- Conditions
- Gustilo-Anderson Type III Open Tibia Fracture
- Interventions
- Irrisept (Irrigation Solution), Saline
- Drug
- Lead sponsor
- Brett D. Crist
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Columbia, Missouri
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Showing 25–48
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- Conditions
- Tibial Shaft Fractures
- Interventions
- Carbon Fiber Implant, Titanium Implant
- Device
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2021
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
- Conditions
- Osteomyelitis Tibia, Tibial Fractures, Open Tibia Fracture
- Interventions
- Antibiotic coated intramedullary Nail, Standard Intramedullary Nail
- Drug · Other
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 484 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 14
- States / cities
- Gainesville, Florida • Temple Terrace, Florida • Macon, Georgia + 11 more
- Conditions
- Fractures
- Interventions
- rhBMP-2/CPM
- Drug
- Lead sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 367 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2010
- U.S. locations
- 17
- States / cities
- Birmingham, Alabama • Aurora, Colorado • Denver, Colorado + 13 more
- Conditions
- Fractures, Bone, Fractures, Closed, Fractures, Open, Fracture of Femur, Fracture Nonunion, Fracture of Tibia, Limb Deformity, Limb Fracture, Limb Defect, Limb Asymmetry
- Interventions
- Fitbone Transport and Lengthening System
- Device
- Lead sponsor
- Orthofix Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 9
- States / cities
- Los Angeles, California • Orange, California • Atlanta, Georgia + 6 more
- Conditions
- Tibia Fracture
- Interventions
- Ibuprofen
- Drug
- Lead sponsor
- Major Extremity Trauma Research Consortium
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 1,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- Salt Lake City, Utah
- Conditions
- Ankle Fracture, Malleolus Fracture, Medial Malleolus Fracture, Bimalleolar Fracture, Trimalleolar Fracture
- Interventions
- Nonsurgical, Surgical
- Procedure
- Lead sponsor
- University of Tennessee
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2019
- U.S. locations
- 1
- States / cities
- Chattanooga, Tennessee
- Conditions
- Wrist Injury, Tibial Fracture, Hip Injury
- Interventions
- Standard X-Ray + CT, Standard X-Ray + MRI, TOMO
- Device
- Lead sponsor
- Fujifilm Medical Systems USA, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 1
- States / cities
- Maywood, Illinois
- Conditions
- Intraarticular Fracture and Post-traumatic Osteoarthritis
- Interventions
- Not listed
- Lead sponsor
- University of Utah
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2028
- U.S. locations
- 1
- States / cities
- Salt Lake City, Utah
- Conditions
- Congenital Pseudarthrosis of Tibia
- Interventions
- NVD003, Iliac Crest Bone Graft
- Biological · Procedure
- Lead sponsor
- Novadip Biosciences
- Industry
- Eligibility
- Up to 17 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 4
- States / cities
- Phoenix, Arizona • Loma Linda, California • Baltimore, Maryland + 1 more
- Conditions
- Acute Tibial Fracture Requiring Intramedullary Nailing
- Interventions
- Intramedullary nailing of the tibia
- Procedure
- Lead sponsor
- University of Pennsylvania
- Other
- Eligibility
- 21 Years to 50 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2020
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Pain, Postoperative
- Interventions
- Methadone, Morphine
- Drug
- Lead sponsor
- Baylor College of Medicine
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 17 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2014
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Fractures, Bone, Nonunion of Fracture, Fractures, Open, Fractures, Ununited, Fracture, Tibial, Fracture of Femur, Fracture Arm
- Interventions
- Vivigen Cellular Bone Matrix
- Other
- Lead sponsor
- LifeNet Health
- Industry
- Eligibility
- Not listed
- Enrollment
- 250 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2026
- U.S. locations
- 4
- States / cities
- Orlando, Florida • Jersey City, New Jersey • Durham, North Carolina + 1 more
- Conditions
- Tibia Fracture, Humerus Fracture, Femoral Fracture, Long Bone Segmental Defect
- Interventions
- TRUMATCH Graft Cage
- Procedure
- Lead sponsor
- University of California, San Diego
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 5 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2026
- U.S. locations
- 1
- States / cities
- San Diego, California
- Conditions
- Tibial Plateau Fracture, Pain, Postoperative
- Interventions
- Duloxetine, Placebo, Standard of care (SOC) for tibial plateau surgery
- Drug · Other
- Lead sponsor
- Boston Medical Center
- Other
- Eligibility
- 18 Years to 80 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 2
- States / cities
- Boston, Massachusetts • Valhalla, New York
- Conditions
- Tibial Shaft Fracture, Tibial Plateau Fracture
- Interventions
- Acute injury without compartment syndrome, Acute injury with compartment syndrome, Exertional compartment syndrome
- Procedure
- Lead sponsor
- University of Utah
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 80 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2028
- U.S. locations
- 1
- States / cities
- Salt Lake City, Utah
- Conditions
- Open Tibia Fracture, Open Dislocation of Ankle, Extremity Fracture Lower, Extremity Injuries Lower
- Interventions
- Accelerated Flap Coverage Surgery, Standard of Care Flap Timing
- Procedure
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 356 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2030
- U.S. locations
- 7
- States / cities
- Sacramento, California • Baltimore, Maryland • Largo, Maryland + 2 more
- Conditions
- Metatarsal Stress Fracture, Stress Fracture of Tibia
- Interventions
- Photobiomodulation Therapy with Standard Physical Therapy, Sham Photobiomodulation Therapy with Standard Physical Therapy
- Device · Other
- Lead sponsor
- Brooke Army Medical Center
- Federal
- Eligibility
- 17 Years to 64 Years
- Enrollment
- 103 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- San Antonio, Texas
- Conditions
- Tibial Fracture
- Interventions
- Intramedullary nail implant
- Procedure
- Lead sponsor
- University of Minnesota
- Other
- Eligibility
- 16 Years and older
- Enrollment
- 1,200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2002 – 2006
- U.S. locations
- 16
- States / cities
- San Francisco, California • Jacksonville, Florida • Evansville, Indiana + 13 more
- Conditions
- Tibial Fracture, Fracture of the Tibia Type AO/OTA 42
- Interventions
- Surgery
- Procedure
- Lead sponsor
- AO Clinical Investigation and Publishing Documentation
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2025
- U.S. locations
- 3
- States / cities
- New York, New York • Nashville, Tennessee
- Conditions
- Femur Fracture, Tibial Fractures, Nonunion of Fracture, Nonunion of Fracture of Tibia, Nonunion of Fracture of Femur (Diagnosis), Tibia Fracture
- Interventions
- Distal targeting jig, Free-hand/perfect circles technique
- Device · Procedure
- Lead sponsor
- Cedars-Sinai Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 89 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Hip Fractures, Tibial Fractures, Ankle Fractures, Humeral Fracture, Proximal, Distal Radius Fracture
- Interventions
- All treatments will remain the standard (routine) care procedures based on individual clinician's judgment and the patient characteristics.
- Other
- Lead sponsor
- AO Innovation Translation Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1,500 participants
- Timeline
- 2021 – 2026
- U.S. locations
- 4
- States / cities
- Los Angeles, California • Miami, Florida • Boston, Massachusetts + 1 more
- Conditions
- Distal Femur Fracture, Tibial Plateau Fracture, Distal Tibia Fracture, Pilon Fracture
- Interventions
- AlterG anti-gravity treadmill
- Other
- Lead sponsor
- Major Extremity Trauma Research Consortium
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 81 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2022
- U.S. locations
- 10
- States / cities
- San Diego, California • San Francisco, California • Lexington, Kentucky + 7 more
- Conditions
- Equinus Contracture
- Interventions
- Botulinum toxin type A, sodium chloride
- Drug
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2016
- U.S. locations
- 1
- States / cities
- Charlotte, North Carolina