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ClinicalTrials.gov public records Last synced May 22, 2026, 3:37 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Functional Joint Pain Clear all
Completed Phase 3 Interventional Results available
View directory record Official record
Conditions
Osteoarthritis of the Knee, Coagulopathy
Interventions
Pennsaid
Drug
Lead sponsor
Nathan Wei, MD, FACP, FACR:
Other
Eligibility
55 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Frederick, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 25, 2014 · Synced May 22, 2026, 3:37 AM EDT
Withdrawn Phase 1Phase 2 Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Osteoarthritis of the Knee, Degenerative Osteoarthritis, Knee Pain Chronic
Interventions
Ibuprofen and PRP, Acetaminophen and PRP, Placebo and PRP
Combination Product
Lead sponsor
QC Kinetix LLC
Industry
Eligibility
50 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 8, 2024 · Synced May 22, 2026, 3:37 AM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Activity-Related Knee Discomfort, Joint Discomfort, Functional Joint Pain, Functional Knee Pain, Knee Acute and Chronic Pain
Interventions
NT-II™ (240 mg), NT-II™ 480 mg, Glucosamine/Chondroitin
Dietary Supplement
Lead sponsor
Hofseth Biocare ASA
Industry
Eligibility
20 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced May 22, 2026, 3:37 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Shoulder Pain, Osteoarthritis of Glenohumeral Joint, Rotator Cuff Tear Arthropathy
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
1,034 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2024
U.S. locations
2
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 12, 2025 · Synced May 22, 2026, 3:37 AM EDT
Completed Phase 4 Interventional
View directory record Official record
Conditions
Knee Discomfort, Pain Physical Activity
Interventions
Polyherbal capsule, Placebo capsule
Dietary Supplement
Lead sponsor
NewChapter, Inc.
Industry
Eligibility
25 Years to 75 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
5
States / cities
Homestead, Florida • Duncansville, Pennsylvania • Dallas, Texas + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 13, 2015 · Synced May 22, 2026, 3:37 AM EDT
Completed Phase 2 Interventional
View directory record Official record
Conditions
Osteoarthritis
Interventions
Shock Absorbing Insole (SofSole Athletes Plus)
Other
Lead sponsor
Winston Salem State University
Other
Eligibility
50 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 22, 2013 · Synced May 22, 2026, 3:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Home-based Neuromuscular Electrical Stimulation (NMES) therapy
Device
Lead sponsor
CyMedica Orthopedics, Inc
Industry
Eligibility
21 Years and older
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
5
States / cities
Tucson, Arizona • Houston, Texas • Katy, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 17, 2021 · Synced May 22, 2026, 3:37 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Effusion Joint
Interventions
Arthrocentesis
Procedure
Lead sponsor
Colorado Joint Replacement
Other
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
2
States / cities
Aurora, Colorado • Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 30, 2023 · Synced May 22, 2026, 3:37 AM EDT
Suspended No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Chronic Pancreatitis, Inflammatory Bowel Diseases, Hepatitis, NASH - Nonalcoholic Steatohepatitis, Acute Pancreatitis, Rheumatoid Arthritis, Diabetes Mellitus, Dyslipidemias, Multiple Sclerosis, Irritable Bowel Syndrome, Chronic Pain, Chronic Disease, Chronic Kidney Diseases, Crohn Disease, Celiac Disease, Biliary Cirrhosis, Bile Acid Synthesis Defect, Gastritis, Cholecystitis, Cholelithiases, IPMN, Cyst Pancreas, Cystic Fibrosis, Pancreatic Exocrine Insufficiency, Diarrhea Chronic, Constipation - Functional, Constipation Chronic Idiopathic
Interventions
venipuncture, Questionnaires, Additional Sample Collections
Other · Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
12 Years and older
Enrollment
120,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced May 22, 2026, 3:37 AM EDT
Terminated Not applicable Interventional Results available
View directory record Official record
Conditions
Osteoarthritis, Osteoarthritis, Knee
Interventions
12-week exercise and walking program, NMES, FES
Other · Device
Lead sponsor
Cionic, Inc.
Industry
Eligibility
22 Years to 75 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 2, 2025 · Synced May 22, 2026, 3:37 AM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Patellofemoral Pain Syndrome
Interventions
transcranial direct current stimulator
Device
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years to 45 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Aug 21, 2024 · Synced May 22, 2026, 3:37 AM EDT
Not listed Phase 1Phase 2 Interventional
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Bone Marrow Derived MSCs, Corticosteroid, Bone Marrow Aspirate
Biological · Drug · Device
Lead sponsor
Next Generation Regenerative Medicine LLC
Network
Eligibility
18 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
3
States / cities
Chesterfield, Missouri • Steubenville, Ohio • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Mar 20, 2022 · Synced May 22, 2026, 3:37 AM EDT
Completed Phase 2 Interventional
View directory record Official record
Conditions
Osteoarthritis
Interventions
periosteal electro-acupuncture (osteopuncture).
Device
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
65 Years and older
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 31, 2006 · Synced May 22, 2026, 3:37 AM EDT
Active, not recruiting No phase listed Interventional Results available
View directory record Official record
Conditions
Chronic Pain, Osteoarthritis
Interventions
active low-intensity transcranial electrical stimulation/active transcranial ultrasound, Sham low-intensity transcranial electrical stimulation/sham transcranial ultrasound
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 85 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 28, 2025 · Synced May 22, 2026, 3:37 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Rheumatoid Arthritis, Diabetic Neuropathy, Fibromyalgia, Irritable Bowel Syndrome
Interventions
DiNaMo Study App, Placebo App
Device
Lead sponsor
Click Therapeutics, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 25, 2023 · Synced May 22, 2026, 3:37 AM EDT
Not listed Not applicable Interventional
View directory record Official record
Conditions
Arthritis, Asthma, Chronic Obstructive Lung Disease, Diabetes, Heart Failure, Hypertension, Anxiety, Chronic Pain, Depression, Fibromyalgia, Insomnia, Irritable Bowel Syndrome, Problem Drinking, Substance Use Disorder
Interventions
Integration
Other
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
4,025 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Oct 4, 2021 · Synced May 22, 2026, 3:37 AM EDT
Completed No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Central Nervous System Sensitization
Interventions
Posturography Evaluation, Central Sensitization Inventory
Diagnostic Test · Other
Lead sponsor
Caps Research Network
Other
Eligibility
18 Years to 65 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Marietta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 3, 2021 · Synced May 22, 2026, 3:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Osteoarthritis
Interventions
Knee injection, ReNu amniotic allograft, placebo saline, Hyaluronic Acid
Procedure · Other · Device
Lead sponsor
NuTech Medical, Inc
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
12
States / cities
Birmingham, Alabama • Los Angeles, California • Chicago, Illinois + 8 more
Source: ClinicalTrials.gov public record
Updated Jan 17, 2020 · Synced May 22, 2026, 3:37 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Hybrid Training using Electrodes and Joint Motion Sensors, Isokinetic Training with Isokinetic Dynamometer
Device
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
40 Years to 85 Years · Female only
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated May 17, 2018 · Synced May 22, 2026, 3:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Allergic Rhinitis, Asthma, Back Pain, Benign Prostatic Hypertrophy, Bursitis, Depression, Anxiety, Diabetes Mellitus, Esophageal Reflux, HIV Infections, Hyperlipidemia, Hypertension, Insomnia, Irritable Bowel Syndrome, Obesity, Osteoporosis (Senile), Shoulder Pain, Sinusitis, Symptomatic Menopause, Urinary Incontinence, Urinary Tract Infection, Vaginitis
Interventions
Health Information Prescription
Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
224 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 29, 2016 · Synced May 22, 2026, 3:37 AM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Arthritis
Interventions
Functional Exercise for People with Arthritis (FEPA)
Behavioral
Lead sponsor
Centers for Disease Control and Prevention
Federal
Eligibility
20 Years to 85 Years
Enrollment
154 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 9, 2007 · Synced May 22, 2026, 3:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Osteoarthritis
Interventions
Limitation of Animal Fat and Protein in the Diet, Control
Other
Lead sponsor
Essentia Health
Other
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Traverse City, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 19, 2013 · Synced May 22, 2026, 3:37 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Patellofemoral Pain Syndrome
Interventions
Lumbopelvic Manipulation, Passive lumbar spine flexion and extension
Other
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years to 50 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 11, 2015 · Synced May 22, 2026, 3:37 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Knee Injuries, Knee Osteoarthritis
Interventions
Cutaneous Stimulation, Knee Sleeve
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 80 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 16, 2021 · Synced May 22, 2026, 3:37 AM EDT