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Showing 1–24 of 41 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Hepatectomy Clear all
Terminated Not applicable Interventional Results available

Isoflurane Preconditioning for Liver Resections

NCT01031550
View directory record Official record
Conditions
Liver Disease
Interventions
isoflurane, propofol
Drug
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 19, 2017 · Synced Jul 21, 2026, 10:21 PM EDT
Terminated Phase 2 Interventional Results available

Pre- and Post-operative FOLFOX Based Therapy for Patients With Colorectal Cancer With Liver Involvement

NCT00537823
View directory record Official record
Conditions
Colorectal Cancer, Metastases
Interventions
Cetuximab, Bevacizumab, Leucovorin, Oxaliplatin, Fluorouracil
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 19, 2016 · Synced Jul 21, 2026, 10:21 PM EDT
Completed Phase 2 Interventional Results available

Liver Resection and Floxuridine Plus Fluorouracil and Leucovorin in Treating Patients With Liver Metastases From Colorectal Cancer

NCT00002842
View directory record Official record
Conditions
Colorectal Cancer, Metastatic Cancer
Interventions
floxuridine, fluorouracil, leucovorin calcium, adjuvant therapy, conventional surgery
Drug · Procedure
Lead sponsor
City of Hope Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1994 – 2014
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Apr 10, 2017 · Synced Jul 21, 2026, 10:21 PM EDT
Completed No phase listed Observational

Adult-to-Adult Living Donor Liver Transplantation Study

NCT00096733
View directory record Official record
Conditions
Cirrhosis, Hepatitis C, Hepatocellular Carcinoma
Interventions
Not listed
Lead sponsor
Arbor Research Collaborative for Health
Other
Eligibility
18 Years and older
Enrollment
2,470 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
9
States / cities
Los Angeles, California • San Francisco, California • Denver, Colorado + 6 more
Source: ClinicalTrials.gov public record
Updated Aug 28, 2017 · Synced Jul 21, 2026, 10:21 PM EDT
Completed Phase 2 Interventional Results available

Perioperative MVT-5873, a Fully Human Monoclonal Antibody Against a CA 19-9 Epitope, for Operable CA 19-9 Producing Pancreatic Cancers, Cholangiocarcinomas, and Metastatic Colorectal Cancers

NCT03801915
View directory record Official record
Conditions
Colon Cancer, Pancreatic Cancer, Cholangiocarcinoma, Metastatic Colon Carcinoma, Liver Metastasis
Interventions
MVT-5873, pancreatectomy or hepatectomy
Drug · Procedure
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 20, 2023 · Synced Jul 21, 2026, 10:21 PM EDT
Recruiting Not applicable Interventional

Accelerated Recovery After MIS Hepatectomy (ARAMIS Hep) to Support Early Discharge for Patients Undergoing Minimally Invasive Liver Resection

NCT05879159
View directory record Official record
Conditions
Liver
Interventions
Questionnaires
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Jul 21, 2026, 10:21 PM EDT
Recruiting Phase 3 Interventional

A Study of Methylprednisolone in People Having Liver Surgery

NCT07507643
View directory record Official record
Conditions
Hepatectomy
Interventions
Methylprednisolone
Drug
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
19
States / cities
Chicago, Illinois • Indianapolis, Indiana • Iowa City, Iowa + 14 more
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Jul 21, 2026, 10:21 PM EDT
Recruiting Not applicable Interventional

Novel Method to Assess Hepatic Regeneration and Predict Hepatic Related Morbidity After Partial Hepatectomy

NCT06681818
View directory record Official record
Conditions
Liver Cancer Adult, Liver Regeneration
Interventions
carbon monoxide measurement via smokerlyzer
Other
Lead sponsor
Englewood Hospital and Medical Center
Other
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2039
U.S. locations
1
States / cities
Englewood, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 22, 2025 · Synced Jul 21, 2026, 10:21 PM EDT
Terminated No phase listed Observational

A 48 Subject Study Using Non-invasive Multi-Technology Measurements for Early Detection of Ongoing Hemorrhage

NCT04814810
View directory record Official record
Conditions
Occult Bleeding, Hemorrhage, Hemorrhagic Shock
Interventions
Not listed
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 4, 2022 · Synced Jul 21, 2026, 10:21 PM EDT
Active, not recruiting Phase 3 Interventional

Patient Controlled Epidural Analgesia Versus Intravenous Patient Controlled Analgesia for Post-Operative Pain Control in Patients Undergoing Elective Liver Resection

NCT02523443
View directory record Official record
Conditions
Liver Cancer, Pain Management
Interventions
IV PCA, PCEA
Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
231 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2026
U.S. locations
3
States / cities
Basking Ridge, New Jersey • Commack, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 21, 2025 · Synced Jul 21, 2026, 10:21 PM EDT
Not listed No phase listed Observational

Validate the Difficulty Scoring System and Develop a Novel Scoring System for Laparoscopic and Robotic Liver Resections

NCT05224739
View directory record Official record
Conditions
Liver Diseases
Interventions
Minimally Invasive Liver Resection
Procedure
Lead sponsor
Methodist Health System
Other
Eligibility
18 Years to 79 Years
Enrollment
150 participants
Timeline
2021 – 2024
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 26, 2024 · Synced Jul 21, 2026, 10:21 PM EDT
Active, not recruiting Phase 3 Interventional

The HeLiX (Hemorrhage During Liver Resection: traneXamic Acid) Trial

NCT02261415
View directory record Official record
Conditions
Cancer, Tumour, Surgery
Interventions
Tranexamic acid (TXA), Normal saline
Drug
Lead sponsor
Sunnybrook Health Sciences Centre
Other
Eligibility
18 Years and older
Enrollment
1,386 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 25, 2022 · Synced Jul 21, 2026, 10:21 PM EDT
Not listed No phase listed Observational

Effect of Materials for Subcuticular Suture (Quill vs. Monocryl) on Complications After Liver Resection

NCT04906174
View directory record Official record
Conditions
Liver and Intrahepatic Bile Duct Neoplasm
Interventions
Electronic Health Record Review
Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 11, 2023 · Synced Jul 21, 2026, 10:21 PM EDT
Active, not recruiting No phase listed Observational

Health Related Quality of Life Following Hepatectomy for Colorectal Liver Metastasis: Global and Disease Specific Changes Over Time

NCT02399995
View directory record Official record
Conditions
Colorectal Liver Metastasis
Interventions
HRQoL questionnaires.
Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
219 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2027
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Jul 21, 2026, 10:21 PM EDT
Recruiting Phase 1Phase 2 Interventional

Safety of HRX215 in Patients After Minor and Major Liver Resection

NCT06638502
View directory record Official record
Conditions
Liver Resection, Colorectal Carcinoma Liver Metastases
Interventions
HRX215 capsules, Placebo capsules
Drug
Lead sponsor
HepaRegeniX GmbH
Industry
Eligibility
18 Years to 75 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
3
States / cities
Baltimore, Maryland • Rochester, Minnesota • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Jul 21, 2026, 10:21 PM EDT
Not listed No phase listed Observational

Tampa Associating Microwave Liver Ablation With Portal Vein Ligation for Staged Hepatectomy (TAMLAPS)

NCT03739164
View directory record Official record
Conditions
Liver Cancer, Liver Tumor, Hepatocellular Carcinoma, Hilar Cholangiocarcinoma
Interventions
Not listed
Lead sponsor
Florida Hospital Tampa Bay Division
Other
Eligibility
18 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Nov 12, 2018 · Synced Jul 21, 2026, 10:21 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Metabolomics of Liver Regeneration Following Partial Hepatectomy in Healthy Living Liver Donors

NCT01922323
View directory record Official record
Conditions
Liver Insufficiency
Interventions
Not listed
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 27, 2017 · Synced Jul 21, 2026, 10:21 PM EDT
Recruiting Phase 4 Interventional

Erector Spinae Plane Block Catheters and Intrathecal Morphine for Hepatic Resection

NCT04849455
View directory record Official record
Conditions
Hepatic Resection, Acute Pain, Anesthesia, Anesthesia, Local
Interventions
0.2% ropivacaine local anesthetic continuous erector spinae plane block, 0.2% ropivacaine local anesthetic superficially taped continuous erector spinae plane block, Spinal Morphine
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jun 6, 2022 · Synced Jul 21, 2026, 10:21 PM EDT
Recruiting Phase 2 Interventional

ctDNA-Directed Post-Hepatectomy Chemotherapy for Patients With Resectable Colorectal Liver Metastases

NCT05062317
View directory record Official record
Conditions
Liver Metastases
Interventions
Leucovorin, 5-FLUOROURACIL, Oxaliplatin, Irinotecan, Capecitabine, Bevacizumab
Drug
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Jul 21, 2026, 10:21 PM EDT
Recruiting No phase listed Observational

DRAGON Registry - International Multicenter Registry and Medical Image Bank for Patients With Primarily Unresectable Liver Cancer or Liver Metastases That Underwent Combined Portal and Hepatic Vein Embolization (PVE/HVE) to Increase Future Liver Remnant Before Resection.

NCT07717437
View directory record Official record
Conditions
Liver Cancer, Liver Metastases
Interventions
Not listed
Lead sponsor
Maastricht University Medical Center
Other
Eligibility
18 Years and older
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2032
U.S. locations
3
States / cities
Chicago, Illinois • Rochester, Minnesota • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Jul 21, 2026, 10:21 PM EDT
Completed Not applicable Interventional

A Phase II Study of the Effect of a Low Calorie Diet on Patients Undergoing Liver Resection

NCT01645852
View directory record Official record
Conditions
Nonalcoholic Fatty Liver Disease, Hepatic Steatosis, Steatohepatitis
Interventions
Optifast 800
Dietary Supplement
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
3
States / cities
Worcester, Massachusetts • Lebanon, New Hampshire • Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Feb 7, 2017 · Synced Jul 21, 2026, 10:21 PM EDT
Completed Not applicable Interventional Results available

Postoperative Heme Oxygenase Induction and Carbon Monoxide Production as a Novel Method to Assess Hepatic Regeneration and Predict Hepatic Related Morbidity After Partial Hepatectomy

NCT04195438
View directory record Official record
Conditions
Liver Cancer
Interventions
CO Testing Pre/Post Hepatic Resection, ABG Testing Pre/Post Hepatic Resection, CT Evaluations
Procedure · Diagnostic Test
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2024
U.S. locations
1
States / cities
Glen Burnie, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 20, 2024 · Synced Jul 21, 2026, 10:21 PM EDT
Active, not recruiting No phase listed Observational

Hepatic Resection for Metastatic Pancreatic Cancer

NCT02892305
View directory record Official record
Conditions
Pancreatic Neoplasms, Neoplasm Metastasis, Liver Metastases
Interventions
Hepatic Resection or Ablation with Pancreaticoduodenectomy
Procedure
Lead sponsor
Duke University
Other
Eligibility
18 Years to 90 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 5, 2025 · Synced Jul 21, 2026, 10:21 PM EDT
Completed No phase listed Observational

Does a Minimally Invasive Approach to Liver Resection Improve Postoperative Outcomes?

NCT07169877
View directory record Official record
Conditions
Hepatic Neoplasms
Interventions
Not listed
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
9,411 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 11, 2025 · Synced Jul 21, 2026, 10:21 PM EDT