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Showing 1–24 of 31 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Hemorrhoid Clear all
Completed Not applicable Interventional Results available

Safety and Efficacy Study of HET Bipolar System for Treatment of Stage I and Stage II Hemorrhoids

NCT01841970
View directory record Official record
Conditions
Hemorrhoids, Internal
Interventions
HET Bipolar System
Device
Lead sponsor
Medtronic - MITG
Industry
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 15, 2017 · Synced Jul 23, 2026, 11:24 AM EDT
Completed Phase 3 Interventional Results available

Study to Evaluate Postoperative Analgesia in Subjects Undergoing Hemorrhoidectomy

NCT00744848
View directory record Official record
Conditions
Hemorrhoids
Interventions
Bupivacaine HCl, SKY0402
Drug
Lead sponsor
Pacira Pharmaceuticals, Inc
Industry
Eligibility
18 Years and older
Enrollment
204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
20
States / cities
Birmingham, Alabama • Montgomery, Alabama • Pasadena, California + 16 more
Source: ClinicalTrials.gov public record
Updated Aug 5, 2013 · Synced Jul 23, 2026, 11:24 AM EDT
Terminated Not applicable Interventional

Comparison Study of Hemorrhoid Surgery Using the Enseal Device to Standard Hemorrhoid Surgical Techniques

NCT01422473
View directory record Official record
Conditions
Hemorrhoids
Interventions
EnSeal Trio Tissue Sealing Device
Device
Lead sponsor
Swedish Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 4, 2013 · Synced Jul 23, 2026, 11:24 AM EDT
Completed Not applicable Interventional

Perineal Self-Acupressure

NCT01867944
View directory record Official record
Conditions
Chronic Constipation, Constipation, Hemorrhoids
Interventions
Perineal Self-Acupressure, Educational Control
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2013
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 27, 2016 · Synced Jul 23, 2026, 11:24 AM EDT
Completed Not applicable Interventional Results available

Safety and Performance of the Covidien EEA Hemorrhoid and Prolapse Stapling Set in a Hemorrhoidopexy Procedure

NCT01169311
View directory record Official record
Conditions
Hemorrhoid
Interventions
Hemorrhoidopexy
Device
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years to 80 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 5, 2014 · Synced Jul 23, 2026, 11:24 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Continuous Infusion of Local Anesthetic for Optimal Post Operative Pain Control Following Hemorrhoidectomy

NCT01099605
View directory record Official record
Conditions
Hemorrhoids
Interventions
placement of a continuous infusion pump, continuous infusion pump of bupivacaine
Device
Lead sponsor
United States Naval Medical Center, Portsmouth
Federal
Eligibility
18 Years to 99 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Portsmouth, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 19, 2025 · Synced Jul 23, 2026, 11:24 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Post Hemorrhoidectomy Anorectal Pain

NCT03240185
View directory record Official record
Conditions
Hemorrhoid Pain
Interventions
deep breathing exercises
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 5, 2020 · Synced Jul 23, 2026, 11:24 AM EDT
Completed Not applicable Interventional Results available

Comparison Study of Surgical Staplers for the Treatment of Hemorrhoids

NCT01306877
View directory record Official record
Conditions
Hemorrhoids
Interventions
EEA Hemorrhoid and Prolapse Stapling Set, Endosurgery Proximate PPH03 Stapling Set
Device
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years to 85 Years
Enrollment
149 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Oct 28, 2014 · Synced Jul 23, 2026, 11:24 AM EDT
Completed Not applicable Interventional

Trans-anal Hemorrhoidal Dearterialization (THD) vs. Hemorrhoidectomy

NCT01244672
View directory record Official record
Conditions
Hemorrhoids
Interventions
Ferguson, THD
Procedure
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Oct 4, 2012 · Synced Jul 23, 2026, 11:24 AM EDT
Recruiting Not applicable Interventional

Hemorrhoidal Artery Embolization: Longitudinal Impact On Symptoms (HELIOS)

NCT07179601
View directory record Official record
Conditions
Internal Hemorrhoids, HAE
Interventions
Hemorrhoidal artery embolization
Procedure
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 90 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 1, 2026 · Synced Jul 23, 2026, 11:24 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Efficacy of Rectal Infiltration of Exparel for Analgesic Benefit Following Hemorrhoidectomy

NCT02104414
View directory record Official record
Conditions
Hemorrhoid
Interventions
Exparel, Bupivacaine HCl with Epinephrine, Normal Saline
Drug
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
21 Years to 65 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 3, 2018 · Synced Jul 23, 2026, 11:24 AM EDT
Not listed No phase listed Observational

Multicenter Prospective Trial on Hemorrhoids

NCT03245086
View directory record Official record
Conditions
Hemorrhoids
Interventions
Transanal hemorrhoid dearterialization, Ferguson hemorrhoidectomy
Device · Procedure
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
492 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Aug 9, 2017 · Synced Jul 23, 2026, 11:24 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

The Sequestration of Holistic Stress Management Techniques for Adults

NCT06098755
View directory record Official record
Conditions
Stress, Job, PTSD, Hypervigilance, Hyperthyroidism, Migraine, Migraine With Aura, Immunodeficiency, Sickle Cell Trait, Sickle Cell Disease, Anemia, Sickle Cell, Anemia, Fatigue, Anxiety, Depression, Flat Feet, Lordosis, TBI (Traumatic Brain Injury), Rheumatoid Arthritis, Arthritis, Masturbation, Priapism, Erectile Dysfunction, Flight Reaction, Hypertension, Sexual Arousal Disorder, Hemorrhoids, Fibroid
Interventions
Holistic Medicine (HM)
Behavioral
Lead sponsor
Goddess Zena I. Jones
Other
Eligibility
22 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Anchorage, Alaska
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Jul 23, 2026, 11:24 AM EDT
Completed Not applicable Interventional

Comparison Between Two Endoscopic Treatments of Bleeding Internal Hemorrhoids:Band Ligation and Electrocoagulation Probe

NCT00630669
View directory record Official record
Conditions
Hemorrhoids
Interventions
Rubber band ligation, Bipolar coagulation
Procedure
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2001
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 6, 2008 · Synced Jul 23, 2026, 11:24 AM EDT
Completed Phase 2 Interventional

Safety and Efficacy of CITI-002 in Adult Patients With Moderate Grade Hemorrhoids

NCT05348200
View directory record Official record
Conditions
Hemorrhoids
Interventions
Monad 1, Monad 2, Monad 3, Combination - CITI-002 (low dose), Combination - CITI-002 (high dose)
Drug
Lead sponsor
Citius Pharmaceuticals, Inc.
Industry
Eligibility
18 Years and older
Enrollment
304 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
16
States / cities
Huntsville, Alabama • Tucson, Arizona • Chula Vista, California + 12 more
Source: ClinicalTrials.gov public record
Updated Aug 30, 2023 · Synced Jul 23, 2026, 11:24 AM EDT
Completed Not applicable Interventional

Pre-Emptive Analgesia in Ano-Rectal Surgery

NCT02402543
View directory record Official record
Conditions
Hemorrhoids, Fissure in Ano, Rectal Fistula, Anal Condyloma
Interventions
Gabapentin, Ketamine, Acetaminophen, Dexamethasone, Placebo
Drug
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
2
States / cities
Burlington, Vermont • Colchester, Vermont
Source: ClinicalTrials.gov public record
Updated Jan 15, 2018 · Synced Jul 23, 2026, 11:24 AM EDT
Completed Phase 2 Interventional Results available

Evaluate Safety and Efficacy of 25 mg Hydrocortisone Acetate Suppositories in Treatment of Internal Hemorrhoids

NCT03335774
View directory record Official record
Conditions
Internal Hemorrhoids
Interventions
Hydrocortisone Acetate Suppository, 25 mg (Nivagen), Placebo (Vehicle) Suppository (Nivagen)
Drug
Lead sponsor
Nivagen Pharmaceuticals Inc.
Industry
Eligibility
18 Years and older
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 12, 2022 · Synced Jul 23, 2026, 11:24 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

EnSeal Device Versus Ferguson Technique in Hemorrhoidectomy

NCT00853853
View directory record Official record
Conditions
Hemorrhoids
Interventions
EnSeal Device, Ferguson Hemorrhoidectomy technique
Device · Procedure
Lead sponsor
Steven Schechter, M.D.
Other
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Nov 19, 2012 · Synced Jul 23, 2026, 11:24 AM EDT
Completed Not applicable Interventional

Use of Human Dehydrated Amnion Chorion Allograft in Closed Hemorroidectomy

NCT03479489
View directory record Official record
Conditions
External Hemorrhoid, External Hemorrhoid Thrombosed
Interventions
Human dehydrated amnion chorion allograft
Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 17, 2019 · Synced Jul 23, 2026, 11:24 AM EDT
Completed Not applicable Interventional

Study of a New Circular Anal Dilator

NCT00693459
View directory record Official record
Conditions
Hemorrhoids
Interventions
Circular Anal Dilator for Transanal Hemorrhoidectomy
Device
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 14, 2022 · Synced Jul 23, 2026, 11:24 AM EDT
Enrolling by invitation Not applicable Interventional

Rectal Evacuation Disorders and Straining-associated Symptoms in Bleeding Hemorrhoids

NCT07161765
View directory record Official record
Conditions
Bleeding Hemorrhoids, Rectal Evacuation Disorders
Interventions
Anorectal manometry
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Jul 23, 2026, 11:24 AM EDT
Completed Phase 2 Interventional

Safety and Efficacy Study of Anucort HC TM 25mg Rectal Suppositories to Treat Symptomatic Internal Hemorrhoids

NCT01913158
View directory record Official record
Conditions
Internal Hemorrhoids
Interventions
Anucort-HC, 25 Mg Rectal Suppository, Placebo suppository
Drug
Lead sponsor
G & W Laboratories Inc.
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
3
States / cities
Huntsville, Alabama • Sanford, Florida • Wyoming, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 2, 2016 · Synced Jul 23, 2026, 11:24 AM EDT
Recruiting Not applicable Interventional

Rectal Arterial Embolization vs Band Ligation for the Treatment of Internal hemOrrhoidS

NCT07559630
View directory record Official record
Conditions
Hemorrhoidal Bleeding, Hemorrhoids, Internal, HAE, RBL
Interventions
Hemorrhoidal Artery Embolization, Rubber Band Ligation
Device · Procedure
Lead sponsor
Jessica K. Stewart, MD
Other
Eligibility
18 Years to 89 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Jul 23, 2026, 11:24 AM EDT
Recruiting No phase listed Observational

Outcomes and Quality of Life Following Rectal Artery Embolization for Bleeding Internal Hemorrhoids

NCT06106269
View directory record Official record
Conditions
Internal Hemorrhoid
Interventions
Rectal Artery Embolization
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Jul 23, 2026, 11:24 AM EDT