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ClinicalTrials.gov public records Last synced May 21, 2026, 8:59 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Frailty Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Aging
Interventions
Cafe Move
Behavioral
Lead sponsor
University of Montana
Other
Eligibility
50 Years to 85 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Missoula, Montana
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced May 21, 2026, 8:59 PM EDT
Completed No phase listed Observational Results available
View directory record Official record
Conditions
Herpes Zoster
Interventions
Encoding of data collected in Zoster 006 and Zoster 022 studies
Other
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
50 Years and older
Enrollment
26,976 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
31
States / cities
Mesa, Arizona • Phoenix, Arizona • Spring Valley, California + 26 more
Source: ClinicalTrials.gov public record
Updated Apr 29, 2020 · Synced May 21, 2026, 8:59 PM EDT
Not listed Early Phase 1 Interventional
View directory record Official record
Conditions
Cirrhosis, Liver, Sarcopenia
Interventions
Transjugular Intrahepatic Portosystemic Shunt (TIPS) creation
Procedure
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 99 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 6, 2023 · Synced May 21, 2026, 8:59 PM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Frailty, Pain, Chronic, Dialysis; Complications, Kidney Diseases
Interventions
Muscle Therapy
Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 13, 2025 · Synced May 21, 2026, 8:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
HIV
Interventions
Digital Activity Tracker, Smart Text Messaging, Physical Activity Counseling
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 4, 2022 · Synced May 21, 2026, 8:59 PM EDT
Completed Phase 1Phase 2 Interventional
View directory record Official record
Conditions
Aging Frailty
Interventions
Longeveron Mesenchymal Stem Cells (LMSCs), Fluzone High Dose Vaccine
Biological
Lead sponsor
Longeveron Inc.
Industry
Eligibility
65 Years to 90 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
6
States / cities
Coral Gables, Florida • Fort Myers, Florida • Miami, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 3, 2022 · Synced May 21, 2026, 8:59 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Frailty
Interventions
Physical Therapy
Other
Lead sponsor
University of Chicago
Other
Eligibility
60 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 25, 2023 · Synced May 21, 2026, 8:59 PM EDT
Completed Phase 2 Interventional
View directory record Official record
Conditions
Sarcopenia, Muscle Weakness, Frailty
Interventions
Topical testosterone, Recombinant human growth hormone
Drug
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
65 Years to 90 Years · Male only
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2007
U.S. locations
2
States / cities
Boston, Massachusetts • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 1, 2009 · Synced May 21, 2026, 8:59 PM EDT
Withdrawn Phase 1Phase 2 Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Frailty
Interventions
Mesenchymal Stem Cells (MSCs)
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
65 Years to 85 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 5, 2023 · Synced May 21, 2026, 8:59 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Toileting Disability, Functional Urinary Incontinence
Interventions
Defeating Urinary Incontinence with Exercise Training
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
60 Years and older · Female only
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 5, 2019 · Synced May 21, 2026, 8:59 PM EDT
Terminated Not applicable Interventional Results available
View directory record Official record
Conditions
Frailty, Disability or Chronic Disease Leading to Disablement
Interventions
3-Step Workout for Life
Other
Lead sponsor
University of Florida
Other
Eligibility
65 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 2, 2025 · Synced May 21, 2026, 8:59 PM EDT
Enrolling by invitation Not applicable Interventional
View directory record Official record
Conditions
Frailty, Ventral Hernia
Interventions
Prehabilitation, Standard of Care (SOC)
Behavioral · Other
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
65 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced May 21, 2026, 8:59 PM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Frailty, Cancer, Chemotherapy-Induced Change
Interventions
Not listed
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years and older
Enrollment
141 participants
Timeline
2021 – 2023
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 17, 2023 · Synced May 21, 2026, 8:59 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Frail Elderly, Aging, Immune Function, Muscle Function
Interventions
Ketone ester, Placebo Comparator: Non-ketone placebo
Other
Lead sponsor
Buck Institute for Research on Aging
Other
Eligibility
65 Years and older
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
3
States / cities
Novato, California • Farmington, Connecticut • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced May 21, 2026, 8:59 PM EDT
Completed Phase 2 Interventional Results available
View directory record Official record
Conditions
Frailty Syndrome
Interventions
Ghrelin, Placebo
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
70 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 10, 2019 · Synced May 21, 2026, 8:59 PM EDT
Recruiting Phase 2 Interventional
View directory record Official record
Conditions
Anatomic Stage I Breast Cancer American Joint Committee on Cancer (AJCC) v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Early Stage Breast Carcinoma
Interventions
Biospecimen Collection, Educational Intervention, Exercise Intervention, Fisetin, Physical Performance Testing, Placebo Administration, Quality-of-Life Assessment, Questionnaire Administration
Procedure · Other · Drug
Lead sponsor
Jonsson Comprehensive Cancer Center
Other
Eligibility
Female only
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
6
States / cities
Alhambra, California • Beverly Hills, California • Burbank, California + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 7, 2025 · Synced May 21, 2026, 8:59 PM EDT
Active, not recruiting Not applicable Interventional
View directory record Official record
Conditions
Aging, Heart Failure With Preserved Ejection Fraction, Heart Failure With Reduced Ejection Fraction, Frailty, Physical Function, Quality of Life
Interventions
Inspiratory Muscle Training (IMT), Standard of Care
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
70 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 3, 2025 · Synced May 21, 2026, 8:59 PM EDT
Completed Phase 2 Interventional
View directory record Official record
Conditions
Sarcopenia, Frailty, Aging
Interventions
MYMD-1 600MG, MYMD-1 750mg, MYMD-1 900mg, MYMD-1 1050mg, placebo 600mg, placebo 750mg, placebo 900mg, placebo 1050mg
Drug
Lead sponsor
TNF Pharmaceuticals, Inc.
Industry
Eligibility
65 Years to 99 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
3
States / cities
Clearwater, Florida • Tampa, Florida • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 29, 2023 · Synced May 21, 2026, 8:59 PM EDT
Recruiting No phase listed Observational
View directory record Official record
Conditions
Gastrointestinal Cancer
Interventions
Frailty survey
Other
Lead sponsor
The Guthrie Clinic
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
East Corning, New York • Sayre, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced May 21, 2026, 8:59 PM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Frailty
Interventions
Meals plus exercise, Meals only
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
60 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 7, 2023 · Synced May 21, 2026, 8:59 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Aging, Aging Well, All-Cause Mortality, Mortality, Metabolic Syndrome, Cardiovascular Diseases, Cognitive Dysfunction, Musculoskeletal Diseases, Neoplasms, Frailty, Activities of Daily Living, Health-Related Quality of Life, Disability Physical, Neuro-Degenerative Disease, Dementia
Interventions
Comprehensive Multi-System Clinical Screening
Diagnostic Test
Lead sponsor
Longevity Metrics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
10,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2099
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced May 21, 2026, 8:59 PM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Kidney Transplant; Complications, Dialysis; Complications, Physical Disability, Frailty Syndrome
Interventions
Structured Program of exercise for Recipients of Kidney Transplantation (WC), Structured Program of exercise for Recipients of Kidney Transplantation (WC + CG), Usual Care
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
50 Years and older
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2029
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 15, 2023 · Synced May 21, 2026, 8:59 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Liver Diseases, End Stage Liver Disease, Frailty
Interventions
Nokia GO Wearable StepTracker, Medication Reminder, Weekly Check-in appointment with study team or provider
Device · Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
21 Years to 95 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 10, 2023 · Synced May 21, 2026, 8:59 PM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Effects of Chemotherapy, Aging, Frailty
Interventions
Geriatric Assessments and Frailty Indices
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
65 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 31, 2025 · Synced May 21, 2026, 8:59 PM EDT