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Showing 1–24 of 70 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Tranexamic Acid for Prevention of Hemorrhage in Cesarean Delivery

NCT03856164
Conditions
Post Partum Hemorrhage, Fibrinolysis; Hemorrhage, Blood Loss
Interventions
Tranexamic Acid, Placebo
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Dallas, Texas
Terminated No phase listed Observational Accepts healthy volunteers

CNAP vs IABP in Pregnant Women With Placenta Accreta

NCT04671680
Conditions
Placenta Accreta, Blood Pressure, Hemorrhage, Hemorrhage, Postpartum
Interventions
LiDCO CNAP Monitoring Equipment
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers Results available

Accuracy of Blood Loss Estimation After Vaginal Delivery

NCT00462839
Conditions
Postpartum Hemorrhage
Interventions
blood loss estimation
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 65 Years
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Von Willebrand Diseases
Interventions
Use of a postpartum diary and additional blood draws., VWF replacement therapy with Wilate, Tranexamic acid
Other · Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older · Female only
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
11
States / cities
Aurora, Colorado • New Haven, Connecticut • Miami, Florida + 8 more
Completed Phase 4 Interventional Results available

Prophylactic Methylergonovine for Twin Cesarean

NCT05772156
Conditions
Twin; Complicating Pregnancy, Postpartum Hemorrhage
Interventions
Methylergonovine, Placebo
Drug
Lead sponsor
Columbia University
Other
Eligibility
Up to 65 Years · Female only
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Adjunctive Misoprostol Treatment on Blood Loss at Vaginal Delivery

NCT02411916
Conditions
Postpartum Hemorrhage
Interventions
misoprostol
Biological
Lead sponsor
New York City Health and Hospitals Corporation
Other
Eligibility
18 Years and older · Female only
Enrollment
143 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2019
U.S. locations
1
States / cities
Jamaica, New York
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Prevention of Postpartum Hemorrhage With TXA

NCT03326596
Conditions
Postpartum Hemorrhage
Interventions
Tranexamic Acid 1000 mg/10ml normal saline infusion
Drug
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
18 Years to 54 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
San Diego, California
Conditions
Postpartum Hemorrhage
Interventions
Carbetocin, Placebo, Placebo and Moxifloxacin
Drug
Lead sponsor
Ferring Pharmaceuticals
Industry
Eligibility
18 Years to 45 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Tempe, Arizona
Completed Not applicable Interventional Accepts healthy volunteers

Postpartum Video Education

NCT05159726
Conditions
Postpartum Hemorrhage, Postpartum Preeclampsia, Postpartum Sepsis, Postpartum Depression, Patient Empowerment, Patient Education, Postpartum Care
Interventions
Video Education
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
New Haven, Connecticut
Conditions
Obstetric Complication, Postpartum Hemorrhage, Postpartum Endometritis
Interventions
CeFAZolin 1000 MG, Clindamycin 900 MG in 6 ML Injection
Drug
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Post Partum Hemorrhage
Interventions
Novel PPH Risk Prediction Model - Comparator Arm B
Behavioral
Lead sponsor
Holly Ende
Other
Eligibility
Female only
Enrollment
10,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Postpartum Period
Interventions
IUD, Diary
Device · Other
Lead sponsor
Baystate Medical Center
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Springfield, Massachusetts
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Prevention of Postpartum Hemorrhage With Tranexamic Acid

NCT03287336
Conditions
Postpartum Hemorrhage
Interventions
Tranexamic Acid
Drug
Lead sponsor
George Washington University
Other
Eligibility
18 Years to 49 Years · Female only
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Conditions
Blood Loss Massive, Trauma, Hemorrhage, Postpartum
Interventions
Quantra System
Diagnostic Test
Lead sponsor
HemoSonics LLC
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
El Paso, Texas
Conditions
Postpartum Hemorrhage, Immediate Postpartum Hemorrhage, Hemorrhage, Postpartum
Interventions
KOKO Device
Device
Lead sponsor
KOKO Medical Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
17
States / cities
Birmingham, Alabama • Newark, Delaware • Miami, Florida + 12 more
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Second-Line Uterotonics in Postpartum Hemorrhage: A Randomized Clinical Trial

NCT03584854
Conditions
Postpartum Hemorrhage, Uterine Atony
Interventions
15-methyl prostaglandin F2α, Methylergonovine Maleate
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Completed No phase listed Observational Accepts healthy volunteers Results available

Coagulation Factor Changes Associated With Postpartum Hysterectomies

NCT00456547
Conditions
Obstetric Labor Complications, Hemorrhage, Complications; Cesarean Section
Interventions
Blood Draw
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2006
U.S. locations
1
States / cities
Chicago, Illinois
Completed No phase listed Observational Accepts healthy volunteers

The PPHgb Study: Non-Invasive Hemoglobin Measurement

NCT05046964
Conditions
Postpartum Hemorrhage
Interventions
Masimo Radical-7 Pulse CO-Oximeter
Device
Lead sponsor
George Washington University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
119 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Conditions
Postpartum Hemorrhage
Interventions
Jada® System
Device
Lead sponsor
Alydia Health
Industry
Eligibility
Female only
Enrollment
809 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
16
States / cities
Loma Linda, California • Newark, Delaware • Gainesville, Georgia + 11 more
Conditions
Wound; Rupture, Surgery, Cesarean Section, Postpartum Hemorrhage, Surgery
Interventions
Hemoleven
Biological
Lead sponsor
Laboratoire français de Fractionnement et de Biotechnologies
Industry
Eligibility
6 Months and older
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Postpartum Hemorrhage
Interventions
Saline delivered using an intrauterine pressure catheter (IUPC)
Combination Product
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older · Female only
Enrollment
700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Houston, Texas
Conditions
Postpartum Hemorrhage
Interventions
CAPP use
Device
Lead sponsor
University of New Mexico
Other
Eligibility
Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Albuquerque, New Mexico
Recruiting Phase 3 Interventional

EVE TRIAL , ALMA SYSTAM

NCT06646653
Conditions
Postpartum Haemorrhage (PPH), PPH, Postpartum Hemorrhage (Primary)
Interventions
Alma System
Device
Lead sponsor
ResQ Medical Ltd
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Brooklyn, New York
Conditions
Postpartum Hemorrhage, Immediate
Interventions
Intrauterine balloon tamponade
Device
Lead sponsor
Denver Health and Hospital Authority
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Denver, Colorado