sponsor
Zyga Technology, Inc.
Industry
Eligibility
22 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
4
States / cities
Santa Monica, California • Tampa, Florida • Edmond, Oklahoma + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 10, 2018 · Synced Jul 23, 2026, 8:52 AM EDT
Not listed No phase listed Observational

Technical Description of Cooled Radiofrequency Ablation of Lumbar Medial Branches for the Treatment of Lumbar Facet Pain

NCT01590004
View directory record Official record
Conditions
Lumbar Facet Joint Pain
Interventions
Not listed
Lead sponsor
Mehul Desai
Industry
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
1
States / cities
Edina, Minnesota
Source: ClinicalTrials.gov public record
Updated May 18, 2015 · Synced Jul 23, 2026, 8:52 AM EDT
Not listed Not applicable Interventional

Cooled RFA vs Conventional RFA to Manage Chronic Facetogenic Low Back Pain

NCT04803149
View directory record Official record
Conditions
Chronic Low-back Pain
Interventions
Cooled Radiofrequency, Conventional Radiofrequency
Device
Lead sponsor
Avanos Medical
Other
Eligibility
21 Years and older
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
10
States / cities
Washington D.C., District of Columbia • Bloomington, Illinois • New Orleans, Louisiana + 7 more
Source: ClinicalTrials.gov public record
Updated Jun 29, 2022 · Synced Jul 23, 2026, 8:52 AM EDT
Suspended Not applicable Interventional

PNS vs RFA for Facet Joint Pain

NCT05952518
View directory record Official record
Conditions
Facet Joint Pain
Interventions
Sprint PNS system, Radiofrequency Ablation
Device · Procedure
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 80 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Jul 23, 2026, 8:52 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Analysis of Crepitus in Human Subjects

NCT05425017
View directory record Official record
Conditions
Low Back Pain, Healthy
Interventions
Range of motion with spinal adjustment
Other
Lead sponsor
National University of Health Sciences
Other
Eligibility
30 Years to 75 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
2
States / cities
Lombard, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 4, 2024 · Synced Jul 23, 2026, 8:52 AM EDT
Completed Not applicable Interventional Results available

Effectiveness of Cervical Facet Joint Nerve Blocks

NCT00332722
View directory record Official record
Conditions
Neck Pain
Interventions
Cervical facet joint nerve blocks
Procedure
Lead sponsor
Pain Management Center of Paducah
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
Paducah, Kentucky
Source: ClinicalTrials.gov public record
Updated Sep 30, 2013 · Synced Jul 23, 2026, 8:52 AM EDT
Not listed No phase listed Observational

Injections of FloGraft Therapy, Autologous Stem Cells, or Platelet Rich Plasma for the Treatment of Degenerative Joint Pain

NCT01978639
View directory record Official record
Conditions
Osteoarthritis, Rheumatoid Arthritis
Interventions
Not listed
Lead sponsor
Arizona Pain Specialists
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2014
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated May 24, 2017 · Synced Jul 23, 2026, 8:52 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Using MRI Scans to Evaluate Spinal Manipulation

NCT00070902
View directory record Official record
Conditions
Lower Back Pain
Interventions
Lumbar side-posture spinal adjusting
Procedure
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
21 Years to 29 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2002
U.S. locations
1
States / cities
Lombard, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 17, 2006 · Synced Jul 23, 2026, 8:52 AM EDT
Completed Early Phase 1 Interventional

Intraarticular Lumbar Joint Corticosteroid Injection(s) as a Treatment of Chronic Low Back Pain in a Selected Population

NCT01382771
View directory record Official record
Conditions
Low Back Pain
Interventions
Intra-articular corticosteroid injection, Intra-articular saline injection
Drug
Lead sponsor
University of Florida
Other
Eligibility
45 Years to 90 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 13, 2013 · Synced Jul 23, 2026, 8:52 AM EDT