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ClinicalTrials.gov public records Last synced May 21, 2026, 5:58 PM EDT

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Filters: Condition: Grade 3 Isocitrate Dehydrogenase (IDH) Wildtype Astrocytoma Clear all

Terminated Phase 1 Interventional

Study of Icapamespib (PU-AD) in Patients With Recurrent Malignant Glioma

NCT04782609

View directory record Official record

Conditions: Recurrent Glioblastoma Multiforme (GBM), Grade 3 Isocitrate Dehydrogenase (IDH) Wildtype Astrocytoma, Grade 3 or 4 Astrocytoma, Glioblastoma Surgery
Interventions: Icapamespib; Drug
Lead sponsor: Samus Therapeutics, Inc.; Industry
Eligibility: 18 Years and older

Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 5
States / cities: Los Angeles, California • San Diego, California • New York, New York + 2 more

Source: ClinicalTrials.gov public record

Updated Nov 16, 2022 · Synced May 21, 2026, 5:58 PM EDT

Recruiting Phase 1Phase 2 Interventional

A Study of Debio 0123 in Combination With Temozolomide in Adult Participants With Recurrent or Progressive Glioblastoma and of Debio 0123 in Combination With Temozolomide and Radiotherapy in Adult Participants With Newly Diagnosed Glioblastoma

NCT05765812

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Conditions: Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype, Astrocytoma, Grade III
Interventions: Debio 0123, Temozolomide, Radiotherapy; Drug · Radiation
Lead sponsor: Debiopharm International SA; Industry
Eligibility: 18 Years and older

Enrollment: 116 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 8
States / cities: Chicago, Illinois • New York, New York • Dallas, Texas + 4 more

Source: ClinicalTrials.gov public record

Updated Apr 27, 2026 · Synced May 21, 2026, 5:58 PM EDT