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ClinicalTrials.gov public records Last synced Oct 21, 2026, 12:12 AM EDT

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Showing 1–24 of 464 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: HIV Risk Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Y2Prevent: Preventing Drug Use and HIV Through Empowerment, Social Support and Mentorship (Y2P)

NCT04504981
View directory record Official record
Conditions
HIV, Drug Use
Interventions
Y2Prevent
Behavioral
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
18 Years to 24 Years · Male only
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 18, 2023 · Synced Oct 21, 2026, 12:12 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Development and Evaluation of a Virtual Reality Tool for At-Risk Trauma-Exposed Young People

NCT05816083
View directory record Official record
Conditions
Substance Use Disorders, HIV Infections
Interventions
Virtual Reality Tool
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
15 Years to 30 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 21, 2026, 12:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Young Men's Health Project Targeting HIV Risk Reduction and Substance Abuse

NCT03577301
View directory record Official record
Conditions
HIV Infections
Interventions
Clinic-based Delivery, Remote Delivery, Multi-modal Delivery
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
15 Years to 24 Years · Male only
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
3
States / cities
Miami, Florida • Detroit, Michigan • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 3, 2024 · Synced Oct 21, 2026, 12:12 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Safety and Pharmacokinetic Study of Oral MK-8527 QM in Participants at Low-Risk for HIV-1 Infection (MK-8527-007)

NCT06045507
View directory record Official record
Conditions
HIV, HIV Pre-exposure Prophylaxis
Interventions
MK-8527, Placebo to MK-8527
Drug
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Eligibility
18 Years to 65 Years
Enrollment
352 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
10
States / cities
North Hollywood, California • San Francisco, California • Hallandale, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Oct 21, 2026, 12:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Acceptability, Feasibility, and Preliminary Impact of a Web-based, HIV Prevention Toolkit With Cisgender Male Couples in Lima, Peru

NCT05873855
View directory record Official record
Conditions
HIV Infections, Hiv, Sexually Transmitted Infections (Not HIV or Hepatitis), Sexually Transmitted Diseases, Sexual Behavior, Risk Reduction
Interventions
Para ti, para mi, para nosotros (P3), Waitlist Control Para ti, para mi, para nosotros (P3)
Behavioral
Lead sponsor
Florida International University
Other
Eligibility
18 Years and older · Male only
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jul 28, 2025 · Synced Oct 21, 2026, 12:12 AM EDT
Recruiting Phase 2 Interventional

GLP-1 Receptor Agonists to Decrease Ethanol and CVD Risk in HIV

NCT07221214
View directory record Official record
Conditions
HIV, Alcohol, Smoking Cigarette, Cardiovascular Disease Prevention
Interventions
Semaglutide (Rybelsus®), Placebo
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 89 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Oct 21, 2026, 12:12 AM EDT
Completed Phase 3 Interventional

A Study of Acyclovir to Help Prevent HIV Infection in People With Genital Herpes

NCT00076232
View directory record Official record
Conditions
HIV Infections, HIV Seronegativity, Herpes Genitalis
Interventions
Acyclovir, Acyclovir placebo
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
Not listed
Enrollment
3,682 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
3
States / cities
San Francisco, California • New York, New York • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 30, 2010 · Synced Oct 21, 2026, 12:12 AM EDT
Completed Not applicable Interventional

Healthy Choices to Promote Health and Reduce Risk in HIV-Infected Youth

NCT00103532
View directory record Official record
Conditions
HIV Infection
Interventions
Healthy Choices - Motivational Enhancement Intervention, Standard care
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
16 Years to 24 Years
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
6
States / cities
Los Angeles, California • Fort Lauderdale, Florida • Baltimore, Maryland + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 26, 2019 · Synced Oct 21, 2026, 12:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Adapting and Evaluating an EBI to Prevent HIV/AIDS Risk Among Apache Youth

NCT01910714
View directory record Official record
Conditions
HIV/AIDS
Interventions
Focus On Youth, Health Education Control Condition
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
13 Years to 19 Years
Enrollment
267 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 16, 2015 · Synced Oct 21, 2026, 12:12 AM EDT
Completed Phase 3 Interventional

Behavioral Drug and HIV Risk Reduction Counseling in Methadone Patients in China

NCT00757744
View directory record Official record
Conditions
Opiate Dependence, HIV Infections
Interventions
Behavioral Drug and HIV Risk Reduction Counseling (BDRC), Drug counseling
Behavioral
Lead sponsor
Yale University
Other
Eligibility
20 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 30, 2020 · Synced Oct 21, 2026, 12:12 AM EDT
Completed Early Phase 1 Interventional Results available

Zinc Effect on Inflammation and Cardiovascular Risk in HIV

NCT05085834
View directory record Official record
Conditions
Inflammation, Cardiovascular Diseases, Zinc Deficiency
Interventions
Zinc Gluconate, Placebo
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Oct 21, 2026, 12:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Increasing PrEP Among African Americans in Louisville KY

NCT03559595
View directory record Official record
Conditions
HIV/AIDS PREVENTION
Interventions
Project Prevent
Behavioral
Lead sponsor
University of Louisville
Other
Eligibility
18 Years to 29 Years
Enrollment
205 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 29, 2021 · Synced Oct 21, 2026, 12:12 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Behavioral Activation and Risk Reduction for Stimulant Use Among Sexually Active Adolescents and Young Adults

NCT06444360
View directory record Official record
Conditions
HIV
Interventions
IMPACT, eSOC
Behavioral
Lead sponsor
Westat
Other
Eligibility
16 Years to 24 Years
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
2
States / cities
Los Angeles, California • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Oct 21, 2026, 12:12 AM EDT
Completed Phase 2 Interventional

Urban Health Study II

NCT01402466
View directory record Official record
Conditions
HIV
Interventions
Standard Referral, Project Bridge
Behavioral
Lead sponsor
RTI International
Other
Eligibility
18 Years to 70 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 28, 2016 · Synced Oct 21, 2026, 12:12 AM EDT
Completed No phase listed Observational

Neurobehavioral Model of HIV in Injection Drug Users

NCT00198861
View directory record Official record
Conditions
Drug Abuse, HIV Infections
Interventions
Injection and Non-Injection Drug Users
Other
Lead sponsor
The City College of New York
Other
Eligibility
15 Years to 50 Years
Enrollment
836 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2016
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 2, 2016 · Synced Oct 21, 2026, 12:12 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Project Power: An HIV Risk Reduction Intervention for Black Men Who Have Sex With Men and Women (BMSM/W)

NCT01376895
View directory record Official record
Conditions
Unsafe Sex, Risk Reduction
Interventions
PROJECT POWER, Power Health
Behavioral
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years to 60 Years · Male only
Enrollment
211 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 11, 2014 · Synced Oct 21, 2026, 12:12 AM EDT
Completed Not applicable Interventional

A Structural HIV Prevention Intervention Targeting High-risk Women

NCT04413591
View directory record Official record
Conditions
Sex Work
Interventions
Community based combination HIV prevention package
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years and older · Female only
Enrollment
385 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 5, 2022 · Synced Oct 21, 2026, 12:12 AM EDT
Withdrawn Phase 2 Interventional

HIV Risk Reduction and Drug Abuse Treatment in Iran

NCT00398008
View directory record Official record
Conditions
Opiate Dependence, HIV Infections
Interventions
Buprenorphine/Subutex, Naltrexone, Drug counseling
Drug · Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 30, 2020 · Synced Oct 21, 2026, 12:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

PC4PrEP: Integrating PrEP Into Primary Care

NCT03617874
View directory record Official record
Conditions
Human Immunodeficiency Virus Transmission
Interventions
PC4PrEP- Intervention Clinics, Standard of Care Clinics
Other
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Sep 16, 2022 · Synced Oct 21, 2026, 12:12 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluating an Interactive Digital Toolkit for Women's PrEP Implementation

NCT07292584
View directory record Official record
Conditions
HIV Prevention, HIV Risk, Sexual and Reproductive Health
Interventions
Interactive Digital PrEP Toolkit
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older · Female only
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
4
States / cities
Birmingham, Alabama • Montgomery, Alabama • Tuscaloosa, Alabama + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Oct 21, 2026, 12:12 AM EDT
Not listed Phase 1Phase 2 Interventional Accepts healthy volunteers

Evaluation of Re-Entry Values and Mindfulness Program (REVAMP) With Jail Inmates

NCT01378923
View directory record Official record
Conditions
Impulsive Behavior, Substance Abuse, HIV Risk Behavior, Anxiety, Depression, Criminogenic Thinking
Interventions
REVAMP, TAU
Behavioral
Lead sponsor
George Mason University
Other
Eligibility
18 Years and older · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated May 7, 2013 · Synced Oct 21, 2026, 12:12 AM EDT
Completed Phase 3 Interventional Results available

Evaluating the Use of Pitavastatin to Reduce the Risk of Cardiovascular Disease in HIV-Infected Adults

NCT02344290
View directory record Official record
Conditions
HIV, Cardiovascular Diseases
Interventions
Pitavastatin, Placebo
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
40 Years to 75 Years
Enrollment
7,769 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2023
U.S. locations
91
States / cities
Birmingham, Alabama • Tucson, Arizona • Los Angeles, California + 59 more
Source: ClinicalTrials.gov public record
Updated Sep 4, 2025 · Synced Oct 21, 2026, 12:12 AM EDT
Completed Not applicable Interventional

Juvenile Justice Girls Randomized Control Trial: Young Adult Follow-up

NCT01341626
View directory record Official record
Conditions
Delinquency, Drug Use
Interventions
Treatment Foster Care (TFCO), Group Care
Behavioral
Lead sponsor
Oregon Social Learning Center
Other
Eligibility
13 Years to 18 Years · Female only
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2016
U.S. locations
2
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 11, 2022 · Synced Oct 21, 2026, 12:12 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Project EMPOWERING: Evidence-based PrEP for Justice-Involved Women and Their Risk Networks

NCT03293290
View directory record Official record
Conditions
HIV Infections
Interventions
PrEP
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Female only
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 28, 2021 · Synced Oct 21, 2026, 12:12 AM EDT