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ClinicalTrials.gov public records Last synced May 22, 2026, 1:02 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 286 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Heart Failure, Left-Sided Clear all
Withdrawn Phase 4 Interventional
View directory record Official record
Conditions
Hemolysis Intravascular, Acute Decompensated Heart Failure
Interventions
Pentoxifylline Oral Product, Placebo
Drug
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 30, 2025 · Synced May 22, 2026, 1:02 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Congestive Heart Failure, Ventricular Function, Left
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2015
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 22, 2016 · Synced May 22, 2026, 1:02 AM EDT
Withdrawn Phase 4 Interventional
View directory record Official record
Conditions
Hypertension
Interventions
Eplerenone, placebo
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
40 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
2
States / cities
St Louis, Missouri • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 2, 2015 · Synced May 22, 2026, 1:02 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Heart Failure, Left Bundle-Branch Block
Interventions
Mapping and Pacing the His Bundle, Placing a guidewire in Coronary sinus for measurement of Q-LV during His Bundle pacing or, if needed, for LV pacing
Procedure
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced May 22, 2026, 1:02 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Advanced Refractory Left Ventricular Heart Failure
Interventions
HeartMate 3 LVAS
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years to 100 Years
Enrollment
1,685 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
69
States / cities
Little Rock, Arkansas • Beverly Hills, California • La Jolla, California + 53 more
Source: ClinicalTrials.gov public record
Updated Jun 26, 2022 · Synced May 22, 2026, 1:02 AM EDT
Completed Phase 1 Interventional
View directory record Official record
Conditions
Left Ventricular Insufficiency
Interventions
CD-NP, Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 29, 2016 · Synced May 22, 2026, 1:02 AM EDT
Terminated Phase 3 Interventional Results available
View directory record Official record
Conditions
Heart Failure
Interventions
Iobenguane I -123 Injection, Implantable Cardioverter Defibrillator, Thyroid blocking
Drug · Device
Lead sponsor
GE Healthcare
Industry
Eligibility
18 Years and older
Enrollment
395 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
29
States / cities
Birmingham, Alabama • Bakersfield, California • La Mesa, California + 24 more
Source: ClinicalTrials.gov public record
Updated May 21, 2019 · Synced May 22, 2026, 1:02 AM EDT
Terminated Phase 4 Interventional Results available
View directory record Official record
Conditions
Pulmonary Hypertension, Heart Failure With Preserved Ejection Fraction
Interventions
Ambrisentan, Placebo
Drug · Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 18, 2020 · Synced May 22, 2026, 1:02 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Heart Failure
Interventions
Pacing Lead
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
197 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
19
States / cities
Pasadena, California • Sacramento, California • Atlantis, Florida + 16 more
Source: ClinicalTrials.gov public record
Updated Feb 17, 2019 · Synced May 22, 2026, 1:02 AM EDT
Completed Phase 3 Interventional Results available
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
carvedilol controlled release, carvedilol immediate release
Drug
Lead sponsor
CTI-1, LLC
Industry
Eligibility
18 Years and older
Enrollment
318 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
75
States / cities
Mobile, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 67 more
Source: ClinicalTrials.gov public record
Updated Mar 27, 2023 · Synced May 22, 2026, 1:02 AM EDT
Completed Phase 2Phase 3 Interventional
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
CONTAK RENEWAL 2/4/4HE CRT-D, EASYTRAK 2 Lead
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2004
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 24, 2007 · Synced May 22, 2026, 1:02 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Heart Failure
Interventions
HM II (HeartMate II LVAD), OMM (Optimal Medical Management)
Device · Drug
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years to 85 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
52
States / cities
Little Rock, Arkansas • Beverly Hills, California • Los Angeles, California + 41 more
Source: ClinicalTrials.gov public record
Updated Jun 23, 2022 · Synced May 22, 2026, 1:02 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Heart Failure
Interventions
Not listed
Lead sponsor
Medtronic
Industry
Eligibility
Not listed
Enrollment
1,900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
81
States / cities
Birmingham, Alabama • Anchorage, Alaska • Chandler, Arizona + 78 more
Source: ClinicalTrials.gov public record
Updated Jan 31, 2022 · Synced May 22, 2026, 1:02 AM EDT
Withdrawn Not applicable Interventional
View directory record Official record
Conditions
Heart Failure
Interventions
Strength Training for Frailty
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 25, 2018 · Synced May 22, 2026, 1:02 AM EDT
Terminated Not applicable Interventional Results available
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
Medtronic 4195 active fixation LV lead and Medtronic passive fixation LV lead
Device
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Plano, Texas
Source: ClinicalTrials.gov public record
Updated May 25, 2014 · Synced May 22, 2026, 1:02 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
CT angiography
Procedure
Lead sponsor
VA Connecticut Healthcare System
Federal
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 26, 2009 · Synced May 22, 2026, 1:02 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Heart Failure
Interventions
No intervention is used. Collection of signals only.
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
2
States / cities
Richmond, Virginia • Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Jun 27, 2022 · Synced May 22, 2026, 1:02 AM EDT
Not listed Phase 3 Interventional
View directory record Official record
Conditions
End-stage Heart Failure, Cardiomyopathies
Interventions
VentrAssistTM Left Ventricular Assist Device
Device
Lead sponsor
Ventracor
Industry
Eligibility
18 Years and older
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
27
States / cities
Birmingham, Alabama • Phoenix, Arizona • Gainesville, Florida + 22 more
Source: ClinicalTrials.gov public record
Updated Sep 8, 2009 · Synced May 22, 2026, 1:02 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Heart Failure, Heart Assist Device, Hyponatremic
Interventions
tolvaptan
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 6, 2022 · Synced May 22, 2026, 1:02 AM EDT
Completed Phase 3 Interventional Results available
View directory record Official record
Conditions
Heart Failure
Interventions
sacubitril/valsartan
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
1 Year to 18 Years
Enrollment
216 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
15
States / cities
Loma Linda, California • Los Angeles, California • Palo Alto, California + 12 more
Source: ClinicalTrials.gov public record
Updated May 15, 2025 · Synced May 22, 2026, 1:02 AM EDT
Recruiting No phase listed Observational
View directory record Official record
Conditions
Hypertension, Pulmonary, Heart Failure With Reduced Ejection Fraction
Interventions
Eko CORE 500 Digital Stethoscope
Device
Lead sponsor
Eko Devices, Inc.
Industry
Eligibility
18 Years and older
Enrollment
3,850 participants
Timeline
2025 – 2026
U.S. locations
3
States / cities
O'Fallon, Illinois • Springfield, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 27, 2025 · Synced May 22, 2026, 1:02 AM EDT
Withdrawn Early Phase 1 Interventional
View directory record Official record
Conditions
Heart Failure
Interventions
EnSite NavX-Guided CRT implant
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Feb 3, 2019 · Synced May 22, 2026, 1:02 AM EDT
Completed Phase 4 Interventional Results available
View directory record Official record
Conditions
Heart Failure (HF), Ventricular Dysfunction, Left
Interventions
AdreView (Iobenguane I 123 Injection)
Drug
Lead sponsor
GE Healthcare
Industry
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Princeton, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 7, 2016 · Synced May 22, 2026, 1:02 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Heart Failure With Left Bundle Branch Block
Interventions
aCRT ON, aCRT OFF
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
3,797 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2022
U.S. locations
90
States / cities
Mesa, Arizona • Phoenix, Arizona • Little Rock, Arkansas + 76 more
Source: ClinicalTrials.gov public record
Updated Nov 28, 2023 · Synced May 22, 2026, 1:02 AM EDT