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ClinicalTrials.gov public records Last synced May 22, 2026, 1:18 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 32 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Gender Dysphoria Clear all
Completed No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Gender Dysphoria
Interventions
Not listed
Lead sponsor
Mountain Dermatology Specialists
Other
Eligibility
18 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 19, 2020 · Synced May 22, 2026, 1:18 AM EDT
Recruiting No phase listed Observational
View directory record Official record
Conditions
Transgenderism, Gender Dysphoria, Insulin Sensitivity
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
13 Years to 16 Years
Enrollment
90 participants
Timeline
2021 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 9, 2025 · Synced May 22, 2026, 1:18 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Gender Dysphoria
Interventions
17beta Estradiol
Drug
Lead sponsor
MaineHealth
Other
Eligibility
18 Years and older · Male only
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Portland, Maine
Source: ClinicalTrials.gov public record
Updated Jul 26, 2023 · Synced May 22, 2026, 1:18 AM EDT
Not yet recruiting No phase listed Observational
View directory record Official record
Conditions
Vaginoplasty, Gender Dysphoria, Adult
Interventions
Use 3D printed patient specific models for patient education
Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older · Male only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced May 22, 2026, 1:18 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Gender Identity, Gender Dysphoria, Gender Identity Disorder in Adolescence and Adulthood
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
13 Years to 16 Years · Female only
Enrollment
19 participants
Timeline
2018 – 2020
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 28, 2020 · Synced May 22, 2026, 1:18 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Gender Dysphoria
Interventions
fMRI
Diagnostic Test
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 40 Years
Enrollment
132 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 21, 2023 · Synced May 22, 2026, 1:18 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Gender Dysphoria
Interventions
Mastectomy and chest masculinization
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
13 Years to 25 Years · Female only
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
3
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 9, 2022 · Synced May 22, 2026, 1:18 AM EDT
Recruiting No phase listed Observational
View directory record Official record
Conditions
Gender Dysphoria, Adult
Interventions
Tubularized augmented peritoneal cap vaginoplasty, Biopsy
Procedure
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
19 Years to 99 Years · Male only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 15, 2025 · Synced May 22, 2026, 1:18 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Gender Dysphoria, Mastectomy, Hypertrophic Scar
Interventions
Brijjit® BP100-6 and BP-75, Control: Standard of care and normal wound dressing
Device · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
19 Years and older
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced May 22, 2026, 1:18 AM EDT
Recruiting No phase listed Observational
View directory record Official record
Conditions
Gender Identity, Gender Dysphoria in Adolescents and Adults, Headache, Transgender
Interventions
Testosterone
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
12 Years to 20 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 2, 2025 · Synced May 22, 2026, 1:18 AM EDT
Enrolling by invitation Phase 2Phase 3 Interventional
View directory record Official record
Conditions
Gender Dysphoria
Interventions
Polyethylene Glycol 3350
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 19, 2025 · Synced May 22, 2026, 1:18 AM EDT
Completed No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Sleep Disorder, Insulin Resistance, Gender Dysphoria
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
12 Years to 18 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 15, 2025 · Synced May 22, 2026, 1:18 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Gender Dysphoria in Adolescents and Adults
Interventions
Pre- and Post-Surgical Transgender Therapeutic Support Group
Behavioral
Lead sponsor
Denver Health and Hospital Authority
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 4, 2022 · Synced May 22, 2026, 1:18 AM EDT
Active, not recruiting No phase listed Observational
View directory record Official record
Conditions
Gender Dysphoria, Transgender
Interventions
Oophorectomy, Infectious Disease Testing
Procedure · Diagnostic Test
Lead sponsor
University of Pittsburgh
Other
Eligibility
9 Years and older · Female only
Enrollment
20 participants
Timeline
2020 – 2030
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced May 22, 2026, 1:18 AM EDT
Active, not recruiting No phase listed Observational
View directory record Official record
Conditions
Gender Dysphoria, Transgender
Interventions
Infectious Disease Testing, Gonadal Tissue Removal
Diagnostic Test · Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
9 Years and older · Male only
Enrollment
150 participants
Timeline
2019 – 2029
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced May 22, 2026, 1:18 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Gender Dysphoria in Children, Puberty, Bone Development
Interventions
GnRH Agonist
Device
Lead sponsor
Amy DiVasta, MD
Other
Eligibility
9 Years to 14 Years
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
2
States / cities
Boston, Massachusetts • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced May 22, 2026, 1:18 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Hypogonadism, Gender Identity Dysphoria
Interventions
Fortesta, Estradiol
Drug
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 28, 2025 · Synced May 22, 2026, 1:18 AM EDT
Terminated Not applicable Interventional
View directory record Official record
Conditions
Transgender Women, Voice Alteration
Interventions
Visual-acoustic biofeedback: experimental
Behavioral
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older · Male only
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 23, 2025 · Synced May 22, 2026, 1:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Gender Dysphoria
Interventions
Trans Care Web App
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
138 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced May 22, 2026, 1:18 AM EDT
Recruiting Phase 3 Interventional
View directory record Official record
Conditions
Gender Dysphoria
Interventions
Ultrasound guided Continuous Infraclavicular Brachial Plexus Block, Ultrasound guided Continuous Femoral Nerve Block, Ultrasound guided Pudendal Nerve Block, Bupivacaine, Bilateral ultrasound guided Transversus Abdominis Plane Block, Bilateral spermatic cord block, Pecs I & II Block, Local anesthetic
Other · Drug
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
640 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced May 22, 2026, 1:18 AM EDT
Completed Phase 4 Interventional Results available
View directory record Official record
Conditions
Gender Dysphoria, Opioid Use, Pain, Postoperative
Interventions
Ropivacaine 0.2% Injectable Solution, Saline (0.9%)
Drug · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 2, 2023 · Synced May 22, 2026, 1:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Gender Dysphoria
Interventions
Trans Care Web App
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
312 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 21, 2025 · Synced May 22, 2026, 1:18 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Gender Dysphoria, Adolescent
Interventions
Depo-subQ Provera Injectable Product
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
15 Years to 21 Years · Female only
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced May 22, 2026, 1:18 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available
View directory record Official record
Conditions
Gender Dysphoria
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
986 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Bedford, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced May 22, 2026, 1:18 AM EDT