- Conditions
- Perimenopausal Depression, Depression
- Interventions
- Raloxifene, Rimostil, Transdermal Estradiol, Placebo skin patch and placebo tablets
- Drug
- Lead sponsor
- National Institute of Mental Health (NIMH)
- NIH
- Eligibility
- 40 Years to 60 Years · Female only
- Enrollment
- 65 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2002 – 2015
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 4, 2016 · Synced May 22, 2026, 4:14 AM EDT