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Showing 1–24 of 1,105 matching trials from the live ClinicalTrials.gov search.
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Completed Early Phase 1 Interventional Accepts healthy volunteers

Smoking Cessation for Young Adults Who Binge Drink - 1

NCT00218452
Conditions
Adherence, Tobacco Use Cessation, Alcohol & Drug Use, Nicotine Transdermal System
Interventions
Lifestyle counseling
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 25 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
3
States / cities
Jacksonville, Florida • Rochester, Minnesota
Conditions
Family Planning Services, Substance-Related Disorders, Opiate Substitution Treatment, Sexual Health
Interventions
Sexual Health Initiative for Navigation and Education (SHINE) Health Educator Intervention
Behavioral
Lead sponsor
Denver Health and Hospital Authority
Other
Eligibility
18 Years to 44 Years
Enrollment
199 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Denver, Colorado
Conditions
Binge Alcohol Consumption, Suicidal Ideation
Interventions
EA-Avatar, Suicide safety planning app
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years to 29 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Marlborough, Massachusetts • Worcester, Massachusetts
Conditions
Substance Dependence, Compliance, Treatment Outcome
Interventions
Contracting, Prompting and Reinforcing
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
Not listed
Enrollment
157 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2005
U.S. locations
1
States / cities
Salem, Virginia
Completed Not applicable Interventional Results available

Treatment of Prolonged Grief Disorder in Combat Veterans

NCT02283333
Conditions
Prolonged Grief Disorder
Interventions
BATE-G, Standard Treatment
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years and older
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
2
States / cities
Charleston, South Carolina
Conditions
Alcohol Use Disorder, Risk Behavior, Health, Dysbiosis, HIV Infections
Interventions
Screening, Brief Intervention, Referral to Treatment (SBIRT)
Behavioral
Lead sponsor
Shirish S Barve
Other
Eligibility
18 Years to 85 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Louisville, Kentucky
Completed No phase listed Observational Accepts healthy volunteers

Patient Reported Outcomes for Opioid Use Disorder

NCT03985163
Conditions
Opioid-use Disorder, Overdose of Opiate, Patient Participation
Interventions
Patient Reported Outcomes Electronic Survey
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
New Haven, Connecticut
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The STop UNhealthy Substance Use Now Trial

NCT06524232
Conditions
Risky Health Behavior, Substance Use Disorders, Substance Abuse, Alcohol Use Disorder, Drinking, Alcohol, Substance Use
Interventions
Practice Facilitation (PF), Learning Collaborative (LC), Performance Incentives (PI)
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
3
States / cities
Cincinnati, Ohio • Columbus, Ohio
Completed Not applicable Interventional Accepts healthy volunteers

The Pitt Center for Emergency Responder Wellness

NCT05357586
Conditions
Posttraumatic Stress Disorder, Depression, Anxiety, Alcohol Use Disorder
Interventions
Unified Protocol for Transdiagnostic Treatment of Emotional Disorders
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers

Developing a Digital Intervention to Prevent Risky Health Behaviors

NCT06538922
Conditions
Substance Use
Interventions
Single Session Family Intervention
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
12 Years to 14 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Burlington, Vermont
Conditions
Sexual Satisfaction, Sexual Function
Interventions
Spark Placebo Control Form 1, Spark Active Study Product 1.1 Usage, Spark Placebo Control Form 2, Spark Active Study Product 2.1 Usage
Dietary Supplement
Lead sponsor
Radicle Science
Industry
Eligibility
21 Years to 105 Years · Male only
Enrollment
1,202 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Del Mar, California
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Intermittent Fasting on Brain Health

NCT06019195
Conditions
Intermittent Fasting, Aging
Interventions
Time restricted eating
Other
Lead sponsor
University of Oklahoma
Other
Eligibility
55 Years to 80 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Conditions
Breast Cancer
Interventions
Intermittent Fasting
Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Not listed Not applicable Interventional Accepts healthy volunteers

Prosocial Behavior and Exercise Among Older Adults

NCT00747019
Conditions
Health-Related Quality of Life, Physical Activity, Physical Function
Interventions
Prosocial Behavior Physical Activity (PBPA), Physical Exercise (PE)
Behavioral
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
55 Years to 80 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pilot Testing a Mobile App to Designed to Increase Physical Activity Among Pregnant and Postpartum Women

NCT04480931
Conditions
Pregnancy, Postpartum
Interventions
mHealth Intervention Group, Educational Brochure
Behavioral
Lead sponsor
Western Kentucky University
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Bowling Green, Kentucky
Conditions
Depression, Anxiety, Post Traumatic Stress Disorder
Interventions
Intervention (videoconferencing)
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Opioid Use Disorder, Cigarette Smoking
Interventions
Telehealth Motivational Counseling, Nicotine Replacement Product, National Institute on Drug Abuse (NIDA) Standardized Research Electronic Cigarette (SREC).
Behavioral · Drug · Device
Lead sponsor
NYU Langone Health
Other
Eligibility
21 Years to 75 Years
Enrollment
302 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
New York, New York • The Bronx, New York
Conditions
Alcohol Drinking, Binge Drinking, Text Messaging
Interventions
Brief Alcohol Intervention, Automated and Targeted Text Messages
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
7,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
San Antonio, Texas
Conditions
Bipolar Disorder
Interventions
Nutrition, Exercise, and Wellness (NEW) psychotherapy, Typically consists of at least one FDA-approved mood stabilizer
Other · Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Pregnancy Related, Sexually Transmitted Diseases, Adolescent Behavior
Interventions
Yes and Know curriculum, Nutrition Education for Adolescents
Behavioral
Lead sponsor
ETR Associates
Other
Eligibility
14 Years to 19 Years
Enrollment
449 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Watsonville, California
Active, not recruiting Phase 3 Interventional

Optimizing Tobacco Use Treatment for PLWHA

NCT04176172
Conditions
HIV/AIDS, Nicotine Dependence
Interventions
Varenicline, Nicotine patch, Standard treatment, Standard treatment + Managed Problem Solving (MAPS) adherence intervention
Drug · Behavioral
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
340 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
2
States / cities
Chicago, Illinois • Philadelphia, Pennsylvania
Conditions
Opioid Use Disorder, Pregnancy
Interventions
Empowering Pregnant Women and People Receiving medications for opioid use disorder (EMPWR), Medication monitoring (control)
Behavioral · Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Tobacco, Posttraumatic Stress Disorder
Interventions
Acceptance and Commitment Therapy for PTSD and Tobacco Use, Freedom From Smoking
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Bedford, Massachusetts
Conditions
Mild Traumatic Brain Injury, Posttraumatic Stress Disorders, Depression
Interventions
Multifamily Group for mTBI for Couples, Group Health Education (GHE)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
249 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
3
States / cities
Baltimore, Maryland • New York, New York • The Bronx, New York