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ClinicalTrials.gov public records Last synced Oct 22, 2026, 4:23 PM EDT

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Showing 1–24 of 26 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Hemodynamic Instability Clear all
Completed No phase listed Observational Accepts healthy volunteers

Expert Consensus Statements for the Management of a Physiologically Difficult Airway Using the Delphi Method (PDADelphi)

NCT05762068
View directory record Official record
Conditions
Intubation; Difficult or Failed, Intubation Complication, Hemodynamic Instability, Critical Illness
Interventions
Delphi procedure
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 28, 2024 · Synced Oct 22, 2026, 4:23 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Individual Cerebral Hemodynamic Oxygenation Relationships (ICHOR 1)

NCT06195345
View directory record Official record
Conditions
HIE, TBI (Traumatic Brain Injury), TBI, Hemodynamic Instability, Hypoxic-Ischemic Encephalopathy
Interventions
MR Imaging
Diagnostic Test
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
1 Minute to 18 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2035
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 22, 2026, 4:23 PM EDT
Enrolling by invitation No phase listed Observational

Biventricular Remodeling in Transcatheter Tricuspid Valve Replacement - Acute Hemodynamic Instability Study

NCT06954792
View directory record Official record
Conditions
Tricuspid Regurgitation, Heart Failure, Structural Heart Disease, Interventional Cardiology
Interventions
Not listed
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Oct 22, 2026, 4:23 PM EDT
Completed No phase listed Observational

Non-Invasive Detection of Tissue Oxygen Deprivation in Premature Infants With Patent Ductus Arteriosus.

NCT03277768
View directory record Official record
Conditions
Premature Infant, Patent Ductus Arteriosus, Hemodynamic Instability
Interventions
Resonance Raman Spectroscopy (RRS)
Device
Lead sponsor
University of Florida
Other
Eligibility
Not listed
Enrollment
55 participants
Timeline
2015 – 2018
U.S. locations
2
States / cities
Gainesville, Florida • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 10, 2019 · Synced Oct 22, 2026, 4:23 PM EDT
Active, not recruiting Not applicable Interventional

A Rapid Diagnostic of Risk in Hospitalized Patients Using Machine Learning

NCT05893420
View directory record Official record
Conditions
Sepsis, Septicemia, Respiratory Failure, Hemodynamic Instability, COVID-19, Cardiac Arrest, Clinical Deterioration
Interventions
eCARTv5 clinical deterioration monitoring, Standard of care control
Device · Other
Lead sponsor
AgileMD, Inc.
Industry
Eligibility
18 Years and older
Enrollment
30,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
3
States / cities
New Haven, Connecticut • Clearwater, Florida • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 29, 2025 · Synced Oct 22, 2026, 4:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Measurement of Hemodynamic Responses to Lower Body Negative Pressure

NCT03582501
View directory record Official record
Conditions
Hypotension and Shock
Interventions
Lower body negative pressure
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 55 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
3
States / cities
Scottsdale, Arizona • Jacksonville, Florida • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 12, 2019 · Synced Oct 22, 2026, 4:23 PM EDT
Terminated Phase 3 Interventional

Trial Using Impella LP 2.5 System in Patients With Acute Myocardial Infarction Induced Hemodynamic Instability

NCT00972270
View directory record Official record
Conditions
Acute Myocardial Infarction
Interventions
Impella LP 2.5, Intra-Aortic Balloon Pump
Device
Lead sponsor
Abiomed Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
11
States / cities
Hartford, Connecticut • Chicago, Illinois • Shawnee Mission, Kansas + 7 more
Source: ClinicalTrials.gov public record
Updated Mar 21, 2011 · Synced Oct 22, 2026, 4:23 PM EDT
Not listed No phase listed Observational

Correlation of Hemodynamics Via Pulmonary Artery Catherization and the Cardiospire

NCT05003011
View directory record Official record
Conditions
Hemodynamic Instability
Interventions
Cardiospire
Device
Lead sponsor
Respirix, Inc.
Industry
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Aug 12, 2021 · Synced Oct 22, 2026, 4:23 PM EDT
Terminated Not applicable Interventional Results available

Hemodynamic Instability Index: The Impact to Care With a New Predictive Indicator

NCT02185521
View directory record Official record
Conditions
Shock, Hemodynamic Instability
Interventions
patient assessment
Other
Lead sponsor
Philips Healthcare
Industry
Eligibility
18 Years and older
Enrollment
127 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
2
States / cities
St Louis, Missouri • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 11, 2019 · Synced Oct 22, 2026, 4:23 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Physiological Validation of Current Machine Learning Models for Hemodynamic Instability in Humans

NCT03927066
View directory record Official record
Conditions
Hypotension and Shock
Interventions
Assigned Interventions
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 55 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 31, 2023 · Synced Oct 22, 2026, 4:23 PM EDT
Terminated Not applicable Interventional Results available

Hemodynamic Response During Goal Directed Fluid Therapy in the OR

NCT02365688
View directory record Official record
Conditions
Hemodynamic Instability
Interventions
Initial bolus pre-incision
Procedure
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 18, 2017 · Synced Oct 22, 2026, 4:23 PM EDT
Recruiting No phase listed Observational

Resuscitative TEE Collaborative Registry

NCT04972526
View directory record Official record
Conditions
Cardiac Arrest, Cardiac Arrest Circulatory, Cardiac Arrest, Out-Of-Hospital, Shock, Hemodynamic Instability
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 22, 2026, 4:23 PM EDT
Completed Phase 2Phase 3 Interventional

MAnnitol for Blood Pressure Stability in HemoDialysis (MAP-HD)

NCT04428372
View directory record Official record
Conditions
Hemodialysis Complication, Hemodynamic Instability
Interventions
Mannitol, 0.9% saline
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 24, 2025 · Synced Oct 22, 2026, 4:23 PM EDT
Completed No phase listed Observational

Intraoperative Angioembolization in the Management of Pelvic Fracture-Related Hemodynamic Instability

NCT00755365
View directory record Official record
Conditions
Pelvic Fractures and Associated Hemodynamic Instability
Interventions
Not listed
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 90 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2019
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 22, 2019 · Synced Oct 22, 2026, 4:23 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Development of an Algorithm for Prediction of Onset of Hemodynamic Instability in Humans

NCT00581204
View directory record Official record
Conditions
Hemorrhagic Shock
Interventions
Near-Infrared Diffuse Optical Spectroscopy
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 55 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Oct 20, 2022 · Synced Oct 22, 2026, 4:23 PM EDT
Recruiting No phase listed Observational

HemoSphere Alta Study

NCT07148323
View directory record Official record
Conditions
Hemodynamic Instability
Interventions
HemoSphere Alta Monitor, Swan-Ganz IQ pulmonary arterial catheter, ForeSight IQ Large sensor, and Acumen IQ sensor
Device
Lead sponsor
Becton, Dickinson and Company
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Oct 22, 2026, 4:23 PM EDT
Completed No phase listed Observational

Correlation Between Release of Cytokines From Liver Graft and Hemodynamic Instability

NCT01120743
View directory record Official record
Conditions
Liver Transplantation
Interventions
Not listed
Lead sponsor
Penn State University
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 24, 2017 · Synced Oct 22, 2026, 4:23 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Hemodynamics Monitoring During Lower Body Negative Pressure (LBNP) Induced Controlled Hypovolemia

NCT03592290
View directory record Official record
Conditions
Hypovolemia, Hemodynamic Instability
Interventions
Lower body negative pressure
Diagnostic Test
Lead sponsor
Yale University
Other
Eligibility
20 Years to 45 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2027
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Oct 22, 2026, 4:23 PM EDT
Not listed Phase 4 Interventional

Early Caffeine in Preterm Neonates

NCT03086473
View directory record Official record
Conditions
BPD - Bronchopulmonary Dysplasia, Apnea of Prematurity, Hemodynamic Instability, Intubation
Interventions
Caffeine Citrate, Placebo (Normal Saline)
Drug
Lead sponsor
Jennifer Shepherd
Other
Eligibility
Up to 1 Day
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 3, 2021 · Synced Oct 22, 2026, 4:23 PM EDT
Completed Not applicable Interventional Results available

A Pilot Trial of Continuous Portable Postoperative Hemodynamic And Saturation Monitoring On Hospital Wards

NCT04574908
View directory record Official record
Conditions
Hemodynamic Instability, Respiratory Complications of Care
Interventions
ViSi device
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
879 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 21, 2024 · Synced Oct 22, 2026, 4:23 PM EDT
Completed Not applicable Interventional Results available

Perioperative Multimodal General AnesTHesia Focusing on Specific CNS Targets in Patients Undergoing carDiac surgERies

NCT05279898
View directory record Official record
Conditions
Postoperative Delirium, Hemodynamic Instability, Pain, Neurocognitive Dysfunction
Interventions
EEG Monitoring, Ropivacaine, Ketamine, Remifentanil, Dexmedetomidine, Rocuronium, Propofol
Device · Drug
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
60 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 26, 2025 · Synced Oct 22, 2026, 4:23 PM EDT
Completed Not applicable Interventional

Efficacy of Ultrasound to Guide Management During a Rapid Response Event

NCT01838343
View directory record Official record
Conditions
Hemodynamic Instability, Respiratory Failure
Interventions
Ultrasound
Other
Lead sponsor
Beth Israel Medical Center
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 31, 2014 · Synced Oct 22, 2026, 4:23 PM EDT
Completed Not applicable Interventional

Lower Extremity Elevation to Minimize Hemodynamic Instability During Induction of General Anesthesia

NCT06513169
View directory record Official record
Conditions
Post Induction Hypotension
Interventions
Group 1: LEE
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 70 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Oct 22, 2026, 4:23 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Consortium for Optimized Integration of Bio-Artificial Blood Components for Adaptive Resuscitation Therapy

NCT05756426
View directory record Official record
Conditions
Hemorrhage, Hemodynamic Instability
Interventions
Prospective
Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 88 Years
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2029
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Oct 22, 2026, 4:23 PM EDT