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Showing 1–24 of 75 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Gulf War Illness Clear all
Completed Phase 2 Interventional Results available

Gulf War Illness Nasal Irrigation Study

NCT01700725
View directory record Official record
Conditions
Persian Gulf Syndrome, Chronic Sinusitis, Fatigue, Acute Sinusitis
Interventions
Nasal Irrigation - Saline, Nasal Irrigation - Xylitol
Other · Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
35 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 20, 2019 · Synced Jul 21, 2026, 10:23 PM EDT
Recruiting Phase 3 Interventional

Coenzyme Q10 for Gulf War Illness: A Replication Study

NCT06515184
View directory record Official record
Conditions
Gulf War Syndrome, Persian Gulf Syndrome, Mitochondrial Disorder, Respiratory Chain
Interventions
PharmaNord Bio-Quinone Active CoQ10 Gold 100mg, PharmaNord Placebo
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
50 Years and older
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Jul 21, 2026, 10:23 PM EDT
Terminated Early Phase 1 Interventional

Ketamine in Veterans With Gulf War Illness

NCT04712071
View directory record Official record
Conditions
Gulf War Syndrome
Interventions
Ketamine Hydrochloride
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 2, 2022 · Synced Jul 21, 2026, 10:23 PM EDT
Not listed Phase 1 Interventional

Understanding GWI: Integrative Modeling

NCT04255498
View directory record Official record
Conditions
Gulf War Illness, Persian Gulf Syndrome, Occupational Diseases
Interventions
Etanercept, Mifepristone
Drug
Lead sponsor
South Florida Veterans Affairs Foundation for Research and Education
Federal
Eligibility
40 Years to 70 Years · Male only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Feb 4, 2020 · Synced Jul 21, 2026, 10:23 PM EDT
Completed Not applicable Interventional Results available

Treating Chronic Pain in Gulf War Illness

NCT02378025
View directory record Official record
Conditions
Chronic Pain, Gulf War Illness, Chronic Illness
Interventions
Yoga Group, Pain Management Wellness Group
Behavioral
Lead sponsor
Palo Alto Veterans Institute for Research
Other
Eligibility
42 Years to 85 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jun 10, 2020 · Synced Jul 21, 2026, 10:23 PM EDT
Completed Phase 2 Interventional

Clinical Benefits of a Novel Sleep-focused Mind-body Program on Gulf War Illness (GWI) Symptoms

NCT01543997
View directory record Official record
Conditions
Sleep Disturbance, Persian Gulf War Syndrome in Veteran
Interventions
Mind-Body Bridging Program, Supportive Education
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
38 Years to 80 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
2
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 17, 2016 · Synced Jul 21, 2026, 10:23 PM EDT
Recruiting Not applicable Interventional

Cranial Electrotherapy Stimulation and Brain Imaging for Gulf War Syndrome

NCT07151248
View directory record Official record
Conditions
Gulf War Syndrome
Interventions
Cranial electrical/electrotherapy stimulation (CES), Sham Cranial electrical/electrotherapy stimulation (CES)
Device
Lead sponsor
Emory University
Other
Eligibility
40 Years to 80 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Jul 21, 2026, 10:23 PM EDT
Recruiting Phase 3 Interventional

Confirmation of Diet as a Treatment for Gulf War Illness

NCT05675878
View directory record Official record
Conditions
Gulf War Syndrome, Gulf War Illness
Interventions
Dietary Intervention
Behavioral
Lead sponsor
American University
Other
Eligibility
50 Years to 75 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
3
States / cities
Washington D.C., District of Columbia • Fort Lauderdale, Florida • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 8, 2024 · Synced Jul 21, 2026, 10:23 PM EDT
Recruiting Phase 2 Interventional

Resistant Potato Starch to Alleviate GWI

NCT05820893
View directory record Official record
Conditions
Gulf War Illness
Interventions
Resistant Potato Starch
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years to 85 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Jul 21, 2026, 10:23 PM EDT
Completed Phase 2 Interventional Results available

Gulf War Illness Inflammation Reduction Trial

NCT02506192
View directory record Official record
Conditions
Chronic Inflammation, Chronic Pain, Fatigue, Cognitive Impairment
Interventions
Modified-Release Prednisone, Placebo
Drug
Lead sponsor
Minneapolis Veterans Affairs Medical Center
Federal
Eligibility
Not listed
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2023
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 9, 2024 · Synced Jul 21, 2026, 10:23 PM EDT
Recruiting Not applicable Interventional

Confirming the Effects of Acupuncture Treatments to Relieve Symptoms of Gulf War Illness

NCT06716411
View directory record Official record
Conditions
Persian Gulf Syndrome, Gulf War Syndrome, Multiple Chronic Illnesses, Occupational Diseases, War-Related Injuries, Wounds and Injuries
Interventions
Acupuncture
Device
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
10
States / cities
Berkeley, California • Los Angeles, California • Colorado Springs, Colorado + 7 more
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced Jul 21, 2026, 10:23 PM EDT
Not listed Phase 1Phase 2 Interventional

Thermal Clinic Treatment in Gulf War Illness

NCT02293291
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Lithium Water
Dietary Supplement
Lead sponsor
American Society Of Thermalism And Climatology Inc
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 22, 2015 · Synced Jul 21, 2026, 10:23 PM EDT
Recruiting Early Phase 1 Interventional

GWICTIC: NAC Mechanistic Study in Gulf War Veterans

NCT04987775
View directory record Official record
Conditions
Gulf War Syndrome
Interventions
N-Acetyl Cysteine, Placebo
Drug
Lead sponsor
Nova Southeastern University
Other
Eligibility
47 Years to 70 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
7
States / cities
Palo Alto, California • Fort Lauderdale, Florida • Boston, Massachusetts + 4 more
Source: ClinicalTrials.gov public record
Updated Jul 7, 2025 · Synced Jul 21, 2026, 10:23 PM EDT
Completed Not applicable Interventional Results available

Groups for Regaining Our Wellbeing

NCT03058952
View directory record Official record
Conditions
Gulf War, Fatigue, Pain, Depression
Interventions
Mindfulness-Based Stress Reduction, Chronic Disease Self-Management Program
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
245 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 20, 2024 · Synced Jul 21, 2026, 10:23 PM EDT
Completed Not applicable Interventional

rTMS in Alleviating Pain and Co-Morbid Symptoms in Gulf War Veterans Illness (GWVI)

NCT04046536
View directory record Official record
Conditions
Gulf War Illness, Depression
Interventions
Transcranial Magnetic Stimulation, Sham Transcranial Magnetic Stimulation
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
3
States / cities
Palo Alto, California • San Diego, California • Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Jul 21, 2026, 10:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Alleviating Headache and Pain in GWI With Neuronavigation Guided rTMS

NCT03030794
View directory record Official record
Conditions
Gulf War Syndrome, Headache
Interventions
Repetitive transcranial magnetic stimulation, Repetitive transcranial magnetic stimulation (sham)
Device
Lead sponsor
Veterans Medical Research Foundation
Other
Eligibility
18 Years to 65 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
2
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jan 17, 2020 · Synced Jul 21, 2026, 10:23 PM EDT
Recruiting Not applicable Interventional

Nicotinamide Riboside Clinical Trial for GWI

NCT05243290
View directory record Official record
Conditions
Gulf War Illness
Interventions
Nicotinamide Riboside, Placebo
Dietary Supplement
Lead sponsor
Roskamp Institute Inc.
Other
Eligibility
47 Years to 70 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Fort Lauderdale, Florida • Sarasota, Florida
Source: ClinicalTrials.gov public record
Updated Jul 23, 2025 · Synced Jul 21, 2026, 10:23 PM EDT
Completed Phase 2 Interventional Results available

Complementary Neurosteroid Intervention in Gulf War Illnesses (GWVI)

NCT01956279
View directory record Official record
Conditions
Fatigue, Musculoskeletal Pain, Cognitive Decline
Interventions
Pregnenolone, Placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years to 65 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 30, 2020 · Synced Jul 21, 2026, 10:23 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

NIH Investigative Deep Phenotyping Study of Gulf War Veteran Health (Project NIH IN-DEPTH)

NCT05375812
View directory record Official record
Conditions
Gulf War Illness
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
48 Years to 70 Years
Enrollment
85 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2030
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Jul 21, 2026, 10:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

OEA for Targeting Lipid Metabolism in GWI

NCT05252949
View directory record Official record
Conditions
Gulf War Illness
Interventions
Oleoylethanolamide (OEA), Placebo
Dietary Supplement
Lead sponsor
Roskamp Institute Inc.
Other
Eligibility
Up to 70 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Sarasota, Florida
Source: ClinicalTrials.gov public record
Updated Aug 7, 2025 · Synced Jul 21, 2026, 10:23 PM EDT
Recruiting Phase 2 Interventional

Growth Hormone Replacement in Veterans With GWI and AGHD (GWIT)

NCT05355272
View directory record Official record
Conditions
Gulf War Syndrome, Adult Growth Hormone Deficiency
Interventions
Recombinant human growth hormone
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 64 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Houston, Texas • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Jul 21, 2026, 10:23 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Study of Gulf War Illness (GWI) by Comparing GWI and Healthy Veterans

NCT00810225
View directory record Official record
Conditions
Gulf War Illness, Persian Gulf War Syndrome
Interventions
Not listed
Lead sponsor
Georgetown University
Other
Eligibility
Not listed
Enrollment
516 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jun 17, 2018 · Synced Jul 21, 2026, 10:23 PM EDT
Completed Not applicable Interventional

Curcumin, Resveratrol, and Stinging Nettle as Treatments for GWI

NCT05377242
View directory record Official record
Conditions
Gulf War Illness
Interventions
Curcumin, Resveratrol, Stinging Nettle
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
45 Years and older
Enrollment
390 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Jul 21, 2026, 10:23 PM EDT
Completed Not applicable Interventional

Treatment of Memory Disorders in Gulf War Illness With High Definition Transcranial Direct Cortical Stimulation

NCT03542383
View directory record Official record
Conditions
Memory Disorders, Word Finding Difficulty
Interventions
High Definition Transcranial Direct Current Stimulation, Sham High Definition Transcranial Direct Current Stimulation
Device
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
45 Years to 78 Years
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Jul 21, 2026, 10:23 PM EDT