- Conditions
- Symptomatic Hypertrophic Cardiomyopathy (HCM)
- Interventions
- Aficamten (5 - 20 mg)
- Drug
- Lead sponsor
- Cytokinetics
- Industry
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 900 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2028
- U.S. locations
- 52
- States / cities
- Birmingham, Alabama • Anchorage, Alaska • Phoenix, Arizona + 39 more
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.
These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Showing 25–48
of 667
matching trials from the live ClinicalTrials.gov search.
- Conditions
- Hypertrophic Obstructive Cardiomyopathy, Thoracic Aortic Dilatation, Heart Disease Caused by Ionising Radiation, Quality of Life
- Interventions
- QOL Survey
- Other
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 380 participants
- Timeline
- 2019 – 2026
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Aortic Valve Stenosis
- Interventions
- V8 Balloon Aortic Valvuloplasty (BAV) Catheter
- Device
- Lead sponsor
- InterValve, Inc.
- Industry
- Eligibility
- Not listed
- Enrollment
- 103 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 7
- States / cities
- Los Angeles, California • Minneapolis, Minnesota • Nashville, Tennessee + 2 more
- Conditions
- Functional Tricuspid Regurgitation, Heart Valve Diseases, Tricuspid Valve Insufficiency
- Interventions
- Tricinch Coil System Implantation
- Device
- Lead sponsor
- 4Tech Cardio Ltd.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 7 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2020
- U.S. locations
- 9
- States / cities
- Los Angeles, California • Thousand Oaks, California • Atlanta, Georgia + 6 more
- Conditions
- Congenital Heart Disease, Tetrology of Fallot, RVOT Anomaly, Pulmonary Regurgitation
- Interventions
- Harmony TPV System
- Device
- Lead sponsor
- Medtronic Cardiovascular
- Industry
- Eligibility
- Not listed
- Enrollment
- 174 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2035
- U.S. locations
- 19
- States / cities
- Birmingham, Alabama • Los Angeles, California • Aurora, Colorado + 15 more
- Conditions
- Symptomatic Severe Aortic Stenosis
- Interventions
- TAVR Implantation with SAPIEN XT, SAVR Implantation
- Device
- Lead sponsor
- Edwards Lifesciences
- Industry
- Eligibility
- Not listed
- Enrollment
- 2,032 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2024
- U.S. locations
- 55
- States / cities
- Little Rock, Arkansas • La Jolla, California • Los Angeles, California + 46 more
- Conditions
- Cardiovascular Diseases, Heart Diseases, Atherosclerosis, HIV Infections, Cardiomyopathy, Hypertrophic
- Interventions
- Not listed
- Lead sponsor
- University of Miami
- Other
- Eligibility
- Up to 2 Years
- Enrollment
- 167 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2002 – 2006
- U.S. locations
- 5
- States / cities
- Miami, Florida • Chicago, Illinois • Boston, Massachusetts + 2 more
- Conditions
- Myocardial Infarction, Angina, Unstable, Cardiomyopathy, Hypertrophic
- Interventions
- Not listed
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 144 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1999 – 2016
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Cardiomyopathy
- Interventions
- Not listed
- Lead sponsor
- Tenaya Therapeutics
- Industry
- Eligibility
- 0 Years to 18 Years
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2028
- U.S. locations
- 21
- States / cities
- Little Rock, Arkansas • Los Angeles, California • Sacramento, California + 17 more
- Conditions
- Heart Disease, Congenital, Pulmonary Valve Replacement
- Interventions
- Not listed
- Lead sponsor
- Emory University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005
- U.S. locations
- 2
- States / cities
- Atlanta, Georgia
- Conditions
- Aortic Stenosis, Inflammation, Thrombosis
- Interventions
- Clopidogrel, Ticagrelor
- Drug
- Lead sponsor
- University Hospitals Cleveland Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2019
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Aortic Stenosis
- Interventions
- Self-Centering Guide Catheter
- Device
- Lead sponsor
- Boston Scientific Corporation
- Industry
- Eligibility
- 18 Years to 110 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Williams Syndrome
- Interventions
- Vitamin D
- Drug
- Lead sponsor
- National Center for Research Resources (NCRR)
- NIH
- Eligibility
- 18 Years to 50 Years
- Healthy volunteers
- Accepts healthy volunteers
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina
- Conditions
- Tricuspid Valve Insufficiency
- Interventions
- Tricuspid Valve Repair System
- Device
- Lead sponsor
- Abbott Medical Devices
- Industry
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 98 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2024
- U.S. locations
- 4
- States / cities
- Los Angeles, California • Detroit, Michigan • Minneapolis, Minnesota + 1 more
- Conditions
- Williams Syndrome, Angelman Syndrome, Prader-Willi Syndrome, Shprintzen Syndrome, Smith-Magenis Syndrome, DiGeorge Syndrome, Chromosome Abnormalities
- Interventions
- Not listed
- Lead sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
- NIH
- Eligibility
- 0 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 1999
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Hypertrophic Cardiomyopathy
- Interventions
- Extended Cardiac Monitoring
- Device
- Lead sponsor
- Atlantic Health System
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 83 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 1
- States / cities
- Morristown, New Jersey
- Conditions
- Tricuspid Regurgitation (TR)
- Interventions
- Tricuspid Transcatheter Edge-to-Edge Repair (TEER)
- Device
- Lead sponsor
- Abbott Medical Devices
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 1,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2033
- U.S. locations
- 5
- States / cities
- Phoenix, Arizona • La Jolla, California • Chicago, Illinois + 2 more
- Conditions
- Tricuspid Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease
- Interventions
- Edwards PASCAL System, Optimal Medical Therapy
- Device · Drug
- Lead sponsor
- Edwards Lifesciences
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 1,270 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2031
- U.S. locations
- 73
- States / cities
- Phoenix, Arizona • Tucson, Arizona • Irvine, California + 59 more
- Conditions
- Pulmonary Valve Insufficiency, Pulmonary Valve Stenosis, Heart Defects, Congenital, Congenital Abnormalities, Cardiovascular Diseases, Heart Diseases
- Interventions
- SAPIEN XT THV
- Device
- Lead sponsor
- Edwards Lifesciences
- Industry
- Eligibility
- Not listed
- Enrollment
- 57 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2025
- U.S. locations
- 12
- States / cities
- Birmingham, Alabama • Aurora, Colorado • Washington D.C., District of Columbia + 9 more
- Conditions
- Myocardial Infarction, Coronary Artery Bypass, Percutaneous Coronary Intervention, Heart Failure, Cardiac Valve Surgery
- Interventions
- RPE (usual care), GXT+THHR (intervention)
- Behavioral
- Lead sponsor
- Baystate Medical Center
- Other
- Eligibility
- 60 Years to 99 Years
- Enrollment
- 320 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 2
- States / cities
- Springfield, Massachusetts • Detroit, Michigan
- Conditions
- Coronary Artery Disease, Aortic Valve Stenosis, Tomography, X-Ray Computed
- Interventions
- Ultra-High Resolution Photon Counting Detector Coronary Computed Tomography Angiography
- Diagnostic Test
- Lead sponsor
- Semmelweis University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2030
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina
- Conditions
- Heart Valve Diseases
- Interventions
- ATS 3f Aortic Bioprosthesis
- Device
- Lead sponsor
- Medtronic Cardiovascular
- Industry
- Eligibility
- Up to 70 Years
- Enrollment
- 26 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2015
- U.S. locations
- 5
- States / cities
- Oak Lawn, Illinois • New York, New York • Philadelphia, Pennsylvania + 2 more
- Conditions
- Aortic Stenosis
- Interventions
- CoreValve Evolut R TAVR system
- Device
- Lead sponsor
- Medtronic Cardiovascular
- Industry
- Eligibility
- Not listed
- Enrollment
- 241 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2020
- U.S. locations
- 23
- States / cities
- Phoenix, Arizona • Los Angeles, California • New Haven, Connecticut + 18 more
- Conditions
- Tricuspid Regurgitation, Mechanical Ventilation Pressure High, Pediatric Respiratory Diseases
- Interventions
- Application of positive-end-expiratory pressure
- Other
- Lead sponsor
- Northwell Health
- Other
- Eligibility
- 3 Months to 18 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- New Hyde Park, New York