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Filters: Condition: Functional Constipation in Children Ages 6-17 Years Clear all

Terminated Phase 2 Interventional Results available

A Safety and Efficacy Study of a Range of Linaclotide Doses Administered Orally to Children Ages 7-17 Years, With Irritable Bowel Syndrome With Constipation

NCT02559817

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Conditions: Irritable Bowel Syndrome With Constipation
Interventions: Linaclotide Dose A, Linaclotide Dose B, Linaclotide Dose C, Linaclotide Approved Adult Dose, Matching Placebo; Drug
Lead sponsor: Forest Laboratories; Industry
Eligibility: 7 Years to 17 Years

Enrollment: 101 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 46
States / cities: Hot Springs, Arkansas • Little Rock, Arkansas • Anaheim, California + 39 more

Source: ClinicalTrials.gov public record

Updated Dec 27, 2020 · Synced May 22, 2026, 4:15 AM EDT

Completed Phase 2 Interventional Results available

A Safety and Efficacy Study of a Range of Linaclotide Doses Administered Orally to Children Ages 6-17 Years Who Fulfill Modified Rome III Criteria for Child/Adolescent Functional Constipation (FC)

NCT02559570

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Conditions: Functional Constipation in Children Ages 6-17 Years
Interventions: Placebo, LIN Dose A, LIN Dose B, LIN Dose C, LIN 145 µg; Drug
Lead sponsor: Forest Laboratories; Industry
Eligibility: 6 Years to 17 Years

Enrollment: 173 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 60
States / cities: Hot Springs, Arkansas • Little Rock, Arkansas • Anaheim, California + 51 more

Source: ClinicalTrials.gov public record

Updated Jun 18, 2019 · Synced May 22, 2026, 4:15 AM EDT

Completed Phase 3 Interventional Results available

Linaclotide Safety and Efficacy in Pediatric Participants, 6 to 17 Years of Age, With Irritable Bowel Syndrome With Constipation (IBS-C) or Functional Constipation (FC)

NCT04026113

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Conditions: Functional Constipation, Irritable Bowel Syndrome With Constipation
Interventions: Linaclotide, Placebo; Drug
Lead sponsor: AbbVie; Industry
Eligibility: 6 Years to 17 Years

Enrollment: 438 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 79
States / cities: Birmingham, Alabama • Foley, Alabama • Saraland, Alabama + 62 more

Source: ClinicalTrials.gov public record

Updated Nov 25, 2024 · Synced May 22, 2026, 4:15 AM EDT